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| 1 | Serum thymosin β4 levels in patients with hepatitis B virus-related liver failure显示文摘AIM:To investigate whether serum thymosinβ4 can provide diagnostic or prognostic information in liver failure patients caused by chronic hepatitis B virus(HBV) infection. METHODS:Serum thymosinβ4 levels were measured in 30 patients with acute-on-chronic liver failure(ACLF), 31 patients with chronic liver failure(CLF),30 patients with compensated liver cirrhosis(CR)and 32 patients with chronic hepatitis B and 30 healthy controls.Serum thymosinβ4 levels were measured by enzyme-linked immunosorbent assay and Child-Pugh and model for end-stage liver disease(MELD)scores were calculated for each patient on admission.RESULTS:Compared with healthy controls,serum thymosinβ4 levels in ACLF,CLF,CR and chronic hepatitis B patients were significantly lower,6.5047 (4.7879-10.5314)μg/mL vs 0.4632(0.2759-0.8768) μg/mL,0.6981(0.5209-1.2008)μg/mL,1.8053 (0.8110-2.3397)μg/mL,3.7803(1.8570-6.4722)μg/mL, respectively(P<0.001).The levels of thymosinβ4 in liver failure(ACLF or CLF)patients were markedly lower than that in CR(P<0.001),and a difference was also found between CLF and ACLF patients(P=0.038).In patients with chronic liver disease,there was a positive relationship between thymosinβ4 levels and albumin, choline esterase,and platelet(P<0.001),and negative relationship with alanine aminotransferase(P=0.020), aspartate aminotransferase,total bilirubin,international normalized ratio of prothrombin time,and Child-Pugh and MELD scores(P<0.001).Of the 61 liver failure patients,the thymosinβ4 levels of non-survivors were significantly lower than that of survivors(P=0.007). Receiver operating characteristics analysis identified a thymosinβ4 cutoff level of 0.5708μg/mL for predicting poor prognosis in all liver failure patients.The serial thymosinβ4 values were observed in 13 liver failure inpatients.Lower initial values were observed in the death.While greater improvement in thymosinβ4 value was found in those who recovered from the disease. CONCLUSION:Serum thymosinβ4 can be used as an important potential predictor for liver failure caused by chronic HBV infection. | Tao Han,Ying Liu,Huan Liu,Zheng-Yan Zhu,Yan Li,Shi-Xiang Xiao,Zhen Guo,Zhen-Gang Zhao,Department of Hepatology,Tianjin Institute of Hepatobiliary Disease,Tianjin Key Laboratory of Artificial Cells,Tianjin Third Central Hospital,Tianjin Medical University,83 Jintang Road,Tianjin 300170, China | 2010 | World Journal of Gastroenterology2010，16，5： | 20 |
| 2 | Response gene to complement 32 (RGC-32) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4显示文摘补充 32 的反应基因(RGC-32 ) 是涉及房间的增长,区别和迁居的一个房间周期管理者并且也在 angiogenesis 被含有。这里,我们证明在巨噬细胞的那 RGC-32 表情被 IL-4 导致并且由 LPS 减少了,显示在 RGC-32 表示和 M2 极化之间的一个连接。我们证明 RGC-32 的增加的表示或者激活的巨噬细胞,这蛋白质在压制支持 inflammatory cytokine IL-6 的生产并且支持反煽动性的调停人 TGF-β 的生产是特征的;。与一致在 vitro,数据, RGC-32 高级的联系肿瘤的巨噬细胞(TAM ) 快车,和这个表达式被导出肿瘤的腹水的液体以一种 M-CSF- 或 IL-4-dependent 方式导致。一起,这些结果为 M2 巨噬细胞极化作为一个标记建立 RGC-32 并且显示这蛋白质是为癌症免疫疗法的一个潜在的目标,指向联系肿瘤的巨噬细胞。 | Peng Zhao Daiqing Gao Qingjie Wang Bingfeng Song Qianqian Shao Jintang Sun Chunyan Ji Xingang Li Peng Li Xun Qu | 2015 | Cellular & Molecular Immunology2015，12，6： | 12 |
| 3 | Human trophoblast cells induced MDSCs from peripheral blood CD14+ myelomonocytic cells via elevated levels of CCL2显示文摘 | Yun Zhang Daiwei Qu Jintang Sun Lei Zhao Qingjie Wang Qianqian Shao Beihua Kong Xun Qu | 2016 | Cellular & Molecular Immunology2016，13，5： | 7 |
| 4 | Spherical foam growth in Al alloy melt显示文摘Due to the demand of high-tech Al alloy foam with spherical pores, high strength and high energy-absorption capacity has become one of the research foci. The aim of this study is to ascertain the growth regularity of spherical foam in Al alloy melt. Three-dimensional packing model such as face-centered cubic is established to study the spherical foam growth. Theoretical results are compared with experimental ones, and the face-centered cubic model corresponds well with the experiment. It is reasonable to assume that the pores have the same radius, the total pore number keeps unchanged and spherical foam grows with face-centered cubic packing mode. This study presents a useful help to control the average pore radius and film thickness. | SHANG Jintang HE Deping | 2005 | Science China Chemistry2005，48，3： | 6 |
