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412篇 您的检索式:作者名="K Heining"
    题名 作者 年代 出处 被引量
1Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors显示文摘AIM:To investigate the expression and potential prognostic role of vascular endothelial growth factor(VEGF) and endoglin in gastroenteropancreatic neuroendocrine tumors(GEP-NETs) . METHODS:Microvessel density(MVD) in GEP-NETs was evaluated using endoglin and CD31 immunohistochemistry.In addition,tissue levels of endoglin and VEGF were determined in homogenates by ELISA. RESULTS:Endoglin was highly expressed on tumor endothelial cells.CD31 MVD in GEP-NETs was significantly higher compared to endoglin MVD(P<0.01) .Two-tofour-fold higher tissue levels of endoglin and VEGF were seen in tumors compared to associated normal tissue. This increased endoglin tissue expression in tumors was significantly related to tumor size(P<0.01) ,presence of metastases(P=0.04) ,and a more advanced tumor stage(P=0.02) ,whereas expression of VEGF was not. CONCLUSION:We suggest that endoglin is a potential marker to indicate and predict metastases,which might be useful in the post-resection therapeutic approach of patients with GEP-NETs.Patricia Kuiper Lukas JAC Hawinkels Eveline SM de Jonge-Muller Izk Biemond Cornelis BHW Lamers Hein W Verspaget 2011World Journal of Gastroenterology2011,17,2:4
2EU clean coal technology-co- combustion of coal and biomass显示文摘Hein K R G Bemtgen J M 1998Fuel Processing Tech- nology1998,54,:1
3Fluid inclusion petrogra-phy 显示文摘VAN DEN K A M HEIN U F 2001Lithos2001,55,1:1
4Growth response of a deep-water ferromanganese crust to evolution of the Neogene Indian Ocean显示文摘Banakar V K Hein J R 2000Marine Geology2000,162,2:1
5Endogenous abscisic acid and indole- 3-acetic acid and somatic embryogensis in cultured leaf explants of Pennisetum purpureum Schumaeher 显示文摘Rajasekaran K Hein MB and Vasil IK 1987Plant Pohysiol1987,,84:1
660 Myr records of major elements and Pb-Nd isotopes from hydrogenous ferromanganese crusts: reconstruction of seawater paleochemistry显示文摘FRANK M ONION R K HEIN J R 1999Geochinica et Cosmochimica Acta1999,63,:1
7Evaluation of free andpeptide bound collagen crosslink excretion in differentskeletal diseases 显示文摘Muller A Jakob K Hein GE Ann Rheum Di0,,:1
8Using Wet-FGD systems for mercury removal 显示文摘Dfaz-Somoano M Unterberger S Hein K R 2005Environ Monit2005,7,9:1
9Lysyl oxidases:expression in the fetal membranes and placenta显示文摘Hein S Yamamoto SY Okazaki K 2001Placenta2001,22,1:1
10Virus- induced gene silencing-based functional characterization of genes associated with powdery mildew resistance in barley显示文摘Hein I Barciszewska-paca M Hrubikova K 2005Plant Physio12005,138,4:1
11Behaviour of gaseous chlorine and alkali metals during biomass thermal utilisation显示文摘WEI Xiao-lin SCHNELL U HEIN K 2005Fuel2005,84,78:1
12Hafnium isotope stratigraphy of ferromanganese crusts 显示文摘Lee D-C Halliday A N Hein J R Burton K W Christensen J N Günther D 1999Science1999,285,5429:1
13EU clean coal technology-co-combustion of coal and biomass显示文摘Hein K R G Bemtgen J M 1998Fuel Processing Technology1998,54,3:1
14Role of transforming growth factor-beta in the development of the mouse embryo显示文摘Heine U I Minoz E F Flanders K C 1987J Cell Biol1987,105,62:1
15Innovations and the role of complementarities in a strategie theory of the firm 显示文摘Stieglitz N Heine K 2007Strategie Management Journal2007,28,1:1
16Amacrokinetic model for dimensioning of bilfilters for VOC and odour treatment显示文摘J Streese M Schlegelmilch K Heining 2005Waste Management2005,25,:1
17New generation of chito- san-encapsulated ZnO quantum dots loaded with drug: syn- thesis, characterization and in vitro drug delivery response 显示文摘Yuan Q Hein S Misra R D K 2010Acta Biomater2010,6,:1
18Orthopaedic practice in total hip arthroplasty and total knee arthroplasty:results from the Global Orthopaedic Registry (GLORY)显示文摘Waddell J Johnson K Hein W 0,,:1
19Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survival显示文摘Hein OV Birnbaum J Wemecke K 2006Ann Thorac Surg2006,81,3:1
20Virus-induced gene silencing-based functional characterization of genes associated with powdery mildew resistance in barley 显示文摘Hein I Barciszewska-Pacak M Hrubikova K 2005Plant Physiology2005,138,:1
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