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| 1 | Effects of Long-Term Combined Application of Organic and Mineral Fertilizers on Microbial Biomass,Soil Enzyme Activities and Soil Fertility显示文摘土壤健康为陆上的生态系统的持续发展是重要的。在这篇论文,我们学习了在土壤质量和土壤之间的关系微生物引起的性质例如玷污微生物引起的生物资源和土壤酶活动以便说明功能作为土壤健康的简历指示物玷污微生物引起的性质。在这研究,微生物引起的生物资源 C 和 N 内容(Cmic 与 Nmic ) 。有不同化肥政体的土壤酶活动,和土壤肥力在 Changping 县在娼妓 Fluvo-aquic 土壤基于一个 15 年的长期的化肥实验被执行,中国北京。在这个地点, 7 个不同处理在 1991 被建立。他们也不在小麦玉米旋转正在收到化肥(CK ) 。矿质肥料(NPK ) 。有合并的麦秸(NPKW+) 的矿质肥料,有合并的增长麦秸(NPKW+) 的矿质肥料,加猪粪肥(NPKM ) 的矿质肥料,加增长的猪粪肥(NPKM+) 的矿质肥料或有合并的玉米秸秆(NPKS ) 的矿质肥料。在不同授精处理, Cmic 从 96.49 ~ 500.12 mg kg 变化了 ? 1,并且 Nmic 从 35.89 ~ 101.82 mg kg 变化了 ? 1。与 CK 相比,另外的处理增加了 Cmic 与 Nmic, Cmic/Corg (器官的 C ) 比率, Cmic/Nmic,脲酶活动,土壤有机物(SOM ) 。土壤总氮(STN ) ,和土壤总数磷(STP ) 。在有化肥输入 NPKM+ 的处理的所有这些性质最高。同时,有有机肥料或庄稼稻草的矿质肥料的长期的联合申请能显著地减少在 Fluvo-aquic 土壤(在这试验性的土壤的在 8.00 附近的 pH ) 的土壤 pH。一些土壤微生物引起的性质(Cmic/Nmic。脲酶活动) 断然与土壤营养素被相关。Cmic/Nmic 显著地与 SOM 和 STN 内容被相关。在过氧化氢酶活动和土壤营养素之间的关联不是重要的。除了过氧化氢酶活动,另外,在这个实验的土壤 pH 否定地与土壤被相关微生物引起的性质。在结论,微生物引起的性质反映的土壤土壤质量并且这样变化能被用作土壤健康的简历指示物。 | LI Juan ZHAO Bing-qiang LI Xiu-ying JIANG Rui-bo So Hwat Bing | 2008 | Agricultural Sciences in China2008，7，3： | 49 |
| 2 | Role of Contrast-enhanced Ultrasound in the Evaluation of Inflammatory Arthritis显示文摘 | Chen-Yang Zhao Yu-Xin Jiang Jian-Chu Li Zhong-Hui Xu Qing Zhang Na So Meng Yang | 2017 | Chinese Medical Journal2017，，14： | 13 |
| 3 | A potential oncogenic role of the commonly observed E2F5 overexpression in hepatocellular carcinoma显示文摘AIM: To explore the expression pattern of E2F5 in primary hepatocellular carcinomas (HCCs) and elucidate the roles of E2F5 in hepatocarcinogenesis. METHODS: E2F5 expression was analyzed in 120 primary HCCs and 29 normal liver tissues by immunohistochemistry analysis. E2F5-small interfering RNA was transfected into HepG2, an E2F5-overexpressed HCC cell line. After E2F5 knockdown, cell growth capacity and migrating potential were examined. RESULTS: E2F5 was significantly overexpressed in primary HCCs compared with normal liver tissues (P = 0.008). The E2F5-silenced cells showed significantly reduced proliferation (P = 0.004). On the colony formation and soft agar assays, the number of colonies was significantly reduced in E2F5-silenced cells (P = 0.004 and P = 0.009, respectively). E2F5 knockdown resulted in the accumulation of G0/G1 phase cells and a reduction of S phase cells. The number of migrating/invading cells was also reduced after E2F5 knockdown (P = 0.021). CONCLUSION: To our knowledge, this is the first evidence that E2F5 is commonly overexpressed in primary HCC and that E2F5 knockdown significantly repressed the growth of HCC cells. | Yuzhu Jiang Seon-Hee Yim Hai-Dong Xu Seung-Hyun Jung So Young Yang Hae-Jin Hu Chan-Kwon Jung Yeun-Jun Chung | 2011 | World Journal of Gastroenterology2011，17，4： | 10 |
| 4 | Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway显示文摘Whether and how garlic-derived S-allylmercaptocysteine(SAMC) inhibits hepatocellular carcinoma(HCC) is largely unknown. In the current study, the role of low-density lipoprotein receptor(LDLR)-related protein 6(LRP6) in HCC progression and the anti-HCC mechanism of SAMC was examined in clinical sample, cell model and xenograft/orthotopic mouse models. We demonstrated that SAMC inhibited cell proliferation and tumorigenesis, while induced apoptosis of human HCC cells without influencing normal hepatocytes. SAMC directly interacted with Wnt-pathway co-receptor LRP6 on the cell membrane. LRP6 was frequently over-expressed in the tumor tissue of human HCC patients(66.7% of 48 patients) and its overexpression only correlated with the over-expression of β-catenin, but not with age, gender, tumor size, stage and metastasis. Deficiency or over-expression of LRP6 in hepatoma cells could partly mimic or counteract the anti-tumor properties of SAMC, respectively. In vivo administration of SAMC significantly suppressed the growth of Huh-7 xenograft/orthotopic HCC tumor without causing undesirable side effects. In addition, stable down-regulation of LRP6 in Huh-7 facilitated the anti-HCC effects of SAMC. In conclusion, LRP6 can be a potential therapeutic target of HCC. SAMC is a promising specific anti-tumor agent for treating HCC subtypes with Wnt activation at the hepatoma cell surface. | Jia Xiao Feiyue Xing Yingxia Liu Yi Lv Xiaogang Wang Ming-Tat Ling Hao Gao Songying Ouyang Min Yang Jiang Zhu Yu Xia Kwok-Fai So George L.Tipoe | 2018 | Acta Pharmaceutica Sinica B2018，8，4： | 6 |
