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| 1 | Endoscopic and Percutaneous Preoperative Biliary Drainage in Patients with Suspected Hilar Cholangiocarcinoma显示文摘 | Jaap J. Kloek Niels A. Gaag Yalda Aziz Erik A. J. Rauws Otto M. Delden Johan S. Lameris Olivier R. C. Busch Dirk J. Gouma Thomas M. Gulik | 2010 | Journal of Gastrointestinal Surgery2010，，1： | 3 |
| 2 | Differentiation of malignant and benign proximal bile duct strictures: The diagnostic dilemma显示文摘AIM: To identify the criteria for the differentiation of hilar cholangiocarcinoma (HCCA) from benign strictures. METHODS: A total of 68 patients underwent resection of lesions suspicious for HCCA between 1998 and 2006. The results of laboratory investigations, imaging studies and brush cytology were collected. These fi ndings were analyzed to obtain the fi nal diagnosis. RESULTS: Histological examination of the resected specimens confirmed HCCA in 58 patients (85%, group Ⅰ) whereas 10 patients (15%, groupⅡ) were diagnosed to have benign strictures. The most common presenting symptom was obstructive jaundice in 77% patients (79% group Ⅰvs 60% group Ⅱ P = 0.23). Laboratory findings showed greater elevation of transaminase levels in group Ⅰcompared to group Ⅱ The various imaging modalities showed vascular involvement exclusively in the malignant group (36%,P < 0.05). Brush cytology was positive for malignant cells in only 50% patients in group Ⅰ whereas none in group Ⅱ showed malignant cells. CONCLUSION: Despite improvements in imaging techniques, 10 patients (15%) with a presumptive diagnosis of HCCA were ultimately found to have benign strictures. Except for vascular involvement which was associated significantly with malignancy, there were no conclusive features of malignancy on regular imaging modalities. This uncertainty should be taken into account when patients with a suspicious lesion at the liver hilum are considered for resection. | Jaap Jacob Kloek Otto Marinus van Delden Deha Erdogan Fibo Jan ten Kate Erik Anthoni Rauws Olivier Robert Busch Dirk Joan Gouma Thomas Mathijs van Gulik | 2008 | World Journal of Gastroenterology2008，14，32： | 2 |
| 3 | Regulation of Jakkinases by intracellular leptin receptor sequences 显示文摘 | Kloek C Haq AK Dunn SL | 2002 | JBiol Chem2002，277，41： | 1 |
| 4 | Scheduling for deficit irrigation-crop yield predictor显示文摘 | Kloeke NL Stone LR Briggeman S | 2010 | Applied Engineering in Agri- culture2010，26，3： | 1 |
| 5 | Hydrolyzed Casein Decreases Postprandial Glucose Concentrations in T2DM Patients Irrespective of Leucine Content显示文摘 | Bart F. Geerts Marloes G.J. van Dongen Baukje Flameling Matthijs M. Moerland Marieke L. de Kam Adam F. Cohen Johannes A. Romijn Cindy C. Gerhardt Joris Kloek Jacobus Burggraaf | 2011 | Journal of Dietary Supplements2011，，3： | 1 |
| 6 | Technological and economical com- parison of roughing strategies via milling, sinking-EDM, wire-EDM and ECM for titanium- and nickel-based hlisks显示文摘 | Kloeke F Zeis M Klink A | 2013 | CIRP Journal of Manufacturing Science and Technology2013，6，3： | 1 |
| 7 | ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging- executive summary: areport of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines(ACC/AHA/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Cardiac Radionuclide Imaging) 显示文摘 | Kloeke FJ Baird MG Lorell BH | 2003 | Circulation2003，108，11： | 1 |
| 8 | IPP-rich milk protein hydrolysate lowers blood pressure in subjects with stage 1 hypertension, a randomized controlled trial显示文摘 | BOELSMA E KLOEK J | 2010 | Nutr J2010，9，： | 1 |
| 9 | Process Evaluation of a Dutch Community Intervention to improve Health Related Behaviour in deprived neighbourhoods 显示文摘 | Kloek GC van Lenthe FJ Meertens YMG | 2006 | Soz Praventiv Med2006，51，： | 1 |
| 10 | Embolization for hemoptysis in chronic thromboembolic pulmonary hypertension:report of two cases and a review of the literature显示文摘 | Reesink HJ van Delden OM Kloek JJ | | 0，，01： | 1 |
| 11 | Characteristics of traumatic cataract wound dehiscence 显示文摘 | Kloek CE Andreoli MT Andreoli CM | 2011 | Am J Ophthalmol2011，152，2： | 1 |
| 12 | Enueleation of open globe injury显示文摘 | Savar A Andreoli MT Kloek CE | 2009 | Am J Ophtahalmo12009，147，： | 1 |
| 13 | Stock selection, style rotation, and risk显示文摘 | Lucas A Van Dijk R Kloek T | 2002 | Journal of Empirical Finance2002，9，： | 1 |
| 14 | Surveillance and epidemiology of surgical site infections after cardiothoracic surgery in The Netherlands, 2002-2007显示文摘 | Mannien J Wille JC Kloek J J | 2011 | J Thorac Cardiovasc Surg2011，141，： | 1 |
| 15 | IPP-rich milk protein hydrolysate lowers blood pressure in subjects with stage 1 hypertension,a randomized controlled trial显示文摘 | Boelsma E Kloek J | 2010 | Nutr J2010，，9： | 1 |
| 16 | Low rate of endophthalmitis in a large series of open globe injuries显示文摘 | Andreoli CM Andreoli MT Kloek CE | 2009 | Am J Ophthalmol2009，147，4： | 1 |
| 17 | Prodrugs of 5-aminolevulinic acid for photodynamic therapy显示文摘 | Kloek J Beijersbergen HG | 1996 | Photochem Photobiol1996，64，6： | 1 |
| 18 | Localization and identification of populations of phosphatase-active bacterial cells associated with activated sludge flocs显示文摘 | F V Kloeke G G Geesey | 1999 | Microbial Ecology1999，38，3： | 1 |
| 19 | Derivatives of 5-aminolevulinic acid for photodynamic therapy: enzy- matic conversion into protoporphyrin显示文摘 | Kloek J Akkermans W Beijersbergen HG | 1998 | Photochem Pho-tobiol1998，67，1： | 1 |
| 20 | Preoperative biliary drainage in patients with obstructive jaundice: history and current status显示文摘 | van der Gaag NA Kloek JJ de Castro SM | 2009 | J Gastrointest Surg2009，13，4： | 1 |
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