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| 1 | Intentional ingestions of foreign objects among prisoners: A review显示文摘The intentional ingestion of foreign objects(IIFO) is described more commonly in prison populations than in the general population, with an estimated annual incidence of 1 in 1900 inmates in our state correctional facilities. Incidents often involve ingestion of small metal objects(e.g., paperclips, razor blades) or other commonly available items like pens or eating utensils. Despite ingestion of relatively sharp objects, most episodes can be clinically managed with either observation or endoscopy. Surgery should be reserved for those with signs or symptoms of gastrointestinal perforation or obstruction. For those with a history of IIFO, efforts should focus on prevention of recurrenceas subsequent episodes are associated with higher morbidity, significant healthcare and security costs. The pattern of IIFO is often repetitive, with escalation both in frequency of ingestions and in number of items ingested. Little is known about successful prevention strategies, but efforts to monitor patients and provide psychiatric care are potential best-practice strategies. This article aims to provide state-of-the art review on the topic, followed by a set of basic recommendations. | David C Evans Thomas R Wojda Christian D Jones Andrew J Otey Stanislaw P Stawicki | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，3： | 10 |
| 2 | 可操作性地震预报:有关“为什么”和“怎么办”的几点思考显示文摘假设研究都市区附近断层的地震学家根据经验知识以令人信服的口吻声称,未来一周内发生一次大地震的概率要比平常的一个7天周期中发生地震的概率高出100~1000倍,那么——如果采取行动的话——民众应该采取那些防御措施呢? | Thomas H Jordan Lucile M Jones 左玉玲(译) 郑需要(校) | 2010 | 国际地震动态2010，，10： | 7 |
| 3 | Gastric emptying, postprandial blood pressure, glycaemia and splanchnic flow in Parkinson's disease显示文摘AIM: To determine gastric emptying, blood pressure, mesenteric artery blood flow, and blood glucose responses to oral glucose in Parkinson's disease. METHODS: Twenty-one subjects(13 M, 8 F; age 64.2 ± 1.6 years) with mild to moderate Parkinson's disease(Hoehn and Yahr score 1.4 ± 0.1, duration of known disease 6.3 ± 0.9 years) consumed a 75 g glucose drink, labelled with 20 MBq 99mTc-calcium phytate. Gastric emptying was quantified with scintigraphy, blood pressure and heart rate with an automated device, superior mesenteric artery blood flow by Doppler ultrasonography and blood glucose byglucometer for 180 min. Autonomic nerve function was evaluated with cardiovascular reflex tests and upper gastrointestinal symptoms by questionnaire. RESULTS: The mean gastric half-emptying time was 106 ± 9.1 min, gastric emptying was abnormally delayed in 3 subjects(14%). Systolic and diastolic blood pressure fell(P < 0.001) and mesenteric blood flow and blood glucose(P < 0.001 for both) increased, following the drink. Three subjects(14%) had definite autonomic neuropathy and 8(38%) had postprandial hypotension. There were no significant relationships between changes in blood pressure, heart rate or mesenteric artery blood flow with gastric emptying. Gastric emptying was related to the score for autonomic nerve function(R = 0.55, P < 0.01). There was an inverse relationship between the blood glucose at t = 30 min(R =-0.52, P < 0.05), while the blood glucose at t = 180 min was related directly(R = 0.49, P < 0.05), with gastric emptying. CONCLUSION: In mild to moderate Parkinson's disease, gastric emptying is related to autonomic dysfunction and a determinant of the glycaemic response to oral glucose. | Laurence G Trahair Thomas E Kimber Katerina Flabouris Michael Horowitz Karen L Jones | 2016 | World Journal of Gastroenterology2016，22，20： | 5 |
| 4 | AHA/ACC Guidelines for Secondary Prevention for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2006 Update: Endorsed by the National Heart, Lung, and Blood Institute显示文摘 | Sidney C. Smith Jerilyn Allen Steven N. Blair Robert O. Bonow Lawrence M. Brass Gregg C. Fonarow Scott M. Grundy Loren Hiratzka Daniel Jones Harlan M. Krumholz Lori Mosca Richard C. Pasternak Thomas Pearson Marc A. Pfeffer Kathryn A. Taubert | 2006 | Circulation2006，，19： | 4 |
