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| 1 | Ideal cardiovascular health and incidence of atherosclerotic cardiovascular disease among Chinese adults:the China-PAR project显示文摘Existing evidence on the relationship between cardiovascular health(CVH) metrics and cardiovascular disease(CVD) was primarily derived from western populations. We aimed to evaluate the benefits of ideal CVH metrics on preventing incident atherosclerotic CVD(ASCVD) in Chinese population. This study was conducted among 93,987 adults from the China-PAR project(Prediction for ASCVD Risk in China) who were followed up until 2015. Cox proportional hazard regression models were used to estimate the hazard ratios(HRs) and their corresponding 95% confidence intervals(CIs) of CVH metrics for the risk of ASCVD, including coronary heart disease(CHD), stroke and ASCVD death. We further estimated the population-attributable risk percentage(PAR%) of these metrics in relation to each outcome. We observed gradient inverse associations between the number of ideal CVH metrics and ASCVD incidence. Compared with participants having ≤2 ideal CVH metrics, the multivariable-adjusted HRs(95% CIs) of ASCVD for those with 3, 4, 5, 6 and 7 ideal CVH metrics were 0.83(0.74–0.93), 0.66(0.59–0.74), 0.55(0.48–0.61), 0.44(0.38–0.50) and 0.24(0.18–0.31), respectively(P for trend <0.0001). Approximately 62.1% of total ASCVD, 38.7% of CHD, 66.4% of stroke, and 60.5% of ASCVD death were attributable to not achieving all the seven ideal CVH metrics. After adjusting effects of ideal health factors, having four ideal health behaviors could independently bring adults health benefits in preventing 17.4% of ASCVD, 18.0% of CHD, 16.7% of stroke, and 10.1% of ASCVD death. Among all the seven CVH metrics, to keep with ideal blood pressure(BP) implied the largest public health gains against various ASCVD events(PAR% between 33.0% and 47.2%), while ideal diet was the metric most difficult to be achieved in the long term. Our study indicates that the more ideal CVH metrics adults have, the less ASCVD burden there is in China. Special efforts of health education and behavior modification should be made on keeping ideal BP and dietary habits in general Chinese population to prevent the epidemic of ASCVD. | Chao Han Fangchao Liu Xueli Yang Jichun Chen Jianxin Li Jie Cao Ying Li Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Dongshen Hu Xiangfeng Lu Xigui Wu Dongfeng Gu | 2018 | Science China(Life Sciences)2018，61，5： | 60 |
| 2 | Mapping QTLs with epistatic effects and QTL×environment interactions for plant height using a doubled haploid population in cultivated wheat显示文摘Quantitative trait loci (QTLs) for plant height in wheat (Triticum aestivum L.) were studied using a set of 168 doubled haploid (DH) lines, which were derived from the cross Huapei 3/Yumai 57. A genetic linkage map was constructed using 283 SSR and 22 EST-SSR markers. The DH population and the parents were evaluated for wheat plant height in 2005 and 2006 in Tai’an and 2006 in Suzhou. QTL analyses were performed using the software of QTLNetwork version 2.0 based on the mixed linear model. Four additive QTLs and five pairs of epistatic effects were detected, which were distributed on chromosomes 3A, 4B, 4D, 5A, 6A, 7B, and 7D. Among them, three additive QTLs and three pairs of epistatic QTLs showed QTL×environment interactions (QEs). Two major QTLs, Qph4B and Qph4D, which accounted for 14.51% and 20.22% of the phenotypic variation, were located similar to the reported locations of the dwarfing genes Rht1 and Rht2, respectively. The Qph3A-2 with additive effect was not reported in previous linkage mapping studies. The total QTL effects detected for the plant height explained 85.04% of the phenotypic variation, with additive effects 46.07%, epistatic effects 19.89%, and QEs 19.09%. The results showed that both additive effects and epistatic effects were important genetic bases of wheat plant height, which were subjected to environmental modifications, and caused dramatic changes in phenotypic effects. The information obtained in this study will be useful for manipulating the QTLs for wheat plant height by molecular marker-assisted selection (MAS). | Kunpu Zhang Jichun Tian Liang Zhao Shanshan Wang | 2008 | Journal of Genetics and Genomics2008，35，2： | 36 |
