|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A Comparative Study on the Role of Cytokinins in Caryopsis Development in the Maize miniature1 Seed Mutant and Its Wild Type显示文摘We report here on a comparative developmental profile of plant hormone cytokinins in relation to cell size,cell number and endoreduplication in developing maize caryopsis of a cell wall invertase-deficient miniature1(mn1) seed mutant and its wild type,Mn1,genotype.Both genotypes showed extremely high levels of total cytokinins during the very early stages of development,followed by a marked and genotype specific reduction.While the decrease of cytokinins in Mn1 was associated with their deactivation by 9-glucosylation,the absolute and the relative part of active cytokinin forms was higher in the mutant.During the exponential growth phase of endosperm between 6 d after pollination and 9 d after pollination,the mean cell doubling time,the absolute growth rate and the level of endoreduplication were similar in the two genotypes.However,the entire duration of growth was longer in Mn1 compared with mn1,resulting in a significantly higher cell number in the Mn1 endosperm.These data correlate with the previously reported peak levels of the Mn1-encoded cell wall invertase-2(INCW2) at 12 d after pollination in the Mn1 endosperm.A model showing possible crosstalk among cytokinins,cell cycle and cell wall invertase as causal to increased cell number and sink strength of the Mn1 developing endosperm is discussed. | Tomaz Rijavec Maja Kova Ale Kladnik Prem S.Chourey Marina Dermastia | 2009 | Journal of Integrative Plant Biology2009,51,9: | 7 |
| 2 | Is Helicobacter pylori infection a risk factor for disease severity in systemic sclerosis?显示文摘 | Mislav Radi? Du?anka Martinovi? Kaliterna Damir Bonacin Jadranka Morovi? Vergles Josipa Radi? Damir Fabijani? Vedran Kova?i? | 2013 | Rheumatology International2013,,11: | 3 |
| 3 | Regulated upon activation,normal T cell expressed and secreted(RANTES)levels in the peripheral blood of patients with Alzheimer’s disease显示文摘Alzheimer’s disease(AD)is the most common type of dementia,but it is very difficult to diagnose with certainty,so many AD studies have attempted to find early and relevant diagnostic markers.Regulated upon activation,normal T cell expressed and secreted(RANTES,also known as C-C chemokine ligand)is a chemokine involved in the migration of T cells and other lymphoid cells.Changes in RANTES levels and its expression in blood or in cerebrospinal fluid have been reported in some neurodegenerative diseases,such as Parkinson’s disease and multiple sclerosis,but also in metabolic diseases in which inflammation plays a role.The aim of this observational study was to assess RANTES levels in peripheral blood as clinical indicators of AD.Plasma levels of RANTES were investigated in 85 AD patients in a relatively early phase of AD(median 8.5 months after diagnosis;39 men and 46 women;average age 75.7 years),and in 78 control subjects(24 men and 54 women;average age 66 years).We found much higher plasma levels of RANTES in AD patients compared to controls.A negative correlation of RANTES levels with age,disease duration,Fazekas scale score,and the medial temporal lobe atrophy(MTA)score(Scheltens’s scale)was found in AD patients,i.e.,the higher levels corresponded to earlier stages of the disease.Plasma RANTES levels were not correlated with cognitive scores.In AD patients,RANTES levels were positively correlated with the levels of pro-inflammatory cytokines interleukin-6 and tumor necrosis factor-α,which is consistent with the wellknown fact that AD is associated with inflammatory processes.RANTES levels were also positively correlated with insulin levels in AD patients,with