| 5 | The two steps thermal decomposition of titanium hydride and two steps foaming of Al alloy显示文摘Two steps foaming (TSF) technique was proposed to prepare shaped Al alloy foam. Based on the thermal decomposition kinetics equation of titanium hydride, the relationship be-tween two steps thermal decomposition kinetics of titanium hydride and two steps foaming Al alloy melt was studied. Two steps thermal decomposition curve of titanium hydride under in-creasing and constant temperature was calculated respectively. The hydrogen mass needed in the second foaming step was also calculated. Results showed that the hydrogen mass of the second thermal decomposition of titanium hydride is enough for the second foaming step in the condition of as-received Al melt foaming. Experimental and theoretical results indicate that two steps foaming technique can be used to prepare Al alloy foam with high porosity, shaped com-ponents and sandwich with Al alloy foam core. | SHANG Jintang HE Deping | 2005 | Science China Chemistry2005，48，6： | 6 |
| 6 | Novel Ag@Nitrogen-doped Porous Carbon Composite with High Electrochemical Performance as Anode Materials for Lithium-ion Batteries显示文摘A novel Ag@nitrogen-doped porous carbon(Ag-NPC) composite was synthesized via a facile hydrothermal method and applied as an anode material in lithium-ion batteries(LIBs). Using this method, Ag nanoparticles(Ag NPs) were embedded in NPC through thermal decomposition of Ag NO_3 in the pores of NPC. The reversible capacity of Ag-NPC remained at 852 m Ah g^(-1)after 200 cycles at a current density of 0.1 A g^(-1), showing its remarkable cycling stability. The enhancement of the electrochemical properties such as cycling performance,reversible capacity and rate performance of Ag-NPC compared to the NPC contributed to the synergistic effects between Ag NPs and NPC. | Yuqing Chen Jintang Li Guanghui Yue Xuetao Luo | 2017 | Nano-Micro Letters2017，9，3： | 5 |
| 7 | The study of migration of bone mesenchymal stem cells transplanted in intervertebral discs of rabbits and expression of exogenous gene显示文摘Objective: To explore the survival and migration of bone mesenchymal stem cells transplantated in intervertebral disc of rabbits and expression of the exogenic genes. Methods: Thirty-two rabbits were used, A randomized block design was used and discs in the same rabbit were one block,the lumbar discs from L2-3 to L5-6 were randomly divided into blank group, saline group, cell transplantation groupⅠ and cell transplantation groupⅡ. The fluorescence microscopy was used to determine the fluorescence of the maker protein GFP and DNA-PCR was used to analyze the copies of DNA of neomycin-resistant gene at 1, 3, 6, months after transplantation. Results: There was fluorescence in cell transplantation group Ⅰand Ⅱ and none in blank group, saline group at 1, 3, 6 months after transplantation. In cell transplantation groups,the fluorescent distribution was more scatter with time, but no significant difference between cell groups Ⅰand Ⅱ. The test of neomycin resistant gene expressed in cell transplantation group ⅠandⅡ and quantitative analysis showed that there was no significant difference between the cell groups Ⅰand Ⅱ(P > 0.05). Conclusion: The transplanted bone mesenchymal stem cells can survive, migrate and the transfer genes can express efficiently, it suggests that the BMSC therapy may be effective to prevent and treat intervertebral disc degeneration. | Jintang Wang Hong Zhang Yingang Zhang Xiaowei Zhang Meng Li | 2006 | Journal of Nanjing Medical University2006，20，5： | 4 |
