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| 1 | Exchange flux of total gaseous mercury between air and natural water surfaces in summer season显示文摘The exchanges of mercury between surface and air are of significance in the biogeochemical cycling of Hg in the environment, but there are still few reliable data on air/surface exchange in aquatic systems. Field measurement campaigns over seawater surface at Kristineberg Marine Research Station (KMRS) and over Hovg?rds?n River surface at Knobesholm in southwestern Sweden were conducted to measure mercury flux using a dynamic flux chamber technique coupled with automatic mercury vapor-phase analyzers. Both sites show net emissions during summer time. Mercury fluxes measured over both river and seawater surfaces exhibit a consistently diurnal pattern with maximum fluxes during the daytime period and minimum fluxes during the nighttime period. At freshwater site, mercury flux is strongly correlated with the intensity of net solar radiation, and negatively correlated with relative humidity. A typical exponential relationship between mercury flux and water temperature was observed at freshwater measurement site. At seawater site, a strong correlation between mercury flux and intensity of solar radiation was obtained. The driving force of mercury emission from water surface to air is the super-saturation of dissolved gaseous mercury in aqueous phase. | 冯新斌 Jonas Sommar Katarina Grdfeldt OliverLindqvist | 2002 | Science China Earth Sciences2002，45，3： | 10 |
| 2 | 针对患者利益的机器学习和人工智能研究:在透明性、可重复性、伦理和有效性等方面的20个关键问题显示文摘机器学习(ML)、人工智能(AI)和其他现代统计方法正为利用先前尚未开发且极速增长的数据资源提供新的机会,以期让患者获益。尽管目前正在进行许多有前景的研究,特别是在图像方面,但就文献整体而言还缺乏透明度、对可重复性清晰的阐述、对潜在伦理问题的探究,以及对有效性的明确验证。这些问题的存在有许多原因,其中最重要的一点(为此我们提供了初步解决方案)就是当前缺乏针对ML和AI的最佳实践指南。我们认为从事研究的跨学科团队和应用ML/AI影响健康的项目,将因解决有关透明度、可重复性、伦理和有效性(TREE)的一系列问题而受益。这里提出的20个关键问题为研究团队提供了一个研究设计、实施和报告框架;帮助编辑和同行评审专家评估文献的贡献;让患者、临床医生和政策制定者评估新发现可能会给患者带来的获益。 | Sebastian Vollmer Bilal A Mateen Gergo Bohner Franz J Kirdly Rayid Ghani Pall Jonsson Sarah Cumbers Adrian Jonas Katherine S L McAllister Puja Myles David Granger Mark Birse Richard Branson Karel G M Moons Gary S Collins John P A Chris Holmes Harry Hemingwayp 李峰(译) 徐磊(校) 赵邑(校) | 2020 | 英国医学杂志中文版2020，23，9： | 5 |
| 3 | Mapping aboveground biomass and its prediction uncertainty using LiDAR and field data, accounting for tree-level allometric and LiDAR model errors显示文摘Background: The increasing availability of remotely sensed data has recently challenged the traditional way of performing forest inventories, and induced an interest in model-based inference. Like traditional design-based inference, model-based inference allows for regional estimates of totals and means, but in addition for wall-to-wall mapping of forest characteristics. Recently Light Detection and Ranging(LiDAR)-based maps of forest attributes have been developed in many countries and been well received by users due to their accurate spatial representation of forest resources. However, the correspondence between such mapping and model-based inference is seldom appreciated. In this study we applied hierarchical model-based inference to produce aboveground biomass maps as well as maps of the corresponding prediction uncertainties with the same spatial resolution. Further, an estimator of mean biomass at regional level, and its uncertainty, was developed to demonstrate how mapping and regional level assessment can be combined within the framework of model-based inference.Results: Through a new version of hierarchical model-based estimation, allowing models to be nonlinear, we accounted for uncertainties in both the individual tree-level biomass models and the models linking plot level biomass predictions with LiDAR metrics. In a 5005 km2 large study area in south-central Sweden the predicted aboveground biomass at the level of 18 m×18 m map units was found to range between 9 and 447 Mg·ha^-1. The corresponding root mean square errors ranged between 10 and 162 Mg·ha^-1. For the entire study region, the mean aboveground biomass was 55 Mg·ha^-1 and the corresponding relative root mean square error 8%. At this level 75%of the mean square error was due to the uncertainty associated with tree-level models.Conclusions: Through the proposed method it is possible to link mapping and estimation within the framework of model-based inference. Uncertainties in both tree-level biomass models and models linking plot level biomass with LiDAR data are accounted for, both for the uncertainty maps and the overall estimates. The development of hierarchical model-based inference to handle nonlinear models was an important prerequisite for the study. | Svetlana Saarela AndréWästlund Emma Holmström Alex Appiah Mensah Sören Holm Mats Nilsson Jonas Fridman Göran Ståhl | 2020 | Forest Ecosystems2020，7，3： | 3 |
| 4 | Confocal laser endomicroscopy for the differential diagnosis of ulcerative colitis and Crohn’s disease: a pilot study显示文摘 | Gian Tontini Jonas Mudter Michael Vieth Raja Atreya Claudia Günther Yurdagül Zopf Dane Wildner Ralf Kiesslich Maurizio Vecchi Markus Neurath Helmut Neumann | 2014 | Endoscopy2014，，： | 2 |
