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| 1 | Treatment of diffuse intrinsic brainstem gliomas: failed approaches and future strategies显示文摘 | Frazier JL Lee J Thomale UW Noggle JC Cohen K J Jallo GI | 2009 | 中国神经肿瘤杂志2009，7，3： | 10 |
| 2 | Sequential transcatheter arterial chemoembolization and portal vein embolization before right hemihepatectomy in patients with hepatocellular carcinoma显示文摘Background:Recent studies showed that sequential selective transcatheter arterial chemoembolization(TACE)and portal vein embolization(PVE)provided better future liver remnant(FLR)regeneration rate and disease-free survival following surgery compared with PVE alone.The present study aimed to clarify whether preoperative sequential TACE and PVE before right hemihepatectomy can reduce postoperative hepatocellular carcinoma(HCC)recurrence and improve long-term disease-free and overall survival.Methods:Recurrence and survival outcomes were retrospectively evaluated in 205 patients with HCC who underwent right hemihepatectomy by a single surgeon from November 1993 to November 2017.Patients were divided into four groups according to the procedure performed before the surgery:sequential TACE and PVE(TACE-PVE),PVE-only,TACE-only,or na?ve control groups.The baseline patient and tumor characteristics,postoperative outcomes,recurrence-free survival and overall survival were analyzed.Results:Baseline patient and tumor characteristics upon diagnosis were similar in all four groups,while sequential TACE and PVE were well tolerated.The TACE-PVE group had a higher mean increase in percentage FLR volume compared with that of the PVE-only group(17.46%±6.63%vs.12.14%±5.93%;P=0.001).The TACE-PVE group had significantly better overall and disease-free survival rates compared with the other groups(both P<0.001).Conclusions:Sequential TACE and PVE prior to surgery can be an effective therapeutic strategy for patients with HCC scheduled for major hepatic resection.The active application of preoperative sequential TACE and PVE for HCC would allow more patients with marginal FLR volume to become candidates for major hepatic resection by promoting compensatory FLR hypertrophy without the deterioration of basal hepatic functional reserve or tumor progression. | Gil Chun Park Sung Gyu Lee Young In Yoon Kyu Bo Sung Gi Young Ko Dong Il Gwon Dong Hwan Jung Yong Kyu Jung | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，3： | 9 |
| 3 | Differential diagnosis of left-sided abdominal pain:Primary epiploic appendagitis vs colonic diverticulitis显示文摘AIM:To investigate the clinical characteristics of left primary epiploic appendagitis and to compare them with those of left colonic diverticulitis.METHODS:We retrospectively reviewed the clinical records and radiologic images of the patients who presented with left-sided acute abdominal pain and had computer tomography(CT) performed at the time of presentation showing radiological signs of left primary epiploic appendagitis(PEA) or left acute colonic diverticulitis(ACD) between January 2001 and December 2011. A total of 53 consecutive patients were enrolled and evaluated. We also compared the clinical characteristics,laboratory findings,treatments,and clinical results of left PEA with those of left ACD.RESULTS:Twenty-eight patients and twenty-five patients were diagnosed with symptomatic left PEA and ACD,respectively. The patients with left PEA had focal abdominal tenderness on the left lower quadrant(82.1%). On CT examination,most(89.3%) of the patients with left PEA were found to have an oval fatty mass with a hyperattenuated ring sign. In cases of left ACD,the patients presented with a more diffuse abdominal tenderness throughout the left side(52.0%vs 14.3%; P = 0.003). The patients with left ACD had fever and rebound tenderness more often than those with left PEA(40.0% vs 7.1%,P = 0.004; 52.0% vs14.3%,P = 0.003,respectively). Laboratory abnormalities such as leukocytosis were also more frequently observed in left ACD(52.0% vs 15.4%,P = 0.006).CONCLUSION:If patients have left-sided localized abdominal pain without associated symptoms or laboratory abnormalities,clinicians should suspect the diagnosis of PEA and consider a CT scan. | Jeong Ah Hwang Sun Moon Kim Hyun Jung Song Yu Mi Lee Kyung Min Moon Chang Gi Moon Hoon Sup Koo Kyung Ho Song Yong Seok Kim Tae Hee Lee Kyu Chan Huh Young Woo Choi Young Woo Kang Woo Suk Chung | 2013 | World Journal of Gastroenterology2013，19，40： | 6 |
