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73篇 您的检索式:作者名="Gooch C"
    题名 作者 年代 出处 被引量
1曲马多治疗糖尿病性神经疼痛的双盲随机试验显示文摘目的 :本研究旨在评价曲马多治疗糖尿病性神经痛的有效性和安全性。背景 :糖尿病性神经痛是糖尿病患者的主要症状 ,其治疗和其他的末梢神经病变一样 ,不能令人满意。曲马多是作用于中枢的镇痛剂 ,用于治疗中到重度疼痛。方法 :多中心、门诊病例、随机、双盲、安慰剂做对照、设置平行组的研究 ,包括清洗期 (在此期间停用所有镇痛剂 )和一个为期 42天的双盲治疗期。总共有 1 31名患糖尿病性神经痛的患者按每日 4次接受了曲马多 (n =65)或看上去与曲马多相同的安慰剂胶囊治疗 (n =66)。 42天的治疗结束后或治疗中断后比较曲马多组和安慰剂组平均疼痛强度评分作出主要有效性分析 ;次要有效性分析为疼痛缓解率评分和根据日常活动和睡眠状况作出的对生活质量的评估。结果 :曲马多平均剂量为 2 1 0mg/天 ,治疗糖尿病性神经痛较安慰剂有显著疗效 (P≤ 0 .0 0 1 )。曲马多组患者生理(P =0 .0 2 )和社会功能 (P =0 .0 4 )的评分显著优于安慰剂组。未发现对睡眠有显著治疗作用。曲马多最常见的不良反应是恶心 ,便秘 ,头疼和嗜睡。结论Harati Y Gooch C Swenson M Green D Raskin P Donofrio P Cornblath D Sachdeo R Siu CO Kamin M 2001中国疼痛医学杂志2001,7,1:2
2Maintenance of the long-term effectiveness of tramadol in treatment of the pain of diabetic neuropathy显示文摘 Gooch C Swenson M 2000J Diabetes Complication2000,14,2:1
3Real-time video abstraction 显示文摘WINNEMOLLER H OLSEN S C GOOCH B 2006ACM Transactions on Graphics2006,,:1
4Doubleblind randomized trial of tramal for the pain of diabetic neuropathy显示文摘Harati Y Gooch C Swenson M 1998Neurology1998,50,:1
5Real-time Video Abstraction 显示文摘WINNEMOLLER H OLSEN S C GOOCH B 2006ACM Tram Graph2006,25,:1
6Double blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy显示文摘HARATO Y GOOCH C SWENSON M 1998Neurology1998,50,:1
7Real-time video abstraction 显示文摘Winnemoller H Olsen S C Gooch B 2006ACM Transactions on Graphics2006,25,3:1
8Growth and survival of Vibrio parahaemotyticus in post harvest American oyster显示文摘Gooch J A Depaola J C BowemsA 2002J Food Protect2002,,65:1
9Real-Time Video Abstraction显示文摘Holger Winnemoller Seven C Olsen Bruce Gooch 2006ACM Transactions on Graphics2006,25,3:1
10The effect of autologous mesenchymal stem cel s on the biomechanics and histology of gelcol agen sponge constructs used for rabbit patel ar tendon repair显示文摘Juncosa-Melvin N Boivin GP Gooch C 0,,02:1
11Evaluation of two Direct Plation methods using nonoradioactive probes for enumeration of Vibrio parahaemolytcus in oyster显示文摘Gooch J A depaolar A Kaysner C A 2001Appl and Environ Microbiol2001,67,2:1
12Hepatitis B virus infection in dentistry显示文摘Bell D M Shapiro C N Gooch B F 1993J Public Health Dent1993,53,2:1
13Double-blind random- ized trial of tramadol for the treatment of the pain of diabetic neuropathy显示文摘Harati Y Gooch C Swenson M 1998Neurology1998,50,6:1
14Maintenance of the long-term effectiveness of tramadol in treatment of the pain of diabetic neuropathy显示文摘Harati Y Gooch C Swenson M 2000J Diabetes Complications2000,14,2:1
15Growth and survival of Vibrio parahaemolyticus in post harvest American oyster显示文摘Gooch J A Depaola J C Bowems A 2002J Food Protect2002,,65:1
16The use of mesenchymal stem cel s in col agen-based scaffolds for tissue-engineered repair of tendons显示文摘Butler DL Gooch C Kinneberg KR 0,,05:1
17Real-time video abstraction显示文摘Winnem?ller H Olsen S C Gooch B 2006ACM Transactions on Graphics(TOG)2006,25,3:1
18Growth andsurvival of Vibrio parahae molyticus in post harvestAmerican oysters显示文摘Gooch J A De Paola A BowersJ C 2002J Food Prot2002,65,:1
19Double-blind randomized trial of tramadol for treat-ment of the pain of diabetic neuropathy显示文摘HaratiY Gooch C 1998Neurology1998,50,6:1
20Optical characteristic of twisted nematic liquid-crystal films 显示文摘Gooch C H Tarry H A 1974Electronic Letters1974,10,:1
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