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| 1 | Anti-HIV Ⅰ/Ⅱ Activity and Molecular Cloning of a Novel Mannose/Sialic Acidbinding Lectin from Rhizome of Polygonatum cyrtonema Hua显示文摘 | Jie AN Jin-Zhi LIU Chuan-Fang WU Jian LI Lei DAI Els Van DAMME Jan BALZARINI Erik De CLERCQ Fang CHEN Jin-Ku BAO | 2006 | Acta Biochimica et Biophysica Sinica2006，38，2： | 8 |
| 2 | 非核苷类逆转录酶抑制剂的研究XVⅢ:4-烯丙基和4-叠氮基取代的三嗪类化合物的合成及抗HIV活性(英文)显示文摘在已有工作基础上,基于分子对接设计合成了8个新的4-烯丙基取代和4-叠氮基取代的二芳基三嗪类衍生物。抗HIV-1活性的测试结果表明所有新化合物均具有抗HIV-1活性。其中化合物7c不仅抑制HIV-1野生株的复制(IC50=0.034μmol·L-1,SI=6475),且对Y181C和K103C双突变酶显示出较强的抑制活性,其IC50值为9.39μmol·L-1,高于奈韦拉平。 | 熊远珍 胡海荣 陈芬儿 Jan Balzarini Christophe Pannecouque Erik De Clercq | 2009 | 药学学报2009，44，2： | 2 |
| 3 | Nebrodeolysin, a novel hemolytic protein from mushroom Pleurotus nebrodensis with apoptosis-inducing and anti-HIV-1 effects显示文摘 | Hui Lv Yang Kong Qing Yao Bo Zhang Fang-wei Leng He-jiao Bian Jan Balzarini Els Van Damme Jin-ku Bao | 2008 | Phytomedicine2008，，2： | 1 |
| 4 | The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2′-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes显示文摘 | Johan Vande Voorde Sandra Liekens Christopher McGuigan Paola G.S. Murziani Magdalena Slusarczyk Jan Balzarini | 2011 | Biochemical Pharmacology2011，，5： | 1 |
| 5 | Microbicide drug candidates to prevent HIV infection 显示文摘 | Jan Balzarini Lut Van Damme | 2007 | Lancet2007，369，： | 1 |
| 6 | Synthesis of triterpenoid triazine derivatives from allobetulone and betulonic acid with biological activities显示文摘 | Thuc Dinh Ngoc Nico Moons Youngju Kim Wim De Borggraeve Anastassiya Mashentseva Graciela Andrei Robert Snoeck Jan Balzarini Wim Dehaen | 2014 | Bioorganic&Medicinal Chemistry2014，，22： | 1 |
| 7 | Structure–activity relationship of brominated 3-alkyl-5-methylene-2(5 H )-furanones and alkylmaleic anhydrides as inhibitors of Salmonella biofilm formation and quorum sensing regulated bioluminescence in Vibrio harveyi显示文摘 | Hans P. Steenackers Jeremy Levin Joost C. Janssens Ami De Weerdt Jan Balzarini Jos Vanderleyden Dirk E. De Vos Sigrid C. De Keersmaecker | 2010 | Bioorganic & Medicinal Chemistry2010，，14： | 1 |
| 8 | Synthesis,spectroscopic characterization and in vitro antitumor activities of some novel mononuclear Ru(Ⅱ) complexes显示文摘The synthesis and spectroscopic characterization of ruthenium complexes(R-l to R-8) of the type[Ru(A)_2(B)],(where A = 1,10-phenanthroline/2,2′-bipyridine and B = 3.4.5-tri-OCH_3DPC,4-CH_3-DPC,4-N-(CH_3)_2-DPC,4-NO_2-DPC arc described. These ligands form bidentate octahedral ruthenium complexes.The title complexes were subjected to in vitro cytotoxic activity measurements against the human cancer T-lymphocyte cell lines MTT assay.In vitro evaluation of these ruthenium complexes revealed cytotoxic activity from 0.24 to 1.4μg/mL against CEM,0.44 to 1.9μg/mL against Molt4/C8.0.28 to 1.5μg/mL against L1210,0.24 to 0.98μg/mL against HL60,and 0.25 to 1.2μg/mL against BEL7402,depending the nature of the compound. | Sreekanth Thota Mohammad Imran Manasa Udugula Rajeshwar Yerra Subhas S.Karki Jan Balzarini Erik De Clercq | 2012 | Chinese Chemical Letters2012，23，4： | 1 |
| 9 | Microbicide drug candidates to prevent HIV infection显示文摘 | Jan Balzarini Lut Van Damme | 2007 | Lancet2007，369，： | 1 |
| 10 | Man nose -Specific Plant Lectins from the Amaryllidaceae Familly Qualify as Efficient Microbicides for Prevention of Human Immunodeficiency Virus Infection显示文摘 | Jan Balzarini Sigrid Hatse Kurt Vermeire | 2004 | Antimicrobial Agents and Chemotherapy2004，48，10： | 1 |
| 11 | Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH ( OH )-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors显示文摘 | Shuang-Xi Gu Zhi-Ming Li Xiao-Dong Ma Shi-Qiong Yang Qiu-Qin He Fen-Er Chen Erik De Clercq Jan Balzarini Christophe Pannecouque | 2012 | European Journal of Medicinal Chemistry2012，，： | 1 |
| 12 | Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs显示文摘 | Shuang-Xi Gu Shi-Qiong Yang Qiu-Qin He Xiao-Dong Ma Fen-Er Chen Hui-Fang Dai Erik De Clercq Jan Balzarini Christophe Pannecouque | 2011 | Bioorganic & Medicinal Chemistry2011，，23： | 1 |
| 13 | Synthesis and structure–activity relationship of novel diarylpyrimidines with hydromethyl linker ( CH ( OH )-DAPYs) as HIV-1 NNRTIs显示文摘 | Shuang-Xi Gu Qiu-Qin He Shi-Qiong Yang Xiao-Dong Ma Fen-Er Chen Erik De Clercq Jan Balzarini Christophe Pannecouque | 2011 | Bioorganic & Medicinal Chemistry2011，，17： | 1 |
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