| 4 | Experimental investigation of friction coefficient in tube hydroforming显示文摘The friction coefficient between tube and die in guide zone of tube hydroforming was obtained. In hydroforming, the tube is expanded by an internal pressure against the tool wall. By pushing the tube through tool, a friction force at the contact surface between the tube and the tool occurs. In guiding zone, the friction coefficients between tube and die can be estimated from the measured axial feeding forces. In expansion zone, the friction coefficients between tube and die can be evaluated from the measured geometries of expanded tubes and FE analysis. | Hyae Kyung YI Hong Sup YIM Gun Yeop LEE Sung Mun LEE Gi Suk CHUNG Young-Hoon MOON | 2011 | Transactions of Nonferrous Metals Society of China2011，21，A01： | 5 |
| 5 | Texture tailoring and bendability improvement of rolled AZ31 alloy using {10-12} twinning: The effect of precompression levels显示文摘In this study,the texture of a rolled Mg alloy is effectively modified through the application of precompression and subsequent annealing treatment,leading to a remarkable improvement in the bending formability of the alloy at room temperature.Precompression induces lattice reorientation through{10-12}twinning,and annealing treatment reduces the stored strain energy of the precompressed material,which results in the formation of a stable grain structure with two dominant texture components.With an increase in precompression,the tensile strain in the outer region of the bending samples is accommodated to a greater extent due to more pronounced{10-12}twinning and basal slip.As a result,the bending formability of the material at room temperature improves with greater precompression.The variation in microstructure,texture,and bending behavior in relation to the degree of precompression is discussed in detail. | Jong Un Lee Ye Jin Kim Sang-Hoon Kim Jeong Hun Lee Min-Seong Kim Shi-Hoon Choi Byoung Gi Moon Young Min Kim Sung Hyuk Park | 2019 | Journal of Magnesium and Alloys2019，7，4： | 5 |
| 6 | Surgical repair of intractable chylous ascites following laparoscopic anterior resection显示文摘Chylous ascites is the accumulation of a milk-like peritoneal fluid rich in triglycerides and it is an unusual complication following surgical treatment of colorectal cancer. Conservative management is usually sufficientin patients with chylous ascites after surgery. However,we describe a patient with intractable chylous ascites after laparoscopic anterior resection for sigmoid colon cancer who failed initial conservative treatment. This patient was successfully managed by surgery. | Gi Won Ha Min Ro Lee | 2015 | World Journal of Gastroenterology2015，21，19： | 5 |
| 7 | Intrauterine midgut volvulus without malrotation:Diagnosis from the 'coffee bean sign'显示文摘Fetal midgut volvulus is quite rare, and most cases are associated with abnormalities of intestinal rotation or fixation. We report a case of midgut volvulus without malrotation, associated with a meconium pellet, during the gestation period. This 2.79 kg, 33-wk infant was born via a spontaneous vaginal delivery caused by preterm labor. Prenatal ultrasound showed dilated bowel loops with the appearance of a 'coffee bean sign'. This patient had an unusual presentation with a distended abdomen showing skin discoloration. An emergency laparotomy revealed a midgut volvulus and a twisted small bowel, caused by complicated meconium ileus. Such nonspecific prenatal radiological signs and a low index of suspicion of a volvulus during gestation might delay appropriate surgical management and result in ischemic necrosis of the bowel. Preterm labor, specific prenatal sonographic findings (for example, the coffee bean sign) and bluish discoloration of the abdominal wall could suggest intrauterine midgut volvulus requiring prompt surgical intervention. | Jun Seok Park Seong Jae Cha Beom Gyu Kim Yong Seok Kim Yoo Shin Choi In Taik Chang Gwang Jun Kim Woo Seok Lee Gi Hyeon Kim | 2008 | World Journal of Gastroenterology2008，14，9： | 4 |
