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| 1 | Ethnic difference of Helicobacter pylori gastritis: Korean and Japanese gastritis is characterized by male- and antrum-predominant acute foveolitis in comparison with American gastritis显示文摘AIM: To investigate the clinicopathological factors underlying the ethnic differences of Helicobacter pylori gastritis and cancer.METHODS: We analyzed clinicopathological parameters of gastric biopsies having H pylori infection that were randomly selected from different ethnic populations including 147 Americans, 149 Japanese, and 181 Koreans.RESULTS: Males were predominant in Japanese and Korean populations (77.9 and 67.4% respectively) in comparison with Americans (48.3%) (P<0.001). H pylori gastritis in Koreans and Japanese was characterized by the predominant antral involvement. In the antrum,neutrophilic infiltration into the proliferative zone of pit, i,e.acute foveolitis, was more frequent in Koreans (82%) than in Japanese (71%) (P<0.05) and Americans (61%) (P<0.001).Interstitial neutrophilic infiltration, intestinal metaplasia and atrophy were also frequent in Koreans and Japanese. In the body, the prevalence of acute foveolitis was not significantly different among the populations while chronic interstitial inflammation and lymphoid follicles were more pronounced in the body of Americans than in the body of others (P<0.01).CONCLUSION: The male-, and antrum-predominant Hpylori gastritis in Koreans and Japanese is compatible with the pattern of sex and topographical distribution of gastric cancer incidence. Our data suggest that persistent acute foveolitis at the proliferative zone is a crucial step in the gastric carcinogenesis. | Inchul Lee Hojung Lee Mijung Kim Manabu Fukumoto Shinji Sawada Shriram Jakate Victor E.Gould | 2005 | World Journal of Gastroenterology2005，11，1： | 5 |
| 2 | Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats显示文摘 | Ali Keshavarzian Ashkan Farhadi Christopher B. Forsyth Jayanthi Rangan Shriram Jakate Maliha Shaikh Ali Banan Jeremy Z. Fields | 2009 | Journal of Hepatology2009，，3： | 3 |
| 3 | Diagnostic yield of a novel jumbo biopsy “unroofing” technique for tissue acquisition of gastric submucosal masses显示文摘 | S. Komanduri L. Keefer S. Jakate | 2011 | Endoscopy2011，，10： | 2 |
| 4 | Multifocal granular cell tumor of the esophagus and proximal stomach with infiltrative pattern:a case report and review of the literature显示文摘 | David O jakate S | 1999 | Arch Pathol lab Med1999，123，： | 1 |
| 5 | Relationship of the multidrug resistance gene product(P-glycoprotein)in human colon carcinoma to local tumor aggressiveness and lymph node metastasis显示文摘 | Weinstein RS Jakate SM Dominguez JM | 1991 | Cancer Res1991，51，： | 1 |
| 6 | Crypt loss is a marker of clinical se- verity of acute gastrointestinal graft - versus - host disease 显示文摘 | Melson J Jakate S Fung H | 2007 | Am J Hematol2007，82，10： | 1 |
| 7 | Pharmacokinetic profile of dexloxiglumide 显示文摘 | PERSIANI S D' AMATO M JAKATE A | 2006 | Clin Pharmacokinet2006，45，12： | 1 |
| 8 | Multifocal granular cell tumor of the esophagus and proximal stomach with infiltrative pattern:a case report and review of the literature 显示文摘 | David O Jakate S | 1999 | Arch Pathol Lab Med1999，123，10： | 1 |
| 9 | Relationship of the expression of the multidrug resistance gene product (pglycoprotein)in human colon carinoma to local tumor aggressiveness and lympy node matastasis显示文摘 | RONALD S WEINSTEI M JAKATE M | 1991 | Cancer Research1991，51，： | 1 |
| 10 | A series of pharmacokinetic studies of ceftaroline fosamil in select populations: Normal subjects, healthy elderly subjects, and subjects with renal impairment or end-stage renal disease requiring hemodialysis显示文摘 | Todd Riccobene Abhijeet Jakate Doug Rank | 2014 | Journal of Clinical Pharmacology2014，，： | 1 |
| 11 | Relationship of the expression of the multidrug resistance gene product(P-glycoprotein)in human colon carcinoma to local tumor aggressiveness and lymph nodemetastasis显示文摘 | Weinstein RS Jakate SM Dominguez JM | | 0，，10： | 1 |
| 12 | Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis显示文摘 | Weinstein R S Jakate S M Dominguez J M | 1991 | Cancer Res1991，51，： | 1 |
| 13 | Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis 显示文摘 | Forsyth CB Farhadi A Jakate SM | 2009 | Alcohol2009，43，： | 1 |
| 14 | Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis显示文摘 | Weinstein RS Jakate SM Dominguez JM | 1991 | Cancer Res1991，51，： | 1 |
| 15 | Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress,gut leakiness,and liver injury in a rat model of alcoholic steatohepatitis显示文摘 | Forsyth CB Farhadi A Jakate SM | 2009 | Alcohol2009，43，2： | 1 |
| 16 | Gastric heterotopia presenting as a mass in jejunum 显示文摘 | Bhattacharya B Jakate S Saclafides TJ | 2003 | Arch Pathol Lab Med2003，127，4： | 1 |
| 17 | Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis 显示文摘 | Weinstein RS Jakate SM Dominguez JM | 1991 | Cancer Res1991，51，10： | 1 |
| 18 | Sleep deprivation worsens inflammation and delays recovery in a mouse model of colitis显示文摘 | Yueming Tang Fabian Preuss Fred W. Turek Shriram Jakate Ali Keshavarzian | 2009 | Sleep Medicine2009，，6： | 1 |
| 19 | Relationship of the expression of the muhidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis 显示文摘 | Weinstein RS Jakate SM Dominguez JM | 1991 | Cancer Res1991，51，10： | 1 |
| 20 | Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis显示文摘 | Forsyth CB Farhadi A Jakate SM | 2009 | Alcohol2009，43，2： | 1 |
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