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| 1 | Proton pump inhibitor administration delays rebleeding after endoscopic gastric variceal obturation显示文摘AIM:To clarify the efficacy of proton pump inhibitors(PPIs)after endoscopic variceal obturation(EVO)with N-butyl-2-cyanoacrylate.METHODS:A retrospective study was performed on16 liver cirrhosis patients with gastric variceal bleeding that received EVO with injections of N-butyl-2-cyanoacrylate at a single center(Kyung Hee University Hospital at Gangdong)from January 2008 to December 2012.Medical records including patient characteristics and endoscopic findings were reviewed.Treatment results,liver function,serum biochemistry and cirrhosis etiology were compared between patients receiving PPIs and those that did not.Furthermore,the rebleeding interval was compared between patients that received PPI treatment after EVO and those who did not.RESULTS:The patient group included nine males and seven females with a mean age of 61.8±11.7years.Following the EVO procedure,eight of the 12patients that received PPIs and three of the four nonPPI patients experienced rebleeding.There were no differences between the groups in serum biochemistry or patient characteristics.The rebleeding rate was not significantly different between the groups,however,patients receiving PPIs had a significantly longer rebleeding interval compared to non-PPI patients(22.2±11.2mo vs 8.5±5.5 mo;P=0.008).The duration of PPI use was not related to the rebleeding interval.A total of six patients,who had ulcers at the injection site,exhibited a shorter rebleeding interval(16.8±5.9 mo)than patients without ulcers(19.9±3.2 mo),though this difference was not statistically significant.CONCLUSION:PPI therapy can extend the rebleeding interval,and should therefore be considered after EVO treatment for gastric varices. | Won Seok Jang Hyun Phil Shin Joung Ⅱ Lee Kwang Ro Joo Jae Myung Cha Jung Won Jeon Jun Uk Lim | 2014 | World Journal of Gastroenterology2014，20，45： | 17 |
| 2 | Therapeutic interventions for heart failure with preserved ejection fraction:A summary of current evidence显示文摘Heart failure with preserved ejection fraction(HFPEF)is common and represents a major challenge in cardiovascular medicine.Most of the current treatment of HFPEF is based on morbidity benefits and symptom reduction.Various pharmacological interventions available for heart failure with reduced ejection fraction have not been supported by clinical studies for HFPEF.Addressing the specific aetiology and aggressive risk factor modification remain the mainstay in the treatment of HFPEF.We present a brief overview of the currently recommended therapeutic options with available evidence. | Muhammad Asrar ul Haq Chiew Wong Vivek Mutha Nagesh Anavekar Kwang Lim Peter Barlis David L Hare | 2014 | World Journal of Cardiology2014，6，2： | 7 |
