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| 1 | 快速煅烧分解石灰石对其吸收CO_2和SO_2的影响显示文摘在加热过程中,应用一种新型的快速加热装置——铂膜反应器,及时准确地获得样品质量和颗粒温度,来研究石灰石的煅烧分解,并对石灰石加热速率高达750℃/s下的分解反应特性,及其对分解后产生的氧化钙吸收CO2和脱硫的化学反应特性进行了研究.实验表明,在初始加热阶段,高升温速率明显阻碍了煅烧分解的进行,这对分解后的CaO吸收CO2的效果影响不大.当加热速率升高时,石灰石分解后产生的CaO吸收CO2和脱硫过程中,钙利用率显著下降. | 阎常峰 陈勇 Grace John R Lim Jim | 2007 | 燃烧科学与技术2007，13，1： | 7 |
| 2 | Proton pump inhibitor use increases mortality and hepatic decompensation in liver cirrhosis显示文摘BACKGROUND Proton pump inhibitors(PPIs)are widely prescribed,often without clear indications.There are conflicting data on its association with mortality risk and hepatic decompensation in cirrhotic patients.Furthermore,PPI users and PPI exposure in some studies have been poorly defined with many confounding factors.AIM To examine if PPI use increases mortality and hepatic decompensation and the impact of cumulative PPI dose exposure.METHODS Data from patients with decompensated liver cirrhosis were extracted from a hospital database between 2013 to 2017.PPI users were defined as cumulative defined daily dose(cDDD)≥28 within a landmark period,after hospitalisation for hepatic decompensation.Cox regression analysis for comparison was done after propensity score adjustment.Further risk of hepatic decompensation was analysed by Poisson regression.RESULTS Among 295 decompensated cirrhosis patients,238 were PPI users and 57 were non-users.PPI users had higher mortality compared to non-users[adjusted HR=2.10,(1.20-3.67);P=0.009].Longer PPI use with cDDD>90 was associated with higher mortality,compared to non-users[aHR=2.27,(1.10-5.14);P=0.038].PPI users had a higher incidence of hospitalization for hepatic decompensation[aRR=1.61,(1.30-2.11);P<0.001].CONCLUSION PPI use in decompensated cirrhosis is associated with increased risk of mortality and hepatic decompensation.Longer PPI exposure with cDDD>90 increases the risk of mortality. | Marianne Anastasia De Roza Lim Kai Jia Wen Kam Yiong Huak Chan Andrew Kwek Tiing Leong Ang John Chen Hsiang | 2019 | World Journal of Gastroenterology2019，25，33： | 6 |
| 3 | Dynamic Force Reduction and Heat Transfer Improvement for Horizontal Tubes in Large-Particle Gas-Fluidized Beds显示文摘力量和热转移上的试管银行配置的效果为二维、三维的煤气的使流体化的床被调查。有效动态力量和热转移系数为几种试管银行配置被测量,并且平均力量比为一个单个试管小,这被发现。热转移系数能被提供足够的空间让粒子在试管银行的双方附近下降增加。结果为优化试管银行的配置当由于动态力量减少试管侵蚀时,完成高热转移系数提供有用指南。 | Yusumi Nagahashi John R.Grace Kok-Seng Lim Yutaka Asako | 2008 | Journal of Thermal Science2008，17，1： | 4 |
| 4 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | 2012 (9859)2012，，9859： | 3 |
| 5 | Proteomic and genomic studies of non-alcoholic fatty liver disease-clues in the pathogenesis显示文摘Non-alcoholic fatty liver disease(NAFLD)is a widely prevalent hepatic disorder that covers wide spectrum of liver pathology.NAFLD is strongly associated with liver inflammation,metabolic hyperlipidaemia and insulin resistance.Frequently,NAFLD has been considered as the hepatic manifestation of metabolic syndrome.The pathophysiology of NAFLD has not been fully elucidated.Some patients can remain in the stage of simple steatosis,which generally is a benign condition;whereas others can develop liver inflammation and progress into non-alcoholic steatohepatitis,fibrosis,cirrhosis and hepatocellular carcinoma.The mechanism behind the progression is still not fully understood.Much ongoing proteomic researches have focused on discovering the unbiased circulating biochemical markers to allow early detection and treatment of NAFLD.Comprehensive genomic studies have also begun to provide new insights into the gene polymorphism to understand patientdisease variations.Therefore,NAFLD is considered a complex and mutifactorial disease phenotype resulting from environmental exposures acting on a susceptible polygenic background.This paper reviewed the current status of proteomic and genomic studies that have contributed to the understanding of NAFLD pathogenesis.For proteomics section,this review highlighted functional proteins that involved in:(1)transportation;(2)metabolic pathway;(3)acute phase reaction;(4)antiinflammatory;(5)extracellular matrix;and(6)immune system.In the genomic studies,this review will discuss genes which involved in:(1)lipolysis;(2)adipokines;and(3)cytokines production. | Jun Wei Lim John Dillon Michael Miller | 2014 | World Journal of Gastroenterology2014，20，26： | 3 |
