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3篇 您的检索式：作者名="Kaidong Lin"

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		题名	作者	年代	出处	被引量
	1	Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition显示文摘Sphingosine-1-phosphate(S1P)is an important bioactive lipid molecule in cell membrane metabolism and binds to G proteincoupled S1P receptors(S1PRs)to regulate embryonic development,physiological homeostasis,and pathogenic processes in various organs.S1PRs are lipid-sensing receptors and are therapeutic targets for drug development,including potential treatment of COVID-19.Herein,we present five cryo-electron microscopy structures of S1PRs bound to diverse drug agonists and the heterotrimeric Gi protein.Our structural and functional assays demonstrate the different binding modes of chemically distinct agonists of S1PRs,reveal the mechanical switch that activates these receptors,and provide a framework for understanding ligand selectivity and G protein coupling.	Yuan Yuan Guowen Jia Chao Wu Wei Wang Lin Cheng Qian Li Ziyan Li Kaidong Luo Shengyong Yang Wei Yan Zhaoming Su Zhenhua Shao	2021	Cell Research2021，31，12：	1
	2	Computed tomographic-guided iodine-125 interstitial implants for malignant thoracic tumors显示文摘	Qiming Huang Jin Chen Qunlin Chen Qingquan Lai Siqing Cai Kaidong Luo Zhengyu Lin	2013	European Journal of Radiology2013，，11：	1
	3	Optimal Operation of Energy Hub Based Micro-energy Network with Integration of Renewables and Energy Storages显示文摘This study proposes an optimized model of a micro-energy network(MEN)that includes electricity and natural gas with integrated solar,wind,and energy storage systems(ESSs).The proposed model is based on energy hubs(EHs)and it aims to minimize operation costs and greenhouse emissions.The research is motivated by the increasing use of renewable energies and ESSs for secure energy supply while reducing operation costs and environment effects.A general algebraic modeling system(GAMS)is used to solve the optimal operation problem in the MEN.The results demonstrate that an optimal MEN formed by multiple EHs can provide appropriate and flexible responses to fluctuations in electricity prices and adjustments between time periods and seasons.It also yields significant reductions in operation costs and emissions.The proposed model can contribute to future research by providing a more efficient network model(as compared with the traditional electricity supply system)to scale down the environmental and economic impacts of electricity storage and supply systems on MEN operation.	Thanhtung Ha Ying Xue Kaidong Lin Yongjun Zhang Vu Van Thang Thanhha Nguyen	2022	Journal of Modern Power Systems and Clean Energy2022，10，1：	0

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