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| 1 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 2 | Development of an effective process for utilization of collagen from livestock and fish waste显示文摘 | S Morimura H Nagata Y Uemura A Fahmi T Shigematsu K Kida | 2002 | Process Biochemistry2002，，12： | 2 |
| 3 | Repeated-batch fermentation process using a thermotolerant flocculating yeast constructed by protoplast fusion 显示文摘 | KUME K NORIMURA S | 1992 | Journal of Fermentation and Biotechnology1992，，74： | 1 |
| 4 | New diagnostic imaging of gastointestinal tumors:a preliminary study of three-dimensional tumor structure and volumetry 显示文摘 | Kikuchi S Kida M Kobayashi K | 2005 | Anticancer Res2005，25，4： | 1 |
| 5 | A functional role for CREB as a positive regulator ofmemory formation and LTP 显示文摘 | Kida S | 2012 | Exp Neurobiol2012，21，4： | 1 |
| 6 | Ruptured bronchial artery aneurysm associated with bronchiectasis: a case report显示文摘 | Mizuguchi S Inoue K Kida A | 2009 | Ann Thorac Cardiovasc Surg2009，15，： | 1 |
| 7 | Ethanol production by repeated-batch fermentation at high temperature in a molasses medium containing a high concentration of total sugar by a thermotolerant flocculatation yeast with improved salt-tolerance 显示文摘 | LING Z L KIDA K | 1997 | Journal of Fermentation and Bioengineering1997，，83： | 1 |
| 8 | Expression and induction by IL-6 of the normal and variant genes for human plasminogen显示文摘 | kida M Wakahayashi S Ichinose A | 1997 | Biochem Biophys Res Commun1997，230，1： | 1 |
| 9 | Ruptured bronchial artery an-eurysm associated with bronchiectasis:a case report显示文摘 | Mizuguchi S Inoue K Kida A | 2009 | Ann Tho-rac Cardiovasc Surg2009，15，2： | 1 |
| 10 | Improved cerebral perfusion and metabolism after stenting for basilar artery stenosis: technical ease report显示文摘 | Uchiyama N Kida S Watanabe T | 2001 | Neuresurgery2001，48，6： | 1 |
| 11 | Endoscopic Mucosal Resection in the Management of Gastric Carcinod Tumors显示文摘 | Ichikawa J Tanabe S Kida Y | 2003 | Endoscopy2003，35，： | 1 |
| 12 | Gamma Knife radiosurgery for hemangiomas of the cavernous sinus:a seveninstitute study in Japan显示文摘 | Yamamoto M Kida Y Fukuoka S | | 0，，： | 1 |
| 13 | Staging of gastric cancer with endoscopic uhrasonography and endoscopic mucosal resection 显示文摘 | Kida M Tanabe S Watanabe M | 1998 | Endoscopy1998，301，： | 1 |
| 14 | Crystal Structure and Magnetic Property of the Binuclear Manganese(Ⅲ) Complex2(ClO4)显示文摘 | Matsumoto N Zhuang J Z Okawa H Kida S | 1989 | Inorg Chim Acta1989，160，2： | 1 |
| 15 | Clinical efficacy and safety of biapenemfor febrile neutropenia in patients with underlying hem-atopoietic diseases:a multi-institutional study显示文摘 | Nakagawa Y Suzuki K Hirose T Chou T Fujisawa S Kida M | 2011 | J In-fect Chemother2011，16，： | 1 |
| 16 | Production of angiotensin I converting enzyme inhibitory peptides from sea bream scales 显示文摘 | Fahmi A Morimur S Guo H C Shigematsu T Kida K Uemura Y | 2004 | Process Biochemistry2004，39，10： | 1 |
| 17 | Partial SPAST and DPY30 deletions in a Japanese spastic paraplegia type 4 family显示文摘 | Miura S Shibata H Kida H | 2011 | Neurogenetics2011，12，1： | 1 |
| 18 | Involvement of STAT3 in immune evasion during lung tumorigenesis 显示文摘 | Kida H Ihara S Kumanogoh A | 2013 | Oncoimmunology2013，2，22： | 1 |
| 19 | CT during selective arteriography: anatomical assessment of unruptured intracranial aneurysms before endovascular treatment 显示文摘 | Nomura M Kida S Uchiyama N | 2001 | Neuroradiology2001，43，6： | 1 |
| 20 | Design and synthesis of a Tat-related gene transporter: A tool for carrying the adenovirus vector into cells显示文摘 | KIDA S MAEDA M HOJO K | 2006 | Bioorg Med Chem Lett2006，16，3： | 1 |
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