insulin resistance(HOMA-R)and pancreatic beta cell function(HOMA-F).This study evaluated several clinical and metabolic factors that may affect plasma levels of RANTES,but these factors could not explain the increases in RANTES levels observed in AD patients.Plasma levels of RANTES appear to be an interesting peripheral marker for early stages of AD.The study was approved by the Ethics Committee of Institute of Endocrinology,Prague,Czech Republic on July 22,2011. | Gabriela Vacínová Daniela Vejražkova Robert Rusina Iva Holmerová Hana Vaňková Eva Jarolímová Josef Včelák Běla Bendlová Markéta Vaňková | 2021 | Neural Regeneration Research2021,16,4: | 3 |
| 4 | Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy显示文摘 | Bernard A. Fang ?aklina Kova?evi? Kyung Chan Park Danuta S. Kalinowski Patric J. Jansson Darius J.R. Lane Sumit Sahni Des R. Richardson | 2014 | BBA - Reviews on Cancer2014,,1: | 2 |
| 5 | Prevention and treatment of postoperative nausea and vomiting显示文摘 | Kova AL | 2000 | Drugs2000,59,2: | 1 |
| 6 | Effect of the mixing conditions on the phase structure of PP/PS blends显示文摘 | Fortelnyi Michal Kova D Mikesova J | 2000 | J Appl Polym Sci2000,59,: | 1 |
| 7 | In- formative value of the VCS parameters of peripheral blood neutrophils in the evaluation of status of pa- tients with recurrent and metastatic cervical cancer 显示文摘 | Gus'kova NK Nerodo GA Levchenko NE | 2010 | Klin Lab Diagn2010,,3: | 1 |
| 8 | Transient alcohol craving suppression by rTMS of dorsal anterior cingulate: an fMRI and LORETA EEG study显示文摘 | De Ridder D Vanneste S Kovaes S | 2011 | Neurosci Lett2011,496,: | 1 |
| 9 | Clinical Opinion: Guidelines for Hysterectomy显示文摘 | Kovae S R | 2004 | Am J Obstet Gynecol2004,191,2: | 1 |
| 10 | Lysophosphatidic acid in ovarian cancer patients显示文摘 | Sedlákova I Vávrová J Tosner J | 2006 | Ceska Cynekol2006,71,4: | 1 |
| 11 | Minimization of zygomatic complex fracture treatment显示文摘 | Kovaes A F Ghahremani M | 2001 | Int J Oral Maxillofac Surg2001,30,5: | 1 |
| 12 | The Nature of the Maeromoleeular Network Structure of Bituminous Coals 显示文摘 | Larsen J Green T Kovae J | 1985 | The Journal of Organic Chemistry1985,50,24: | 1 |
| 13 | Cultures of hESM human embryonic stem cells: Chromosomal aberrations and karyotype stability显示文摘 | M. A. Prokhorovich M. A. Lagar'kova A. G. Shilov T. V. Karamysheva S. L. Kiselyov N. B. Rubtsov | 2007 | Bulletin of Experimental Biology and Medicine2007,,1: | 1 |
| 14 | External influence on magnetic properties of Febased nanocrystalline alloys 显示文摘 | Jozef Sitek Jarmila Degmova' Katarinna Sedlac kova | 2006 | Journal of Magnetism and Magnetic Materials2006,304,: | 1 |
| 15 | Released ATP is an extracellular cytotoxic mediator in salivary histatin5-induced killing of Candida albicans 显示文摘 | KOSHLU KOVA SE ARANJO MV BAEV D | 2000 | Infect Immun2000,68,: | 1 |
| 16 | Role of p38alpha MAPK incardiac apoptosis and remodeling after myocardial infarction 显示文摘 | Ren J Zhang S Kovaes A | 2005 | J Mol Cell Cardiol2005,38,4: | 1 |
| 17 | Molecular analysis of the acetolactate synthase gene of Chlamy domonas reinhardtii and development of a genetically engineered gene asa dominant selectable marker for genetic transformation显示文摘 | KOVA JL ZHANG J FUNKE RP | 2002 | Plant J2002,29,1: | 1 |
| 18 | Pos toperat ivee ompl icat ie ns and mortal i ty associated with operative delay in olderpatlents who have tracture of the hip显示文摘 | Zuekerman JD Skovron ML Kova! KJ | 2009 | Bone Joint Surg2009,73,23: | 1 |
| 19 | Pituitary hyperplasia显示文摘 | Horvath E Kovas K Scheithauer BW | | 0,,3: | 1 |
| 20 | Piezosurgery in oral and maxillofacial surgery显示文摘 | Pavl kova G Foha n R I-Iorka M Hanzelka T Borunska H Sedy J | 2011 | Int J Oral Max-illofac Surg2011,40,: | 1 |