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| 1 | Kaempferol protects ethanol-induced gastric ulcers in mice via pro-inflammatory cytokines and NO显示文摘胃的溃疡(GU ) 是在全世界影响许多人的普通病理。过多的白酒消费是 GU 的主要原因之一;然而,仍然有为 GU 的预防或治疗的有效的药的缺乏。在这研究,我们在老鼠把保护的效果和 kaempferol (KAE ) 的可能的机制与尖锐导致乙醇的损害作比较到胃的 mucosa。Fasted 老鼠口头上地被给车辆(0.9% 盐) , omeprazole (20 mg/kg ) ,或为在在由有绝对乙醇(10 ml/kg ) 的挑战的 GU 模型的建立以前的不同试验性的集合的 1 h 的 KAE (40, 80,或 160 mg/kg ) 。动物是 euthanized 在乙醇吸入以后的 1 h,和他们的血浆和胃纸巾服从于进一步的检查。宏观、显微镜的损害,和免疫学的和生物化学的参数被观察。发炎的效果用下列指示物被调查:肿瘤坏死因素 --(TNF-) , interleukin-1 (IL-1 ) , IL-6, myeloperoxidase (军邮局) ,和氮的氧化物(没有) 。结果证明 KAE 显著地减少了溃疡索引,增加了预防索引,完全保护了 mucosa 免受损害,和保存胃的 mucosal glycoprotein 的伤害。KAE 减少了军邮局活动和支持 inflammatory cytokine (TNF- ,和 IL-1 ) 铺平,并且没改进层次。KAE 的 gastroprotective 活动可能被归因于胃的有粘液的 glycoproteins 层次的保藏,这样由禁止嗜中性的累积和军邮局活动,调整支持 inflammatory cytokines 的层次,并且不改进生产。 | Qinchen Li Xinxin Hu Yanhan Xuan Jianghua Ying Yujia Fei Jielu Rong Yong Zhang Jian Zhang Chunyan Liu Zheng Liu | 2018 | Acta Biochimica et Biophysica Sinica2018，50，3： | 18 |
| 2 | MicroRNA-21 in the pathogenesis of acute kidney injury显示文摘Acute kidney injury(AKI),associated with significant mor-bidity and mortality,is widely known to involve epithelial apoptosis,excessive inflammation,and fibrosis in re-sponse to ischemia or reperfusion injury,which results in either chronic pathological changes or death.Therefore,it is imperative that investigations are conducted in order to fi nd effective,early diagnoses,and therapeutic targets needed to help prevent and treat AKI.However,the mech-anisms modulating the pathogenesis of AKI still remain largely undetermined.MicroRNAs(miRNAs),small non-coding RNA molecules,play an important role in several fundamental biological and pathological processes by a post transcriptional regulatory function of gene expres-sion.MicroRNA-21(miR-21)is a recently identifi ed,typi-cal miRNA that is functional as a regulator known to be involved in apoptosis as well as inflammatory and fi brotic signaling pathways in AKI.As a result,miR-21 is now considered a novel biomarker when diagnosing and treat-ing AKI.This article reviews the correlative literature and research progress regarding the roles of miR-21 in AKI. | Ya-Feng Li Ying Jing Jielu Hao Nathan C Frankfort Xiaoshuang Zhou Bing Shen Xinyan Liu Lihua Wang Rongshan Li | 2013 | Protein & Cell2013，4，11： | 18 |
| 3 | Response of the sensorimotor cortex of cerebral palsy rats receiving transplantation of vascular endothelial growth factor 165-transfected neural stem cells显示文摘Neural stem cells are characterized by the ability to differentiate and stably express exogenous genes. Vascular endothelial growth factor plays a role in protecting local blood vessels and neurons of newborn rats with hypoxic-ischemic encephalopathy. Transplantation of vascular endothelial growth factor-transfected neural stem cells may be neuroprotective in rats with cerebral palsy. In this study, 7-day-old Sprague-Dawley rats were divided into five groups:(1) sham operation(control),(2) cerebral palsy model alone or with(3) phosphate-buffered saline,(4) vascular endothelial growth factor 165 + neural stem cells, or(5) neural stem cells alone. The cerebral palsy model was established by ligating the left common carotid artery followed by exposure to hypoxia. Phosphate-buffered saline, vascular endothelial growth factor + neural stem cells, and neural stem cells alone were administered into the sensorimotor cortex using the stereotaxic instrument and microsyringe. After transplantation, the radial-arm water maze test and holding test were performed. Immunohistochemistry for vascular endothelial growth factor and histology using hematoxylin-eosin were performed on cerebral cortex. Results revealed that the number of vascular endothelial growth factor-positive cells in cerebral palsy rats transplanted with vascular endothelial growth factor-transfected neural stem cells was increased, the time for finding water and the finding repetitions were reduced, the holding time was prolonged, and the degree of cell degeneration or necrosis was reduced. These findings indicate that the transplantation of vascular endothelial growth factor-transfected neural stem cells alleviates brain damage and cognitive deficits, and is neuroprotective in neonatal rats with hypoxia ischemic-mediated cerebral palsy. | Jielu Tan Xiangrong Zheng Shanshan Zhang Yujia Yang Xia Wang Xiaohe Yu Le Zhong | 2014 | Neural Regeneration Research2014，9，19： | 4 |