| 5 | ACC/AHA guidelines for the management of patients with unstable angina and non–st-segment elevation myocardial infarction显示文摘 | Eugene Braunwald Elliott M Antman John W Beasley Robert M Califf Melvin D Cheitlin Judith S Hochman Robert H Jones Dean Kereiakes Joel Kupersmith Thomas N Levin Carl J Pepine John W Schaeffer Earl E Smith David E Steward Pierre Theroux Raymond J Gibbons J | 2000 | Journal of the American College of Cardiology2000，，3： | 4 |
| 6 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 7 | 用分子标记研究禾本科赖草属植物可溶性碳水化合物、色素积累和生长特性之间的遗传相关性(英文)显示文摘在低温条件下 ,冷季草的可溶性碳水化合物通常与紫色素的积累、生长的缓慢性及对寒冷的适应性具有相关性。Vrn_1基因对一年生冬性禾本科物种的春化、生长和可溶性碳水化合物的积累有重要作用。本研究以Ley muscinereus×L .triticoides的杂种F1开放授粉获得的F2 群体为材料 ,用 2 0 4个未定位的AFLP分子标记和几个基因组特定的与vrn_1相连锁的DNA标记检测了控制可溶性碳水化合物的积累、紫色素的积累和生长特性等几个数量性状的QTL。根据生长特性和适应性可将Leymuscinereus和L .triticoides区分开来。研究表明可溶性碳水化合物与紫色素的积累呈正相关 ,而且有关基因对这两种性状具有多效性。与之相类似 ,分蘖、叶发育、叶生长、草被剪后的再生长和地下茎的蔓延性这些性状之间也呈正相关 ,控制这些性状的基因具有多效性。但是可溶性碳水化合物的积累与生长的缓慢性无相关性。有几个分子标记包括与vrn_Xm1邻近的一个分子标记对叶可溶性碳水化合物的浓度和低温生长具有正效应。而与vrn_Ns1邻近的一个DNA标记对分蘖具有更加特别的效应。我们推测vrn_1对多年生赖草低温下叶可溶性碳水化合物的积累及生长习性具有数量效应。发现几个DNA标记对可溶性碳水化合物的积累及多个生长特性有较强的作用。 | 胡赞民 Steven R. LARSON Thomas A. JONES Richard R-C. WANG | 2002 | Acta Botanica Sinica2002，44，10： | 3 |
| 8 | Wrist Fractures显示文摘 | Douglas P Hanel Marci D Jones Thomas E Trumble | 2002 | Orthopedic Clinics of North America2002，，1： | 3 |
| 9 | Macrophage secretory products induce an inflammatory phenotype in hepatocytes显示文摘AIM:To investigate the influence of macrophages on hepatocyte phenotype and function.METHODS:Macrophages were differentiated from THP-1 monocytes via phorbol myristate acetate stimulation and the effects of monocyte or macrophageconditioned medium on HepG2 mRNA and protein expression determined.The in vivo relevance of these findings was confirmed using liver biopsies from 147 patients with hepatitis C virus(HCV)infection.RESULTS:Conditioned media from macrophages,but not monocytes,induced a transient morphological change in hepatocytes associated with upregulation of vimentin(7.8±2.5-fold,P=0.045)and transforming growth factor(TGF)-β1(2.6±0.2-fold,P<0.001)and downregulation of epithelial cadherin(1.7±0.02-fold,P=0.017)mRNA expression.Microarray analysis revealed significant upregulation of lipocalin-2(17-fold,P <0.001)and pathways associated with inflammation,and substantial downregulation of pathways related to hepatocyte function.In patients with chronic HCV,realtime polymerase chain reaction and immunohistochemistry confirmed an increase in lipocalin-2 mRNA(F0 1.0 ±0.3,F1 2.2±0.2,F2 3.0±9.3,F3/4 4.0±0.8,P= 0.003)and protein expression(F1 1.0±0.5,F2 1.3± 0.4,F3/4 3.6±0.4,P=0.014)with increasing liver injury.High performance liquid chromatography-tandem mass spectrometry analysis identified elevated levels of matrix metalloproteinase(MMP)-9 in macrophageconditioned medium,and a chemical inhibitor of MMP-9 attenuated the change in morphology and mRNA expression of TGF-β1(2.9±0.2 vs 1.04±0.1,P<0.001) in macrophage-conditioned media treated HepG2 cells.In patients with chronic HCV infection,hepatic mRNA expression of CD163(F0 1.0±0.2,F1/2 2.8±0.3,F3/4 5.3±1.0,P=0.001)and MMP-9(F0 1.0±0.4,F1/2 2.8±0.3,F3/4 4.1±0.8,P=0.011)was significantly associated with increasing stage of fibrosis.CONCLUSION:Secreted macrophage products alter the phenotype and function of hepatocytes,with increased expression of inflammatory mediators,suggesting that hepatocytes actively participate in liver injury. | Michelle Melino Victoria L Gadd Gene V Walker Richard Skoien Helen D Barrie Dinesh Jothimani Leigh Horsfall Alun Jones Matthew J Sweet Gethin P Thomas Andrew D Clouston Julie R Jonsson Elizabeth E Powell | 2012 | World Journal of Gastroenterology2012，18，15： | 3 |
| 10 | A New Era in Esophageal Diagnostics: The Image-Based Paradigm of High-Resolution Manometry显示文摘 | Renato Salvador Attila Dubecz Marek Polomsky Oliver Gellerson Carolyn E. Jones Daniel P. Raymond Thomas J. Watson Jeffrey H. Peters | 2009 | Journal of the American College of Surgeons2009，，6： | 2 |
| 11 | Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog显示文摘 | Michael Rera Sepehr Bahadorani Jaehyoung Cho Christopher L. Koehler Matthew Ulgherait Jae H. Hur William S. Ansari Thomas Lo D. Leanne Jones David W. Walker | 2011 | Cell Metabolism2011，，5： | 2 |
| 12 | Evidence-based Guidelines From ESPGHAN and NASPGHAN for Helicobacter pylori Infection in Children显示文摘 | Sibylle Koletzko Nicola L. Jones Karen J. Goodman Benjamin Gold Marion Rowland Samy Cadranel Sonny Chong Richard B. Colletti Thomas Casswall Yoram Elitsur Jeannette Guarner Nicolas Kalach Armando Madrazo Francis Megraud Giuseppina Oderda | 2011 | Journal of Pediatric Gastroenterology and Nutrition2011，，2： | 2 |