| 5 | Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome:A multicenter retrospective study显示文摘BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bowel syndrome(IBS).AIM To assess the association of HTR3 polymorphisms with depressive,anxiety,and somatization symptoms in individuals with IBS.METHODS In this retrospective study,623 participants with IBS were recruited from five specialty centers in Germany,Sweden,the United States,the United Kingdom,and Ireland.Depressive,anxiety,and somatization symptoms and sociodemographic characteristics were collected.Four functional SNPs—HTR3A c.-42C>T,HTR3B c.386A>C,HTR3C c.489C>A,and HTR3E c.*76G>A—were genotyped and analyzed using the dominant and recessive models.We also performed separate analyses for sex and IBS subtypes.SNP scores were calculated as the number of minor alleles of the SNPs above.The impact of HTR3C c.489C>A was tested by radioligand-binding and calcium influx assays.RESULTS Depressive and anxiety symptoms significantly worsened with increasing numbers of minor HTR3C c.489C>A alleles in the dominant model(F_(depressive)=7.475,P_(depressive)=0.006;F_(anxiety)=6.535,P_(anxiety)=0.011).A higher SNP score(range 0-6)was linked to a worsened depressive symptoms score(F=7.710,P-linear trend=0.006)in IBS.The potential relevance of the HTR3C SNP was corroborated,showing changes in the expression level of 5-HT3AC variant receptors.CONCLUSION We have provided the first evidence that HTR3C c.489C>A is involved in depressive and anxiety symptoms in individuals with IBS.The SNP score indicated that an increasing number of minor alleles is linked to the worsening of depressive symptoms in IBS. | Sabrina Berens Yuanjun Dong Nikola Fritz Jutta Walstab Mauro D'Amato Tenghao Zheng Verena Wahl Felix Boekstegers Justo Lorenzo Bermejo Cristina Martinez Stefanie Schmitteckert Egbert Clevers Felicitas Engel Annika Gauss Wolfgang Herzog Robin Spiller Miriam Goebel-Stengel Hubert Mönnikes Viola Andresen Frieling Thomas Jutta Keller Christian Pehl Christoph Stein-Thöringer Gerard Clarke Timothy G Dinan Eamonn M Quigley Gregory Sayuk Magnus Simrén Jonas Tesarz Gudrun Rappold Lukas van Oudenhove Rainer Schaefert Beate Niesler | 2022 | World Journal of Gastroenterology2022，28，21： | 2 |
| 6 | Variant selection of primary, secondary and tertiary twins in a deformed Mg alloy显示文摘 | Sijia Mu John J. Jonas Günter Gottstein | 2012 | Acta Materialia2012，，5： | 2 |
| 7 | Treatment of keratoconus by toric foldable intraocular lenses 显示文摘 | Sauder G Jonas JB | 2003 | Eur J Ophthalmol2003，13，6： | 1 |
| 8 | Comprehensive approach to modeling and simulation of photovohaic arrays 显示文摘 | MARCELO G V JONAS R G ERNESTO R F | 2009 | IEEE Transactions on Power Electronics2009，24，5： | 1 |
| 9 | Ahemative RNA processing in caleitonin gene expression generates mRNAs encoding different polypeptide products显示文摘 | Amara S G Jonas V Rosenfeld M G | 1982 | Nature1982，298，15： | 1 |
| 10 | Accumulation of glycine detaine in chloroplast provide sosmotic adjustment during saltstress 显示文摘 | Robinso S P Jonas G P | 1986 | Plant Physiol1986，13，8： | 1 |
| 11 | Comprehensive approach to modeling and simulation of photovoltaic arrays显示文摘 | Marcelo G V Jonas R G Ernesto R F | 2009 | IEEE transactions on power electronics2009，24，5： | 1 |
| 12 | Technical applications for conductive polymers显示文摘 | Jonas F Heywang G | | 0，，8： | 1 |
| 13 | Poly ,(alkylenedioxythiophene) sNew,Very Stable Conducting Polymers显示文摘 | Heywang G Jonas F | | 0，，02： | 1 |
| 14 | Optimizing cerebral oxygenation during cardiac surgery: a review of experimental and clinical investigations with near infrared spectrophotometry显示文摘 | Nollert G Jonas RA Reichart B | 2000 | Thorac Cardiovasc Surg2000，48，4： | 1 |
| 15 | Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products 显示文摘 | Amara S G Jonas V Rosenfeld M G | 1982 | Nature1982，298，5871： | 1 |
| 16 | The onset of flow localization in tensile samples containing geometric and metallurgical defects显示文摘 | Jonas J J Christodoulou N G'Sell C | 1978 | Scripta Metallurgica1978，12，： | 1 |
| 17 | Systematic review:comparative effectiveness and harms of disease-modifying medications for rheumatoid arthritis显示文摘 | DONAHUE KE GARTLEHNER G JONAS DE | 2008 | Ann Intern Med2008，148，2： | 1 |
| 18 | Alternative RNA processing in calcitonin gene expression gene rates mRNAs encoding different polypeptide products显示文摘 | AMARA S G JONAS V ROSENFELD M G | 1982 | Nature1982，298，： | 1 |
| 19 | Sensi- tivity of a modified version of the ARCHITECT Anti HCV test in detecting samples with immunoblot confirmed, low 1 evel antibody to hepatitis C virus显示文摘 | ECHEVARRIA JM AVELLON A JONAS G | 2006 | J Clin Virol2006，35，4： | 1 |
| 20 | Sensitivity of a modified version of the ARCHITECT Anti-HCV test in detecting samples with immunoblot-confirmed, low-level antibody to hepatitis C virus显示文摘 | Echevarria J M Avell6n A Jonas G | 2006 | J Clin Virol2006，35，4： | 1 |
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