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| 1 | Metal Fabrication by Additive Manufacturing Using Laser and Electron Beam Melting Technologies显示文摘Selective laser melting (SLM) and electron beam melting (EBM) are relatively new rapid, additive manufac- turing technologies which can allow for the fabrication of complex, multi-functional metal or alloy monoliths by CAD-directed, selective melting of precursor powder beds. By altering the beam parameters and scan strategies, new and unusual, even non-equilibrium microstructures can be produced; including controlled microstructural architectures which ideally extend the contemporary materials science and engineering paradigm relating structure-properties-processing-performance. In this study, comparative examples for SLM and EBM fabricated components from pre-alloyed, atomized precursor powders are presented. These include Cu, Ti–6Al–4V, alloy 625 (a Ni-base superalloy), a Co-base superalloy, and 17-4 PH stainless steel. These systems are characterized by optical metallography, scanning and transmission electron microscopy, and X-ray diffraction. | Lawrence E. Murr Sara M. Gaytan Diana A. Ramirez Edwin Martinez Jennifer Hernandez Krista N. Amato Patrick W. Shindo Francisco R. Medina Ryan B. Wicker | 2012 | Journal of Materials Science & Technology2012，28，1： | 98 |
| 2 | A System for Continual Quality Improvement of Normal Tissue Delineation for Radiation Therapy Treatment Planning显示文摘 | Jennifer Breunig Sophy Hernandez Jeffrey Lin Stacy Alsager Christine Dumstorf Jennifer Price Jennifer Steber Richard Garza Suneel Nagda Edward Melian Bahman Emami John C. Roeske | 2012 | International Journal of Radiation Oncology Biology Physics2012，，5： | 1 |
| 3 | RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors显示文摘 | Theresa M. Ballard Frédéric Knoflach Eric Prinssen Edilio Borroni Jeffrey A. Vivian Jennifer Basile Rodolfo Gasser Jean-Luc Moreau Joseph G. Wettstein Bernd Buettelmann Henner Knust Andrew W. Thomas Gerhard Trube Maria-Clemencia Hernandez | | Psychopharmacology (-)0，，： | 1 |
| 4 | Evaluation of steroidogenic capacity after follicle stimulating hormone stimulation in bovine granulosa cells of Revalor 200~ implanted heifers显示文摘Background:Heifers not used as breeding stock are often implanted with steroids to increase growth efficiency thereby altering hormone profiles and potentially changing the environment in which ovarian follicles develop.Because bovine granulosa cell culture is a commonly used technique and often bovine ovaries are collected from abattoirs with no record of implant status,the objective of this study was to determine if the presence of an implant during bovine granulosa cell development impacts follicle stimulating hormone-regulated steroidogenic enzyme expression.Paired ovaries were collected from 16 feedlot heifers subjected to 1 of 3 treatments:non-implanted(n = 5),Revalor 200 for 28 d(n = 5),or Revalor 200 for 84 d(n = 6).Small follicle(1 to 5 mm)granulosa cells were isolated from each pair and incubated with phosphate buffered saline(n = 16) or 100 ng/mL follicle stimulating hormone(n = 16) for 24 h.Results:Granulosa cells of implanted heifers treated with follicle stimulating hormone produced medium concentrations of progesterone similar(P = 0.22) to non-implanted heifers,while medium estradiol concentrations were increased(P<0.10) at 28 and 84 d compared to non-implanted heifers indicating efficacy of treatment.Additionally,real-time PCR analysis in response to follicle stimulating hormone treatment demonstrated a decrease in steroidogenic acute regulatory protein(P = 0.05) mRNA expression in heifers implanted for 84 d and an increase in P450 side chain cleavage mRNA in granulosa cells of heifers implanted for 28(P< 0.10) or 84 d(P< 0.05)compared to non-implanted females.However,no difference in expression of 3-beta-hydroxysteroid dehydrogenase(P = 0.57) and aromatase(P = 0.23) were demonstrated in implanted or non-implanted heifers.Conclusions:These results indicate follicles which develop in the presence of high concentrations of androgenic and estrogenic steroids via an implant tend to demonstrate an altered capacity to respond to follicle stimulating hormone stimulation.Thus,efforts should be made to avoid the use of implanted heifers to study steroidogenesis in small follicle granulosa cell culture systems. | ANDrea D Stapp Craig A Gifford Dennis M Hallford Jennifer A Hernandez Gifford | 2014 | Journal of Animal Science and Biotechnology2014，5，3： | 0 |
| 5 | 史密森南广场园区规划显示文摘通过与史密森学会、当地居民以及决策者的密切合作,我们为南广场园区制定了总体规划,作为对旧与新的重新诠释——方案利用园区内的现有元素,在严格监管与历史保护的限制中寻求自由。该提案旨在提升并扩大游客服务和教育空间,在博物馆与花园之间建立清晰的入口和联系,并取代已达到使用寿命的老化建筑机械系统。 | Aaron Hales Alana Goldweit Alexandre Hamlyn Andriani Atmadja Annette Miller Benjamin DiNapoli Benjamin Novacinski Cadence Bayley Choonghyo Lee Chris Falla Daisy Zhong Daniele Pronesti Doug Stechschulte Emily Chen Gabriel Hernandez Solano Janice Rim Jennifer Shen Jeremy Alain Siegel Jihoon Hyun Julian Andres Ocampo Salazar Kalina Pilat Katarzyna Starczewska Lina Bondarenko Mahsa Malek Manon Otto Martin Voelkle Ola Hariri Otilia Pupezeanu Saecheol Oh Sara Ibrahim Stephen Kwok Stephen Steckel Suemin Jeon Tammy Teng Taylor Fulton Tianqi Zhang Vincent Fulia Wells Barber Wesley Chiang Zhifei Xu 陈子钰(译) | 2019 | 城市环境设计2019，0，2： | 0 |
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