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| 1 | Postoperative jaundice after cardiac surgery显示文摘BACKGROUND:The frequency and pattern of hyperbili-rubinemia after open-heart surgery and its severe perioperative complications are not well clarified. The purpose of this study was to investigate the incidence and nature of postoperative jaundice in patients undergoing cardiac operation,to analyze the determinants,and to identify the clinical significance of this complication with regard to the associated morbidity and mortality. METHODS:A prospective observational study was made during the period of 2003-2004 in a Surgical Intensive Care Unit of a Cardiac Surgery Center,Athens. One hundred twenty-eight adult patients for open heart surgery were divided into three groups. Group A included 50 patients who underwent coronary artery bypass crafting(CABG),group B 31 patients who were subjected to aortic valve replacement(AVR)+CABG and group C 47 patients who underwent mitral valve replacement(MVR)+CABG. Aminotransferases,alkaline phosphatase,gamma-glutamyl-transpeptidase and both types of bilirubin were determined at admission,24 hours after the operation and thereafter according to clinical evolution. The presence of jaundice was associated with elevated serum bilirubin above 3 mg/dl. RESULTS:Hyperbilirubinemia developed in 34 patients(26.5%). The incidence of postoperative jaundice was higher in patients who were subjected to MVR+CABG than to CABG and AVR+CABG. Hyperbilirubinemia was correlated with prolonged cardiopulmonary by-passtime(P<0.001),aortic cross-clamping time(P<0.001),the use of intra aortic balloon pumping(P<0.001),the administration of inotrops and the number of blood and plasma transfusions. Postoperative jaundice resulted mainly from an increase in conjugated bilirubin. CONCLUSIONS:Although hyperbilirubinemia seems to be multifactorial,the type of operation,the preoperative hepatic dysfunction due to advanced heart failure(NYHA Ⅱ-Ⅲ) and the decreased hepatic flow during the operation seem to determine the incidence of jaundice. | Aikaterini Mastoraki Emmanouil Karatzis Sotiria Mastoraki Ioannis Kriaras Petros Sfirakis Stefanos Geroulanos | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，4： | 7 |
| 2 | Acute effects of caffeine on arterial stiffness, wave reflections, and central aortic pressures显示文摘 | Theodoros G. Papaioannou Kalliopi Karatzi Emmanouil Karatzis Christos Papamichael John P. Lekakis | 2005 | American Journal of Hypertension2005，，1： | 1 |
| 3 | 进食频率预测新发高血压及血压、动脉硬化和脉搏波反射进展率显示文摘普遍认为每天至少吃3餐,但现代生活方式正逐渐打破既往进食习惯。已发现每日进食频率可能影响多种心血管代谢风险因素,但尚未深入研究其临床价值。研究显示,与进食次数较少者相比,进食次数较多者通常血脂状况更好,胰岛素抵抗及代谢综合征发病风险更低。进食频率增加使空腹时间减少,平均血糖浓度及胰岛素分泌量降低。胰岛素浓度降低使羟甲基戊二酸单酰辅酶A还原酶活性降低,从而减少肝脏胆固醇合成。 | Karatzi K Georgiopoulos G Yannakoulia M Efthimiou E Voidonikola P Mitrakou A Manios E Alevizaki M Papamichael C Stamatelopoulos K 曲浥晨 | 2016 | 中华高血压杂志2016，24，5： | 1 |
| 4 | Postoperative jaundice after cardiac surgery 显示文摘 | Mastoraki A Karatzis E Mastoraki S | 2007 | Hepatobiliary Pancreat Dis Int2007，6，4： | 1 |
| 5 | Postopera- tive jaundice after cardiac surgery显示文摘 | MASTORAKI A KARATZIS E MASTORAKI S | 2007 | Hepatobiliary Pancreat Dis Int2007，6，4： | 1 |
| 6 | Acute combined effects of olive oil and wine on pressure wave reflections: another beneficial influence of the Mediterranean diet antioxidants?显示文摘 | Christos M Papamichael Kalliopi N Karatzi Theodore G Papaioannou Emmanouil N Karatzis Paraskevi Katsichti Vasilis Sideris Nikolaos Zakopoulos Antonis Zampelas John P Lekakis | 2008 | Journal of Hypertension2008，，2： | 1 |
