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| 1 | Helicobacter pylori associated chronic gastritis,clinical syndromes,precancerous lesions,and pathogenesis of gastric cancer development显示文摘Helicobacter pylori(H.pylori)infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis(AG),or gastric intestinal metaplasia(GIM),and cancer.Various molecular alterations are identified not only in gastric cancer(GC)but also in precancerous lesions.H.pylori treatment seems to improve AG and GIM,but still remains controversial.In contrast,many studies,including meta-analysis,show that H.pylori eradication reduces GC.Molecular markers detected by genetic and epigenetic alterations related to carcinogenesis reverse following H.pylori eradication.This indicates that these changes may be an important factor in the identification of high risk patients for cancer development.Patients who underwent endoscopic treatment of GC are at high risk for development of metachronous GC.A randomized controlled trial from Japan concluded that prophylactic eradication of H.pylori after endoscopic resection should be used to prevent the development of metachronous GC,but recent retrospective studies did not show the tendency.Patients with precancerous lesions(molecular alterations)that do not reverse after H.pylori treatment,represent the'point of no return'and may be at high risk for the development of GC.Therefore,earlier H.pylori eradication should be considered for preventing GC development prior to the appearance of precancerous lesions. | Jiro Watari Nancy Chen Peter S Amenta Hirokazu Fukui Tadayuki Oshima Toshihiko Tomita Hiroto Miwa Kheng-Jim Lim Kiron M Das | 2014 | World Journal of Gastroenterology2014，20，18： | 60 |
| 2 | Current medical therapy of inflammatory bowel disease显示文摘INTRODUCTIONThe 1990’s have brought a significant promise and the hopefor a better and brighter future in the new millennium forpatients with inflammatory bowel disease(IBD).A betterunderstanding of the pathophysiology of IBD symptoms hasled to newer treatment modalities and streamlining oftherapy for specific subsets of patients. | Kiron M. Das Sherif A. Farag | 2000 | World Journal of Gastroenterology2000，6，4： | 16 |
| 3 | Pathogenesis and clinical spectrum of primary sclerosing cholangitis显示文摘Primary sclerosing cholangitis(PSC) is a disease of the biliary tract, which has been documented in the literature since 1867. This disease has a strong predilection for affecting men and can be seen in individuals as young as 2 years of age. PSC has a strong associated with inflammatory bowel disease, more commonly with ulcerative colitis, and is also part of the clinical spectrum of Ig G4-related diseases. Smallduct PSC, a variant of PSC, also has an association with inflammatory bowel disease. The exact pathogenesis of PSC is not well understood at present, however, is likely a combination of a genetic predisposition with alteration of the molecular structure of the gut. Abnormal serum liver chemistry and presence of certain autoimmune markers are usually the first indicators leading to a diagnosis of PCS, however, these may often be normal in early stages of this disease. The diagnosis is made by cholangiography, which is now considered the gold standard. PSC is a known pre-malignant condition. Such patients have an increased risk of developing cholangiocarcinoma, gallbladder neoplasia, and colon cancer. Many new treatment modalities have emerged in the recent past, including anti-tumor necrosis factor-α and anti-integrins; however, liver transplantation is the only known cure for PSC. Despite past and present research, PSC remains an enigmatic biliary disease with few viable treatment options. | Neelam G Gidwaney Swati Pawa Kiron M Das | 2017 | World Journal of Gastroenterology2017，23，14： | 4 |
