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| 1 | Advances in ultra-high temperature ceramics,composites,and coatings显示文摘Ultra-high temperature ceramics(UHTCs)are generally referred to the carbides,nitrides,and borides of the transition metals,with the Group IVB compounds(Zr&Hf)and TaC as the main focus.The UHTCs are endowed with ultra-high melting points,excellent mechanical properties,and ablation resistance at elevated temperatures.These unique combinations of properties make them promising materials for extremely environmental structural applications in rocket and hypersonic vehicles,particularly nozzles,leading edges,and engine components,etc.In addition to bulk UHTCs,UHTC coatings and fiber reinforced UHTC composites are extensively developed and applied to avoid the intrinsic brittleness and poor thermal shock resistance of bulk ceramics.Recently,high-entropy UHTCs are developed rapidly and attract a lot of attention as an emerging direction for ultra-high temperature materials.This review presents the state of the art of processing approaches,microstructure design and properties of UHTCs from bulk materials to composites and coatings,as well as the future directions. | Dewei NI Yuan CHENG Jiaping ZHANG Ji-Xuan LIU Ji ZOU Bowen CHEN Haoyang WU Hejun LI Shaoming DONG Jiecai HAN Xinghong ZHANG Qiangang FU Guo-Jun ZHANG | 2022 | Journal of Advanced Ceramics2022，11，1： | 9 |
| 2 | Phase I study of CAR-T cells with PD-1 and TCR disruption in mesothelin-positive solid tumors显示文摘Programmed cell death protein-1(PD-1)-mediated immunosuppression has been proposed to contribute to the limited clinical efficacy of chimeric antigen receptor T(CAR-T)cells in solid tumors.We generated PD-1 and T cell receptor(TCR)deficient mesothelin-specific CAR-T(MPTK-CAR-T)cells using CRISPR-Cas9 technology and evaluated them in a dose-escalation study.A total of 15 patients received one or more infusions of MPTK-CAR-T cells without prior lymphodepletion.No dose-limiting toxicity or unexpected adverse events were observed in any of the 15 patients.The best overall response was stable disease(2/15 patients).Circulating MPTK-CAR-T cells peaked at days 7–14 and became undetectable beyond 1 month.TCR-positive CAR-T cells rather than TCR-negative CAR-T cells were predominantly detected in effusion or peripheral blood from three patients after infusion.We further confirmed the reduced persistence of TCR-deficient CAR-T cells in animal models.Our results establish the preliminary feasibility and safety of CRISPR-engineered CAR-T cells with PD-1 disruption and suggest that the natural TCR plays an important role in the persistence of CAR-T cells when treating solid tumors. | Zhenguang Wang Na Li Kaichao Feng Meixia Chen Yan Zhang Yang Liu Qingming Yang Jing Nie Na Tang Xingying Zhang Chen Cheng Lianjun Shen Jiaping He Xun Ye Wei Cao Haoyi Wang Weidong Han | 2021 | Cellular & Molecular Immunology2021，18，9： | 7 |
| 3 | Corporate precautionary cash holdings显示文摘 | Seungjin Han Jiaping Qiu | 2006 | Journal of Corporate Finance2006，，1： | 5 |
| 4 | Corporate Precautionary Cash Holdings 显示文摘 | Han Seungjin Jiaping Qiu | 2007 | Journal of Corporate Finance2007，13，1： | 1 |
| 5 | Hopping con- duction in Mn-doped ZnO 显示文摘 | Han Jiaping Shen Mingrong Cao Wenwu | 2003 | Appl Phys Lett2003，82，： | 1 |
| 6 | Self-cleaning property of AZ31 Mg alloy during plasma electrolytic oxidation process显示文摘The rolling of metal sheet often leads to strong contamination of the resulting surface. The present work reports the effects of the surface contamination remaining after rolling of AZ31 Mg alloy on plasma electrolytic oxidation(PEO) treatment of the resulting sheet material. Results indicate that most of the contaminants on the surface of as-rolled AZ31 Mg alloy are removed in the early stages of PEO process. The contaminations slightly influence the phase composition of PEO coating. Non-uniform distribution of contaminations results in aggregation of pores on the surface of PEO samples. On the bare substrate the contaminations are responsible for poor wear and corrosion resistance but final PEO coatings reveals similar performance on contaminated substrate compared to the abraded one. A self-cleaning property of the PEO and possibility of one step process,avoiding pre-cleaning stages, is suggested. | Jiaping Han Carsten Blawert Junjie Yang Xiaopeng Lu Jin Hu Mikhail L.Zheludke vich | 2019 | Progress in Natural Science:Materials International2019，29，1： | 1 |
| 7 | Corporate Precautionary cash holdings 显示文摘 | HAN SEUNGJIN QIU JIAPING | 2007 | Journal of Corporate Finance2007，，13： | 1 |
| 8 | Corporate precautionary cash holdings显示文摘 | Han S Qiu Jiaping | 2007 | Journal of Corporate Finance2007，13，1： | 1 |