| 3 | Predicting lifetime risk for developing atherosclerotic cardiovascular disease in Chinese population:the China-PAR project显示文摘Evidence on the lifetime risk for atherosclerotic cardiovascular disease(ASCVD) is insufficient;yet,estimating an individual's lifetime risk allows for a comprehensive assessment of ASCVD burden.We developed and validated lifetime risk prediction equations for ASCVD using four large and ongoing prospective cohorts of Chinese,the China-PAR project(Prediction for ASCVD Risk in China).Sexspecific equations were developed using two cohorts(as the derivation cohort) of 21,320 participants.Two other independent cohorts with 14,123 and 70,838 participants were used for their external validation,respectively.We evaluated both calibration and discrimination measures for model performance.Furthermore,we estimated ASCVD-free years lost or excess absolute risk attributable to high 10-year risk(!10.0%) and/or high lifetime risk(!32.8%).After 12.3 years' follow-up of the derivation cohort,1048 ASCVD events and 1304 non-ASCVD deaths were identified.Our sex-specific equations had good internal validation,with discriminant C statistics of 0.776(95% confidence interval [CI]:0.757–0.794) and 0.801(95% CI:0.778–0.825),and calibration χ~2 of 9.2(P = 0.418) and 5.6(P = 0.777) for men and women,respectively.Good external validation was also demonstrated with predicted rates closely matched to the observed ones.Compared with men having both low 10-year and low lifetime risk,men would develop ASCVD 3.0,4.6 and 8.6 years earlier if they had high 10-year risk alone,high lifetime risk alone,or both high 10-year and high lifetime risk at the index age of 35 years,respectively.We developed wellperformed lifetime risk prediction equations that will help to identify those with the greatest potential to avert ASCVD burden after implementation of innovative clinical and public health interventions in China. | Fangchao Liu Jianxin Li Jichun Chen Dongsheng Hu Ying Li Jianfeng Huang Xiaoqing Liu Xueli Yang Jie Cao Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Xigui Wu Dongfeng Gu Xiangfeng Lu | 2018 | Science Bulletin2018，63，12： | 30 |
| 4 | Review of the uncertainty analysis of groundwater numerical simulation显示文摘Groundwater system is a complex and open system, which is affected by natural conditions and human activities. Natural hydrological processes is conceptualized through relatively simple flow governing equations in groundwater models. Moreover, observation data is always limited in field hydrogeological conditions. Therefore, the predictive results of groundwater simulation often deviate from true values, which is attribute to the uncertainty of groundwater numerical simulation. According to the process of system simulation, the uncertainty sources of groundwater numerical simulation can be divided into model parameters, conceptual model and observation data uncertainties. In addition, the uncertainty stemmed from boundary conditions is sometimes refered as scenario uncertainty. In this paper, the origination and category of groundwater modeling uncertainty are analyzed. The recent progresses on the methods of groundwater modeling uncertainty analysis are reivewed. Furthermore, the researches on the comprehensive analysis of uncertainty sources, and the predictive uncertainty of model outputs are discussed. Finally, several prospects on the deveolpment of groundwater modeling uncetainty analysis are proposed. | WU JiChun ZENG XianKui | 2013 | Chinese Science Bulletin2013，58，25： | 24 |