| 8 | Novel Co_3O_4 Nanoparticles/Nitrogen-Doped Carbon Composites with Extraordinary Catalytic Activity for Oxygen Evolution Reaction(OER)显示文摘Herein, Co_3O_4 nanoparticles/nitrogen-doped carbon(Co_3O_4/NPC) composites with different structures were prepared via a facile method. Structure control was achieved by the rational morphology design of ZIF-67 precursors, which were then pyrolyzed in air to obtain Co_3O_4/NPC composites. When applied as catalysts for the oxygen evolution reaction(OER), the M-Co_3O_4/NPC composites derived from the flower-like ZIF-67 showedsuperior catalytic activities than those derived from the rhombic dodecahedron and hollow spherical ZIF-67. The former M-Co_3O_4/NPC composite displayed a small overpotential of 0.3 V, low onset potential of 1.41 V, small Tafel slope of 83 m V dec^(-1), and a desirable stability.(94.7% OER activity was retained after 10 h.) The excellent performance of the flower-like M-Co_3O_4/NPC composite in the OER was attributed to its favorable structure. | Xiaobing Yang Juan Chen Yuqing Chen Pingjing Feng Huixian Lai Jintang Li Xuetao Luo | 2018 | Nano-Micro Letters2018，10，1： | 4 |
| 9 | Role of silicon in steels on galvanized coatings显示文摘In this article,five kinds of silicon-containing steel sheets have been electrodeposited,and then immersed in a pure molten zinc bath at 450 °C for various periods of time.The results by scanning electron microscopy(SEM) show that the coating of the sam-ple(0.09 wt pct Si) with iron-electrodeposited pretreatment eliminates the reactive zones which are found in the coating without iron-electrodeposited pretreatment.The galvanized sample(0.28 wt pct Si) with iron-electrodeposited pretreatment exhibits a compact and coherent coating.The coating of the sample(0.37 wt pct Si) with the iron-electrodeposited pretreatment experiences a transition from a compact and coherent coating to a reactive one.The energy dispersive spectrum(EDS) results reveal that for the galvanized samples with iron-electrodeposited pretreatment,ex-cessive silicon accumulates on the surface of the substrate due to the low solubility of silicon in the Γ,after the iron layer is depleted by the increasing growth of the Fe-Zn intermetallics.With the movement of the substrate/Γ interface toward the substrate,silicon-enriched α-Fe peels off from the substrate and breaks into the particles.The particles move toward the δ layer through the Γ layer because silicon-enriched α-Fe cannot be absorbed in the Γ layer.When the particles reach the δ/Γ interface,they are dissolved in the δ layer,making the Γ layer thin or even vanish. | Chunshan CHE Jintang LU Gang KONG Qiaoyu XU | 2009 | Acta Metallurgica Sinica(English Letters)2009，22，2： | 3 |
| 10 | Self-healing Performance of Composite Coatings Prepared by Phosphating and Cerium Nitrate Post-sealing显示文摘The phosphated and cerium nitrate post-sealed galvanized steel was firstly scratched to expose zinc layer and then placed in neutral salt spray(NSS) chamber for different durations. The microstructure and compositions of the scratches were investigated using SEM and EDS. The phases of the corrosion products were examined through XRD. The self-healing mechanism of the composite coatings was discussed. The experimental results show that the composite coatings have an excellent corrosion resistance. The corrosion products increase with corrosion time and finally cover the whole scratch. They contain phosphorous, cerium, oxygen, chloride and zinc, and are fine needle and exceedingly compact. The composite coatings are favorable self-healing. During corrosion, the self-healing ions such as Ce3+, Ce4+, PO3-+4, Zn2 in the composite coatings were dissolved, migrated, recombined, and covered the exposed zinc, impeding zinc corrosion. The self-healing process of the scratches on the composite coatings can be divided into three stages, about 2 h, 4 h, and 24 h, respectively. | 林碧兰 LU Jintang | 2015 | Journal of Wuhan University of Technology(Materials Science)2015，30，4： | 3 |
