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| 1 | High level of serum AMBP is associated with poor response to paclitaxel–capecitabine chemotherapy in advanced gastric cancer patients显示文摘 | Hao Huang Yong Han Jing Gao Junnan Feng Lei Zhu Like Qu Lin Shen Chengchao Shou | 2013 | Medical Oncology2013，，4： | 3 |
| 2 | Aiphanol, a native compound, suppresses angiogenesis via dual-targeting VEGFR2 and C0X2显示文摘Dear Editor,Pathological neo-vascularization is a hallmark of cancer and several diseases.Accumulating evidence supports the notion that antiangiogenic treatment can abolish tumor angiogenesis to achieve Ion ger disease-free survival.Although growth factors and their receptors function as the main drivers in angiogenesis,the involvement of other regulators,e.g.,Cyclooxygenase-2(COX2),^(1) should also be con sidered,especially for managi ng the resista nee to therapies against receptor tyrosine kinases(RTKs). | Shanmei Chen Junnan Feng Chuanke Zhao Lixin Wang Lin Meng Caiyun Liu Shaoqing Cai Yanxing Jia Like Qu Chengchao Shou | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
| 3 | Reconstructing cell lineage trees with genomic barcoding:approaches and applications显示文摘In multicellular organisms,developmental history of cell divisions and functional annotation of terminal cells can be organized into a cell lineage tree(CLT).The reconstruction of the CLT has long been a major goal in developmental biology and other related fields.Recent technological advancements,especially those in editable genomic barcodes and single-cell high-throughput sequencing,have sparked a new wave of experimental methods for reconstructing CLTs.Here we review the existing experimental approaches to the reconstruction of CLT,which are broadly categorized as either image-based or DNA barcode-based methods.In addition,we present a summary of the related literature based on the biological insight pro-vided by the obtained CLTs.Moreover,we discuss the challenges that will arise as more and better CLT data become available in the near future.Genomic barcoding-based CLT reconstructions and analyses,due to their wide applicability and high scalability,offer the potential for novel biological discoveries,especially those related to general and systemic properties of the developmental process. | Zizhang Li Wenjing Yang Peng Wu Yuyan Shan Xiaoyu Zhang Feng Chen Junnan Yang Jian-Rong Yang | 2024 | Journal of Genetics and Genomics2024，51，1： | 0 |
| 4 | A lightweight DDoS detection scheme under SDN context显示文摘Software-defined networking(SDN),a novel network paradigm,separates the control plane and data plane into dif-ferent network equipment to realize the flexible control of network traffic.Its excellent programmability and global view present many new opportunities.DDoS detection under the SDN context is an important and challenging research field.Some previous works attempted to collect and analyze statistics related to flows,usually recorded in switches,to address DDoS threats.In contrast,other works applied machine learning-based solutions to identify DDos and achieved promising results.Generally,most previous works need to periodically request flow rules or packets to obtain flow statistics or features to detect stealthy exceptions.Nevertheless,the request for flow rules is very time-consuming and CPU-consuming;moreover may congest the communication channel between the controller and the switches.Therefore,we present FORT,a lightweight DDoS detection scheme,which spreads the rule-based detection algorithm at edge switches and determines whether to start it by periodically retrieving the ports state.A time-series algorithm,ARIMA,is utilized to determine the port statistics adaptively,and an SVM algorithm is applied to detect whether a DDoS attack does occur.Representative experiments demonstrate that FORT can significantly reduce the controller load and provide a reliable detection accuracy.Referring to the false alarm rate of 1.24%in the comparison scheme,the false alarm rate of this scheme is only 0.039%,which significantly reduces the probability of false alarm.Besides,by introducing the alarm mechanism,this scheme can reduce the load of the southbound chan-nel by more than 60%in the normal state. | Kun Jia Chaoge Liu Qixu Liu Junnan Wang Jiazhi Liu Feng Liu | 2023 | Cybersecurity2023，6，1： | 0 |
| 5 | Fabric characteristics of in situ sand with/without liquefaction verified by anisotropy of magnetic susceptibility显示文摘It is well known that fabric of sand may significantly affect mechanical behaviors and liquefaction resistance of sand.Various optical techniques are currently utilized to visualize the fabric,especially the distribution of the long axis of soil particles.However,none of these methods provides an ideal solution in laboratory tests and in situ observation.In this study,anisotropy of magnetic susceptibility(AMS)was first proposed as a convenient and efficient way to evaluate the liquefaction of clean sand.At first,investigations with scanning electron microscopy(SEM)and AMS were simultaneously conducted on two groups of soil specimens with different initial fabrics to verify the feasibility of the AMS technique.Then,80 in situ samples were collected to analyze the feature of liquefied and non-liquefied sand layers through AMS tests.It is clearly known from the test results that the natural sedimentary fabric was destroyed during liquefaction and the fabric anisotropy was greatly changed after liquefaction.The feasibility of evaluating soil fabric using the AMS survey was verified by the laboratory tests.Furthermore,the applicability of AMS in detecting liquefied layer in situ was confirmed for the first time. | Xueqian Ni Junnan Ma Hide Sakaguchi Feng Zhang | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，5： | 0 |
| 6 | Correction: Aiphanol, a native compound, suppresses angiogenesis via dual-targeting VEGFR2 and COX2显示文摘Correction to:Signal Transduction and Targeted Therapy http://gffzzd3cc09b8251d45dfskxxk9oqkxqbo6o5c.ffgz.tsg.suse.edu.cn/10.1038/s41392-021-00739-5,published online 03 December 2021 After online publication of the letter1,the author found two images in the supplement materials were used incorrectly,Additionally,there is an error in the chemical structure of Aiphanol in Figs.1a and 1s that needs to be corrected.The correct data are provided as follows.The key findings of the article are not affected by these corrections.The original article has been corrected. | Shanmei Chen Junnan Feng Chuanke Zhao Lixin Wang Lin Meng Caiyun Liu Shaoqing Cai Yanxing Jia Like Qu Chengchao Shou | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 0 |
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