| 5 | Spatiotemporal variability of permafrost degradation on the Qinghai-Tibet Plateau显示文摘Based on data from six meteorological stations in the permafrost regions, 60 boreholes for long-term monitoring of permafrost temperatures, and 710 hand-dug pits and shallow boreholes on the Qinghai-Tibet Plateau (QTP), the spatiotemporal variability of permafrost degradation was closely examined in relation to the rates of changes in air, surface, and ground temperatures. The de-cadal averages and increases in the mean annual air temperatures (MAATs) from 1961-2010 were the largest and most persistent during the last century. MAATs rose by 1.3℃, with an average increase rate of 0.03℃/yr. The average of mean annual ground surface temperatures (MAGSTs) increased by 1.3℃ at an average rate of 0.03℃/yr. The rates of changes in ground temperatures were -0.01 to 0.07℃/yr. The rates of changes in the depths of the permafrost table were -1 to +10 cm/yr. The areal extent of permafrost on the QTP shrank from about 1.50×106 km2 in 1975 to about 1.26×106 km2 in 2006. About 60% of the shrinkage in area of permafrost occurred during the period from 1996 to 2006. Due to increasing air temperature since the late 1980s, warm (>-1℃) permafrost has started to degrade, and the degradation has gradually expanded to the zones of transitory (-1 to -2℃) and cold (<-2℃) permafrost. Permafrost on the southern and southeastern plateau degrades more markedly. It is projected that the degradation of permafrost is likely to accelerate, and substantial changes in the distributive features and thermal regimes of permafrost should be anticipated. However, regarding the relationships between degrading permafrost and the degradation of rangelands, it is still too early to draw reliable conclusions due to inadequate scientific criteria and evidence. | HuiJun Jin DongLiang Luo ShaoLing Wang LanZhi Lv JiChun Wu | 2011 | Research in Cold and Arid Regions2011，3，4： | 16 |
| 6 | Processes and modes of permafrost degradation on the Qinghai-Tibet Plateau显示文摘Climate warming must lead the mainly air temperature controlled permafrost to degrade.Based on the numerical simulation,the process of permafrost degradation can be divided into five stages,i.e.,starting stage,temperature rising stage,zero geothermal gradient stage,talic layers stage,and disappearing stage,according to the shape of ground temperature profile.Permafrost on the Qinghai-Tibet Plateau (QTP) is generally considered a relic from late Pleistocene,and has been degenerating as a whole during Holocene.According to spatial-temporal compensation,the present thermal state discrepancy of permafrost in different areas on the QTP may correspond with their degradation stages.On the QTP,permafrost in the high and middle mountains belongs to temperature rising stage,the permafrost thermal state is transiting from late rising temperature stage to zero geothermal gradient stage that is distributed in the middle-low-mountains.Permafrost that is in a zero gradient stage mainly appears in the high plateau and valley,whereas the transition from zero gradient stage to talic layers stage of permafrost is located in the vicinity of the lower limit of permafrost,and permafrost is disappearing from margin of perennially frozen ground.There are two modes of perennially frozen ground thawing,thawing from top to bottom and thawing from bottom to top respectively.During the temperature rising stage,when the heat flux in the perennially frozen soil layer is less than that in the unfrozen soil underlying frozen soil layer,the geothermal flux is partly used to thaw the base of permafrost,and permafrost thaws from bottom to top.With the decrease of thermal gradient in the perennially frozen ground,the heat that is used to thaw permafrost base increases,and geothermal heat will be entirely consumed to thaw the base of permafrost until the temperature gradient reaches zero thermal gradient state.On the other hand,the disappearance of permafrost may be delayed by 'thermal offset' and 'seasonal offset' effects in the upper of permafrost layer.When ground surface temperature rises to the level that can counteract the thermal offset effect,heat accumulation in the active layer would start,and the thickness of the active layer increases until a talic layer to appear.This process can be intensified by the 'seasonal anti-offset effect'. | WU JiChun,SHENG Yu,WU QingBai & WEN Zhi State Key Laboratory of Frozen Soil Engineering,Cold and Arid Regions Environmental and Engineering Research Institute,Chinese Academy of Sciences,Lanzhou 730000,China | 2010 | Science China Earth Sciences2010，53，1： | 16 |