| 11 | Hypoxia induces T-cell apoptosis by inhibiting chemokine C receptor 7 expression:the role of adenosine receptor A2显示文摘Hypoxia is a major characteristic of the tumor microenvironment,and its effects on immune cells are proposed to be important factors for the process of tumor immune escape.It has been reported that hypoxia affects the function of dendritic cells and the antitumor function of T cells.Here we discuss the effects of hypoxia on T-cell survival.Our results showed that hypoxia induced apoptosis of T cells.Adenosine and adenosine receptors(AR)are important to the hypoxia-related signaling pathway.Using AR agonists and antagonists,we demonstrated that hypoxia-induced apoptosis of T cells was mediated by A^(2a)and A^(2b)receptors.Furthermore,we are the first,to our knowledge,to report that hypoxia significantly inhibited the expression of chemokine C receptor 7(CCR7)of T cells via the A^(2)R signal pathway,perhaps representing a mechanism of hypoxia-induced apoptosis of T cells.Collectively,our research demonstrated that hypoxia induces T-cell apoptosis by the A^(2)R signaling pathway partly by suppressing CCR7.Blocking the A^(2)R signaling pathway and/or activation of CCR7 can increase the anti-apoptosis function of T cells and may become a new strategy to improve antitumor potential. | Jintang Sun Yan Zhang Meixiang Yang Yun Zhang Qi Xie Zewu Li Zhaogang Dong Yongmei Yang Biping Deng Alei Feng Weixu Hu Haiting Mao Xun Qu | 2010 | Cellular & Molecular Immunology2010，7，1： | 3 |
| 12 | Uncertainty analysis of cross-calibration for HJ-1 CCD camera显示文摘Radiometric calibration of sensor is the basis of quantitative remote sensing,and uncertainty analysis is critical to ensure the accuracy of cross-calibration.Therefore,firstly,cross-calibration formulas were improved by redefining calibration coefficient and spectral band matching factor.In these formulas,cci was redefined as the calibration coefficient of normalized apparent reflectance,and spectral band matching factor as the ratio of normalized apparent reflectance.Secondly,based on the contrast of ideal and actual conditions in cross-calibration,8 sources of cross-calibration uncertainty were proposed:calibration uncertainty of standard sensor;pixel matching uncertainty;spectral band matching factor uncertainty caused by site altitude setting error,atmospheric parameters setting error,surface spectrum source,surface bidirectional reflectance characteristic,and error of atmospheric radiative transfer model;and uncertainty caused by other factors which were not considered.Finally,the contribution of each uncertainty was further analyzed and discussed for the HJ-1 CCD camera.The results provide many valuable references for evaluating the feasibility of alternative cross-calibration measurements. | WANG Zuo XIAO PengFeng GU XingFa FENG XueZhi LI XiaoYing GAO HaiLiang LI Hui LIN JinTang ZHANG XueLiang | 2013 | Chinese Science Bulletin2013，58，7： | 3 |
| 13 | Overview of Chinese research on senile dementia in mainland China显示文摘 | Yuetao Song Jintang Wang | 2010 | Ageing Research Reviews2010，，： | 3 |
| 14 | Heterogeneous ZnO@CF structures and their excellent microwave absorbing properties with thin thickness and low filling显示文摘With the aim to obtain enhanced absorbing performance at small thickness and low filling,a robust strat-egy to fabricate zinc oxide(ZnO)modified carbon fiber(CF)structures have been successfully prepared by using low temperature hydrothermal method.Due to the multi-interface polarization caused by the high specific surface area of the complex heterostructures and the improvement of impedance matching,the composites show excellent electromagnetic wave absorption properties.Under the condition of low filling content(20 wt%)and ultra-thin thickness(1.5 mm),the excellent absorption performance of minimal reflection loss of−34.4 dB and an effective absorption bandwidth(RL≤−10 dB)of 4.94 GHz is achieved.In addition,the effective absorption bandwidth covers the whole 2-18 GHz band with the increase of thickness from 0.5 to 10 mm.This work provides an innovative method for designing the matching layer of carbon-based absorbing materials,and ZnO@CF heterostructure is expected to become a potential absorbing material. | Zibao Jiao Wenjun Huyan Junru Yao Zhengjun Yao Jintang Zhou Peijiang Liu | 2022 | Journal of Materials Science & Technology2022，，18： | 2 |