| 5 | Persistent per- fluorinated acids in seafood collected from two cities of China 显示文摘 | Gulkowska A Jiang Q T So M K | 2006 | Environmental Science & Technology2006，40，12： | 1 |
| 6 | Discovery of (2,3-difluoro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity显示文摘 | Chu XJ DePinto W Bartkovitz D So SS Vu BT Packman K Lukacs C Ding Q Jiang N Wang K Goelzer P Yin X Smith MA Higgins BX Chen Y Xiang Q Moliterni J Kaplan G Graves B Lovey A Fotouhi N | 2006 | J Med Chem2006，49，22： | 1 |
| 7 | Perfluorooctanesulfonateand related fluorochemicals in human blood samplesfrom China显示文摘 | YEUNG L W Y SO M K JIANG G | 2006 | Environmental Science and Technology2006，40，3： | 1 |
| 8 | Perfluorooctane sulfonate andrelated fluorochemicals in human blood samples from China显示文摘 | Yeung L W Y So M K Jiang G B | 2006 | Envi-ronmental Science and Technology2006，40，3： | 1 |
| 9 | Peptide photocaging:A brief account of the chemistry and biological applications显示文摘Light is arguably the most convement non-invasive stimulant to perturb or control specinc cnemical reactions in the biological systems. Upon light illumination, photosensitive molecules incur conformational changes or formation/breaking of chemical bonds. Consequently, these molecules can be used to transfer signals from one location to another in the cell, from outside of the cell to the inside, or from a light bulb to the interior of animal tissues. The development of the photochemical reactions of organic compounds has paved the road towards their use in peptides and peptide-based biological applications. In this mini-review, we summarized the state-of-the-art development of photo-protecting groups for peptide photocaging including the un-caging mechanism of different PPGs, the synthesis of photo-caged peptides, and the recent applications of peptide photocaging in chemical biology. | Wing Ho So Clarence T.T.Wong Jiang Xia | 2018 | Chinese Chemical Letters2018，29，7： | 1 |
| 10 | The value of strain ratio in differential diagnosis of thyroid solid nodules显示文摘 | Ning CP Jiang SO Zhang T etal | 2012 | Eur J Radiol2012，81，2： | 1 |
| 11 | Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells显示文摘 | Huang Y Kim SO Jiang J | 2003 | J Biol Chem2003，278，18： | 1 |
| 12 | ,Perfluorooetane sulfonate and related Fluorochemicals in human bloods samples from China显示文摘 | Yeung LWY So MK Jiang GB | 2006 | Env- iron Sci Technol2006，40，3： | 1 |
| 13 | ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2显示文摘 | Park SO Lee YJ Seki T Hong KH Fliess N Jiang Z | 2008 | Blood2008，111，2： | 1 |
| 14 | Persistent perfluorinated acids in seafood collected from two cities of China显示文摘 | Gulkowska A Jiang Q So M K | 2006 | Environmental Science&Technology2006，40，12： | 1 |
| 15 | Automation of an optical time domain reflectometer to measure loss and return loss显示文摘 | SO V C Y JIANG J W CARGILL J A | 1990 | J Lightw Technol1990，8，7： | 1 |
| 16 | The value of strain ratio in differential diagnosis of thyroid solid nodules显示文摘 | Ning CP Jiang SO Zhang T | 2012 | Eur J Radiol2012，81，2： | 1 |
| 17 | Persistent perfluorinated acids in seafood collected from two cities of China显示文摘 | GULKOWSKA A JIANG Q T SO M K | 2006 | Environmental Science & Technology2006，40，12： | 1 |
| 18 | Simulation of cross-flow-induced vibration of cylinder arrays by surface vorticity method 显示文摘 | Lam K Jiang G D Liu Y So R M C | 2006 | Journal of Fluids and Structures2006，22，： | 1 |
| 19 | Perfluorooctane sulfonate and related fluorochemicals in human blood samples from China 显示文摘 | Yeung L W So M K Jiang G | 2006 | Environmental Science & Tech- nology2006，40，3： | 1 |
| 20 | Perfluorooctanesulfonate and related fluorochemicals in human blood samples from China显示文摘 | YEUNG L W Y SO M K JIANG G B | 2006 | Environ Sci Technol2006，40，3： | 1 |
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