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36篇 您的检索式:作者名="Klein HH"
    题名 作者 年代 出处 被引量
12型糖尿病患者及其一级亲属和非糖尿病者骨骼肌的胰岛素信号传导显示文摘2型糖尿病与骨骼肌和其他组织的葡萄糖利用能力下降有关。胰岛素抵抗可能与遗传因素和糖尿病本身的代谢异常如高血糖或非脂化脂肪酸(NEFA)升高有关。遗传因素和继发的胰岛素抵抗代谢异常可能是由于调节葡萄糖代谢的胰岛素受体和受体后信号传导的改变引起。胰岛素与其受体结合后,受体自身磷酸化,受体激酶活化,一些细胞间的底物磷酸化,其中在骨骼肌细胞中胰岛素受体底物-1(IRS-1)最重要。酪氨酸磷酸化的IRS与脂肪激酶磷脂酚肌醇3’(PI3’)Meyer MM Levin K Grimmsmann T Beck-Nielsen H Klein HH Diabetologia 叶华 2003中国糖尿病杂志2003,11,2:3
2Oral exposure to inorganic arsenic:evaluation of its carcinogenic and noncarcinogenic effects显示文摘Schuhmacher-Wolz U Dieter HH Klein D 2009Crit Rev Toxicol2009,39,4:1
3Recuurent hypoglycemic episode in a pa-tientwith Type 2 diabetes under fibrate therapy显示文摘KleinJ Klein HH 2002J Dia-betes and itsComplications-2002,,15:1
4Cell death in ischemic reperfused porcine hearts: a histochemical and function study显示文摘Pich S Klein HH Lindert S 1988Asic Res Caroliol1988,83,5:1
5Oral exposure toinorganic arsenic:evaluation of its carcinogenic and non-carcinogen-ic effects显示文摘Schuhmacher-Wolz U Dieter HH Klein D 2009Crit Rev Toxicol2009,39,4:1
6Oral exposure to inorganic arsenic: evaluation of its carcinogenic and non carcino- genic effects显示文摘Schuhmaeher-Wolz U Dieter HH Klein D 2009Crit Rev Toxicol2009,39,4:1
7Myocardial protection by Na^+-H^+ exchange inhibition in ischemic, reperfused porcine hearts显示文摘Klein HH Pich S Bohle RM 1995Circulation1995,92,4:1
8Value of palliative resection in gastric cancer显示文摘Hartgrink HH Putter H Klein Kranenbarg E 2002BrJ Surg2002,89,11:1
9Cell death in ischemic reperfused porcine hearts: a histochemical and function study显示文摘Pich S Klein HH Lindert S 1988Basic Res Cardiol1988,83,5:1
10Outcome after mitral valve repair for acute and healed infective endocarditis显示文摘Feringa HH Bax JJ Klein P 2006Eur J Cardiothorac Surg2006,29,3:1
11Novel adipocyte lines from brown fat:a model system for the study of dif- ferentiation, energy metabolism, and insulin action 显示文摘Klein J Fasshauer M Klein HH 2002Bioessys2002,24,4:1
12Cell death in isehemic reperfused porcine hearts: a histochemical and functional study 显示文摘Pich S Klein HH Lindert S 1988Basic Res Cardiol1988,83,5:1
13Na( + )/H( + ) exchange inhibitor cariporide attenuates cell injury predominantly during ischemia and not at onset of reperfusion in poreine hearts with low residual blood flow 显示文摘Klein HH Pich S Bohle RM 2000Circulation2000,102,16:1
14Na+/H+ exchange inhibitor cariporide attenuates cell injury pmdominantly during ischemia and not at onset of reperfusion in porcine hearts with low residual blood flow显示文摘Klein HH Pich S Bohle RM 2000Circulation2000,102,16:1
15Time - dependent protection by Na^ +/H^+ exchange inhibition in a regionally ischemic, reperfused porcine heart preparation with low residual blood flow显示文摘Klein HH Bohle RM Pich S 1998J Mol Cell Cardiol1998,30,4:1
16Cell death in ischemic reperfused porcine hearts: a histochemical and function study显示文摘Pich S Klein HH Lindert S 1988Asic Res Caroliol1988,83,5:1
17Preserved insulin secretion capacity and graft function of eryostored encapsulated rat islets显示文摘Schneider S Klein HH 0,,1:1
18Calpain inhibition impairs glycogen syntheses in HepG2 hepatoma cells without altering insulin signaling显示文摘Meier M Klein HH Kramer J 0,,:1
19Time - dependent protection by Na+/H+exchange inhibition in a regionally ischemic, reperfused porcine heart preparation with low residual blood flow显示文摘Klein HH Bohle RM Pith S 1998J Mol Cell Cardiol1998,30,4:1
20Outcome after mitral valve repair for acute and healed infective endocarditis显示文摘Feringa HH Bax JJ Klein P 2006Eur J Cardiothorac Surg2006,29,3:1
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