| 3 | Reprogramming fibroblasts into induced pluripotent stem cells with Bmil显示文摘 | Jai-Hee Moon June Seok Heo Jun Sung Kim Eun Kyoung Jun Jung Han Lee Aeree Kim Jonggun Kim Kwang Youn Whang Yong-Kook Kang Seungeun Yeo Hee-Joung Lim Dong Wook Han Dong-Wook Kim Sejong Oh Byung Sun Yoon Hans R Scholet Seungkwon You | 2011 | Cell Research2011，21，9： | 6 |
| 4 | Risk factors for perforations associated with endoscopic submucosal dissection in gastric lesions: emphasis on perforation type显示文摘 | Jun Yoo Sung Shin Kee Lee Jae Choi Jeong Wi Dong Kim Sun Lim Jae Hwang Jae Cheong Byung Yoo Kwang Lee Jin Kim Sung Cho | 2012 | Surgical Endoscopy2012，，9： | 3 |
| 5 | Consensus recommendations and review by an International Expert Panel on Interventions in Hepatocellular Carcinoma ( EPOIHCC )显示文摘 | Joong‐Won Park Deepak Amarapurkar Yee Chao Pei‐Jer Chen Jean‐Francois H. Geschwind Khean Lee Goh Kwang‐Hyub Han Masatoshi Kudo Han Chu Lee Rheun‐Chuan Lee Laurentius A. Lesmana Ho Yeong Lim Seung Woon Paik Ronnie T Poon Chee‐Kiat Tan Tawesak Tanwandee Gao | 2013 | Liver Int2013，，3： | 2 |
| 6 | Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue显示文摘在多细胞的有机体,控制预定和不对称的细胞部门(ACD ) 的程度为正确 patterning 是关键的。在在 Arabidopsis thaliana 的 embryonic 以后根开发期间,地面织物(GT ) 成熟包含内皮的另外的 ACD,它产生二不同纸巾:内皮(内部) 并且中间的外皮(外部) 。这被报导了 abscisic 酸(骆驼毛的织物) 和赤霉素(GA ) 小径涉及中间的外皮(MC ) 形成。然而,在 GT 成熟期间位于在骆驼毛的织物和 GA 之间的相互作用下面的分子的机制仍然保持大部分未知。通过 transcriptome 分析,我们识别了一以前 uncharacterized C 2 H 2-type 锌手指基因,其表情被 GA 和骆驼毛的织物调整,因此命名的 GAZ (GA- 和骆驼毛的织物应答的锌手指) 。幼苗宫外地 overexpressing GAZ (GAZ 公牛) 在 MC 形成期间对骆驼毛的织物和 GA 敏感,而 GAZ-SRDX 和 RNAi 幼苗显示了相反的显型。另外,我们的结果显示 GAZ 涉及骆驼毛的织物和 GA 动态平衡的 transcriptional 规定。与那件骆驼毛的织物和 GA 协调控制预定 MC 形成的以前的研究一致,我们也证实了在骆驼毛的织物和 GA 之间的唯一的相互影响并且识别了在 Arabidopsis 根的 GT 成熟期间衔接二条荷尔蒙小径的因素和规章的网络。 | Shin Ae Lee Sejeong Jang Eun Kyung Yoon Jung-Ok Heo Kwang Suk Chang Ji Won Choi Souvik Dhar Gyuree Kim Jeong-Eun Choe Jae Bok Heo Chian Kwon Jae-Heung Ko Yong-Sic Hwang Jun Lim | 2016 | Molecular Plant2016，9，6： | 2 |
| 7 | How Can We Predict the Presence of Missed Synchronous Lesions After Endoscopic Submucosal Dissection for Early Gastric Cancers or Gastric Adenomas?显示文摘 | Jun Hwan Yoo Sung Jae Shin Kee Myung Lee Jae Myoung Choi Jeong Ook Wi Dong Hoon Kim Sun Gyo Lim Jae Chul Hwang Jae Youn Cheong Byung Moo Yoo Kwang Jae Lee Jin Hong Kim Sung Won Cho | 2013 | Journal of Clinical Gastroenterology2013，，2： | 2 |
| 8 | Percutaneous radiofrequency ablation for early-stage hepatocellular carcinoma as a first-line treatment: long-term results and prognostic factors in a large single-institution series显示文摘 | Dongil Choi Hyo K. Lim Hyunchul Rhim Young-sun Kim Won Jae Lee Seung Woon Paik Kwang Cheol Koh Joon Hyoek Lee Moon Seok Choi Byung Chul Yoo | 2007 | European Radiology2007，，3： | 2 |
| 9 | Reappraisal of serum alpha‐foetoprotein as a surveillance test for hepatocellular carcinoma during entecavir treatment显示文摘 | Gi‐Ae Kim Chang Hyeon Seock Jang Won Park Jihyun An Kwang‐Sun Lee Jee Eun Yang Young‐Suk Lim Kang Mo Kim Ju Hyun Shim Danbi Lee Han Chu Lee | 2015 | Liver Int2015，，1： | 2 |
| 10 | Strategic joint ventures with developing country in battles for technical standards 显示文摘 | Sang Chae Choi Kwang Sun Lim Pyung H Yu | 1999 | Japan and the Word Economy1999，，11： | 1 |
