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| 1 | Proteomic analysis of gastric cancer and immunoblot validation of potential biomarkers显示文摘AIM:To search or and validate di erentially expressed proteins in patients with gastric adenocarcinoma.METHODS:We used two-dimensional gel electrophoresis and mass spectrometry to search or di erentially expressed proteins in patients with gastric adenocarcinoma.A set o proteins was validated with immunoblotting.RESULTS:We identified 30 di erent proteins involved in various biological processes:metabolism,development,death,response to stress,cell cycle,cell communication,transport,and cell motility.Eight proteins were chosen or urther validation by immunoblotting.Our results show that gastrokine-1,39S ribosomal protein L12(mitochondrial precursor),plasma cell-induced resident endoplasmic reticulum protein,and glutathione S-trans erase mu 3 were signi icantly underexpressed in gastric adenocarcinoma relative to adjacent non-tumor tissue samples.On the other hand,septin-2,ubiquitin-conjugating enzyme E2 N,and transaldolase were significantly overexpressed.Translationally controlled tumor protein was shown to be di erentially expressed only in patients with cancer o the gastric cardia/esophageal border.CONCLUSION:This work presents a set o possible diagnostic biomarkers,validated or the first time.It might contribute to the e orts o understanding gastric cancer carcinogenesis. | Nina Kocevar Federico Odreman Alessandro Vindigni Snjezana Frkovic Grazio Radovan Komel | 2012 | World Journal of Gastroenterology2012，18，11： | 3 |
| 2 | Influence of some environmental factors on Rhizopus nigricans submerged growth in the form of pellets显示文摘 | Znidarsic P Komel R Pavko A | 2004 | World Journal of Microbiology and Biotechnology2004，16，7： | 1 |
| 3 | A region of proximal learning model of study time allocation 显示文摘 | Janet Metealfe Nate Komell | 2005 | Journal of Memory and Language2005，，52： | 1 |
| 4 | A Mechanistic Model of Cutting Forces in Micro-End-Milling with Cutting-Condition-Independent Cutting Force Coefficients 显示文摘 | Han U1 L Dong-Woo C Komel F E | 2008 | ASME J Manuf Sci Eng (S1087-1357)2008，130，3： | 1 |
| 5 | A novel approach for biohydrogen production显示文摘 | Kovacs Komel L Gergely Maroti Gabor Rakhely | 2006 | International Journal of Hydrogen Energy2006，31，： | 1 |
| 6 | Expression of catalytic subunit of bovine enterokinase in the filamentous fungus Aspergillus niger显示文摘 | Svetina M Krasevec N Komel R | 2000 | J Biotechnol2000，76，23： | 1 |
| 7 | Sequence variations in the osteopretegerin gene promoter in patients with post- menopauzal osteoporesis显示文摘 | Arko B Prezelj J Komel R | 2002 | J Clin Endocrinol Metab2002，87，： | 1 |
| 8 | Association of vitamin D receptor gene polymorphism with bone mineral density in Slovenian postmenopausal women显示文摘 | Marc J Prezeli J Komel R | 2000 | Gynecol Endoerinot2000，14，1： | 1 |
| 9 | Glioma and glioblastoma ? how much do we (not) know? (Review)显示文摘 | Ivana Jov?evska Nina Ko?evar Radovan Komel | 2013 | Molecular and Clinical Oncology2013，，6： | 1 |
| 10 | VDR genotype and response to etidronate therapy in late postmenopausal women显示文摘 | Marc J Prezelj J Komel R | 1999 | Osteoporos Intl1999，10，： | 1 |
| 11 | Effect of immobilization on the stability ofClaviceps purpurea protoplasts显示文摘 | R. Komel D. Rozman A. Puc H. So?i? | 1985 | Applied Microbiology and Biotechnology1985，，2： | 1 |
| 12 | The GAL induction response in yeasts with impaired galactokinase Gallp activity 显示文摘 | Stagoj M Komel R | 2008 | World Journal of Microbiology and Biotechnology2008，24，10： | 1 |
| 13 | Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis 显示文摘 | Prezelj J Komel R | 2002 | J Clin Endocrinol Metab2002，87，9： | 1 |
| 14 | Intraspinal schwannoma presenting solely with rectal pain 显示文摘 | Komel E E Vlahakos D | 1988 | Neurosurgery1988，22，： | 1 |
| 15 | Automatic lexeme acquisition for a multilingual medical subword thesaurus 显示文摘 | Komel Marko etc | 2007 | International Journal of Medical Informatics2007，，23： | 1 |
| 16 | Photocatalytic degradationwith immobilised Ti02 of three selected neonicotinoidinsecticides : imidacloprid, thiamethoxam and clothianidin 显示文摘 | 之abar R Komel T Fabjan J | 2012 | Chemosphere2012，89，3： | 1 |
| 17 | Association of vitamin D receptor gene polymorphism with bone mineral density in slovenian postmenopausal women显示文摘 | Marc J Preze J Komel R | 2000 | Gynecol Endocrinol2000，14，1： | 1 |
| 18 | Proteomic approaches in biomark- er discovery: New perspectives in cancer diagnostics 显示文摘 | Hudler P Koeevar N Komel R | 2014 | Sci World J2014，2014，26： | 1 |
| 19 | Tool embedded thin film microsensors for monitoring thermal phenomena at tool-workpiece interface during machining显示文摘 | Dirk Werschmoeller Komel Ehmann Xiaochun Li | | 0，，02： | 1 |
| 20 | An Adaptive NeuroFuzzy Inference System for estimating the number of vehicles for queue management at signalized intersections显示文摘 | Komel M Ata M K Mojtaba A | | 0，，： | 1 |
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