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| 1 | Apoptosis,antimicrobial and antioxidant activities of phytochemicals from Garcinia malaccensis Hk.f显示文摘Objective:To study the chemical constituents of stembark of Garcinia malaccenm(G.malaccenm) together with apoptotic.antimicrobial and antioxidant activities.Methods:Purification and structure elucidation were carried out by chromatographic and spectroscopic techniques, respectively.MTT and trypan blue exclusion methods were performed to study the cytotoxic activity.Antibacterial activity was conducted by dise diffusion and microdilulion methods, whereas antioxidant activities were done by ferric thiocyanate method and DPPH radical scavenging.Results:The phylochemical study led lo the isolation ofα,β-mangostin and cycloarl-24-en-3β-ol.α-Mangostin exhibited cytotoxic activity against HSC-3 cells with an IC50 of 0.33μM.β- andα-mangostin showed activity against K562 cells with IC50 of 0.40μM and 0.48μM,respectively,α-Mangostin was active against Gram-positive bacteria, Staphylococcus aureus(S.aureus) and Bacilus anthracis(B.anthmcis) with inhibition zone and MIC value of(19 mm;0.02S mg/mL) and(20 mm;0.013 mg/mL),respectively.In antioxidant assay,α-mangostin exhibited activity as an inhibitor of lipid peroxidation.Conclusions:G.malaccenm presenceα- andβ-mangostin and cycloart-24-en-3β-ol.β-Mangostin was found very active against H.SC-3 cells and KS62.The results suggest that mangoslins derivatives have the potential to inhibit the growth of cancer cells by inducing apoptosis.In addition,α-andβ-mangostin was found inhibit the growth of Cram-positive pathogenic bacteria and also showed the activity as an inhibitor of lipid peroxidation. | Muhammad Taher Deny Susanti Mohamad Fazlin Rezali Farah Syahidah Ahmad Zohri Solachuddin Jauhari Arief Ichwan Suhaib Ibrahim Alkhamaiseh Farediah Ahmad | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，2： | 5 |
| 2 | Comparison of surgically induced astigmatism in various incisions in manual small incision cataract surgery显示文摘AIM: To determine the surgically induced astigmatism(SIA) in Straight, Frown and Inverted V shape(Chevron)incisions in manual small incision cataract surgery(SICS).METHODS: A prospective cross sectional study was done on a total of 75 patients aged 40 y and above with senile cataract. The patients were randomly divided into three groups(25 each). Each group received a particular type of incision(Straight, Frown or Inverted V shape incisions). Manual SICS with intraocular lens(IOL)implantation was performed. The patients were compared4 wk post operatively for uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA) and SIA. All calculations were performed using the SIA calculator version 2.1, a free software program. The study was analyzed using SPSS version 15.0 statistical analysis software.RESULTS: The study found that 89.5% of patients in Straight incision group, 94.2% in Frown incision group and 95.7% in Inverted V group attained BCVA post-operatively in the range of 6/6 to 6/18. Mean SIA was minimum(-0.88 ±0.61 D ×90 degrees) with Inverted V incision which was statistically significant.CONCLUSION: Inverted V(Chevron) incision gives minimal SIA. | Nidhi Jauhari Deepak Chopra Rajan Kumar Chaurasia Ashutosh Agarwal | 2014 | International Journal of Ophthalmology(English edition)2014，7，6： | 2 |
| 3 | Nutraceuticals as potential therapeutic agents for colon cancer: a review显示文摘Colon cancer is a world-wide health problem and the second-most dangerous type of cancer,affecting both men and women.The modern diet and lifestyles,with high meat consumption and excessive alcohol use,along with limited physical activity has led to an increasing mortality rate for colon cancer worldwide.As a result,there is a need to develop novel and environmentally benign drug therapies for colon cancer.Currently,nutraceuticals play an increasingly important role in the treatment of various chronic diseases such as colon cancer,diabetes and Alzheimer's disease.Nutraceuticals are derived from various natural sources such as medicinal plants,marine organisms,vegetables and fruits.Nutraceuticals have shown the potential to reduce the risk of colon cancer and slow its progression.These dietary substances target different molecular aspects of colon cancer development.Accordingly,this review briefly discusses the medicinal importance of nutraceuticals and their ability to reduce the risk of colorectal carcinogenesis. | Palaniselvam Kuppusamy Mashitah M.Yusoff Gaanty Pragas Maniam Solachuddin Jauhari Arief Ichwan Ilavenil Soundharrajan Natanamurugaraj Govindan | 2014 | Acta Pharmaceutica Sinica B2014，4，3： | 2 |