| 6 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet2012，，9859： | 2 |
| 7 | Metabolic positron emission tomography imaging of cancer:Pairing lipid metabolism with glycolysis显示文摘The limitations of fluorine-18 fluorodeoxy-D-glucose(FDG)in detecting some cancers has prompted a longstandin search for other positron emission tomography(PET tracers to complement the imaging of glycolysis i oncology, with much attention paid to lipogenesis base on observations that the production of various lipid an lipid-containing compounds is increased in most cancers Radiolabeled analogs of choline and acetate have now been used as oncologic PET probes for over a decade showing convincingly improved detection sensitivit over FDG for certain cancers. However, neither cholin nor acetate have been thoroughly validated as lipogeni biomarkers, and while acetyl-Co A produced from acetat is used in de-novo lipogenesis to synthesize fatty acids acetate is also consumed by various other syntheti and metabolic pathways, with recent experimenta observations challenging the assumption that lipogenesi is its predominant role in all cancers. Since tumor detected by acetate PET are also frequently detected b choline PET, imaging of choline metabolism might serv as an alternative albeit indirect marker of lipogenesis particularly if the fatty acids produced in cancer cell are mainly destined for membrane synthesis throug incorporation into phosphatidylcholines. Aerobic glycolysi may or may not coincide with changes in lipid metabolism resulting in combinatorial metabolic phenotypes that ma have different prognostic or therapeutic implications Consequently, PET imaging using dual metabolic tracers in addition to being diagnostically superior to imagin with individual tracers, could eventually play a greate role in supporting precision medicine, as efforts t develop small-molecule metabolic pathway inhibitors ar coming to fruition. To prepare for this advent, clinical an translational studies of metabolic PET tracers must g beyond simply estimating tracer diagnostic utility, and aim to uncover potential therapeutic avenues associated wit these metabolic alterations. | Sandi A Kwee John Lim | 2016 | World Journal of Radiology2016，8，11： | 2 |
| 8 | Inhaled Corticosteroids increase interleukin-10 hut reduce macrophage inflammatory protein-1 alpha, granulocyte-macronphage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma 显示文摘 | John M Lim S Seybold J | 1998 | Am J Respir Crit Care Med1998，157，1： | 1 |
| 9 | A new HPV-DNA test for cervical-cancer screening in developing regions: a cross-sectional study of clinical accuracy in rural China显示文摘 | You-lin Qiao John W Sellors Paul S Eder Yan-ping Bao Jeanette M Lim Fang-hui Zhao Bernhard Weigl Wen-hua Zhang Roger B Peck Ling Li Feng Chen Qing-jing Pan Attila T Lorincz | 2008 | Lancet Oncology2008，，10： | 1 |
| 10 | The effects of ecologically determined spatial complexity on the classification accuracy of simulated coral reef images显示文摘 | Alan Lim John D. Hedley Ellsworth LeDrew Peter J. Mumby Chris Roelfsema | 2009 | Remote Sensing of Environment2009，，5： | 1 |
| 11 | Preparation of thin Pd-based composite membraneon planar metallic substrate Part I: Pre-treatment of porous stainless steel substrate 显示文摘 | Li Anwu John R Grace C Jim Lim | 2007 | Journal of Membrane Science2007，298，： | 1 |