| 8 | Subacute electroacupuncture at Baihui (GV 20) and Dazhui (GV 14) promotes post-stroke functional recovery via neurogenesis and astrogliosis in a photothrombotic stroke mouse model显示文摘OBJECTIVE:To investigate the optimal timing and underlying mechanism of electroacupuncture(EA)at Baihui(GV 20)and Dazhui(GV 14)for improved long-term functional recovery after focal cerebral ischemia in a photothrombotic stroke mouse model.METHODS:Totally 50 adult male C57 BL/6 J mice were assigned into 5 groups:(a)the control group,sham-operated mice(n=10);(b)the vehicle group,focal cerebral ischemia induction without EA(n=10);(c)the acute EA group,mice received EA immediately post-ischemia,followed by once-daily treatments for 7 consecutive days(n=10);(d)the subacute EA group,mice received EA 4 days post-ischemia,followed by once-daily treatments for 7 consecutive days(n=10);(e)the delayed EA group.EA stimulation(2 Hz,2 V for 20 min)was applied to acupuncture points(acupoints),Baihui(GV 20)and Dazhui(GV 14),once a day for 7 consecutive days beginning immediately(acute treatment),4 d(subacute treatment)and 10 d(delayed treatment)after focal cerebral ischemia in C57 BL/6 J mice.Behavioral assessments were conducted 21 and 28 d post-ischemia and histopathological analyses were performed 28 days post-ischemia.RESULTS:The subacute EA treatment at Baihui(GV20)and Dazhui(GV 14)significantly improved functional recovery compared to the vehicle group 28 d after ischemic brain injury,although brain atrophy was not reduced.The number of Neu N+and Neu N+/Brd U+cells as well as GFAP intensity in the ipsilateral cortex were significantly increased in the subacute group compared to the vehicle group 28 d post-ischemia.We concluded that EA stimulation 4 d post-ischemia(subacute treatment)enhanced neurogenesis and astrogliosis,likely contributing to long-term functional recovery following focal cerebral ischemia.CONCLUSION:Our findings suggest that the timing of the EA therapy at Baihui(GV 20)and Dazhui(GV 14)determines the therapeutic effects in mice with focal cerebral ischemia induced by photothrombotic occlusion. | Young-Wook Park Gi Yoon Heo Min Jae Kim Seo-Yeon Lee Byung Tae Choi Hwa Kyoung Shin | 2019 | Journal of Traditional Chinese Medicine2019，39，6： | 4 |
| 9 | Contrast-enhanced ultrasonography for the evaluation of liver fibrosis after biliary obstruction显示文摘AIM:To investigate perfusion change in contrastenhanced ultrasonography(CEUS) to evaluate liver fibrosis based on biliary obstruction using an animal model.METHODS:New Zealand white rabbits(3-4 kg) underwent bile duct ligation to form a biliary obstruction model.We performed liver CEUS and laboratory tests on the day before the operation(day 0) and every 7 postoperative days until the rabbits were sacrificed.After CEUS,signal intensity of liver parenchyma with a time-intensity curve was analyzed.Perfusion parameters were automatically calculated from regionof-interests,including peak signal intensity,mean transit time,area under the curve and time to peak.Histological grades of liver fibrosis were assessed according to the Metavir score system immediately after sacrifice.Generalized estimating equations were used to analyze the association between liver fibrosis grades and perfusion parameters for statistical analysis.The perfusion parameters were measured on the last day and the