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| 1 | Complications in the management of metastatic spinal disease显示文摘Metastatic spine disease accounts for 10% to 30% of new cancer diagnoses annually. The most frequent presentation is axial spinal pain. No treatment has been proven to increase the life expectancy of patients with spinal metastasis. The goals of therapy are pain control and functional preservation. The most important prognostic indicator for spinal metastases is the initial functional score. Treatment is multidisciplinary, and virtually all treatment is palliative. Management is guided by three key issues; neurologic compromise, spinal instability, and individual patient factors. Site-directed radiation, with or without chemotherapy is the most commonly used treatment modality for those patients presenting with spinal pain, causative by tumours which are not impinging on neural elements. Operative intervention has, until recently been advocated for establishing a tissue diagnosis, mechanical stabilization and for reduction of tumor burden but not for a curative approach. It is treatment of choice patients with diseaseadvancement despite radiotherapy and in those with known radiotherapy-resistant tumors. Vertebral resection and ante-rior stabilization with methacrylate or hardware(e.g., cages) has been advocated.Surgical decompression and stabilization, however, along with radiotherapy, may provide the most promising treatment. It stabilizes the metastatic deposited areaand allows ambulation with pain relief. In general, patients who are nonambulatory at diagnosis do poorly, as do patients in whom more than one vertebra is involved. Surgical intervention is indicated in patients with radiation-resistant tumors, spinal instability, spinal compression with bone or disk fragments, progressive neurologic deterioration, previous radiation exposure, and uncertain diagnosis that requires tissue diagnosis. The main goal in the management of spinal metastatic deposits is always palliative rather than curative, with the primary aim being pain relief and improved mobility. This however, does not come without complications, regardless of the surgical intervention technique used. These complication range from the general surgical complications of bleeding, infection, damage to surrounding structures and post operative DT/PE to spinal specific complications of persistent neurologic deficit and paralysis. | Eilis Catherine Dunning Joseph Simon Butler Seamus Morris | 2012 | World Journal of Orthopedics2012，3，8： | 8 |
| 2 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | L. Van Zwieten S. Kimber S. Morris K. Y. Chan A. Downie J. Rust S. Joseph A. Cowie | 2010 | Plant and Soil (-)2010，，1： | 5 |
| 3 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | L. Van Zwieten S. Kimber S. Morris K. Y. Chan A. Downie J. Rust S. Joseph A. Cowie | 2010 | Plant and Soil2010，，1： | 4 |
| 4 | Factors in fluencing farmers' participation in crop intensification program in Rwanda显示文摘The crop intensification program(CIP)was introduced in Rwanda in 2007 by the Ministry of Agriculture and Animal Resources(MINAGRI),Rwanda,as a solution to the land fragmentation,low use of agricultural inputs and low access to extension services.However,due to the voluntary nature of farmers’participation and their reluctance to participate,this study aimed at assessing the factors that influence their participation.Data were collected from 340 respondents through a household survey in Mayange and Rusarabuye sectors.Descriptive statistics and binary logistic regression model were used to analyze the data.Results show that the factors that significantly influenced the farmers’participation in the CIP include gender,non-farm income,farmland size,farming experience,land acquisition means,market access,trust and agro-ecological conditions.In fact,the non-farm income significantly increased the farmers’decisions to participate in the CIP(P<0.001)as it eases the financial capital needed to invest in the CIP activities.On the land acquisition