| 7 | The crosstalk between autophagy and ferroptosis:what can we learn to target drug resistance in cancer?显示文摘Autophagy is a conserved intracellular degradation system that plays a dual role in cell death;thus,therapies targeting autophagy in cancer are somewhat controversial.Ferroptosis is a new form of regulated cell death featured with the iron-dependent accumulation of lethal lipid ROS.This pathway is morphologically,biochemically and genetically distinct from other forms of cell death.Accumulating studies have revealed crosstalk between autophagy and ferroptosis at the molecular level.In this review,we summarize the mechanisms of ferroptosis and autophagy,and more importantly,their roles in the drug resistance of cancer.Numerous connections between ferroptosis and autophagy have been revealed,and a strong causal relationship exists wherein one process controls the other and can be utilized as potential therapeutic targets for cancer.The elucidation of when and how to modulate their crosstalk using therapeutic strategies depends on an understanding of the fine-tuned switch between ferroptosis and autophagy,and approaches designed to manipulate the intensity of autophagy might be the key. | Yulu Zhou Yong Shen Cong Chen Xinbing Sui Jingjing Yang Linbo Wang Jichun Zhou | 2019 | Cancer Biology & Medicine2019，16，4： | 9 |
| 8 | Cancer-associated fibroblasts in breast cancer:Challenges and opportunities显示文摘The tumor microenvironment is proposed to contribute substantially to the progression of cancers,including breast cancer.Cancer-associated fibroblasts(CAFs)are the most abundant components of the tumor microenvironment.Studies have revealed that CAFs in breast cancer originate from several types of cells and promote breast cancer malignancy by secreting factors,generating exosomes,releasing nutrients,reshaping the extracellular matrix,and suppressing the function of immune cells.CAFs are also becoming therapeutic targets for breast cancer due to their specific distribution in tumors and their unique biomarkers.Agents interrupting the effect of CAFs on surrounding cells have been developed and applied in clinical trials.Here,we reviewed studies examining the heterogeneity of CAFs in breast cancer and expression patterns of CAF markers in different subtypes of breast cancer.We hope that summarizing CAFrelated studies from a historical perspective will help to accelerate the development of CAF-targeted therapeutic strategies for breast cancer. | Dengdi Hu Zhaoqing Li Bin Zheng Xixi Lin Yuehong Pan Peirong Gong Wenying Zhuo Yujie Hu Cong Chen Lini Chen Jichun Zhou Linbo Wang | 2022 | Cancer Communications2022，42，5： | 9 |
| 9 | Study of the minerogenetic mechanism and origin of Qinghai nephrite from Golmud, Qinghai, Northwest China显示文摘Electronic microprobe analysis showed that all QN samples are mainly composed of tremolite and minor accessory minerals, such as diopside, calcite, serpentinite, and magnetite. According to the cation coefficients, the crystallo-chemistrygenesis illustration demonstrates that all QN deposits are contact metasomatic. Depending on the mole percent of Fe^(2+(3+))/(Mg^(2+)+Fe^(2+(3+)) and the content of Cr, Co, and Ni in all QN samples measured by X-ray fluorescence spectroscopy(XRF) and inductively coupled plasma-mass spectrometry(ICP-MS), green and azure-green QNs are characterized as serpentinite-related contact metasomatic deposit(S-type), whereas white, green-white, brown, blue-violet, yellow, and viridis QNs are dolomite-related contact metasomatic deposit(D-type). The assemblages and chemical composition of accessory minerals of the