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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | 3D reconstruction of the carotid artery from two views using a single centerline显示文摘 | Kenneth R H Alan M W Peter B N | 2004 | International Congress Series2004，，： | 1 |
| 3 | Modeling thermally thick pyrolysis of wood 显示文摘 | KENNETH M B KENNETH W R RUTLAND C J | 2002 | Biomass and Bioenergy2002，22，： | 1 |
| 4 | The utilization of risk assessments in tactical command decisions 显示文摘 | WARREN W J KENNETH R S G BRUCE B | 2002 | Sei Total Environ2002，288，： | 1 |
| 5 | Molecular-genetic correlates of self-harming behaviors in eating-disordered women:Findings from a combined Canadian-German sample显示文摘 | Steiger H Fichter M Kenneth R B | | 0，，35： | 1 |
| 6 | Benefits associated with supplier integration into new product development under conditions of technology uncertainty 显示文摘 | GARY L R ROBERT B H KENNETH J P | 2002 | Business Research2002，，55： | 1 |
| 7 | Precision DC-to-AC power conversion by optimization of the output current waveform-the half bridge revisited显示文摘 | GERALD R S KENNETH M B | 1999 | IEEE Trans on Power Electronics1999，14，2： | 1 |
| 8 | Knowledge Sharing in Interorganizational Product Development Teams: The Effect of Formal and Informal Socializa?tion Mechanisms 显示文摘 | Benn Lawson Kenneth J Petersen Paul D Cousins Handfield R B | 2009 | Journal of Product Innovation Manage?ment2009，26，2： | 1 |
| 9 | Simulation studies of 4 MV X-ray spectral reconstruction by numerical analysis of transmission data显示文摘 | HUANG P H KENNETH R K BENGT E B | 1982 | Med Phys1982，9，： | 1 |
| 10 | Using AVL Trees for Fault-Tolerant Group Key Management显示文摘 | Ohad R Kenneth P B Danny D | 2002 | International Journal of Information Security2002，1，2： | 1 |
| 11 | Sex differentiation of c gonads: normal development and effects of temperature显示文摘 | Patino R Kenneth B Davis | 1996 | J Exp Zool1996，276，3： | 1 |
| 12 | Product Placement in Movies:The Effect of Prominence and Mode on Audience Recall显示文摘 | POLA B GUPTA KENNETH R LORD | 1998 | Journal of Current Issues and Research in Advertis-ing1998，，： | 1 |
| 13 | Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk显示文摘 | Georg B E Patricia B M Kenneth M R | 2011 | Nature2011，478，7367： | 1 |
| 14 | Recent pro- gress in the understanding of the structure-fuetion re- lationships o{ the globular head regions of Clq 显示文摘 | Kishore U Mihaela S K Kenneth B M R | 2002 | Immunobiol2002，205，45： | 1 |
| 15 | The effective and environmental half-life of ^137Cs at Coral Islands at the former US nuclear test site显示文摘 | William L R Cynthia L C Kenneth T B | 2003 | Journal of Environmental Radioactivity2003，69，： | 1 |
| 16 | The first high yield green route to a pharmaceutical in a room temperature ionic liquid显示文摘 | Earle Martyn J McCormac Paul B Seddon Kenneth R | 2000 | Green Chemistry2000，2，6： | 1 |
| 17 | A role for the adenomatous polyposis coil protein in chromosome segregation 显示文摘 | KENNETH B K AURORA A B JASON R S | 2001 | Nat Cell Biol2001，3，4： | 1 |
| 18 | The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation显示文摘 | NICHOLAS R CORIN Y KENNETH B | 2005 | Genorne Res2005，15，： | 1 |
| 19 | Sliding wear and fretting wear of diamondlike carbon-based, functionally graded nanocomposite coatings显示文摘 | K Miyoshi B Pohlchuck Kenneth W Street J S Zabinski J H S ers A A Voevodin R L C Wu | | 0，，： | 1 |
| 20 | Outcome After Hip Fracture in Individuals Ninety Years of Age and Older显示文摘 | Mehul R Shah Gina B Aharonoff Philip Wolinsky Joseph D Zuckerman Kenneth J Koval | 2001 | Journal of Orthopaedic Trauma2001，，1： | 1 |
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