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| 1 | Screening pre-bariatric surgery patients for esophageal disease with esophageal capsule endoscopy显示文摘AIM:To determine if esophageal capsule endoscopy(ECE)is an adequate diagnostic alternative to esophagogastroduodenoscopy(EGD)in pre-bariatric surgery patients.METHODS:We conducted a prospective pilot study to assess the diagnostic accuracy of ECE(PillCam ESO2,Given Imaging)vs conventional EGD in pre-bariatric surgery patients.Patients who were scheduled for bariatric surgery and referred for pre-operative EGD were prospectively enrolled.All patients underwent ECE followed by standard EGD.Two experienced gastroenterologists blinded to the patient’s history and the findings of the EGD reviewed the ECE and documented their findings.The gold standard was the findings on EGD.RESULTS:Ten patients with an average body mass index of 50 kg/m2were enrolled and completed the study.ECE identified 11 of 14(79%)positive esophageal/gastroesophageal junction(GEJ)findings and 14of 17(82%)combined esophageal and gastric findings identified on EGD.Fisher’s exact test was used to compare the findings and no significant difference was found between ECE and EGD(P=0.64 for esophageal/GEJ and P=0.66 for combined esophageal and gastric findings respectively).Of the positive esophageal/GEJ findings,ECE failed to identify the following:hiatal hernia in two patients,mild esophagitis in two patients,and mild Schatzki ring in two patients.ECE was able to identify the entire esophagus in 100%,gastric cardia in0%,gastric body in 100%,gastric antrum in 70%,pylorus in 60%,and duodenum in 0%.CONCLUSION:There were no significant differences in the likelihood of identifying a positive finding using ECE compared with EGD in preoperative evaluation of bariatric patients. | Ashish Shah Erica Boettcher Marianne Fahmy Thomas Savides Santiago Horgan Garth R Jacobsen Bryan J Sandler Michael Sedrak Denise Kalmaz | 2013 | World Journal of Gastroenterology2013，19，37： | 7 |
| 2 | Systematic review: Safety of balloon assisted enteroscopy in Crohn's disease显示文摘AIM To determine the overall and comparative risk of procedure related perforation of balloon assisted enteroscopy(BAE) in Crohn's disease(CD). METHODS Systematic review(PROSPERO #CRD42015016381) of studies reporting on CD patients undergoing BAE. Seventy-three studies reporting on 1812 patients undergoing 2340 BAEs were included. Primary outcome of interest was the overall and comparative risk of procedure related perforation of diagnostic BAE in CD. Secondary outcomes of interest were risk of procedure related perforation of diagnostic double balloon enteroscopy(DBE), risk of procedure related perforation of therapeutic BAE, efficacy of stricture dilation, and clinical utility of endoscopically assessing small bowel disease activity.RESULTS Per procedure perforation rate of diagnostic BAE in CD was 0.15%(95%CI: 0.05-0.45), which was similar to diagnostic BAE for all indications(0.11%; IRR = 1.41, 95%CI: 0.28-4.50). Per procedure perforation rate of diagnostic DBE in CD was 0.12%(95%CI: 0.03-0.44), which was similar to diagnostic DBE for all indications(0.22%; IRR = 0.54, 95%CI: 0.06-0.24). Per procedure perforation rate of therapeutic BAE in CD was 1.74%(95%CI: 0.85-3.55). Eighty-six percentof therapeutic perforations were secondary to stricture dilation. Dilation was attempted in 207 patients and 30% required surgery during median follow-up of 18 months. When diagnostic BAE assessed small bowel disease activity, changes in medical therapy resulted in endoscopic improvement in 77% of patients. CONCLUSION Diagnostic BAE in CD has a similar rate of perforation as diagnostic BAE for all indications and can be safely performed in assessment of mucosal healing. | Ahilan Arulanandan Parambir S Dulai Siddharth Singh William J Sandborn Denise Kalmaz | 2016 | World Journal of Gastroenterology2016，22，40： | 2 |