| 11 | Risk factors for perforations associated with endoscopic submucosal dissection in gastric lesions: emphasis on perforation type显示文摘 | Jun Hwan Yoo Sung Jae Shin Kee Myung Lee Jae Myoung Choi Jeong Ook Wi Dong Hoon Kim Sun Gyo Lim Jae Chul Hwang Jae Youn Cheong Byung Moo Yoo Kwang Jae Lee Jin Hong Kim Sung Won Cho | 2012 | Surgical Endoscopy2012，，9： | 1 |
| 12 | Relationship Between Visceral Adiposity and Bone Mineral Density in Korean Adults显示文摘 | Han Seok Choi Kwang Joon Kim Kyoung Min Kim Nam Wook Hur Yumie Rhee Dae Suk Han Eun Jig Lee Sung-Kil Lim | 2010 | Calcified Tissue International2010，，3： | 1 |
| 13 | Efficacy of Entecavir and Adefovir Combination Therapy for Patients with Lamivudine- and Entecavir-Resistant Chronic Hepatitis B显示文摘 | Jung Jeon Hyun Shin Joung Lee Kwang Joo Jae Cha Jae Park Jun Lim Kyuseong Lim Sunyong Kim | 2012 | Digestive Diseases and Sciences2012，，5： | 1 |
| 14 | Corticotropin-releasing hormone downregulates IL-10 production by adaptive forkhead box protein 3–negative regulatory T cells in patients with atopic dermatitis显示文摘 | Sang Ho Oh Chang Ook Park Wen Hao Wu Ji Young Kim Shan Jin Dashlkhumbe Byamba Byung Gi Bae Seongmin Noh Beom Jin Lim Ji Yeon Noh Kwang Hoon Lee | 2011 | The Journal of Allergy and Clinical Immunology2011，，1： | 1 |
| 15 | Clinical Useful- ness of Serum Cystatin C as a Marker of Renal Function 显示文摘 | Kwang Sook Woo Jae Lim CHoi Bo Ram Kim | 2014 | 38:278-2842014，38，： | 1 |
| 16 | Strategic joint ventures with developing country in battles for technical standards 显示文摘 | Sang Chae Choi Kwang Sun Lim Pyung Ⅱ Yu | 1999 | Japan and the World Economy1999，，11： | 1 |
| 17 | Modulation of Adiponectin as a Potential Therapeutic Strategy显示文摘 | Soo Lim Michael J. Quon Kwang Kon Koh | 2014 | Atherosclerosis2014，，： | 1 |
| 18 | Definitive chemoradiation therapy with capecitabine in locally advanced pancreatic cancer显示文摘 | Hyo Song Kim Seong Yoon Yi Hyun Jung Jun Jeeyun Lee Se Hoon Park Jong Kyun Lee Kyu Taek Lee Kwang Hyuck Lee Dong Wook Choi Seong-Ho Choi Jin Seok Heo Young Suk Park Ho Yeong Lim Won Ki Kang Hee Chul Park Do Hoon Lim Joon Oh Park | 2010 | Anti-Cancer Drugs2010，，1： | 1 |
| 19 | Cleaved c-FLIP mediates the antiviral effect of TNF-α against hepatitis B virus by dysregulating hepatocyte nuclear factors显示文摘 | Yong Kwang Park Eun-Sook Park Doo Hyun Kim Sung Hyun Ahn Seung Hwa Park Ah Ram Lee Soree Park Hong Seok Kang Ji-Hyun Lee Jong Man Kim Suk-Koo Lee Keo-Heun Lim Nathalie Isorce Shuping Tong Fabien Zoulim Kyun-Hwan Kim | 2015 | Journal of Hepatology2015，，： | 1 |
| 20 | Clinical parameters predictive of outcomes in sorafenib‐treated patients with advanced hepatocellular carcinoma显示文摘 | Ju‐Yeon Cho Yong‐Han Paik Ho Yeong Lim Young Gon Kim Hyo Keun Lim Yang Won Min Geum‐Youn Gwak Moon Seok Choi Joon Hyeok Lee Kwang Cheol Koh Seung Woon Paik Byung Chul Yoo | 2013 | Liver Int2013，，6： | 1 |
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