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8篇 您的检索式:作者名="Kevin Grove"
    题名 作者 年代 出处 被引量
1Preempting the Next Disaster: Catastrophe Insur- ance and the Financialization of Disaster Management 显示文摘Kevin Grove 2012Security Dialogue2012,,4:1
2Linking leader skills, follower attitudes, and contextual variables via an integrated model of charismatic leadership显示文摘Groves Kevin S 2005Journal of Management2005,31,2:1
3An Empirical Study of Leader Ethical Values, Transformational and Transactional Leadership ,and Follower Attitudes toward Corporate Social Re- sponsibility 显示文摘Kevin Groves Michael LaRocca 2011Journal of Business Ethics2011,,103:1
4Linking Linear/Nonlinear Thinking Style Balance and Managerial Ethical Decision-Making显示文摘Kevin Groves Charles Vance Yongsun Paik 2008Journal of Business Ethics2008,,80:1
5Understanding and Measuring Linear-Nonlinear Thinking Style for Enhanced Management Education and Professional Practice显示文摘Vance Charles M Groves Kevin S Paik Yongsun Kindler Herb 2007Academy of Management Learning&Education2007,,6:1
6Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates显示文摘McCurdy Carrie E Bishop Jacalyn M Williams Sarah M Grayson Bernadette E Smith M Susan Friedman Jacob E Grove Kevin L 2009Journal of Clinical Investigation2009,,:1
7The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss显示文摘Secher Anna Jelsing Jacob Baquero Arian F Hecksher-S?rensen Jacob Cowley Michael A Dalb?ge Louise S Hansen Gitte Grove Kevin L Pyke Charles Raun Kirsten Sch?ffer Lauge Tang-Christensen Mads Verma Saurabh Witgen Brent M Vrang Niels Knudsen 2014Journal of Clinical Investigation2014,,10:1
8Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention显示文摘Adipose tissue is a promising target for treating obesity and metabolic diseases.However,pharmacological agents usually fail to effectively engage adipocytes due to their extraordinarily large size and insufficient vascularization,especially in obese subjects.We have previously shown that during cold exposure,connexin43(Cx43)gap junctions are induced and activated to connect neighboring adipocytes to share limited sympathetic neuronal input amongst multiple cells.We reason the same mechanism may be leveraged to improve the efficacy of various pharmacological agents that target adipose tissue.Using an adipose tissue-specific Cx43 overexpression mouse model,we demonstrate effectiveness in connecting adipocytes to augment metabolic efficacy of theβ_(3)-adrenergic receptor agonist Mirabegron and FGF21.Additionally,combing those molecules with the Cx43 gap junction channel activator danegaptide shows a similar enhanced efficacy.In light of these findings,we propose a model in which connecting adipocytes via Cx43 gap junction channels primes adipose tissue to pharmacological agents designed to engage it.Thus,Cx43 gap junction activators hold great potential for combination with additional agents targeting adipose tissue.Yi Zhu Na Li Mingyang Huang Xi Chen Yu AAn Jianping Li Shangang Zhao Jan-Bernd Funck Jianhong Cao Zhenyan He Qingzhang Zhu Zhuzhen Zhang Zhao VWang Lin Xu Kevin W.Williams Chien Li Kevin Grove Philipp E.Scherer 2022Acta Pharmaceutica Sinica B2022,12,7:0
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