means,the farmers who inherited or bought the land positively and significantly participated in the CIP(P<0.05)because they had the land tenure security.However,the participation in the CIP was hindered by inadequate irrigation and mechanization facilities,lack of farmers’participation in the CIP planning process,inadequate extension services,inadequate agricultural inputs and inadequate post-harvest technologies.Closer collaboration between farmers,local leaders,extension agents and agricultural service providers as well as the farmers’practical skills in irrigation and mechanization could enhance the participation to the program.Therefore,there is a need on the part of policymakers to empower farmers with adequate knowledge on better cropping practices and agricultural technologies through appropriate extension services and bottom-up based program. | Alphonse Nahayo Morris O.Omondi ZHANG Xu-hui LI Lian-qing PAN Gen-xing Stephen Joseph | 2017 | Journal of Integrative Agriculture2017，16，6： | 3 |
| 5 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | L. Van Zwieten S. Kimber S. Morris K. Y. Chan A. Downie J. Rust S. Joseph A. Cowie | 2010 | Plant and Soil (-)2010，，1： | 3 |
| 6 | Regulation of Wnt/β-catenin signaling by herpesviruses显示文摘The Wnt/β-catenin signaling pathway is instrumental in successful differentiation and proliferation of mammalian cells. It is therefore not surprising that the herpesvirus family has developed mechanisms to interact with and manipulate this pathway. Successful coexistence with the host requires that herpesviruses establish a lifelong infection that includes periods of latency and reactivation or persistence. Many herpesviruses establish latency in progenitor cells and viral reactivation is linked to host-cell proliferation and differentiation status. Importantly, Wnt/β-catenin is tightly connected to stem/progenitor cell maintenance and differentiation. Numerous studies have linked Wnt/β-catenin signaling to a variety of cancers, emphasizing the importance of Wnt/β-catenin pathways in development, tissue homeostasis and disease. This review details how the alpha-, beta-, and gammaherpesviruses interact and manipulate the Wnt/β-catenin pathway to promote a virus-centric agenda. | Kevin J Zwezdaryk Joseph A Combs Cindy A Morris Deborah E Sullivan | 2016 | World Journal of Virology2016，5，4： | 2 |
| 7 | Biochar improves diary pasture yields by alleviating P and K constraints with no influence on soil respiration or N2O emissions显示文摘Dairy pastures can be a major source of soil nitrous oxide(N_(2)O)emissions due to the combination of intensive nitrogen(N)fertiliser use and high soil water content,from either rainfall and/or irrigation.Biochar application is a promising approach to lower soil greenhouse gas emissions,particularly under high soil moisture conditions where denitrification is the primary N-transformation pathway.In a replicated field trial,we evaluated the effects of two contrasting biochars derived from poul-try litter and from hardwood on soil N_(2)O emissions,soil ammonium(NH4^(+))and nitrate(NO3^(−))status,pasture productivity and herbage nutrient content.A liming treatment to mimic the liming equivalence of the poultry litter biochar was used to separate any effects observed from changes in soil pH.To further separate the effects of biochars on soil N status,N_(2)O emissions and pasture N uptake,high and low N fertiliser doses(annual application of 672 kg N ha^(−1),336 kg N ha^(−1))were superimposed across all of the treatments.The N fertiliser dose had no significant impact on pasture yield.Application of poultry litter biochar resulted in significant increases in pasture productivity under both high and low N inputs.This was achieved by alleviating soil P,and possibly K nutritional constraints that are typical in Australian Ferralsols.Under the high N fertiliser dose,emissions of N_(2)O from the treatments and control were not significantly different(p>0.05)and ranged between 1.14 and 1.78 kg N_(2)O-N ha^(−1)across the 11-month study.The low N dose resulted in