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| 1 | Adsorption of basic dye (methylene blue)onto activated carbon prepared from rattan saw dust显示文摘 | Hameed BH Ahmad AL Latiff KNA | | 0，，01： | 1 |
| 2 | Antioxidant mechanism of hepatoprotection by ursodeoxycholic acid in exoerimental alcoholic steatohepatitis显示文摘 | LUKIVSKAYA O ZAVODNIK L KNAS M | 2006 | Adv Med Sci2006，51，： | 1 |
| 3 | Quantitative trait locus effects and environment a Iinteraction in a sample of North a- merican barley germ plasm显示文摘 | Hayes P M Liu B H Kna P S | 1993 | Theoretical and Applied Genetics1993，87，： | 1 |
| 4 | The twenty-degree reverse-trendelenburg position decreases the incidence and severity of postoperative nausea and vomiting after thyroid surgery显示文摘 | Tominaga KNA Kahara O | | 0，，05： | 1 |
| 5 | Phenotypic and functional reversal within the early human hematopoietic compartment显示文摘 | KNA(A)N-SHANZER S VAN DER VELDE-VAN DIJKE I VAN DE WATERING MJ | 2008 | Stem Cells2008，26，12： | 1 |
| 6 | Matrix metalloproteinases in- arthritic disease显示文摘 | Murphy G Kna upcr ~ Atkinson S | 2002 | Arthritis Res2002，4，： | 1 |
| 7 | APACHE II: a severity of disease classification sys-tem显示文摘 | Knas WA | 2000 | Crit Care Med2000，13，： | 1 |
| 8 | Barriers in contribution of human mesenchymal stem cells to murine muscle regeneration显示文摘AIM: To study regeneration of damaged human and murine muscle implants and the contribution of added xenogeneic mesenchymal stem cells(MSCs).METHODS: Minced human or mouse skeletal muscle tissues were implanted together with human or mouse MSCs subcutaneously on the back of non-obese diabetic/severe combined immunodeficient mice. The muscle tissues(both human and murine) were minced with scalpels into small pieces(< 1 mm3) and aliquoted in portions of 200 mm3. These portions were either cryopreserved in 10% dimethylsulfoxide or freshly implanted. Syngeneic or xenogeneic MSCs were added to the minced muscles directly before implantation. Implants were collected at 7, 14, 30 or 45 d after transplantation and processed for(immuno)histological analysis. The progression of muscle regeneration was assessed using a standard histological staining(hematoxylin-phloxinsaffron). Antibodies recognizing Pax7 and von Willebrand factor were used to detect the presence of satellite cells and blood vessels, respectively. To enable detection of the bone marrow-derived MSCs or their derivatives we used MSCs previously transduced with lentiviral vectors expressing a cytoplasmic LacZ gene. X-gal staining of the fixed tissues was used to detect β-galactosidase-positive cells and myofibers.RESULTS: Myoregeneration in implants of fresh murine muscle was evident as early as day 7, and progressed with time to occupy 50% to 70% of the implants. Regeneration of fresh human muscle was slower. These observations of fresh muscle implants were in contrast to the regeneration of cryopreserved murine muscle that proceeded similarly to that of fresh tissue except for day 45(P < 0.05). Cryopreserved human muscle showed minimal regeneration, suggesting that the freezing procedure was detrimental to human satellite cells. In fresh and cryopreserved mouse muscle supplemented with LacZ-tagged mouse MSCs, β-galactosidase-positive myofibers were identified early after grafting at the wellvascularized periphery of the implants. The contribution of human MSCs to murine myofiber formation was, however, restricted to the cryopreserved mouse muscle implants. This suggests that fresh murine muscle tissue provides a suboptimal environment for maintenance of human MSCs. A detailed analysis of the histological sections of the various muscle implants revealed the presence of cellular structures with a deviating morphology. Additional stainings with alizarin red and alcian blue showed myofiber calcification in 50 of 66 human muscle implants, and encapsulated cartilage in 10 of 81 of murine muscle implants, respectively.CONCLUSION: In mouse models the engagement of human MSCs in myoregeneration might be underestimated. Furthermore, our model permits the dissection of speciesspecific factors in the microenvironment. | Anabel S de la Garza-Rodea Hester Boersma Cheryl Dambrot Antoine AF de Vries Dirk W van Bekkum Shoshan Kna?n-Shanzer | 2015 | World Journal of Experimental Medicine2015，5，2： | 1 |
| 9 | Sahvary innate defense system in type 1 diabetes mellitus in children with mixed and permanent dentition 显示文摘 | ZaIewska A Knas M Kuzmiuk A | 2013 | Acta Odontol Scand2013，71，6： | 1 |
| 10 | A- PACHE II :a severity of disease classification system 显示文摘 | KNAS WA DRAPER EA WAGNER DP | 2000 | Crit Care Med2000，13，10： | 1 |
| 11 | Exploring the spatial pattern ofmental health expenditure 显示文摘 | Moscone F Kna PPM | 2005 | Ment Health policy Econ2005，8，4： | 1 |
| 12 | Endowing human adenovirus serotype 5 vectors with fiber domains of species B greatly enhances gene transfer into human mesenchymal stem cells显示文摘 | Kna an-Shanzer S van de Watering MJ van der Velde I | 2005 | Stem Cells2005，23，10： | 1 |
| 13 | Diabetes mellitus-related oxidative stress and its parameters in saliva 显示文摘 | Bolesta D Hoscilowicz PD Knas M | 2013 | Pol Merkur Lekarski2013，35，209： | 1 |
| 14 | Pres- sure ulcers: Description of a new model and use of mesenchymal stem ceils for repair显示文摘 | dela Garza- Rodea AS Kna/in- Shanzer S van Bekkum DW | 2011 | Dermatology2011，223，3： | 1 |
| 15 | Antioxidant mechanism of hepatoprotection by ursodeoxycholic acid 717 in experimental alcoholic steatohepatitis 显示文摘 | Lukivskaya O Zavodnik L Knas M | 2006 | Adv Med Sci2006，51，： | 1 |
| 16 | Antioxidant mechanism of hepatoprotection by ursodeoxycholic acid in experimental alcoholic steatohepatitis显示文摘 | Lukivskaya O Zavodnik L Knas M | 2006 | Adv Med Sci2006，51，： | 1 |
| 17 | Cell cycle state,response to hemopoietic growth factors and retroviral vector-mediated transduction of human hemopoietic stem cells显示文摘 | Kna?n-Shanzer S Valerio D van Beusechem VW | | 0，，04： | 1 |
| 18 | Differentiation ofprostatitis and prostate cancer by using diffusion weighted MRimaging and MR-guided biopsy at 3 T显示文摘 | Nagel KNA Schouten MG Hambrock T | 2013 | Radiology2013，267，： | 1 |
| 19 | Preparation, X-ray, derivatographic and infared study of goethites 显示文摘 | KNAS K SOLYMAR K | 1970 | Acat Chim Acad Sci Hung1970，66，： | 1 |
| 20 | Bone remodeling character- istics of a short-stemmed total hip replacement 显示文摘 | Hsiang HC Bernard F Morrey KNA | 2009 | J Arthroplasty2009，6，： | 1 |
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