|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Expression of apoptosis-related factors in chronic cyclosporine nephrotoxicity after cyclosporine withdrawal显示文摘AIM: To examine whether the reversibility of chronic cyclosporine A (CsA) nephrotoxicity is associated with apoptotic cell death and its regulatory factors. METHODS: Chronic CsA nephrotoxicity was induced in Sprague- Dawley rats by administering CsA (15 mg/kg, sc) for 5 weeks, and then withdrawing it for 5 or 10 weeks. The effect of CsA withdrawal on apoptotic cell death was evaluated by an in situ TdT-mediated deoxyuridine triphos- phate-biotin nick end-labeling (TUNEL) assay and the expression of pro-apoptotic [(transforming growth factor- beta1 (TGF-β1) and Fas] and anti-apoptotic [epidermal growth factors (EGF) and Bcl-2] factors. RESULTS: Discontinuation of CsA induced significant decreases in TUNEL-positive cells in a time-dependent manner and the reduction in TUNEL-positive cells was correlated with the tubulointerstitial fibrosis score (r=0.919, P<0.01). Upregulation of TGF-β1 and Fas expression in CsA-treated rat kidneys was decreased significantly after with- drawal of CsA. In contrast, downregulated EGF and Bcl-2 expression returned to normal or supernormal levels. CONCLUSION: CsA withdrawal is associated with a decrease in apoptotic cell death and with changes in the expression of pro-apoptotic and anti-apoptotic molecules involved in renal wound repair. This may constitute one of the mechanisms underlying the reversibility of chronic CsA nephrotoxicity. | CanLI Sun-wooLIM Bo-kyungSUN Bum-soonCHOI SylviaGLOWACKA AlisonJCOX DarrenJKELLY Yong-sooKIM JinKIM Byung-keeBANG Chul-wooYANG | 2004 | Acta Pharmacologica Sinica2004，25，4： | 16 |
| 2 | 高强钢金属芯焊丝E120C-K4熔敷金属粗晶区显微组织对冲击韧性的影响显示文摘采用焊接热模拟通过改变冷却时间(t8/5),研究了金属芯焊丝E120C-K4多道焊熔敷金属模拟粗晶区(CGHAZ)显微组织对冲击韧性的影响规律.结果表明,当t8/5为6~12 s时,CGHAZ显微组织由蜕化上贝氏体、粒状贝氏体和针状铁素体组成,奥氏体晶粒内部形成复相分割结构,冲击韧性最好.而当t8/5为30~120 s时CGHAZ显微组织主要由粒状贝氏体和针状铁素体组成,冲击韧性下降.t8/5为120 s时,冲击韧性最差,–40℃冲击吸收能量仅为24 J.t8/5为6~12 s时韧性改善的关键是形成复相分割微观结构;晶粒细小;单位距离上大角度晶界数量多. | 苏小虎 栗卓新 李红 JinKim Hee 孟波 | 2019 | 焊接学报2019，40，10： | 5 |
| 3 | Pseudoaneurysm of gastroduodenal artery following radical gastrectomy for gastric carcinoma patients显示文摘We report a rare case of postoperative pseudoaneurysm of the gastroduodenal artery following radical gastrectomy.Surgical trauma to the gastroduodenal artery during regional lymphadenectomy was considered as the cause of the postoperative pseudoaneurysm. The pseudoaneurysm was successfully managed by ligating the bleeding vessel. We should consider the possibility of pseudoaneurysm formation in a patient with gastrointestinal bleeding in the postoperative period following radical gastrectomy with regional lymph node and perivascular lymphatic dissection. | Dong YiKim Jae KyoonJoo SeongYeobRyu Young JinKim Shin KonKim Yong-Yeon Jung | 2003 | World Journal of Gastroenterology2003，9，12： | 4 |
| 4 | Frequency and risk factors of renal impairment during long‐term adefovir dipivoxil treatment in chronic hepatitis B patients显示文摘 | Yu JinKim Hyun ChinCho Dong HyunSinn Geum‐YounGwak Moon SeokChoi Kwang CheolKoh Seung WoonPaik Byung ChulYoo Joon HyeokLee | 2012 | Journal of Gastroenterology and Hepatology2012，，2： | 2 |
| 5 | Hepatitis B virus X protein sensitizes UV‐induced apoptosis by transcriptional transactivation of Fas ligand gene expression显示文摘 | Sang YongKim Jeong KiKim Hye JinKim Jeong KeunAhn | 2008 | IUBMB Life2008，，9： | 2 |
| 6 | Contrasting activity of Hedgehog and Wnt pathways according to gastric cancer cell differentiation: Relevance of crosstalk mechanisms显示文摘 | Jie‐HyunKim Hyun SooShin Sang HunLee InohkLee Yeo SongLee Jun ChulPark Yu JinKim Jae BockChung Yong ChanLee | 2010 | Cancer Science2010，，2： | 1 |