difference between day 0 and the last day were evaluated.RESULTS:From the nine rabbits,histological grades of liver fibrosis were grade 1 in one rabbit,grade 2 and 3 in three rabbits each,and grade 4 in two rabbits.Among the four CEUS parameters,only the peak signal intensity measured on the last day demonstrated a significant association with liver fibrosis grades(OR =1.392,95%CI:1.114-1.741,P =0.004).The difference in peak signal intensity between day 0 and the last dayalso demonstrated an association with liver fibrosis(OR =1.191,95%CI:0.999-1.419,P =0.051).The other parameters tested,including mean transit time,area under the curve,and time to peak,showed no significant correlation with liver fibrosis grades.CONCLUSION:This animal study demonstrates that CEUS can be used to evaluate liver fibrosis from biliary obstruction using peak signal intensity as a parameter. | Hyun Joo Shin Eun Young Chang Hye Sun Lee Jung Hwa Hong Gyuri Park Hyun Gi Kim Myung-Joon Kim Mi-Jung Lee | 2015 | World Journal of Gastroenterology2015，21，9： | 4 |
| 10 | Cholecystocolic fistula caused by gallbladder carcinoma:Preoperatively misdiagnosed as hepatic colon carcinoma显示文摘Cholecystocolic fistula secondary to gallbladder carcinoma is extremely rare and has been reported in very few studies. Most cholecystocolic fistulae are late complications of gallstone disease, but can also develop following carcinoma of the gallbladder when the necrotic tumor penetrates into the adjacent colon. Although no currently available imaging technique has shown great accuracy in recognizing cholecystocolic fistula, abdominopelvic computed tomography may show fistulous communication and anatomical details.Herein we report an unusual case of cholecystocolic fistula caused by gallbladder carcinoma, which was preoperatively misdiagnosed as hepatic flexure colon carcinoma. | Gi Won Ha Min Ro Lee Jong Hun Kim | 2015 | World Journal of Gastroenterology2015，21，15： | 3 |
| 11 | High prevalence of osteoporosis in patients with gastric adenocarcinoma following gastrectomy显示文摘AIM: To evaluate the prevalence and predictive factors of osteoporosis in patients with gastric adenocarcinoma after gastrectomy. METHODS: The study included 133 patients diagnosed with gastric adenocarcinoma but who did not undergo prior diagnostic work-up for osteoporosis. Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DXA) and vertebral deformity was assessed by plain X-rays. We evaluated the effects of age, sex, body mass index (BMI), anemia, back pain, vertebral deformity, tumor staging, reconstruction type, and past medical history to determine predictive factors of osteoporosis in these patients. RESULTS: The prevalence of osteoporosis in the lumbar spine was 38.3% (male, 28.9%; female, 54.0%), and 15.0% in the femoral neck (male, 10.8%; female, 22.0%). The vertebral deformity rate was 46.6% (male, 43.4%; female, 52.0%). Age, BMI and hemoglobin correlated with BMD (P < 0.01). In males, anemia and age > 64 years were independent predictive factors of osteoporosis in multivariate analysis. In females, back pain was an independent factor for osteoporosis. CONCLUSION: The results of this study revealed that prevalence of osteoporosis and vertebral bone deformity rate were high in gastric cancer patients, regardless of post-gastrectomy duration and operation type. Early diagnosis and a proper management plan must be established in these patients. | Jung Sub Lim Sang Bum Kim Ho-Yoon Bang Gi Jeong Cheon Jong-Inn Lee | 2007 | World Journal of Gastroenterology2007，13，48： | 3 |
