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306篇 您的检索式:作者名="JAMIESON R"
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1Methylation of TIMP3 in esophageal squamous cell carcinoma显示文摘AIM: To measure the frequency of DNA methylation of the tissue inhibitor of metalloproteinase 3 (TIMP3) promoter and relate this to any change of gene expression in esophageal squamous cell carcinoma in patients from a region of high incidence in China.METHODS: Cancer cell lines were treated with or without the demethylating reagent 5-aza-2’-deoxycytidine. Methylation of the TIMP3 promoter was assessed in three regions by melt curve analysis and its expression was assessed by real-time RT-PCR. Tumors and proximal resection margins were obtained from 64 patients with esophageal squamous cell carcinoma from a region of high incidence in China. Methylation was assessed by melt curve analysis and expression by immunohistochemistry.RESULTS: Methylation in one of the three promoter regions assessed correlated with gene silencing in esophageal cell lines. A degree of methylation of TIMP3 was found in only four esophageal squamous cell carcinomas, and partial loss of TIMP3 protein expression in just one.CONCLUSION: Methylation and loss of expression of TIMP3 occurs infrequently in esophageal squamous cell carcinoma in a region of high incidence in China.Eric Smith Neville J De Young Zi-Qiang Tian Maria Caruso Andrew R Ruszkiewicz Jun-Feng Liu Glyn G Jamieson Paul A Drew 2008World Journal of Gastroenterology2008,14,2:2
2Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda显示文摘Gedeon A K Colley A Jamieson R 1999Nat Genet1999,22,4:1
3Grain number, wheat yield,and bottling beer:An analysis显示文摘Sinclair T R Jamieson P D 2006Field Crops Research2006,98,:1
43D Flow and Sediment Dynamics in a Laboratory Channel Bend with and without Stream Barbs 显示文摘JAMIESON E C RENNIE C D TOWNSEND R D 2013Journal of Hy- draulic Engineering2013,139,2:1
5Performance of bioprostheses and mechanical prostheses in age group 61-70 years显示文摘Prasongsukarn K Jamieson W R Lichtenstein S V 2005J Heart Valve Dis2005,14,50:1
6Biological applications of quantum dots 显示文摘Jamieson T Bakhshi R Pctrova D ct al 2007Biomaterials2007,28,:1
7The use of aer- ation to enhance ammonia nitrogen removal in constructed wetlands 显示文摘Jamieson T S Stratton G W Gordon R 2003Canadian Biosystems Engineering2003,,45:1
8Direct slicing of CAD models for rapid prototyping 显示文摘Jamieson R Hacker H 1995Rapid Prototyping Journal1995,1,2:1
9Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda显示文摘Gedeon AK Colley A Jamieson R 1999Nat Genet1999,22,4:1
10Interactions between oestradiol and glucocorticoid regulatoryeffects on liver-specific glucocorticoid-inducible genes : possibleevidence for a role of hepatic 1 l(3-hydroxysteroid dehydrogenasetype 1 显示文摘JAMIESON P M NYIRENDA M J WALKER B R 1999J Endocrinol1999,160,1:1
11Mechanical and bioprosthetic Aortic Valve replacement显示文摘W R Eric Jamieson 1997Cardiac surgery in the adult1997,859,:1
12The potential role of geosynthetic clay liners in mine water treatment systems显示文摘Lange K Rowe R K Jamieson H 2010Geotextiles and Geomembranes2010,28,2:1
13What prosthesis should be used at valve re replacement after structural valve deterioration of a bioprosthesis显示文摘Lau L Jamieson W R Hughes C 2006Ann Thorac Surg2006,82,6:1
14Five-year follow-up of a randomized clinical trial of laparoscopic total versus anterior 180 degrees fundoplication 显示文摘Ludemann R Watson DI Jamieson GG 2005Br J Surg2005,92,2:1
15Modeling grain nitrogen auccmulation composition to protein composition to understand the sink/soure regulations of nitrogen remobilization for wheat显示文摘Martre P Porter J R Jamieson P D 2003Plant Physiol2003,133,:1
16Isolation and primary structure of two peptides with cardioacceleratory and hyperglycemic activity from the corpora cardiaca of Periplaneta americana 显示文摘SCARBOROUGH R M JAMIESON G C KALISH F 1984Proc Natl Acad Sci U S A1984,81,17:1
17Domain disruption and mutation of the bZIP transcription factor, MAF, associated with cataract, ocular anterior segment dysgenesis and coloboma显示文摘Jamieson RV Perveen R Kerr B 2002Hum Mot Genet2002,11,:1
18Metamorphism of an early Palaeozoic continental margin, western Baie Verte Peninsula, Newfoundland显示文摘Jamieson R A 1990Journal of Metamorphic Geology1990,8,3:1
19Direct slicing of CAD models for rapid prototyping显示文摘JAMIESON R HACKER H 1995Rapid Prototyping Journal1995,1,2:1
20Guideline for oral health care for long-stay patients and residents 显示文摘Fiske J Griffiths J Jamieson R 2000Gerodontology2000,17,1:1
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