eight-color QN samples show evident characteristics, which reveal four possible ore-forming processes. We also measured trace and rare earth elements(REEs) in these samples through ICP-MS to deduce the origin of and the changes in metallogenic conditions. The chondrite-normalized REE patterns of D-type QN exhibit moderately negative Eu anomalies with moderate light REE enrichment, flat heavy REE(HREE), and low(50)REE concentrations, similar to dolomitic marble. Green QN samples of S-type show enrichment in HREE and moderately negative Eu anomalies, which is consistent with characteristics of dunite. Whereas azure-green QN samples of S-type exhibit a right-dipping V-type curve with severe depletion in Eu(δEu=0.36–0.47), in accordance with the characteristics of gabbro from Yushigou ophiolite in North Qilian mountains. Furthermore, this finding is consistent with the content of trace elements and the petrographic analysis results. On the basis of several significant differences in the characteristic elements, which may have been affected by the metallogenic environment, we inferred the differences in oxygen fugacity and basicity of mineralization environments in different-colored QNs. | YU HaiYan WANG RuCheng GUO JiChun LI JiaGui YANG XiaoWen | 2016 | Science China Earth Sciences2016，59，8： | 8 |
| 10 | Fruit and vegetable consumption,cardiovascular disease,and all-cause mortality in China显示文摘Evidence about the response patterns of fruit and vegetable consumption with the risk of cardiovascular disease(CVD)and allcause mortality was inconsistent.These associations were examined using a large-scale,population-based Chinese cohort comprising 100,728 participants.A food-frequency questionnaire was used to assess fruit and vegetable consumption.Outcomes were ascertained by interviewing individuals or their proxies and checking hospital records or death certificates.Cox proportional hazards regression was used to calculate hazard ratios(HRs)with 95% confidence intervals(CIs).At the 736,668 person-years of follow-up,3,677 CVD cases and 5,466 deaths were identified.The multivariable-adjusted HRs for CVD across increasing quartiles of total fruit and vegetable consumption were 1(reference),0.94(95%CI=0.85-1.04),0.89(95%CI=0.80-0.98),and 0.85(95%CI=0.77-0.95).Moreover,participants in the highest quartile displayed a 13% lower risk of all-cause mortality(HR=0.87;95%CI=0.80-0.95).A nonlinear dose-response relation was found for CVD,without additional benefits beyond a consumption of600 g d-1,whereas the all-cause mortality risk decreased along with higher consumption,with a linear trend.These associations remained significant for fruit consumption but not for vegetable consumption.Our findings indicated that greater fruit and vegetable consumption was significantly associated with a lower risk of CVD and all-cause mortality.Increasing fruit and vegetable consumption,especially fruit,in the general population would prevent CVD and premature mortality. | Jun Wang Fangchao Liu Jianxin Li Keyong Huang Xueli Yang Jichun Chen Xiaoqing Liu Jie Cao Shufeng Chen Chong Shen Ling Yu Fanghong Lu Xianping Wu Liancheng Zhao Ying Li Dongsheng Hu Jianfeng Huang Dongfeng Gu Xiangfeng Lu | 2022 | Science China(Life Sciences)2022，65，1： | 8 |
| 11 | Associations of egg consumption with incident cardiovascular disease and all-cause mortality显示文摘Eggs are nutrient-dense while also loaded with abundant cholesterol, thus making the public hesitant about their consumption.We conducted the study to investigate if egg consumption is associated with incident cardiovascular disease(CVD) and all-cause mortality. Using the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China, we included 102,136 adults free of CVD and assessed their egg consumption with food-frequency questionnaires. CVD endpoints and all-cause mortality were confirmed during follow-ups by interviewing participants or their proxies and checking hospital records/death certificates.The HRs(95% CIs) were calculated using the cohort-stratified Cox