| 4 | Expression of Masu Salmon Δ5-Desaturase-Like Gene Elevated EPA and DHA Biosynthesis in Zebrafish显示文摘 | Alimuddin Goro Yoshizaki Viswanath Kiron Shuichi Satoh Toshio Takeuchi | 2007 | Marine Biotechnology2007，，1： | 2 |
| 5 | Immune modulation and expression of cytokine genes in rainbow trout Oncorhynchus mykiss upon probiotic feeding 显示文摘 | Panigrahi A Kiron V Satoh S | 2007 | Developmental & Comparative Immunology2007，31，： | 1 |
| 6 | Amino acid-chelate: a better source of Zn, Mn and Cu for rainbow trout, Oncorhynchus mykiss显示文摘 | Mary Jane S. Apines-Amar Shuichi Satoh Christopher Marlowe A. Caipang Viswanath Kiron Takeshi Watanabe Takashi Aoki | 2004 | Aquaculture2004，，1： | 1 |
| 7 | Epigallocatechin-3-gallate(EGCG)affects the antioxidant and immune defense of the rainbow trout,Oncorhynchus mykiss显示文摘 | Thawonsuwan J Kiron V Satoh S | 2010 | Fish Physiology and Bbiochemistry2010，36，3： | 1 |
| 8 | Inclusion of citric acid and/or amino acid-chelated trace elements in alternate plant protein source diets affects growth and excretion of ni- trogen and phosphorus in red sea bream Pagrus major显示文摘 | Sarker M S A Satoh S Kiron V | 2007 | Aquaculture2007，262，24： | 1 |
| 9 | Supplementation of cit- ric acid and amino acid-chelated trace element to develop environment-friendly feed for red sea bream, Pagrus major 显示文摘 | Sarker S A Satoh S Kiron V | 2005 | Aquaculture2005，248，14： | 1 |
| 10 | Trace minerals in fish nutrition显示文摘 | WATANABE T KIRON V SATOH S | 1997 | Aquaculture1997，151，14： | 1 |
| 11 | Transfer free energies of some ions from water to dimethylsulfoxide-water and urea-water mixtures显示文摘 | Kiron K. Kundu Asim K. Das | 1979 | Journal of Solution Chemistry1979，，4： | 1 |
| 12 | Inclusion of citric acid and/ or amino acid - chelated trace dements in alternate plant protein source diets affects growth and excretion of nitrogen and phosphorus in red sea bream Pagrus major 显示文摘 | ALAM S S SHUICHI S KIRON V | 2007 | Aquaculture2007，262，： | 1 |
| 13 | The Ten-year Single-center Experience With 6-Mercaptopurine in the Treatment of Inflammatory Bowel Disease显示文摘 | Kenneth D Glazier Adam L Palance Louis H Griffel Kiron M Das | 2005 | Journal of Clinical Gastroenterology2005，，1： | 1 |
| 14 | The effect of citric acid supplementation on growth performance, phosphorus absorption and retention in rainbow trout (Oncorhynchus mykiss) fed a low-fishmeal diet显示文摘 | Hernandez A J Satoh S Kiron V | 2013 | Ciencia E Investigacion Agraria2013，40，2： | 1 |
| 15 | The viability of probiotic bacteria as a factor influencing the immune response in rainbow trout oncorhynchus mykiss显示文摘 | Panigrahi A Kiron V Puangkaew J | 2005 | Aquaculture2005，243，： | 1 |
| 16 | Enhancement of innate immunity in rainbow trout ( Oncorhynchus mykiss Walbaum) associated with dietary intake of carotenoids from natural products显示文摘 | E.C. Amar V. Kiron S. Satoh T. Watanabe | 2003 | Fish and Shellfish Immunology2003，，4： | 1 |
| 17 | Availability of supplemental amino acid - chelated trace dements in diets containing tricalcium phosphate and phytate to rainbow trout, Oncorhynchus mykiss显示文摘 | APINES M J S SATOH S KIRON V | 2003 | Aquaculture2003，225，： | 1 |
| 18 | What managers really think about social business 显示文摘 | David Kiron Doug Palmer Anh Nguyen Phillips Nina Kruschwitz | 2012 | MIT Sloan Management Review2012，53，4： | 1 |
| 19 | Trace minerals in fish nutrition显示文摘 | Watanabe T Kiron V Satoh S | 1997 | Aquaculture1997，，5： | 1 |
| 20 | Probiotic bacteria Lacto- bacillus rhamnosus influences the blood profile in rainbow trout On- corhynchus mykiss ( Walbaum ) 显示文摘 | Panigrahi A Kiron V Satoh S | 2010 | Fish Physiol Biochem2010，36，4： | 1 |
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