significantly lower emissions of N_(2)O of between 0.80 and 0.84 kg N_(2)O-N ha^(−1),but biochar had no significant effect on net emissions across the season.The lack of impact of biochar on N_(2)O emissions was attributed to the relatively dry conditions over the trial period resulting in nitrification being the most likely N-transformation pathway.During brief episodes of high soil moisture,peak emissions from the biochar plots were lower than from the control or lime treatment,but these differences did not impact on the emis-sion budget over the 11-month sampling campaign. | Lukas van Zwieten Stephen Kimber Stephen Morris Lynne M.Macdonald Josh Rust Scott Petty Stephen Joseph Terry Rose | 2019 | Biochar2019，1，1： | 2 |
| 8 | Partial growth-hormone insensitivity: The role of growth-hormone receptor mutations in idiopathic short stature显示文摘 | Audrey D. Goddard Patrick Dowd Steven Chernausek Mitchell Geffner Joseph Gertner Raymond Hintz Nancy Hopwood Selna Kaplan Leslie Plotnick Alan Rogol Robert Rosenfield Paul Saenger Nellie Mauras Richard Hershkopf Morris Angulo Kenneth Attie | 1997 | The Journal of Pediatrics1997，，1： | 2 |
| 9 | Modelling low reynolds number incompressible flows using SPH显示文摘 | Morris Joseph P Fox Patrick J Zhu Yi | 1997 | Journal of Computational Physics1997，136，： | 1 |
| 10 | Phase II Study of Lutetium-177–Labeled Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody J591 for Metastatic Castration-Resistant Prostate Cancer显示文摘 | Scott T. Tagawa Matthew I. Milowsky Michael Morris Shankar Vallabhajosula Paul Christos Naveed H. Akhtar Joseph Osborne Stanley J. Goldsmith Steve Larson Neeta Pandit Taskar Howard I. Scher Neil H. Bander David M. Nanus | 2013 | Clinical Cancer Research2013，，18： | 1 |
| 11 | Phase I pharmacokinetic and biodistribution study with escalating doses of 223 Ra-dichloride in men with castration-resistant metastatic prostate cancer显示文摘 | Jorge A. Carrasquillo Joseph A. O’Donoghue Neeta Pandit-Taskar John L. Humm Dana E. Rathkopf Susan F. Slovin Matthew J. Williamson Kristine Lacuna Anne-Kirsti Aksnes Steven M. Larson Howard I. Scher Michael J. Morris | 2013 | European Journal of Nuclear Medicine and Molecular Imaging2013，，9： | 1 |
| 12 | Does Preoperative Patellofemoral Joint State Affect Medial Unicompartmental Arthroplasty Survival?显示文摘 | Berend Keith R. Lombardi Adolph V. Morris Michael J. Hurst Jason M. Kavolus Joseph J | 2011 | Orthopedics (Online)2011，，9： | 1 |
| 13 | Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study显示文摘 | Keith C Bible Vera J Suman Julian R Molina Robert C Smallridge William J Maples Michael E Menefee Joseph Rubin Kostandinos Sideras John C Morris Bryan McIver Jill K Burton Kevin P Webster Carolyn Bieber Anne M Traynor Patrick J Flynn Boon Cher Goh Hui Tan | 2010 | Lancet Oncology2010，，10： | 1 |
| 14 | Effect of biochar from slow pyrolysis of papermill waste on agromic performance and soil fertility显示文摘 | Van Zwieten L Kimber S Morris S Chan KY Downie A Rust J Joseph S Cowie A | 2010 | Plant and Soil2010，327，12： | 1 |
| 15 | Perioperative Myocardial Infarction显示文摘 | Giora Landesberg W Scott Beattie Morris Mosseri Allan S. Jaffe Joseph S. Alpert | 2009 | Circulation2009，，22： | 1 |
| 16 | Quality of life after kidney and pancreas transplantation:a review显示文摘 | Joseph JT Baines LS Morris MC | 2003 | Am J Kidney Dis2003，42，3： | 1 |
| 17 | Modeling low reynolds number incompressible flows using SPH显示文摘 | Joseph P Morris Patrick J Fox Zhu Y | 1997 | Journal of Computational Physics1997，136，1： | 1 |
| 18 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | L. Van Zwieten S. Kimber S. Morris K. Y. Chan A. Downie J. Rust S. Joseph A. Cowie | 2010 | Plant and Soil (-)2010，，1： | 1 |
| 19 | Gait analysis using a shoe-integrated wireless sensor system 显示文摘 | MORRIS S J JOSEPH A BENBASAT A Y | 2008 | Information Technology in Biomedicine2008，12，4： | 1 |
| 20 | Multiresistant Enterobacter sakazakii Wound Infection in an Adult显示文摘 | Shed K Dennison Joseph Morris | 2002 | Infect Meal2002，19，： | 1 |
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