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274篇 您的检索式:作者名="Krause DS"
    题名 作者 年代 出处 被引量
1癌症治疗的靶点——酪氨酸激酶显示文摘蛋白酪氨酸激酶家族(TKs)催化磷酸从ATP转移至多肽链酪氨酸残基上.人类基因组包括了90个TK和43个类似TK的基因,这些基因的产物调节细胞的增生、存活、分化、功能和运动.早在25年前,在逆转录病毒诱导产生的动物肿瘤中,就认为TKs可能是癌基因.然而,因为仅有极少的证据说明其在人类癌症中发挥始动作用,并且考虑到药物的特异性和毒性,所以在开发癌症治疗药物时被忽视了.但随着TK融合蛋白BCR-ABL抑制剂甲磺酸伊马替尼(imatinib mesylate,商品名为格列卫)在慢性粒细胞白血病(CML)中的成功应用,TKs的前景发生了根本的改变.现在认为TKs是癌症化疗很好的靶点.本文综述了TKs靶向治疗癌症的情况,并探讨了其面临的挑战和将来的发展前景.Krause DS Van Etten RA 黄艳 2005中国处方药2005,,10:45
2Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz 2006Cytotherapy2006,,4:11
3Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz 2006Cytotherapy2006,,4:9
4Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement显示文摘EM Horwitz K Le Blanc M Dominici I Mueller I Slaper-Cortenbach FC Marini RJ Deans DS Krause A Keating 2005Cytotherapy2005,,5:2
5Multi-organ, multi-lineage engraftment by a single bone marrow- derived stem cell显示文摘Krause DS Theise ND Collector MI 2001Cell2001,105,3:1
6Multi -organ,multi-lineage engraftment by a single bone marrow-derived stem cell显示文摘Krause DS Theise ND Collector MI 2001Cell2001,105,3:1
7Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell显示文摘 Theise ND Collector MI 2001Cell2001,105,3:1
8PLasticity of marrow-derived stem cells 显示文摘Krause DS 2002Gene Therapy2002,9,:1
9Multi-organ,multi-lineage engraftment by a single bone marrow-derived stem cell显示文摘Krause DS Theise ND Collector MI 2001Cell2001,105,3:1
10Multi-Organ,Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell显示文摘Krause DS Theise ND Collector MI 0,,:1
11Flow Cytometry for Hematopoietic Cells显示文摘Krause DS Delelys ME Preffer FI 2014Methods in Molecular Biology2014,,1109:1
12Plasticity of bone marrow-derived stem cells显示文摘Grove JE Bruscia E Krause DS 2004Stem Cells2004,22,4:1
13Plasticity of bone marrow-derived stem cells显示文摘Grove JE Bruscia E Krause DS 2009Stem Cells2009,22,4:1
14Multi-organ,multi-lirieage engraftment by a single bone marrow-derived stem cell显示文摘Krause DS Theise ND Collector MI 2001Cell2001,105,3:1
15Toward a new paradigm of cell plasticity显示文摘Theise ND Krause DS 2002Leukemia2002,16,4:1
16A randomized doub- le blind trial of anidulafizngin versus fluconazole for the treat- ment of esophageal candidiasis 显示文摘Krause DS Smjeeae AE van Rensburg C 2004Clin Infect Dis2004,39,6:1
17Engraftment of bonemarrow-derived epithelial cells 显示文摘Krause DS 2005AnnNYAcadSci2005,1044,:1
18Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz 2006Cytotherapy2006,,4:1
19Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell 显示文摘Krause DS Theise ND Collector MI 2001Cell2001,105,3:1
20Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell 显示文摘Krause DS Theise ND Collector MI 2001Cell2001,105,3:1
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