| 9 | Varistor behaviour of Mn-doped ZnO ceramics显示文摘 | HAN Jiaping SENOS A M R MANTAS P Q | 2002 | Journal of the European Ceramic Society:2002，22，910： | 1 |
| 10 | Corporate Precautionary Cash Holdings 显示文摘 | Han Seungjin Jiaping Qiu | 2007 | Journal of Corporate Finance2007，，13： | 1 |
| 11 | Corporate precautionary cash holdings显示文摘 | Seungjin Han Jiaping Qiu | 2006 | Journal of Corporate Finance2006，，1： | 1 |
| 12 | , Corporate precautionary cash holdings 显示文摘 | Seungjin Han Jiaping Qiu | 2007 | Journal of Corporate Finance2007，，13： | 1 |
| 13 | Analysis of Compressive Strength Development of Ultra-high Performance Concrete显示文摘A numerical procedure was presented for evaluating the compressive strength development of ultra-high performance concrete(UHPC) with cement-silica fume-slag binder.This numerical procedure started with initial packing behavior of designed UHPC using a random sequential packing method.Furthermore,synergistic effect of combined mineral admixtures was addressed with respect to hydration heat.Accordingly,hydration degree of cement and reaction degrees of mineral admixtures were determined based on a blended cement hydration model.Finally,a compressive strength evolution model was proposed and the evolution of compressive strength of three mixes with different binder recipes was compared.The results showed that the both initial packing behavior of UHPC mixes and synergistic effect of mineral admixtures are critical for predicting the properties of UHPC.A remarkable void fraction of 0.2042 was observed for UHPC mix designed by optimization algorithms under random packing.Furthermore,a negative synergistic effect of the combination of silica fume and slag was obtained with regarding to compressive strength.In addition,for a given mineral admixture replacement of 20%,the formulation of mineral admixture should be carefully tailored where the UHPC incorporating 5%silica fume and 15%slag shows the highest compressive strength. | HAN Fangyu LIU Jianzhong ZHANG Qianqian LIU Jiaping SHI Liang | 2016 | Journal of the Chinese Ceramic Society2016，，3： | 0 |
| 14 | Organophosphine ligand derived sandwich-structural electrocatalyst for oxygen evolution reaction显示文摘The synchronous construction of metal phosphate and phosphorus-doped carbon structures is of great significance to innovate the design,synthesis,and application of catalysts,as these phosphoruscontaining composite materials have shown a remarkable contribution to electrocatalysts.However,their preparation procedure generally involves using large amounts of excess phosphorus sources for phosphorization,which inevitably release poisonous PH_(3) or dangerous phosphorus vapor.Here,a strategy for in-situ formation of FePO_(4) embedded in P-doped carbon 2D nano film(FePO_(4)/PdC)is developed using a highly integrated precursor,which is a small molecular organophosphine ligand,1,1’bis(diphenylphosphine)ferrocene(DPPF).The multi-source precursor DPPF that contains Fe,P,and C is molecular-vapor-deposited on the nickel foam(NF)supported ZIF-67 nanosheets to obtain the composite catalyst,namely DPPF-500/ZIF-67/NF.FePO_(4)/PdC encapsulated the ZIF-67 derived Co/N-doped carbon matrix(Co NC)to form a sandwich structure FePO_(4)/PdC@CoNC.The constructed catalyst shows good performance for OER,requiring an overpotential of only 297 m V to deliver 600 m A/cm^(2) with a Tafel slope of 42.7 m V dec^(-1).DFT calculations demonstrate that the synergistic effects between the metal active center and P-doped carbon film reduce the energy barriers and improve electron transport.This method of constructing P-containing catalysts overcomes the demand for additional P sources to realize eco-friendly fabrication and yields a unique structure with good catalytic activity. | Zejun Sun Wenjuan Xu Liutao Guo Qiang Han Jianyi Gao Jiaping Wang Yanru Feng Chengrui Li Qionglin Liang Hong-bin Sun Yang Yang | 2022 | Journal of Energy Chemistry2022，31，7： | 0 |
| 15 | Preface to Special Topic on Atmospheric Greenhouse Gas Measurement and Application in China显示文摘China initiated a national carbon trading market in December 2017.Commitments and actions to reduce greenhouse gas(GHG)emissions require consistent,reliable and timely information on GHG emissions.GHG monitoring and modeling studies provide GHG emission estimates to evaluate and guide progress towards emission reductions.GHG monitoring has mainly focused on global-scale background networks over the last few decades,while recent efforts have been made on regional and urban scales,such as projects in the Beijing-Tianjin-Hebei city cluster,in Paris,Washington-Baltimore. | Pengfei HAN Ning ZENG Bo YAO Weijian ZHOU Liqi CHEN Shaoqiang WANG Honggang LV Wei XIAO Lingyun ZHU Jiaping XU | 2020 | Advances in Atmospheric Sciences2020，37，6： | 0 |
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