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| 1 | Involvement of gene expressions in apoptosis of vascularendothelial cells induced by rattlesnake venom显示文摘Formation of apoptotic bodies is a typical character ofaPoptotic cell death, but how the processes are controlledis not known. In this study, we compared two apoptosisinducing systems in vascular endothelial cells (VEC). Wefound that the formation of aPoptotic bodies during apop-tosis induced by rattlesnake venom, which is an unique andspecific aPoptosis inducer to vascular endotheliaI cells, wasmuch faster than that induced by deprivation of survivalfactors (aFGF and serum). When we blocked the synthesisof mRNAs in cells treated with rattlesnake venom by DRB(5, 6- dichloro- 1 -β- D- rib ofur anosylb enzimidazole ), an in-hibitor of transcription, the formation of aPoptotic bodieswas dramatically inhibited. We examined the expressionof Psa gene and found that its expression was much higherin apoptosis induced by rattlesnake venom than that inaPoptosis induced by deprivation of aFGF and serum. Ourresults suggest that gene expression is important and P53gene may play a major role in inducing the formation ofapoptotic bodies in VEC. | MIAO JUN YING SATOHIKO ARAKI YI RENHAN HIROSHI HAYASHI(Institute of DeveloPmental Biology, School of Life Sci-ence, Shandong University, Jinan 250100, China)(Sugashima Marine BiolOgical Labomtory, School of Sci-ence, Nagoya University, To6a, Me, 517 Japa | 1999 | Cell Research1999，9，3： | 3 |
| 2 | Cytochrome P4502C9 activity in end-stage renal disease 显示文摘 | Dreisbach AW Japa S Gebrekal AB | 2003 | Clin Pharmacol Ther2003，73，5： | 1 |
| 3 | Blood histamine is associat- ed with coronary artery disease, cardiac events and severity of in- flammation and atherosclerosis显示文摘 | Clejan S Japa S Clemetson C | 2002 | J Cell Mol Med2002，6，4： | 1 |
| 4 | High pressure phase equilibrium and PVT-data of the water-oxygen system including water-air to 673 K and 250 MPa显示文摘 | Japas Maria L Franck E U | 1985 | Berichte der Bunsengesellschaft für Physikalische Chemie1985，89，12： | 1 |
| 5 | Using EEG spectral components to assess algorithms for detecting fatigue显示文摘 | Japa BT Lal S Fiseher P | 2009 | Expert Syst Appl2009，36，2： | 1 |
| 6 | Cytochrome 17450 2C9 Activity in Eng-Stagerenal Disease 显示文摘 | Dreisbach AW Japa S Gebrekal AB et M | 2003 | Glin Pharmacol Ther2003，73，5： | 1 |
| 7 | High-pressure phase-equilibria and PVTdata of the water-oxygen system including water-air to 673 K and 250 MPa显示文摘 | Japas M L Franck E U | 1985 | Berichte der Bunsen-Gesellschaft-Physical Chemistry Chemical Physics1985，89，12： | 1 |
| 8 | The prevalence of CYP2C8,2C9,2J2,and soluble epoxide hydrolase polymorphisms in African Americans with hypertension显示文摘 | Dreisbach A W JapaS Sigel A | 2005 | American Journal of Hypertension2005，18，10： | 1 |
| 9 | Using EEG spectral components to assess algorithms for detecting fatigue显示文摘 | Japa B T Lal S Fischer P | | 0，，： | 1 |
| 10 | Guidelines for diagnosis and management of cardiovascular sequelae in Kawasaki disease显示文摘 | Japaness Circulation Society Joint Research Group | 2005 | Pediatr Int2005，47，6： | 1 |
| 11 | Detection of bacterial DNA in Latin American patients with reactive arthritis by polymerasechain reaction and sequencing analysis 显示文摘 | Japa S Huang WQ | 2002 | J Rheumatol2002，29，7： | 1 |
| 12 | Cost-effectiveness of statins for primary cardiovascular prevention in chronic kidney disease 显示文摘 | Erickson KF Japa S Owens DK | 2013 | J Am Coil Cardiol2013，61，12： | 1 |
| 13 | Surgical treatment of pes cavus by tarsal V-osteotomy显示文摘 | | 1968 | J Bone Joint Surg (Am)1968，50，： | 1 |
| 14 | Cost-effectiveness of statins for primary cardiovascular prevention in chronic kidney disease显示文摘 | Erickson KF Japa S Owens DK | 2013 | J Am Coll Cardiol2013，61，12： | 1 |
| 15 | Guidelines for diagnosis and management of cardiovascular sequelae in Kawasaki disease 显示文摘 | Japaness Circulation Society Joint Research Group | 2005 | Pediatr Int2005，47，6： | 1 |
| 16 | Guidelines for diagnosis and management of cardiovascular sequelae in Kawasaki disease显示文摘 | Japaness Circulation Society Joint Research Group | 2005 | Pediatr Int2005，47，6： | 1 |
| 17 | Guidelines for diagnosis and management of cardiovascular sequelae in Kawasaki disease显示文摘 | Japaness Circulation Society Joint Research Group | 2005 | Pediatr Int2005，47，6： | 1 |
| 18 | Cost-effeetiveness of statins for primary cardiovascular prevention in chronic kidney disease显示文摘 | Erickson KF Japa S Owens DK | 2013 | J Am Coil Cardio12013，61，12： | 1 |
| 19 | Guidelines for diagnosis and management of cardiovascular sequelae in Kawasaki disease显示文摘 | Japaness Circulation Society Joint Research Group | 2005 | Pediatr Int2005，47，6： | 1 |
| 20 | Coupling between fluids and rock deformation in the continental crust:Preface显示文摘1.Introduction Fluids are essential and widespread components of the Earth crust.They regulate the main process of mass and energy transport,conditioning the geochemical and geophysical evolution of the crust(Bredehoeft and Norton.1990)and,consequently,its properties and mechanical behavior.The coupling between fluids,rock deformation,and heat are crucial engines for plate tectonics,playing a leading role in the rheology and evolution of the lithosphere(e.g.Jamtveit et al.,2000;Kennedy and van Soest,2007;Thompson,2010;Miller.2013;Yardley and Bodnar,2014:Hirauchi et al.,2016:Menzies et al.,2016;Plümper et al.,2017;Vizán et al.,2017). | Silvia Japas Sebastian Oriolo Vinod Samuel | 2019 | Geoscience Frontiers2019，10，6： | 0 |
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