regression models. During 777,163 person-years of followup, we identified 4,848 incident CVD and 5,511 deaths. U-shaped associations of egg consumption with incident CVD and allcause mortality were observed. Compared with consumption of 3–<6/week, the multivariable-adjusted HRs(95% CIs) of <1/week and ≥10/week for incident CVD were 1.22(1.11 to 1.35) and 1.39(1.28 to 1.52), respectively. The corresponding HRs(95% CIs) for all-cause mortality were 1.29(1.18 to 1.41) and 1.13(1.04 to 1.24). Our findings identified that both low and high consumption were associated with increased risk of incident CVD and all-cause mortality, highlighting that moderate egg consumption of 3–<6/week should be recommended for CVD prevention in China. | Xue Xia Fangchao Liu Xueli Yang Jianxin Li Jichun Chen Xiaoqing Liu Jie Cao Chong Shen Ling Yu Yingxin Zhao Xianping Wu Liancheng Zhao Ying Li Jianfeng Huang Xiangfeng Lu Dongfeng Gu | 2020 | Science China(Life Sciences)2020，63，9： | 7 |
| 12 | Identification and characterization of rice blast resistance gene Pid4 by a combination of transcriptomic profiling and genome analysis显示文摘Map-based cloning of plant disease resistance (R) genes is time-consuming. Here, we reported the isolation of blast R gene Pid4 using comparative transcriptomic profiling and genome-wide sequence analysis. Pid4 encodes a coiled-coil nucleotide-binding site leucine-rich repeat(CC-NBS-LRR) protein and is constitutively expressed at diverse developmental stages in the rice variety Digu. The Pid4 protein is localized in both the nucleus and cytoplasm. Introduction of Pid4 into susceptible rice cultivars confers race-specific resistance to leaf and neck blast. Amino acid sequence comparison and blast resistance spectrum tests showed that Pid4 is a novel R gene, different from the previously reported R genes located in the same gene cluster. A Pid4 Indel marker was developed to facilitate the identification of Pid4 in different rice varieties. We demonstrated that a plant R gene can be quickly isolated using transcriptomic profiling coupled with genome-wide sequence analysis. | Zhixiong Chen Wen Zhao Xiaobo Zhu Chengdong Zou Junjie Yin Mawsheng Chern Xiaogang Zhou Heng Ying Xin Jiang Yongzhen Li Haicheng Liao Mengping Cheng Weitao Li Min He Jing Wang Jichun Wang Bingtian Ma Jirui Wang Shigui Li Lihuang Zhu Xuewei Chen | 2018 | Journal of Genetics and Genomics2018，45，12： | 7 |
| 13 | Simulation of regional land subsidence in the southern Yangtze Delta显示文摘Investigation of the deformation characteristics of individual hydrostratigraphic units is the key to construct a regional land subsidence model. All of 12 hydrostratigraphic units in the study area were discussed throughout. On the basis of the measured data of groundwater level, five kinds of changing patterns of groundwater level were deduced and the relationship between the deformation characteris-tics of aquifer units and the corresponding changing patterns of groundwater level was discussed. The study area is 1.7×104 km2, where the geological condition is complex. The changing patterns of groundwater level the hydrostratigraphic units have experienced vary from site to site and from time to time. Consequently, the deformation characteristics of units are sophisticated. An identical hydros-tratigraphic unit may exhibit different deformation characteristics, such as elasticity, elasto-plasticity, visco-elasticity, and visco-elasto-plasticity, at different sites or during different periods, not to mention the different units. The existing models are difficult to describe the complex visco-elasto-plastic con-stitutive law under the condition of land subsidence. So the Merchant’s model was modified to depict the visco-elasto-plastic behavior of units. Then a three-dimensional flow model with variable parame-ters and a vertical one-dimensional subsidence model were constructed and coupled. The coupled model was applied in simulating land subsidence in the southern Yangtze Delta and a satisfactory re-sult was obtained. The simulation results show that the new coupled model can depict the complex geological conditions and describe the developing process of land subsidence very well in the south-ern Yangtze Delta. The new model can surely be used to predict land subsidence in the future, which is very helpful to taking measurements to control land subsidence. | XUE YuQun WU JiChun ZHANG Yun YE ShuJun SHI XiaoQing WEI ZiXin LI QinFen YU Jun | 2008 | Science China Earth Sciences2008，51，6： | 6 |
