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4篇 您的检索式:作者名="Jaime Gosalvez"
    题名 作者 年代 出处 被引量
1Bibliometrics: tracking research impact by selecting Lhe appropriate metrics显示文摘Ashok Agarwal Damayanthi Durairajanayagam Sindhuja Tatagari Sandro C Esteves Avi Harlev Ralf Henkel Shubhadeep Roychoudhury Sheryl Homa Nicolas Garrido Puchalt Ranjith Ramasamy Ahmad Majzoub Kim Dao Ly Eva Tvrda Mourad Assidi Kavindra Kesai Reecha Sharma Saleem Banihani Edmund Ko Muhammad Abu-Elmagd Jaime Gosalvez Asher Bashiri 2016Asian Journal of Andrology2016,18,2:10
2Specialized sperm function tests in varicocele ant Ihe future of andrology laboratory显示文摘Ahmad Majzoub Sandro C Esteves Jaime Gosalvez Ashok Agarwal 2016Asian Journal of Andrology2016,18,2:3
3The ability of sperm selection techniques to remove single- or double-strand DNA damage显示文摘为精子的准备的许多技术当前是可得到的,哪个通常采用的大多数是密度坡度 centrifugation (DGC ) 和游泳起来(啜) 。迄今为止,这些方法看起来在为帮助繁殖技术(艺术) 选择功能的精子有效,但是他们可以在精子 DNA 上有否定效果。在这研究,处理技术消除单个海滨的包含的精子和双海滨 DNA 损坏的这些精液的能力被在 157 件精液样品的二尾巴的彗星试金和精子染色质分散测试从寻求帮助繁殖治疗的病人估计。我们显示的结果啜并且 DGC 在消除包含双海滨 DNA 损坏和精子与的精子是同等地有效的高度损坏了(降级) DNA 由存在描绘了单个海滨并且双海滨 DNA 裂缝。然而, DGC 比在选择从单个海滨的 DNA 损坏是免费的精子啜是更有效的。未来研究应该描述 DNA 损坏的各种各样的类型的重要性并且检验处理在每个实验室过去常决定他们的能力消除 DNA 损坏并且因此,经由艺术阻止基因变化的潜在的传播的协议的精子。Maria Enciso Miriam Iglesias Isabel Galan Jonas Sarasa Antonio Gosalvez Jaime Gosalvez 2011Asian Journal of Andrology2011,13,5:2
4New approach to assess sperm DNA fragmentation dynamics: Fine-tuning mathematical models显示文摘Background: Sperm DNA fragmentation(sDF) has been proved to be an important parameter in order to predict in vitro the potential fertility of a semen sample. Colloid centrifugation could be a suitable technique to select those donkey sperm more resistant to DNA fragmentation after thawing. Previous studies have shown that to elucidate the latent damage of the DNA molecule, sDF should be assessed dynamically, where the rate of fragmentation between treatments indicates how resistant the DNA is to iatrogenic damage. The rate of fragmentation is calculated using the slope of a linear regression equation. However, it has not been studied if s DF dynamics fit this model. The objectives of this study were to evaluate the effect of different after-thawing centrifugation protocols on sperm DNA fragmentation and elucidate the most accurate mathematical model(linear regression, exponential or polynomial) for DNA fragmentation over time in frozen-thawed donkey semen.Results: After submitting post-thaw semen samples to no centrifugation(UDC), sperm washing(SW) or single layer centrifugation(SLC) protocols, sD F values after 6 h of incubation were significantly lower in SLC samples than in SW or UDC.Coefficient of determination(R^2) values were significantly higher for a second order polynomial model than for linear or exponential. The highest values for acceleration of fragmentation(aSDF) were obtained for SW, fol owed by SLC and UDC.Conclusion: SLC after thawing seems to preserve longer DNA longevity in comparison to UDC and SW. Moreover,the fine-tuning of models has shown that sDF dynamics in frozen-thawed donkey semen fit a second order polynomial model, which implies that fragmentation rate is not constant and fragmentation acceleration must be taken into account to elucidate hidden damage in the DNA molecule.Isabel Ortiz Jesus Dorado Jane Morrell Jaime Gosalvez Francisco Crespo Juan M.Jimenez Manuel Hidalgo 2017Journal of Animal Science and Biotechnology2017,8,3:0
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