| 4 | Entropy,Periodicity,and Graphs with Zero Euler Characteristic显示文摘Let G be a graph which contains exactly one simple closed curve. We prove that a continuous map f : G → G has zero topological entropy if and only if there exist at most k ≤ |(Edg(G)+ End(G)+3)/2] different odd numbers n1,...,nk such that Per(f) is contained in ∪i=1^k ∪j=0^∞ ni2^j, where Edg(G) is the number of edges of G and End(G) is the number of end points of G. | JieLU JinChengXIONG JianCHEN | 2004 | Acta Mathematica Sinica,English Series2004，20，3： | 3 |
| 5 | Bromophenols coupled with derivatives of amino acids and nucleosides from the red alga Rhodomela confervoides显示文摘 | Zhao Jielu Ma Ming Wang Sujuan | 2005 | J Nat Prod2005，68，： | 1 |
| 6 | Bromophenols coupled with methyl 9-Ureidobutyrate and bromophenol sulfates from the red alga Rhodomela confervoides显示文摘 | Ma Ming Zhao Jielu Wang Sujuan | 2006 | J Nat Prod2006，69，： | 1 |
| 7 | Bromophenols coupled with nucleoside bases and brominated tetrahydroisoquinolines from the red alga Rhodomela confervoides显示文摘 | Ma Ming Zhao Jielu Wang Sujuan | 2007 | J Nat Prod2007，70，： | 1 |
| 8 | The efficacy and safety of tradi-tional chinese medicine (jiang zhi granule) for nonalcoholic Fatty liv-er: a multicenter, randomized, placebo-controlled study 显示文摘 | Jielu Pan Miao Wang Guang Ji | 2013 | EvidBased Complement Altemat Med2013，，96： | 1 |
| 9 | Lentiviral-mediated vascular endothelial growth factor 165 gene transfer into neural stem cells promotes proliferation显示文摘We constructed a lentiviral vector carrying vascular endothelial growth factor 165, which was used to transfect neural stem cells. The transfection rate was approximately 50%, as determined by flow cytometry. Vascular endothelial growth factor protein was detected in neural stem cells and pro-moted proliferation. | Shanshan Zhang Xiangrong Zheng Fei Yin Jielu Tan Yujia Yang | 2011 | Neural Regeneration Research2011，6，19： | 1 |
| 10 | Heat‐shock protein 27: A potential biomarker for hepatocellular carcinoma identified by serum proteome analysis显示文摘 | Ju‐TaoFeng Yin‐KunLiu Hai‐YanSong ZhiDai Lun‐XiuQin Mohamad RadwanAlmofti Cai‐YunFang Hao‐JieLu Peng‐YuanYang Zhao‐YouTang | 2005 | Proteomics2005，，17： | 1 |
| 11 | Bromophenol derivatives from the red alga Rhodomela confervoides显示文摘 | Zhao Jielu Fan Xiao Wang Sujuan | 2004 | J Nat Prod2004，67，： | 1 |
| 12 | Design and synthesis of simpliifed taxol analogs based on the T-Taxol bioactive conformation显示文摘 | Zhao Jielu Bane Susan Snyder James P.Hu Haipeng Mukherjee K amalika Slebodnick Carla Kingston David G.I | | 0，，24： | 1 |
| 13 | Removal of Ni(II) from Aqueous Solutions by Nanoscale Magnetite显示文摘 | Xue SongWang Jun JunRen Hai JieLu LeiZhu FeiLiu Qian QianZhang JuanXie | 2010 | Clean Soil Air Water2010，，12： | 1 |
| 14 | Heat‐shock protein 27: A potential biomarker for hepatocellular carcinoma identified by serum proteome analysis显示文摘 | Ju‐TaoFeng Yin‐KunLiu Hai‐YanSong ZhiDai Lun‐XiuQin Mohamad RadwanAlmofti Cai‐YunFang Hao‐JieLu Peng‐YuanYang Zhao‐YouTang | 2005 | Proteomics2005，，17： | 1 |
| 15 | HYDROLYSIS OF PAPER-DISHWARE WASTES BY CELLULASE显示文摘The optimum conditions of hydrolysis of cellulosic wastes by cellulase were studied. The results show that the optimum conditions of sulfuric acid pretreatment were sulfuric acid consistency 0.3M,pretreatment temperature 100℃, pretreatment time 4hours. After sulfuric acid pretreatment, the optimum conditions of hydrolysis by cellulase were enzymatic temperature 50℃,enzymatic time 48hours,pH4.8,the charge of cellulase 100IU/g and the substraste consistency 60g/l. Meanwhile this paper studies that the structural change of cellulose during sulfuric acid pretreatment and cellulase hydrolysis by analyzing the infrared spectra. | JieLu ShulanShi RunanYang FuzhengLiang | 2004 | 天津科技大学学报2004，19，A02： | 0 |
| 16 | WHITMAN IN CHINA显示文摘More than ninety years have elapsed since Walt Whitman, the celebratedAmerican poet, breathed his last. His poetry, however, is still sung far and widewith vitality and power. His rise to popularity has been so rapid that Leaves ofGrass has heen printed in almost all the world’s major languages. The great voiceof the New World is now speaking for people all over the world. In that sense,Whitman’s brilliant poetry has become part not only of the rare heritage ofAmerican literature but also of the rare heritage of world literature. | Zhao Jielu | 1986 | 西南大学学报(社会科学版)1986，18，S1： | 0 |
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