| 7 | Myocardial performance index(Tei index):evaluating its application to myocardial infarction显示文摘 | Karatzis EN Giannakopoulou AT Papadakis JE | 2009 | Hellenic J Cardiol2009，50，1： | 1 |
| 8 | Rapid effect of pravastatin on endothelial function and lipid peroxldation in unstableangina显示文摘 | Karatzis E Lekakis J Papamichael C | 2005 | Int JCardiol2005，101，1： | 1 |
| 9 | Long-term prognostic role offlow-mediated dilatation of the brachial artery after acute coronary syndromeswithout ST elevation显示文摘 | Karatzis EN Ikonomidis I Vamvakou GD | 2006 | Am J CarHiol2006，98，： | 1 |
| 10 | Impact of the metabolic syndrome on atrial size in patients with new-onset atrial fibrillation显示文摘 | Nieolaou VN Papadakis JE Karatzis EN | 2007 | Angiology2007，58，1： | 1 |
| 11 | Rapid effect of pravastatin on endothelial function and lipid peroxidation in unstable angina 显示文摘 | Karatzis E Lekakis J Papamichael C | 2005 | Int J Cardiol2005，101，1： | 1 |
| 12 | Myocardial performance index (Tei index):Evaluating its application to myocardial infarction显示文摘 | KARATZIS E N GIANNAKOPOULOU A T | 2009 | Hellenic J Cardiol2009，50，1： | 1 |
| 13 | Myocard- ial performance index (Tei index): evaluating its application to myocardial infarction显示文摘 | Karatzis EN Giannakopoulou AT Papadakis JE | 2009 | Hellenic J Cardiol2009，50，1： | 1 |
| 14 | Red Wine Acutely Induces Favorable Effects on Wave Reflections and Central Pressures in Coronary Artery Disease Patients显示文摘 | Kalliopi N. Karatzi Christos M. Papamichael Emmanouil N. Karatzis Theodoros G. Papaioannou Konstantinos A. Aznaouridis Paraskevi P. Katsichti Kimon S. Stamatelopoulos Antonis Zampelas John P. Lekakis Myron E. Mavrikakis | 2005 | American Journal of Hypertension2005，，9： | 1 |
| 15 | Trans- mission of calibration errors (input) by generalized transfer functions to the aortic pressures (output) at different hemodynamic states显示文摘 | Papaioannou TG Lekakis JP Karatzis EN | 2006 | Int J Cardiol2006，110，1： | 1 |
| 16 | Acute effects of caffeine on arterial stiffness,wave reflections,and central aortic pressures显示文摘 | Papaioannou TG Karatzi K Karatzis E | 2005 | Am J Hypertens2005，18，1： | 1 |
| 17 | Polymorphisms of the TNF-α and ACE Genes, and Renal Scarring in Infants With Urinary Tract Infection显示文摘 | A. Savvidou M. Bitsori D.M. Choumerianou M. Karatzi M. Kalmanti E. Galanakis | 2010 | The Journal of Urology2010，，2： | 1 |
| 18 | 进食频率预测新发高血压和动脉硬化、波反射的进展显示文摘横断面研究证据表明,进食频率与血压、高血压及相关的靶器官损害有关。本研究旨在对无心血管病成人进行〉5年随访,前瞻性评估进食频率能否作为动脉粥样硬化进展和新发高血压的预测指标。方法:基线纳入一个普通人群样本中的115名非糖尿病研究受试者[(54.0±9.1)岁,45名女性]作为研究对象,评估膳食的进食频率,在基线和随访5年后评估与进食频率有关的代谢参数,动脉硬化的标志物,包括增强指数、脉搏波传导速度(pulse wave velocity,PWV)、收缩压、舒张压水平。 | 刘莉 叶鹏 Karatzi K Georgiopoulos G Yannakoulia M Efthimiou E Voidonikola P Mitrakou A Manios E Alevizaki M Papamichael C Stamatelopoulos K | 2016 | 中华高血压杂志2016，24，2： | 1 |
| 19 | Effect of coffee on endothelial function in healthy subjects: the role of caffeine 显示文摘 | Papamichael CM Aznaouridis KA Karatzis EN | 2005 | ClinSei (Lond)2005，109，1： | 1 |
| 20 | Myocardial performance index (Tei index); Evaluating its application to myocardial infarction显示文摘 | Karatzis EN Giannakoponlou AT Papadakis JE | 2009 | Hellenic J Cardiol2009，50，1： | 1 |
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