| 12 | CYBERKNIFE RADIOSURGERY FOR TRIGEMINAL NEURALGIA TREATMENT: A PRELIMINARY MULTICENTER EXPERIENCE显示文摘 | Alan T. Villavicencio Michael Lim Sigita Burneikiene Pantaleo Romanelli John R. Adler Lee McNeely Steven D. Chang Laura Fariselli Melinda McIntyre Regina Bower Giovanni Broggi Jeffrey J. Thramann | 2008 | Neurosurgery2008，，3： | 1 |
| 13 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet . 2012 (9859)2012，，9859： | 1 |
| 14 | Taxonomic revisionofthegenus Lactarius(Russulales,Basidiomycota)in Korea显示文摘The genus Lactarius Pers.(Russulales)is a cosmopolitan group of Basidiomycota that forms ectomycorrhizal relationships primarily with both deciduous and coniferous trees.Although the genus has been well-studied in Europe and North America,only fragmentary researches have been carried out on Asian species.In particular,the distribution of Lactarius species in South Korea is poorly understood due to insufficient morphological descriptions and a lack of DNA sequence data.In addition,the misuse of European and North American names has added to confusion regarding the taxonomy of Asian Lactarius species.In this study,the diversity of Lactarius in South Korea was evaluated by employing both morphological and phylogenetic approaches.A multi-locus phylogenetic analysis of 729 Lactarius specimens collected between 1960 and 2017 was performed using the internal transcribed spacer(ITS)region,partial nuclear ribosomal large subunit(nrLSU),partial second largest subunit of RNA polymerase II(rpb2),and minichromosome maintenance complex component 7(mcm7).49 Lactarius species were identified in three Lactarius subgenera:L.subg.Russularia(17 spp.),L.subg.Lactarius(22 spp.),and L.subg.Plinthogalus(10 spp.).Among them,28 Lactarius species were identified as new to science,while just 17 were previously described Lactarius species.Four of the taxa remain un-named due to paucity of materials.A key to Korean Lactarius species,molecular phylogenies,a summary of diversity,and detailed description are provided. | Hyun Lee Komsit Wissitrassameewong Myung Soo Park Annemieke Verbeken John Eimes Young Woon Lim | 2019 | Fungal Diversity2019，，2： | 1 |
| 15 | Time-interleaved oversampling A/D conversion 显示文摘 | Khoini-Poorfard R Lim L B Johns D A | 1997 | IEEE Trans Circ Syst Ⅱ1997，44，5： | 1 |
| 16 | Bacterial antimutagenesis by hydroxycinnamic acids from plant cell walls显示文摘 | Lynnette R. Ferguson Isabel Fong Lim Amira E. Pearson John Ralph Philip J. Harris | 2003 | MutRes-Genetic Toxicology and Environmental Mutagenesis2003，，1： | 1 |
| 17 | Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes显示文摘 | Xin Yuan Dawn Waterworth John R.B. Perry Noha Lim Kijoung Song John C. Chambers Weihua Zhang Peter Vollenweider Heide Stirnadel Toby Johnson Sven Bergmann Noam D. Beckmann Yun Li Luigi Ferrucci David Melzer Dena Hernandez Andrew Singleton James Scott Paul | 2008 | The American Journal of Human Genetics2008，，4： | 1 |
| 18 | An observational study suggesting clinical benefit for adjuvant postoperative chemoradiation in a population of over 500 cases after gastric resection with D2 nodal dissection for adenocarcinoma of the stomach显示文摘 | Sung Kim Do Hoon Lim Jeeyun Lee Won Ki Kang John S. MacDonald Chan Hyung Park Se Hoon Park Se-Hoon Lee Kihyun Kim Joon Oh Park Won Seog Kim Chul Won Jung Young Suk Park Young-Hyuck Im Tae Sung Sohn Jae Hyung Noh Jin Seok Heo Yong Il Kim Chul Keun Park Keu | 2005 | International Journal of Radiation Oncology Biology Physics2005，，5： | 1 |
| 19 | Estimating Relative Camera Motion from the Antipodal-Epipolar Constraint 显示文摘 | John Lim Nick Barnes LI Hong-dong | 2010 | IEEE Trans on Patter Analysis and Machine Intelligence2010，32，10： | 1 |
| 20 | BAI 3, CDX 2 and VIL 1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas显示文摘 | Muhammad F Bari Helen Brown Andrew G Nicholson Keith M Kerr John R Gosney William A Wallace Irshad Soomro Salli Muller Danielle Peat Jonathan D Moore Lesley A Ward Maxim B Freidin Eric Lim Manu Vatish David R J Snead | 2014 | Histopathology2014，，： | 1 |
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