| 3 | Carcinogenicity and epidemiological profile analysis of vinyl chloride and polyvinyl chloride显示文摘 | KALMAZ E E KALMAZ G D | 1984 | Regul Toxicol Pharmacol1984，4，1： | 1 |
| 4 | Mathematical model and computer simulation of the population dynamics of zooplankton in lake and estuary ecosystems 显示文摘 | Kalmaz E V | 1978 | Ecological Modelling1978，5，3： | 1 |
| 5 | Quality of colonoscopy withdrawal technique and variability in adenoma detection rates (with videos)显示文摘 | Robert H. Lee Raymond S. Tang V. Raman Muthusamy Samuel B. Ho Nimeesh K. Shah Laura Wetzel Andrew S. Bain Erin E. Mackintosh Aeri M. Paek Ana Maria Crissien Lida Jafari Saraf Denise M. Kalmaz Thomas J. Savides | 2011 | Gastrointestinal Endoscopy2011，，： | 1 |
| 6 | Outcomes of acute rejection after interferon therapy in liver transplant recip- ients 显示文摘 | Saab S Kalmaz D Gajjar NA | 2004 | Liver Transpl2004，10，7： | 1 |
| 7 | Trace metals,surface receptors and growth of human normal leukemia lymphocytes显示文摘 | Carpentieri U Kalmaz G Ezell E | 1988 | Auticancer Res1988，8，6： | 1 |
| 8 | Tu1413 Proficiency of GI Trainees in Independently Attaining Quality Benchmarks in Colonoscopy显示文摘 | Robert H. Lee Lida Jafari Saraf V. Raman Muthusamy Denise Kalmaz Samuel B. Ho Erin E. Mackintosh Andrew J. Bain Thomas J. Savides | 2011 | Gastrointestinal Endoscopy2011，，4： | 1 |
| 9 | Low yield of routine duodenal biopsies for evaluation of abdominal pain显示文摘AIM: To determine the yield of biopsying normal duodenal mucosa for investigation of abdominal pain.METHODS: This is a retrospective chart review of consecutive patients who underwent esophagogastroduodenoscopy(EGD) with duodenal biopsies of normal appearing duodenal mucosa for an indication that included abdominal pain. All the patients in this study were identified from an electronic endoscopy database at a single academic medical center and had an EGD with duodenal biopsies performed over a 4-year period. New diagnoses that were made as a direct result of duodenal biopsies were identified. All duodenal pathology reports and endoscopy records were reviewed for indications to perform the examination as well as the findings; all the medical records were reviewed. Exclusion criteria included age less than 18 years, duodenal mass, nodule, or polyp, endoscopic duodenitis, duodenal scalloping, known celiac disease, positive celiac serology, Crohns disease, or history of bone marrow transplant. Information was collected in a de-identified database with pertinent demographic information including human immunodeficiency virus(HIV) status, and descriptive statistics were performed.RESULTS: About 300 patients underwent EGD with biopsies of benign appearing or normal appearing duodenal mucosa. The mean age of patients was 44.1 ± 16.8 years; 189 of 300(63%) were female. A mean of 4.3 duodenal biopsies were performed in eachpatient. In the subgroup of patients with abdominal pain without anemia, diarrhea, or weight loss the mean age was 43.4 ± 16.3 years. Duodenal biopsies performed for an indication that included abdominal pain resulting in 4 new diagnoses(3 celiac disease and 1 giardiasis) for an overall yield of 1.3%. 183 patients with abdominal pain without anemia, diarrhea, or weight loss(out of the total 300 patients) underwent duodenal biopsy of duodenal mucosa resulting in three new diagnoses(two cases of celiac disease and one giardiasis) for a yield of 1.6%. Duodenal biopsies of 19 HIV patients presenting for evaluation of abdominal pain did not reveal any new diagnoses. Information pertaining to new diagnoses is provided.CONCLUSION: Routine biopsy of normal appearing duodena in patients with abdominal pain should be reserved for those with a high pre-test probability given its low diagnostic yield. | Sterling M Dubin Wilson T Kwong Denise Kalmaz Thomas J Savides | 2015 | World Journal of Gastroenterology2015，21，24： | 0 |
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