| 12 | A case of Clostridium difficile infection complicated by acute respiratory distress syndrome treated with fecal microbiota transplantation显示文摘Acute respiratory distress syndrome is a life-threatening disorder caused mainly by pneumonia.Clostridium difficile infection(CDI)is a common nosocomial diarrheal disease.Disruption of normal intestinal flora by antibiotics is the main risk factor for CDI.The use of broadspectrum antibiotics for serious medical conditions can make it difficult to treat CDI complicated by acute respiratory distress syndrome.Fecal microbiota transplantation is a highly effective treatment in patients with refractory CDI.Here we report on a patient with refractory CDI and acute respiratory distress syndrome caused by pneumonia who was treated with fecal microbiota transplantation. | Ji Eun Kim Tae-Geun Gweon Chang Dong Yeo Young-Seok Cho Gi Jun Kim Jae Young Kim Jong Wook Kim Hyunho Kim Hye Won Lee Taeseok Lim Hyoju Ham Hyun Jin Oh Yeongbok Lee Jaeho Byeon Sung Soo Park | 2014 | World Journal of Gastroenterology2014，20，35： | 3 |
| 13 | The Use of Adjusted Preoperative CA 19-9 to Predict the Recurrence of Resectable Pancreatic Cancer显示文摘 | Chang Moo Kang Jun Young Kim Gi Hong Choi Kyung Sik Kim Jin Sub Choi Woo Jung Lee Byong Ro Kim | 2007 | Journal of Surgical Research2007，，： | 3 |
| 14 | Effect of esterification reaction of citric acid and ethylene glycol on the formation of multi-shelled cobalt oxide powders with superior electrochemical properties显示文摘第一次,在这研究,聚合先锋用弄干过程的一朵大规模水花在蛋黄壳粉末的准备被使用了。在柠檬性的酸的 carboxyl 组和在微滴内的乙烯乙二醇的氢氧根组之间的酯化作用反应在微滴的弄干的过程期间生产了器官的聚合物。在弄干过程的水花期间,聚合先锋与优异电气化学的性质启用了多壳钴氧化物蛋黄壳粉末的形成。在在 300, 400,和 500 PLD 的蛋黄壳粉末 treated 以后的粒子的壳的最大的数字(30 或 40 ? mg/m < 啜 class= “ a-plus-plus ” > 2 一次每 4 ? 星期) 。PLD 被开始 2 ? 在 temsirolimus 的开始以后的星期。FDG-PET/CT 在 bas 被执行吗?? | Gi Dae Park Jong-Heun Lee Jung-Kul Lee Yun Chan Kang | 2014 | Nano Research2014，7，12： | 2 |
| 15 | Influence of microstructure on the dielectric and piezoelectric properties of lead Zieconate titanate-polymer composites显示文摘 | LEE H G KIM Ho Gi | 1989 | J Am ceram soc1989，72，6： | 2 |
| 16 | Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA显示文摘AIM: To investigate the performance of Gadofluorine P-enhanced magnetic resonance imaging(MRI) on the diagnosis of diabetes in a streptozotocin(STZ)-induced diabetic rat model.METHODS: Fischer 344 rats were treated with STZ.Rats not treated with STZ served as controls. T1-weighted MRI was performed using a 3T scanner before and after the injection of Gd-DOTA or Gadofluorine P(6 diabetic rats, 5 controls). The normalized signal intensity(SI) and the enhancement ratio(ER) of the pancreas were measured at each time point, and the values were compared between the normal and diabetic rats using the Mann-Whitney test. In addition,the values were correlated with the mean islet number.Optimal cut-off values were calculated using a positive test based on receiver operating characteristics.Intrapancreatic Gd concentration after the injection of each contrast media was measured using laser ablation-inductively coupled plasma-mass spectrometry in a separate set of rats(4 diabetic rats, 4 controls for Gadofluorine P; 2, 2 for Gd-DOTA).RESULTS: The normalized SI and ER of the pancreas using Gd-DOTA were not significantly different between diabetic rats and controls. With Gadofluorine P, the values were significantly higher in the diabetic rats than in the control rats 30 min after injection(P < 0.05). The area under the receiver operating characteristic curve that differentiated diabetic rats from the control group was greater for Gadofluorine P than for Gd-DOTA(0.967 vs 0.667, P = 0.085). An increase in normalized SI 30 min after Gadofluorine P was correlated with a decrease in the mean number of islets(r 2 = 0.510, P = 0.014). Intra-pancreatic Gd was higher in rats with Gadofluorine P injection than Gd-DOTA injection(Gadofluorine P vs Gd-DOTA, 7.37 vs 0.00, P < 0.01). A significant difference in the concentration of intrapancreatic Gd was observed between the control and diabetic animals that were sacrificed 30 min after Gadofluorine P injection(control vs diabetic, 3.25 ng/g vs 10.55 ng/g, P < 0.05)CONCLUSION: In this STZ-induced diabetes rat model,Gadofluorine P-enhanced MRI of the pancreas showed high accuracy in the diagnosis of diabetes. | Hye Rim Cho Youkyung Lee Philip Doble David Bishop Dominic Hare Young-Jae Kim Kwang Gi Kim Hye Seung Jung Kyong Soo Park Seung Hong Choi Woo Kyung Moon | 2015 | World Journal of Gastroenterology2015，21，19： | 2 |