| 14 | Experimental and DFT study on cerium inclusions in clean steels显示文摘To provide insights into deforming Ce-O-S-Al inclusions in steels and improving the mechanical properties,the evolution process of such harmful inclusions in clean steels was investigated by thermodynamic calculation,metallographic examination and first-principles calculation in this paper.For the tested IF steel,the thermodynamic analysis results are consistent with the calculated formation enthalpy.After Ce addition,the inclusions are transformed from Al_(2)O_(3)and TiN-Al_(2)TiO_(5)-Al_(2)O_(3)to Ce2O_(3),Ce_(2)O_(2)S,CeAlO_(3),TiN-Al_(2)TiO_(5)-Ce_(2)O_(3)and TiN-Al_(2)TiO_(5)-Ce_(2)O_(2)S composite inclusions,which can be confirmed by metallographic examination.The elastic constants were calculated,and the bulk modulus,Young's modulus,shear modulus and Poisson's ratio were evaluated by the Voigt-Reuss-Hill(VRH)approximation.All inclusions except Ce_(2)O_(3)show apparent brittleness.TiN,Al_(2)O_(3),Al_(2)TiO_(5)and CeAlO_(3)present much higher hardness than iron matrix,while the hardness of Ce2O_(3)or Ce_(2)O_(2)S is close to that of iron matrix.The thermal expansion coefficients of Ce_(2)O_(3)and CeAlO_(3)are close to that of iron matrix,whereas,Ce_(2)O_(2)S inclusion has largely different thermal expansion coefficient from iron matrix and may deteriorate the steel performance at higher temperatures.The relatively small differences between Ce inclusions and iron matrix in terms of hardness,toughness,brittleness,and thermal expansion coefficient can explain the improvement of the mechanical properties of the tested steel. | Xiangjun Liu Jichun Yang Fang Zhang Xiaoyang Fu Hongwei Li Changqiao Yang | 2021 | Journal of Rare Earths2021，39，4： | 6 |
| 15 | Performances of improved Tent chaos-based FM radar signal显示文摘A novel algorithm is proposed to solve the poor performance problem of the Tent chaos-based frequency modulation(FM) signal for range-Doppler imaging,which takes it into complex multi-segment system by increasing its segments.The simulation results show that the effectiveness of the proposed algorithm,as well as the performance of the improved Tent FM signal is obvious in a multipath or noise propagation environment. | Shaobin Xie Zishu He Jinfeng Hu Lidong Liu Jichun Pan | 2012 | Journal of Systems Engineering and Electronics2012，23，3： | 6 |
| 16 | Conditional QTL mapping of three yield components in common wheat(Triticum aestivum L.)显示文摘Spike number per m^2(SN),kernel number per spike(KNPS) and thousand-kernel weight(TKW)are the three main components determining wheat(Triticum aestivum L.) yield.To evaluate the relationships among them a doubled haploid(DH) population consisting of 168 lines grown at three locations for three years was analyzed by unconditional and conditional QTL mapping.Thirty-three unconditional QTL and fifty-nine conditional QTL were detected.Among them,two QTL(QSN-DH-2B and QSN-DH-3A-1.1) improved SN,with no effect on KNPS.QKNPS-DH-2B-2.1 improved KNPS,with no effect on SN.QKNPS-DH-1A-1.1,QKNPS-DH-2D-1.1and QKNPS-DH-6A improved KNPS,with no effect on SN or TKW.QKNPS-DH-6B was associated with increased SN and TKW.In addition,QTKW-DH-4B,QTKW-DH-5B and QTKW-DH-7B increased TKW without decreasing KNPS.These results provide useful information for marker assisted selection(MAS) and improvement in wheat yield. | Han Zhang Jiansheng Chen Ruyu Li Zhiying Deng Kunpu Zhang Bin Liu Jichun Tian | 2016 | The Crop Journal2016，4，3： | 5 |