| 7 | Recovery of remanent polarization of poly(vinylidene fluoride co trifluoroethylene ) thin film after high temperature annealing sign topographically nanpstructured aluminuum bottom electrode 显示文摘 | Jungpark Y Jukang S Park C Woo E Skin K Jinkim K | 2007 | Applied Physics Letters2007，90，22： | 1 |
| 8 | Recovery of remanent polarization of poly(vinylidene fluoride-co-trifluoroethylene) thin film after high temperature annealing sign topographically nanpstructured aluminuum bottom electrode 显示文摘 | Youn Jungpark Seok Jukang Cheomin Park Euntaek Woo Kynsoon Skin Kap Jinkim | 2007 | Applied Physics Letters2007，90，20： | 1 |
| 9 | 18F‐FDG uptake and its clinical relevance in primary gastric lymphoma显示文摘 | Jun HoYi Seok JinKim Joon YoungChoi Young HyehKo Byung‐TaeKim Won SeogKim | 2010 | Hematol. Oncol2010，，2： | 1 |
| 10 | Increased toll‐like receptor 9 expression in cervical neoplasia显示文摘 | Jeong‐WonLee Jung‐JooChoi Eun SungSeo Mi JinKim Woo YoungKim Chel HunChoi Tae‐JoongKim Byoung‐GieKim Sang YongSong Duk‐SooBae | 2007 | Mol Carcinog2007，，11： | 1 |
| 11 | Kain at retreatment alers TGF-133 gene expression in the rat hippocampus 显示文摘 | H young Chun Kima Guoying Bing b Seong JinKim c | 2002 | Molecular Brain Research2002，108，1： | 1 |
| 12 | Critical role for matrix metalloproteinase‐9 in platelet‐activating factor‐induced experimental tumor metastasis显示文摘 | Hyun‐MiKo Jee‐HaeKang BongnamJung Han‐AKim Sung JunPark Kyoung‐JinKim Yeong‐RimKang Hern‐KuLee Suhn‐YoungIm | 2007 | Int J Cancer2007，，6： | 1 |
| 13 | Proteomic profiling and identification of cofilin responding to oxidative stress in vascular smooth muscle显示文摘 | Chang‐KwonLee Hyo‐JunPark Hyeon HaSo Hyo JinKim Keun SangLee Wahn SooChoi Hwan MyungLee Kyung‐JongWon Taek JoonYoon Tae‐KyuPark BokyungKim | 2006 | Proteomics2006，，24： | 1 |
| 14 | Quantification of superparamagnetic iron oxide‐mediated signal intensity change in patients with liver cirrhosis using T2 and T2* mapping: A preliminary report显示文摘 | Yong EunChung Mi‐SukPark Myoung SooKim EunjuKim JaeseokPark Ho‐TaekSong Jin YoungChoi Myeong‐JinKim Ki WhangKim | 2010 | J Magn Reson Imaging2010，，6： | 1 |
| 15 | Is International Prognostic Scoring System (IPSS) still standard in predicting prognosis in patients with myelodysplastic syndrome? External validation of the WHO Classification‐Based Prognostic Scoring System (WPSS) and comparison with IPSS显示文摘 | Min JaePark Hee‐JinKim Sun‐HeeKim Dong HwanKim Seok JinKim Jun HoJang KihyunKim Won SeogKim Chul WonJung | 2008 | European Journal of Haematology2008，，： | 1 |
| 16 | Light‐Regulated Release of DNA and Its Delivery to Nuclei by Means of Photolabile Gold Nanoparticles显示文摘 | GangHan Chang‐ChengYou Byoung‐jinKim Rosemary S.Turingan Neil S.Forbes Craig T.Martin Vincent M.Rotello | 2006 | Angewandte Chemie International Edition2006，，19： | 1 |
| 17 | Separation of nitrogen heteroeyclic compounds from model coal tar fraction by solvent extraction显示文摘 | Su Jinkim Yong Jinchun | | 0，，10： | 1 |
| 18 | Persistent Regional Diastolic Dysfunction after Myocardial Ischemia and the Effect of Statin Treatment: Assessment with Two‐Dimensional Radial Strain Rate显示文摘 | Hyung‐KwanKim Sung‐AChang Dae‐WonSohn Dae‐HeeKim Yong‐JinKim Byung‐HeeOh Young‐BaePark | 2010 | Echocardiography2010，，3： | 1 |
| 19 | Anti‐fibrotic effect of chorionic plate‐derived mesenchymal stem cells isolated from human placenta in a rat model of CCl显示文摘 | Min‐JaeLee JieunJung Kyu‐HwanNa Ji SukMoon Hey‐JinLee Jae‐HwanKim Gwang IlKim Sung‐WonKwon Seong‐GyuHwang Gi JinKim | 2010 | J Cell Biochem2010，，6： | 1 |
| 20 | Retrograde cerebral perfusion during hypothermic circulatory arrest reduces neurologic morbidity显示文摘 | Jinkims E Bolling SF | 1995 | J Thorac Cardiovasc Surg1995，109，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员