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1053篇 您的检索式：作者名="Janssen P"

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	题名	作者	年代	出处	被引量
1	Telaprevir/boceprevir era: From bench to bed and back显示文摘Hepatitis C virus (HCV) infects approximately 200 million people worldwide. Interferon-based therapies have dominated over the past two decades. However, the overall response rates remain suboptimal. Thanks to the tremendous effort from both academia and industry, two serine protease inhibitors telaprevir and boceprevir for treating chronic hepatitis C have finally reached the clinic. Although these compounds are only approved for combination use with interferon and ribavirin in genotype 1 HCV infected chronic patients, the management of HCV patients however is now evolving incredibly. Here, we overviewed a series of landmark studies, regarding the clinical development of telaprevir and boceprevir. We discussed the mechanism-of-action of telaprevir/boceprevir and their potential application in HCV-positive liver transplantation patients. We further emphasized some emerging concerns with perspective of further development in this field.	Maikel P Peppelenbosch Harry LA Janssen Robert J de Knegt	2012	World Journal of Gastroenterology2012，18，43：	3
2	Overweight and obesity in Canadian adolescents an d their associations with dietary habits and physical activity patterns 显示文摘	JANSSEN I KATZMARZYK P T BOYCE W F	2004	J Add Health2004，35，5：	1
3	Giant optical transmis- sion of a subwavelength slit optimized using the magnetic field phase显示文摘	Janssen O T Urbach H P Hooft G W	2007	Physics Review Letter2007，99，04：	1
4	The influence of the refrigerant charge on the function of small refrigeration appliances 显示文摘	Kuijpers LJ M Janssen M J P	1988	ASHRAE Transactions1988，94，2：	1
5	Influence of the N-methyl -aspartate antagonist memantine on human motor cortex excilability 显示文摘	Schwenkreis P Witscher K Janssen F	1999	Neurosci Lett1999，270，3：	1
6	Supercritical carbon dioxide as a green solvent for processing polymer melts: processing aspects and applications 显示文摘	Nalawade S P Picchioni F Janssen L P B M	2006	Progress of Polymer Science2006，31，1：	1
7	Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitisB using HBsAg and HBV DNA levels 显示文摘	Rijckborst V Hansen BE Cakaloglu Y Ferenci P Tabak F Akdogan M Simon K Akarca US Flisiak R Verhey E Van Vuuren AJ Boucher CA ter Borg MJ Janssen HL	2010	Hepatology2010，52，2：	1
8	On the stability of reactive extrusion显示文摘	Janssen L P B M	1998	Polymer Engineering Science1998，38，12：	1
9	Measuring time-frequency information content using the Rényi entropies显示文摘	BARANIUK R G FLANDRIN P JANSSEN A J E M	2001	IEEE Trans on Information Theory2001，47，4：	1
10	Combi- ning full text and bibliometric information in mapping scientific disciplines 显示文摘	GLENISSON P GINZEL W JANSSENS F	2005	Information Processing & Management2005，41，6：	1
11	Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease显示文摘	Holvoet P Vanhaecke J Janssens S	1998	Circulation1998，98，15：	1
12	Structural insights into the central complement component C3 显示文摘	JANSSEN B J GROS P	2007	Mol Immunol2007，44，：	1
13	Thoraeoscopy : general overview and place in the diagnosis and management of pleural effusion显示文摘	Rodriquez - Panadero F Janssen JP Astoul P	2006	Eur Respir J2006，28，2：	1
14	Quantitative scoring of an interferon-gamma assay for differentiating active from latent tuberculosis显示文摘	Janssens JP Roux-Lombard P Perneger T	2007	Eur Respir J2007，30，4：	1
15	Sleep disordered breathing in the elderly显示文摘	Janssen J P Pautex S Hilleret H	2000	Aging2000，12，6：	1
16	Particle segregation in fluidized binary mixtures显示文摘	Hoffmann A C Janssen M L P B J Prins	1993	Chem Eng Sci1993，48，9：	1
17	Evaluation of the DNA finerpriting method AFLP as a new tool in Bacteral taxonomy显示文摘	Janssen P Coopman G Huys J	1996	Microbiology1996，142，：	1
18	Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection显示文摘	Tabeta K Georgel P Janssen E	2004	Proc Natl Acad Sci USA2004，101，10：	1
19	Methanogenic degradation of polysaccharides and the characterization of polysaccharolytic clostridia from anoxic rice field soil显示文摘	CHIN K J RAINET F A JANSSEN P H	1998	Systematic and Applied Microbiology1998，，21：	1
20	Diversity and structure of the methanogenic community in anoxic rice paddy soil microcosms as examined by cultivation and direct 16S rRNA gene sequence retrieval显示文摘	GroBkopf R Janssen P H Liesack W	1998	Applied and Environmental Microbiology1998，64，3：	1

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