| 4 | Drag coeffi- cients for air bubbles rising along an inclined surface显示文摘 | MASLIYAH J JAUHARI R GRAY M | 1994 | Chemical Engineering Science1994，49，12： | 1 |
| 5 | Double-ion imprinted polymer @ magnetic nanoparticles modified screen printed carbon electrode for simultaneous analysis of cerium and gadolinium ions 显示文摘 | Bhim Bali Prasad Darshika Jauhari | 2015 | Ana- lytiea Chimica Acta2015，875，： | 1 |
| 6 | Quantitation of T cells in venous blood of healthy neonates显示文摘 | Ashok Kumar Praveen Jauhari Usha Singh P. N. Singla | 1994 | The Indian Journal of Pediatrics1994，，6： | 1 |
| 7 | Altitudinal distribution of mosquitoes in mountainous area of Garhwal region: Part- l 显示文摘 | Devi NP Jauhari RK | 2004 | J Vect Borne Dis2004，41，： | 1 |
| 8 | Improving surface properties and wear behaviors of duplex stainless steel via pressure carburizing显示文摘 | Sharidah Azuar Abdul Azis Iswadi Jauhari Nor Wahida Ahamad | 2012 | Surface & Coatings Technology2012，，： | 1 |
| 9 | Superplastic Bo- ronizing of Duplex Stainless Steel under Dual Compression Method显示文摘 | JAUHARI I YUSOF H A M SAIDAN R | 2011 | Materials Science and Engineering2011，528，28： | 1 |
| 10 | Endoscopic vein harvesting in lower extremity arterial bypass: a systematic review 显示文摘 | Jauhari YA Hughes CO Black SA | 2014 | Eur J Vase Endovasc Surg2014，47，6： | 1 |
| 11 | Biological productivity, terrigenous influence and noncrustal elements supply to the Central Indian Ocean Basin: Paleoceanography during the past ~ 1 Ma显示文摘 | J. N. Pattan Toshiyuki Masuzawa D. V. Borole G. Parthiban Pratima Jauhari Mineko Yamamoto | 2005 | Journal of Earth System Science2005，，1： | 1 |
| 12 | Exploring Consumer Attitude and Behaviour Towards Green Practices in the Lodging Industry In India显示文摘 | Manaktola K Jauhari V | 2007 | International Journal of Contemporary Hospitality Management2007，19，5： | 1 |
| 13 | Optimum sampling in- terval for evaluating ferromang anese nodule resources in the central Indian ocean显示文摘 | Jauhari P Kodagali V N Sankar S J | 2001 | Geo Marine Letters2001，21，： | 1 |
| 14 | Abnormal immunoreactivity of the E-cadherin-catenin complex in gastric carcinoma: relationship with patient survival显示文摘 | Jauhari A Jordan S Poole S | 1997 | Gastroenterology1997，112，： | 1 |
| 15 | Experi- mental and theoretical, investigation o{ 2 mercaptoquin oline-g-carbaldehyde and its schiff base as an inhibitor of mild steel in 1M HC1显示文摘 | MISTRY B M SAHOO S K JAUHARI S | 2013 | Journal of Electroanalyti- cal Chemistry2013，7，： | 1 |
| 16 | Structures of three new diterpenes,coleonol-B,coleonol-C & deoxycoleonol isolated from Coleus forskohlii显示文摘 | Jauhari PK Singh RS | 1978 | Indian J of Chem1978，16，5： | 1 |
| 17 | 显示文摘 | Surati M A Jauhari S Desai K R | 2012 | Arch Appl Sci Res2012，4，1： | 1 |
| 18 | A cellulase-poor, thermostable, alkalitalerant xylanase produced by Aacillus circulans AB 16 grown on rice straw and its application in biobleaching of eucalyptus pulp显示文摘 | Dhillon A Gupta J K Jauhari B M | 2000 | Bioresource Technology2000，73，： | 1 |
| 19 | A celluase-poor,thermostable,alkalitolerant xylanase produced by Bacillus circulans AB16 grown on rice straw ans its application in biobleaching of eucalyptus pulp显示文摘 | Ashita D Gupta JK Jauhari BM | 2000 | Bioresource Technology2000，73，： | 1 |
| 20 | Exploring consumer attitude and behavior towards green practices in the lodging industry in India 显示文摘 | Kamal Manaktola Vinnie Jauhari | 2007 | International Journal of Contemporary Hospitality Management2007，19，5： | 1 |
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