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17篇 您的检索式:作者名="Jaewan"
    题名 作者 年代 出处 被引量
1Optimal design of multistory double shin facade显示文摘Jaewan Joe Wonj Choi un Kwak 2014Energy and Buildings2014,76,:1
2Light Extraction Enhancement from Nanoimprinted Photonic Crystal GaN-based Blue Lightemitting diodes 显示文摘J J Hyun Kyong Cho Jeong-Hyeon Choi Jaewan Choij 2006OPTICS EXPRESS(SI094-4087)2006,14,19:1
3Operation and control strategies for multi-storey double skin facades during the heating season显示文摘Wonjun Choi Jaewan Joe Younghoon Kwak 2012Energy and buildings2012,49,:1
4Load characteristics and operation strategies of building integrated with multi-storey double skin fa?ade 显示文摘Jaewan Joe Wonjun Choi Hansol Kwon 2013Energy and buildings2013,60,:1
5Effect of flow and tempera- ture distribution on the performance of a PEM fuel cell stack显示文摘Jaewan Park Xianguo Li 2006Journal of Power Sources2006,162,1:1
6Effect of flow and temperature distribution on the performance of a PEM fuel cell stack显示文摘Jaewan P Li Xianguo 2006Journal of Power Sources2006,162,1:1
7Comparison of wavefront aberration after cataract surgery with acrylic intraocular lens implantation显示文摘Jaewan Choi Tae-im Kim Hungwon Tchah 2005Journal of Cataract & Refractive Surgery2005,31,2:1
8Entanglement criceria via the uncertainty relations in su(2) and su(1,1) algebras:Detection of non-Gaussian entangled states显示文摘HYUNCHUL N JAEWAN K 0,,:1
9Effect of flow and temperaturedistribution on theperformance of a PEM fuel cell stack显示文摘Jaewan Park Xianguo Li 2006Journal of Power Sources2006,162,1:1
10A flow channel design procedure for PEM fuel cells with effective water removal显示文摘Xianguo Li Imran Sabir Jaewan Park 2007Journal of Power Sources2007,163,:1
11A New AdaptiveComponent-Substitution-Based Satellite Image Fusion byUsing Partial Replacement 显示文摘JAEWAN C KIYUN Y YONGIL K 2011IEEE Transactions onGeoscience and Remote Sensing2011,49,1:1
12A flow channel design procedure for PEM fuel cells with effective water removal显示文摘Li Xianguo Sabir Imran Park Jaewan 2007Journal of Power Sources2007,163,2:1
13Optimal design of multi-story double shin fa ade显示文摘Jaewan Joe Wonj Choi un Kwak 2014Energy and Buildings2014,,76:1
14Identification of two HIV inhibitors that also inhibit human RNaseH2显示文摘Junghwan Kim Jaewan Yoon MoonKyeong Ju Yunmi Lee Tae-Hee Kim Junwon Kim Peter Sommer Zaesung No Jonathan Cechetto Sung-Jun Han 2013Molecules and Cells2013,,3:1
15All-in-one glycol chitosan nanoparticles for co-delivery of doxorubicin and anti-PD-L1 peptide in cancer immunotherapy显示文摘Synergistic immunotherapy of immune checkpoint blockade (ICB) and immunogenic cell death (ICD) has shown remarkable therapeutic efficacy in various cancers. However, patients show low response rates and undesirable outcomes to these combination therapies owing to the recycling mechanism of programmed death-ligand 1 (PD-L1) and the systemic toxicity of ICD-inducing chemotherapeutic drugs. Herein, we propose all-in-one glycol chitosan nanoparticles (CNPs) that can deliver anti-PD-L1 peptide (PP) and doxorubicin (DOX) to targeted tumor tissues for a safe and more effective synergistic immunotherapy. The PP-CNPs, which are prepared by conjugating ᴅ-form PP (NYSKPTDRQYHF) to CNPs, form stable nanoparticles that promote multivalent binding with PD-L1 proteins on the targeted tumor cell surface, resulting in effective lysosomal PD-L1 degradation in contrast with anti-PD-L1 antibody, which induces recycling of endocytosed PD-L1. Consequently, PP-CNPs prevent subcellular PD-L1 recycling and eventually destruct immune escape mechanism in CT26 colon tumor-bearing mice. Moreover, the ICD inducer, DOX is loaded into PP-CNPs (DOX-PP-CNPs) for synergistic ICD and ICB therapy, inducing a large number of damage-associated molecular patterns (DAMPs) in targeted tumor tissues with minimal toxicity in normal tissues. When the DOX-PP-CNPs are intravenously injected into CT26 colon tumor-bearing mice, PP and DOX are efficiently delivered to the tumor tissues via nanoparticle-derived passive and active targeting, which eventually induce both lysosomal PD-L1 degradation and substantial ICD, resulting in a high rate of complete tumor regression (CR: 60%) by a strong antitumor immune response. Collectively, this study demonstrates the superior efficacy of synergistic immunotherapy using all-in-one nanoparticles to deliver PP and DOX to targeted tumor tissues.Sukyung Song Man Kyu Shim Suah Yang Jaewan Lee Wan Su Yun Hanhee Cho Yujeong Moon Jin Young Min Eun Hee Han Hong Yeol Yoon Kwangmeyung Kim 2023Bioactive Materials2023,,10:0
16多相CeO2催化剂上氧化吲哚与醛的选择性C3烯基化反应显示文摘本文报道了将市售CeO2作为一种高活性和可重复使用的催化剂用于无溶剂条件下氧化吲哚与醛的C3选择性烷基化反应.这种催化方法一般适用于不同的芳香族和脂肪族醛,得到3-烷基二烯-辛醇,产率高(87%–99%),立体选择性高(79%–93%为E-异构体).这是从氧化吲哚与各种脂肪族醛催化合成3-烯基氧化吲哚的首例.采用原位红外光谱研究了CeO2上Lewis酸位点与苯甲醛之间的Lewis酸-碱相互作用.不同粒径CeO2催化剂的构效关系研究表明,无缺陷CeO2表面是该反应的活性中心.MdNurnobi Rashed Abeda Sultana Touchy Chandan Chaudhari Jaewan Jeon S.M.A.Hakim Siddiki Takashi Toyao Ken-ichi Shimizu 2020Chinese Journal of Catalysis2020,41,6:0
17A structure translation model for crystal compounds显示文摘High-throughput virtual screening for crystals aims to discover new materials by evaluating the property of every virtual candidate in the database exhaustively.During this process,the major computational bottleneck is the costly structural relaxation of each hypothetical material on the large-scale dataset using density functional theory(DFT)calculations.Here,we present a generative domain translation framework that maps the unrelaxed structural domains to the relaxed domains,enabling data-driven structural translations.The model predicts the materials formation energy with a small mean absolute error without DFT relaxations,and furthermore can produce the atomic coordinates consistent with the DFT relaxed structures.The utility of the proposed concept is not restricted to the structural domains,and we expect that it can be extended to translate the domain of easy-to-compute properties into the domain of more difficult properties.Sungwon Kim Juhwan Noh Taewon Jin Jaewan Lee Yousung Jung 2023npj Computational Materials2023,,1:0
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