| 17 | Outcome after curative resection for a huge (≥10 cm) hepatocellular carcinoma and prognostic significance of gross tumor classification显示文摘 | Gi Hong Choi Dai Hoon Han Dong Hyun Kim Sae Byeol Choi Chang Moo Kang Kyung Sik Kim Jin Sub Choi Young Nyun Park Jun Yong Park Do Young Kim Kwang-Hyub Han Chae Yoon Chon Woo Jung Lee | 2009 | The American Journal of Surgery2009，，5： | 2 |
| 18 | Trigonelline attenuates the adipocyte differentiation and lipid accumulation in 3T3-L1 cells显示文摘 | Soundharrajan Ilavenil Mariadhas Valan Arasu Jeong-Chae Lee Da Hye Kim Sang Gun Roh Hyung Su Park Gi Jun Choi Vijayakumar Mayakrishnan Ki Choon Choi | 2013 | Phytomedicine2013，，： | 2 |
| 19 | Quantitative analysis of mechanical properties associated with aging treatment and microstructure in Mg-Al-Zn alloys through machine learning显示文摘The present study proposes a methodology for predicting the mechanical properties of AZ61 and AZ91alloys associated with microstructure,texture and aging parameters and estimating predictor importance.For this,we investigate quantitative correlations between microstructure,texture and mechanical properties of aged AZ61 and AZ91 rods through machine learning.This regression analysis focuses on the precipitation behavior of Mg17Al12as the main second phase of Mg-Al-Zn alloys with respect to aging conditions.To simplify data generation,only SEM images were used to quantify the features of discontinuous and continuous precipitates.To overcome the lack of data and make the most of the measured data,we devised a method to extend the existing dataset by a factor of 9 using the mean and standard deviation of the measured data.Artificial neural networks predicted tensile and compressive yield strengths and resultant yield asymmetry with a high accuracy of over 98%using 11 predictors for a total of 288datasets.Decision tree learning quantitatively assessed the importance of predictors in determining the mechanical properties of aged AZ61 and AZ91 rods. | Joung Sik Suh Byeong-Chan Suh Sang Eun Lee Jun Ho Bae Byoung Gi Moon | 2022 | Journal of Materials Science & Technology2022，，12： | 2 |
| 20 | Effect of Miscanthus sinensis var.purpurascens Flower Extract on Proliferation and Molecular Regulation in Human Dermal Papilla Cells and Stressed C57BL/6 Mice显示文摘Objective: To investigate the hair growth-promoting effect of Miscanthus sinensis var.purpurascens(MSP) flower extracton on in vitro and in vivo models.Methods: MSP flower extract was extracted in 99.9% methanol and applied to examine the proliferation of human dermal papilla cells(h DPCs) in vitro at the dose of 3.92–62.50 μg/m L and hair growth of C57 BL/6 mice in vivo at the dose of 1000 μg/m L.The expression of transforming growth factor β1(TGF-β1),hepatocyte growth factor(HGF),β-catenin,substance P was measured by relative quantitative realtime polymerase chain reaction.Histopathological and immunohistochemical analysis were performed.Results: MSP(7.81 μg/m L) down-regulated TGF-β1 and up-regulated HGF and β-catenin in h DPCs(P<0.01).MSP(1000 μg/m L)-treated mice showed the earlier transition of hair follicles from the telogen to the anagen phase.The number of mast cells was lower in the MSP-treated mice than in other groups(P<0.05 vs.NCS group).Substance P and TGF-β1 were expressed in hair follicles and skin of the MSP group lower than that in negative control.Stem cell factor in hair follicles was up-regulated in the MSP-treated mice(P<0.01).Conclusion: The MSP flower extract may have hair growth-promotion activities. | Gi Hee Jeong William A Boisvert XI Mei-zhu ZHANG Yi-lin Young-Bin Choi Sunghun Cho Sanghyun Lee Changsun Choi Bog-Hieu Lee | 2018 | Chinese Journal of Integrative Medicine2018，24，8： | 2 |
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