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		题名	作者	年代	出处	被引量
	1	Omeprazole decreases magnesium transport across Caco-2 monolayers显示文摘AIM:To elucidate the effect and underlying mechanisms of omeprazole action on Mg 2+ transport across the intestinal epithelium.METHODS:Caco-2 monolayers were cultured in various dose omeprazole-containing media for 14 or 21 d before being inserted into a modified Ussing chamber apparatus to investigate the bi-directional Mg 2+ transport and electrical parameters.Paracellular permeability of the monolayer was also observed by the dilution potential technique and a cation permeability study.An Arrhenius plot was performed to elucidate the activation energy of passive Mg 2+ transport across the Caco-2 monolayers.RESULTS:Both apical to basolateral and basolateral to apical passive Mg 2+ fluxes of omeprazole-treated epithelium were decreased in a dose-and time-dependent manner.Omeprazole also decreased the paracellular cation selectivity and changed the paracellular selective permeability profile of Caco-2 epithelium to Li +,Na +,K +,Rb +,and Cs + from seriesⅦto seriesⅥof the Eisenman sequence.The Arrhenius plot revealed the higher activation energy for passive Mg 2+ transport in omeprazoletreated epithelium than that of control epithelium,indicating that omeprazole affected the paracellular channel of Caco-2 epithelium in such a way that Mg 2+ movement was impeded.CONCLUSION:Omeprazole decreased paracellular cation permeability and increased the activation energy for passive Mg 2+ transport of Caco-2 monolayers that led to the suppression of passive Mg 2+ absorption.	Narongrit Thongon Nateetip Krishnamra	2011	World Journal of Gastroenterology2011，17，12：	4
	2	Claudin expression in the bone-lining cells of female rats exposed to long-standing acidemia显示文摘	Wongdee K Riengrojpitak S Krishnamra N	2010	Exp Mol Pathol2010，88，2：	1
	3	Anxiolytic-like actions of reboxetine, venlafaxine and en- durance swimming in stressed male rats 显示文摘	Lapmanee S Charoenphandhu N Krishnamra N	2012	Behavioural Brain Research2012，231，1：	1
	4	Biomagnetic of Apatite-Coated Cobalt Ferrite: A Core–Shell Particle for Protein Adsorption and pH-Controlled Release显示文摘	I-Ming Tang Nateetip Krishnamra Narattaphol Charoenphandhu Rassmidara Hoonsawat Weeraphat Pon-On	2010	Nanoscale Research Letters2010，，1：	1
	5	In vitro study of vancomycin release and osteoblast-like cell growth on structured calcium phosphate-collagen显示文摘	Weeraphat Pon-On Narattaphol Charoenphandhu Jarinthorn Teerapornpuntakit Jirawan Thongbunchoo Nateetip Krishnamra I-Ming Tang	2012	Materials Science & Engineering C2012，，：	1
	6	Evidence for di- rect effects of prolaetin on human osteoblasts: inhibition of cell growth and mineralization 显示文摘	Seriwatanachai D Krishnamra N van Leeuwen JPTM	2009	Journal of Cellular Biochemistry2009，107，4：	1
	7	Site- specific regulation of ion transport by prolactin in rat colon epithelium显示文摘	Deachapunya C Poonyachoti S Krishnamra N	2012	Am J Physiol Gastrointest Liver Physiol2012，302，10：	1

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