| 13 | The world’s ten most feared fungi显示文摘An account is provided of the world’s ten most feared fungi.Within areas of interest,we have organized the entries in the order of concern.We put four human pathogens first as this is of concern to most people.This is followed by fungi producing mycotoxins that are highly harmful for humans;Aspergillus flavus,the main producer of aflatoxins,was used as an example.Problems due to indoor air fungi may also directly affect our health and we use Stachybotrys chartarum as an example.Not everyone collects and eats edible mushrooms.However,fatalities caused by mushroom intoxications often make news headlines and therefore we include one of the most poisonous of all mushrooms,Amanita phalloides,as an example.We then move on to the fungi that damage our dwellings causing serious anxiety by rotting our timber structures and flooring.Serpula lacrymans,which causes dry rot is an excellent example.The next example serves to represent all plant and forest pathogens.Here we chose Austropuccinia psidii as it is causing devastating effects in Australia and will probably do likewise in New Zealand.Finally,we chose an important amphibian pathogen which is causing serious declines in the numbers of frogs and other amphibians worldwide.Although we target the top ten most feared fungi,numerous others are causing serious concern to human health,plant production,forestry,other animals and our factories and dwellings.By highlighting ten feared fungi as an example,we aim to promote public awareness of the cost and importance of fungi. | Kevin D.Hyde Abdullah M.S.Al-Hatmi Birgitte Andersen Teun Boekhout Walter Buzina Thomas L.Dawson Jr. Dan C.Eastwood E.B.Gareth Jones Sybren de Hoog Yingqian Kang Joyce E.Longcore Eric H.C.McKenzie Jacques F.Meis Laetitia Pinson-Gadais Achala R.Rathnayaka Florence Richard-Forget Marc Stadler Bart Theelen Benjarong Thongbai Clement K.M.Tsui | 2018 | Fungal Diversity2018，，6： | 2 |
| 14 | Esophageal eosinophilia with dysphagia显示文摘 | Stephen E. A. Attwood Thomas C. Smyrk Tom R. Demeester James B. Jones | 1993 | Digestive Diseases and Sciences1993，，： | 2 |
| 15 | Photogrammetric techniques for aerospace applications显示文摘 | Tianshu Liu Alpheus W. Burner Thomas W. Jones Danny A. Barrows | 2012 | Progress in Aerospace Sciences2012，，： | 2 |
| 16 | Intravenous anti–IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis显示文摘 | Marc E. Rothenberg Ting Wen Allison Greenberg Oral Alpan Benjamin Enav Ikuo Hirano Kari Nadeau Sergio Kaiser Thomas Peters Antonio Perez Ieuan Jones Jonathan P. Arm Robert M. Strieter Ronald Sabo Kulasiri A. Gunawardena | 2015 | The Journal of Allergy and Clinical Immunology2015，，： | 2 |
| 17 | Auxin Binding Protein 1 Reinforces Resistance to Sugarcane Mosaic Virus in Maize显示文摘 | Pengfei Leng Qing Ji Torben Asp Ursula K. Frei Christina R. Ingvardsen Yongzhong Xing Bruno Studer Margaret Redinbaugh Mark Jones Priyanka Gajjar Sisi Liu Fei Li Guangtang Pan Mingliang Xu Thomas Lǖbberstedt | 2017 | Molecular Plant2017，10，10： | 2 |
| 18 | Hyaluronic acid and its effect on postoperative adhesion in the rabit flexion tendon显示文摘 | Thomas S Jones LC Hungerford DS | 1986 | Clin Orthop1986，206，： | 1 |
| 19 | Validation of real-time three-dimensional echocardiography for quantifying left ventricular volumes in the presence of a left ventricular aneurysm: in vitro and in vivo studies显示文摘 | Jian Xin Qin Michael Jones Takahiro Shiota Neil L Greenberg Hiroyuki Tsujino Michael S Firstenberg Pankaj C Gupta Arthur D Zetts Yong Xu Jing Ping Sun Lisa A Cardon Jill A Odabashian Scott D Flamm Richard D White Julio A Panza James D Thomas | 2000 | Journal of the American College of Cardiology2000，，3： | 1 |
| 20 | Resistant Hypertension: Diagnosis, Evaluation, and Treatment: A Scientific Statement From the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research显示文摘 | David A. Calhoun Daniel Jones Stephen Textor David C. Goff Timothy P. Murphy Robert D. Toto Anthony White William C. Cushman William White Domenic Sica Keith Ferdinand Thomas D. Giles Bonita Falkner Robert M. Carey | 2008 | Hypertension2008，，6： | 1 |
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