| 15 | Osteopontin splice variants expressed by breast tumors regulate monocyte activation via MCP-1 and TGF-β1显示文摘Osteopontin (OPN ) ,多功能的 glycoprotein,有在 vitro 在肿瘤有不同角色的三个抄本。OPN 抄本是否在 vivo 在肿瘤进程有不同函数,是不清楚的。有免疫力的导出房间的 OPN 能支持肿瘤形成,这被报导了。我们建议导出肿瘤的 OPN 可以便于的一个假设由影响有免疫力的房间区别和功能的肿瘤免疫者逃跑。在这研究,我们构造了 OPN 抄本和 transfected 的 lentiviral 表示向量他们进 MCF-7 房间线。有 OPN 抄本的 MCF-7 房间 transfected 被注入裸体老鼠的腋窝,并且肿瘤生长被监视。结果证明所有 OPN 抄本支持了本地肿瘤形成,而是那在抄本之中没有重要差别。我们也调查了 coculturing 单核白血球肿瘤房间与肿瘤上层清液在单核白血球区别上表示的 OPN 的效果。我们与 OPN 相比发现 OPN-c upregulated CD163 层次 --and OPN-b;然而,任何一个都没抄本影响 HLA 医生和 CD206 层次。所有 OPN 抄本显著地禁止了 TNF-α并且由单核白血球提高了 IL-10 生产。而且,我们发现了 OPN 抄本的 overexpression 显著地 upregulated TGF-β 1 并且由肿瘤房间的 MCP-1 生产。用抵销抗体和 recombinant cytokines,我们发现由肿瘤房间的 OPN overexpressed 调整 TNF-α 的生产;并且由单核白血球的 IL-10 部分经由 MCP-1 和 TGF-β 1 分别地。一起,我们的结果证明 OPN 抄本没在 vivo 在乳癌形成有不同角色。我们也证明 OPN 经由 TGF-β 调整单核白血球的其他的激活; 1 并且 MCP-1,它可以为肿瘤代表另外的机制免疫者逃跑。 | Jintang Sun Alei Feng Songyu Chen Yun Zhang Qi Xie Meixiang Yang Qianqian Shao Jia Liu Qifeng Yang Beihua Kong Xun Qu | 2013 | Cellular & Molecular Immunology2013，10，2： | 2 |
| 16 | Exploratory Application of X-ray Photography in the Diagnosis of Poultry Fatty Liver显示文摘[Objectives]This study was conducted to explore the application value of X ray in the diagnosis of poultry fatty liver.[Methods]Serum biochemical tests were performed on laying hens with suspected fatty liver.The X-ray liver images of the left lateral position were observed.And the liver traits were observed by anatomy.[Results]The increase in liver space occupying lesion observed by X-ray photography was consistent with the increase in liver volume observed by anatomy.The biochemical test showed slight liver function abnormalities.[Conclusions]X-ray examination can be used for the auxiliary diagnosis of poultry fatty liver. | Yiqi ZHANG Jiao LI Jintang LUO Dongxu WANG Yuanqing ZHONG Yihao ZHANG Suohua ZHAO | 2019 | Agricultural Biotechnology2019，8，4： | 2 |
| 17 | Improving the Performance of Oilwell Cement by Graft-modifi ed PB Latex显示文摘Graft-modified polybutadiene(PB) latex was synthesized and used as an admixture to improve the performance of oilwell cement. Results showed that the addition of latex to pure cement slurry can significantly reduce the fluid loss of the cement slurry. When the dosage was 8%, the fluid loss was only 38 mL, and the fluidity of the cement slurry was improved. With an increasing amount of latex, the fluidity of the cement slurry increased continuously. The toughness of cement was significantly enhanced, whose average elastic modulus was 4.2 GPa. Scanning electron microscopy revealed that the filter cake of the cement slurry with latex was thin and dense, and the surface was coated with a layer of latex film. The microstructure of the cement stone showed a high density, and an interweaving mesh network formed in the cement. The results of cement hydration heat analysis and X-ray diffraction showed that latex inhibited the hydration of cement; the effect was stronger under a larger amount of latex. It is indicated that the graft-modified PB latex has great potential to replace the conventional styrene-butadiene rubber(SBR) latex for cementing in the future. | Jintang Guo Wenjie Pan Jinjie Fan Yongjin Yu | 2018 | Transactions of Tianjin University2018，24，5： | 2 |
| 18 | CD90 is Identified as a Candidate Marker for Cancer Stem Cells in Primary High-Grade Gliomas Using Tissue Microarrays显示文摘 | Jintang He Yashu Liu Thant Zhu Jianhui Zhu Francesco DiMeco Angelo L. Vescovi Jason A. Heth Karin M. Muraszko Xing Fan David M. Lubman | 2012 | Molecular & Cellular Proteomics2012，，6： | 1 |
| 19 | Biodegradable polydepsipeptides显示文摘 | YAKAI FENG JINTANG GUO | 2009 | Molecular Sciences2009，10，： | 1 |
| 20 | CD90 is identified as a candidate marker for cancer stem cells in primary high-grade gliomas using tissue microarrays显示文摘 | JINTANG HE YASHU LIU THANT ZHU | 2012 | Mol Cell Proteomics2012，11，6： | 1 |
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