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| 1 | 曲马多治疗糖尿病性神经疼痛的双盲随机试验显示文摘目的 :本研究旨在评价曲马多治疗糖尿病性神经痛的有效性和安全性。背景 :糖尿病性神经痛是糖尿病患者的主要症状 ,其治疗和其他的末梢神经病变一样 ,不能令人满意。曲马多是作用于中枢的镇痛剂 ,用于治疗中到重度疼痛。方法 :多中心、门诊病例、随机、双盲、安慰剂做对照、设置平行组的研究 ,包括清洗期 (在此期间停用所有镇痛剂 )和一个为期 42天的双盲治疗期。总共有 1 31名患糖尿病性神经痛的患者按每日 4次接受了曲马多 (n =65)或看上去与曲马多相同的安慰剂胶囊治疗 (n =66)。 42天的治疗结束后或治疗中断后比较曲马多组和安慰剂组平均疼痛强度评分作出主要有效性分析 ;次要有效性分析为疼痛缓解率评分和根据日常活动和睡眠状况作出的对生活质量的评估。结果 :曲马多平均剂量为 2 1 0mg/天 ,治疗糖尿病性神经痛较安慰剂有显著疗效 (P≤ 0 .0 0 1 )。曲马多组患者生理(P =0 .0 2 )和社会功能 (P =0 .0 4 )的评分显著优于安慰剂组。未发现对睡眠有显著治疗作用。曲马多最常见的不良反应是恶心 ,便秘 ,头疼和嗜睡。结论 | Harati Y Gooch C Swenson M Green D Raskin P Donofrio P Cornblath D Sachdeo R Siu CO Kamin M | 2001 | 中国疼痛医学杂志2001,7,1: | 2 |
| 2 | Metasurface-based multi-harmonic freeelectron light source显示文摘Metasurfaces are subwavelength spatial variations in geometry and material where the structures are of negligible thickness compared to the wavelength of light and are optimized for far-field applications,such as controlling the wavefronts of electromagnetic waves.Here,we investigate the potential of the metasurface near-field profile,generated by an incident few-cycle pulse laser,to facilitate the generation of high-frequency light from free electrons.In particular,the metasurface near-field contains higher-order spatial harmonics that can be leveraged to generate multiple higher-harmonic X-ray frequency peaks.We show that the X-ray spectral profile can be arbitrarily shaped by controlling the metasurface geometry,the electron energy,and the incidence angle of the laser input.Using ab initio simulations,we predict bright and monoenergetic X-rays,achieving energies of 30 keV(with harmonics spaced by 3 keV)from 5-MeV electrons using 3.4-eV plasmon polaritons on a metasurface with a period of 85 nm.As an example,we present the design of a four-color X-ray source,a potential candidate for tabletop multicolor hard X-ray spectroscopy.Our developments could help pave the way for compact multi-harmonic sources of high-energy photons,which have potential applications in industry,medicine,and the fundamental sciences. | Gilles Rosolen Liang Jie Wong Nicholas Rivera Bjorn Maes Marin Soljačić Ido Kaminer | 2018 | Light(Science & Applications)2018,7,1: | 2 |
| 3 | Chemical vapor deposition of Si nanowires nucleated by TiSi2 islands on Si显示文摘 | Kamins T I Stanley Williams R Chang Y L | 2000 | Appl Phys Lett2000,76,5: | 2 |
| 4 | Source-type solutions of degenerate diffusion equations with absorption显示文摘 | KAMIN S PELETIER L A | 1985 | Israel J Math1985,50,3: | 1 |
| 5 | Rotating ring-disk enzyme elec- trode for biocatalysis kinetic studies and characterization of the immobilized enzyme layer 显示文摘 | Kamin R A Wilson G S | 1980 | Anal Chem1980,52,: | 1 |
| 6 | Explaining the global pattern of current account imbalances显示文摘 | Joseph W. Gruber Steven B. Kamin | 2007 | Journal of International Money and Finance2007,,4: | 1 |
| 7 | Muscle preservation by prolonged sensory protection显示文摘 | Papakonstantinou KC Kamin E Terzis JK | 2002 | J Reconstr Microsurg2002,18,3: | 1 |
| 8 | Growth and structure of chemically vapor deposited Ge nanowires on Si substrates显示文摘 | Kamins T I Li X Williams R S | 2004 | Nano Lett2004,4,3: | 1 |
| 9 | Acne scarring: a classification system and review of treatment options显示文摘 | Jacob CI Dover JS Kaminer MS | 2001 | J Am Acad Dermato12001,45,1: | 1 |
| 10 | Pearls and pitfalls in the emergency department evaluation of abdominal pain显示文摘 | Nowicki TA Courtney DS | 2003 | Emerg Med Clin North Am2003,21,1: | 1 |
| 11 | Development of a flight test system for unmanned air vehicles显示文摘 | Hallberg E Kaminer I Pascoal A | 1999 | IEEE Control System Magazine1999,19,1: | 1 |
| 12 | Challenges and opportunities of group therapy for adolescent substance abuse: A critical review 显示文摘 | Yifrah Kaminer | 2005 | Addictive Be- haviors2005,30,2005: | 1 |
| 13 | Electrical characteristics of germanium n+/p junctions obtained using rapid thermal annealing of coimplanted P and Sb显示文摘 | THAREJA G CHENG S KAMINS T | 2011 | IEEE Electron Device Letters2011,32,5: | 1 |
| 14 | Chemical vapor deposition of Si nanowires nucleated by TiSi2 islands on Si 显示文摘 | Kamins T I Williams R S Chen Y Chang Y L Chang Y A | 2000 | Applied Physics Letters2000,76,: | 1 |
| 15 | Tramadol allows reduction of noproxen dose among patients with naproxerr responsive osteoarthritis pain:a randomized,double- blind,placebo, controlled study显示文摘 | Schnitzer TJ Kamin M Olson WH | 1999 | Arthritis Rheum1999,42,7: | 1 |
| 16 | Research joint ventures and R&D cartels显示文摘 | Kamin M I Muller E Zang 1 | 1992 | American Economic Review1992,,82: | 1 |
| 17 | A model for conduction in polycrystalline silicon-part Ⅰ: Theory 显示文摘 | Mandurah M M Saraswat K C Kamins T I | 1981 | IEEE Trans Electron Devices1981,,28: | 1 |
| 18 | The use of nonablative radiofrequency technology to tighten the lower face and neck显示文摘 | HSU T S KAMINER M S | 2003 | Semin Cutan Med Surg2003,22,2: | 1 |
| 19 | Research Joint Venture and R&D Cartds显示文摘 | KAMIN M I MULLER E ZHANG I | 1992 | American Economic Review1992,82,: | 1 |
| 20 | Suitable blending method of lipiodol-cisplatin in transcatheter arterial embolization for hepatocellular carcinoma:evaluation of sustained release and accumulation nature显示文摘 | Takaki Y Kaminou T Shabana M | 2008 | Hepatogastroenterology2008,55,81: | 1 |