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| 1 | Comparison of effects of six main gastrectomy procedures on patients’ quality of life assessed by Postgastrectomy Syndrome Assessment Scale-45显示文摘BACKGROUND The effects of various gastrectomy procedures on the patient’s quality of life(QOL)are not well understood.Thus,this nationwide multi-institutional crosssectional study using the Postgastrectomy Syndrome Assessment Scale-45(PGSAS-45),a well-established questionnaire designed to clarify the severity and characteristics of the postgastrectomy syndrome,was conducted.AIM To compare the effects of six main gastrectomy procedures on the postoperative QOL.METHODS Eligible questionnaires retrieved from 2368 patients who underwent either of six gastrectomy procedures[total gastrectomy with Roux-en-Y reconstruction(TGRY;n=393),proximal gastrectomy(PG;n=193),distal gastrectomy with Roux-en-Y reconstruction(DGRY;n=475),distal gastrectomy with Billroth-I reconstruction(DGBI;n=909),pylorus-preserving gastrectomy(PPG;n=313),and local resection of the stomach(LR;n=85)]were analyzed.Among the 19 main outcome measures of PGSAS-45,the severity and characteristics of postgastrectomy syndrome were compared for the aforementioned six gastrectomy procedures using analysis of means.RESULTS TGRY and PG significantly impaired the QOL of postoperative patients.Postoperative QOL was excellent in LR(cardia and pylorus were preserved with minimal resection).In procedures removing the distal stomach,diarrhea subscale(SS)and dumping SS were less frequent in PPG than in DGBI and DGRY.However,there was no difference in the postoperative QOL between DGBI and DGRY.The most noticeable adverse effects caused by gastrectomy were mealrelated distress SS,dissatisfaction at the meal,and weight loss,with significant differences among the surgical procedures.CONCLUSION Postoperative QOL greatly differed among six gastrectomy procedures.The severity and characteristics of postgastrectomy syndrome should be considered to select gastrectomy procedures,overcome surgical shortcomings,and enhance postoperative care. | Koji Nakada Yoshiyuki Kawashima Shinichi Kinami Ryoji Fukushima Hiroshi Yabusaki Akiyoshi Seshimo Naoki Hiki Keisuke Koeda Mikihiro Kano Yoshikazu Uenosono Atsushi Oshio Yasuhiro Kodera | 2021 | World Journal of Gastrointestinal Surgery2021，13，5： | 1 |
| 2 | Totally laparoscopic total gastrectomy for gastric cancer: Literature review and comparison of the procedure of esophagojejunostomy显示文摘 | Akira Umemura Keisuke Koeda Akira Sasaki Hisataka Fujiwara Yusuke Kimura Takeshi Iwaya Yuji Akiyama Go Wakabayashi | 2014 | Asian Journal of Surgery2014，，： | 1 |
| 3 | Tailored laparoscopic resection for suspected gastric gastrointestinal stromal tumors显示文摘 | Akira Sasaki Keisuke Koeda Toru Obuchi Jun Nakajima Satoshi Nishizuka Masanori Terashima Go Wakabayashi | 2010 | Surgery2010，，4： | 1 |
| 4 | Randomized Study of the Benefits of Preoperative Corticosteroid Administration on the Postoperative Morbidity and Cytokine Response in Patients Undergoing Surgery for Esophageal Cancer显示文摘 | Nobuhiro Sato Keisuke Koeda Kenichiro Ikeda Yusuke Kimura Kiichi Aoki Takeshi Iwaya Yuji Akiyama Kaoru Ishida Kazuyoshi Saito Shigeatsu Endo | 2002 | Annals of Surgery2002，，2： | 1 |
| 5 | Case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway显示文摘Here, we report a case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway. A 57-year-old Japanese woman presented with epigastric tenderness, and distal gastrectomy was performed. In the surgical specimen, histologically, the tumor tissue was composed of three subtypes of tumor components showing different histological architecture and cellular atypia, diagnosed as neuroendocrine tumor(NET) G2, NET G3, and neuroendocrine carcinoma(NEC) components. Immunohistochemically, the Ki-67-positive rates of NET G2, NET G3, and NEC components were 6.5%, 99.5% and 88.1%, respectively. Although allelic imbalance(AI) on chromosomes 1p, 3p, 8q, TP53, 18q and 22 q was commonly found in all components, AI of 4p was found in NET G3 and NEC components(but not in the NET G2 component). In contrast, AIs of 5q and 9p were found in only the NEC component. Thus, we showed the progression from NET G2 to NEC, via NET G3, within the same tumor. | Noriyuki Uesugi Ryo Sugimoto Makoto Eizuka Yasuko Fujita Mitsumasa Osakabe Keisuke Koeda Takashi Kosaka Shunichi Yanai Kazuyuki Ishida Akira Sasaki Takayuki Matsumoto Tamotsu Sugai | 2017 | World Journal of Clinical Cases2017，5，11： | 0 |
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