| 17 | Study on the Metallogenetism of Sub-mantle Plume and Mantle Branches in the Gold Mineralization Concentration Area of Northwest Jiaodong Peninsula显示文摘The northwest of Jiaodong peninsula is characterized by its greatest gold concentration area, enormous gold reserves and limited time interval(115±5Ma) of gold mineralization in China. Studies show that the east area of north China began its mantle plume evolution since the Yanshanian movement, and the Laiyang sub-mantle plume and its surrounding mantle branches such as those in Guojiadian, Aishan and Panshidian were formed in the mineralization concentration area of northwestern Jiaodong peninsula. With the development of mantle plume → sub-mantle plume → mantle branch → favorable expending structures, the deep-derived hydrothermal fluid moved up to the favorable places, such as brittle-ductile or ductile-brittle shearing zones, the internal and external contact zones of intrusions, dense fracturing zones and the contact zones between dikes and countryrocks, and concentrated into deposits. Then the gold mineralization concentration zones that are centralized on mantle branches were formed. This study takes Guojiadian mantle branch as an example to discuss their metallogenetism and conclude the metallogenetic mode. | NIU Shuyin CHENG Guangsuo ZHANG Jianzhen SUN Aiqun MA Baojun ZHANG Fuxiang WANG Baode XU Meng WU Jichun ZHAO Rongxin WANG Shanfei | 2014 | Acta Geologica Sinica(English Edition)2014，88，5： | 4 |
| 18 | Isolation,Identification,and Characterization of an Aluminum-Tolerant Bacterium Burkholderia sp.SB1 from an Acidic Red Soil显示文摘Aluminum(Al) toxicity usually occurs in acidic soils worldwide, which is detrimental to the growth of organisms. An Al-tolerant bacterium, SB1, was isolated from an acidic red soil of Chingkang Mountain, located in Jiangxi Province of China. Polyphasic analysis,including a 16 S rDNA phylogenetic tree as well as morphological and physicochemical properties, revealed that the isolate was a gramnegative, rod-shaped bacterium, which was recognized as Burkholderia sp. SB1 and had extreme acidity tolerance(pH 2.2) and excellent Al resistance(270 mg L^(-1) Al^(3+)). It could remove Al by up to 97.7% at a concentration of 54 mg L^(-1) Al^(3+). SB1 behavior under different temperatures and antibiotics was also examined. SB1 preferred moderate temperature conditions, ranging from 25 to37?C, and exhibited notable resistance to multiple antibiotics(including ampicillin, streptomycin, and tetracycline), except for being sensitive to chloramphenicol. Therefore, as the first reported bacterium to possess favorable Al resistance and excellent Al removal,Burkholderia sp. SB1 can potentially be used as an agent for bioremediation of Al-contaminated acidic red soils. | HUANG Shoucheng WANG Xiaodong LIU Xu HE Genhe WU Jichun | 2018 | Pedosphere2018，28，6： | 4 |
| 19 | Prevalence of Cardiovascular Disease Risk Factor Clustering Among the Adult Population of China: Results From the International Collaborative Study of Cardiovascular Disease in Asia (InterAsia)显示文摘 | Dongfeng Gu Anjali Gupta Paul Muntner Shengshou Hu Xiufang Duan Jichun Chen Robert F. Reynolds Paul K. Whelton Jiang He | 2005 | Circulation2005，，5： | 4 |
| 20 | Non-fragile observer-based passive control for descriptor systems with time-delay显示文摘This paper investigates the problem of non-fragile observer-based passive control for descriptor systems with time-delay. The perturbations in both the control gain and observer gain of the observer-based controller are considered. For the cases of the additive perturbations and multiplicative perturbations, sufficient conditions are given such that the closed-loop systems are admissible and passive with dissipation η. The observer-based controller gains could be obtained from the solutions of linear matrix inequalities (LMIs). Moreover, the maximum dissipation of the system is provided. Simulation examples are given to show the effectiveness of the deign methods. | Qin LI Qingling ZHANG Jichun WANG | 2009 | 控制理论与应用(英文版)2009，7，3： | 4 |
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