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您的检索式：作者名="Isabelle Germon"
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| 1 | Rck of Salmonella enterica, subspecies enterica serovar Enteritidis, mediates Zipper-like internalization显示文摘沙门氏菌能通过它的类型 III 分泌物系统(T3SS-1 ) 入侵非吞噬细胞的房间,它导致一个扳机入口过程。这研究显示出那沙门氏菌 enterica,亚种 enterica serovar Enteritidis 能也经由 Rck 外部膜蛋白质入侵房间。Rck 必要、足够启用非侵略的 E。coli 和 Rck 涂的祷告遵守并且入侵不同房间。与不同 Rck 肽涂的乳胶祷告的成为主观分析证明包含氨基酸 140-150 的肽支持了粘附,而在 150 和 159 之间的氨基酸调制了侵略。主导否定的衍生物的表示和特定的禁止者的使用在激活 Arp2/3 建筑群触发充满肌动朊的累积的形成表明了小 GTPases Rac1 和 Cdc42 的关键角色,导致 Rck 依赖的成为主观。最后,扫描并且有 Rck 涂的祷告和 E 的传播电子显微镜学。表示 Rck 的 coli 揭示了形成了像拉链的结构的象 microvillus 一样延期,吞没支持者祷告和细菌。总的来说,我们的结果提供新卓见进沙门氏菌 T3SS 独立的侵略机制并且强烈建议 Rck 导致像拉链的入口机制。因而,沙门氏菌似乎是发现能导致拉链和扳机机制入侵宿主细胞的第一个细菌。 | Manon Rosselin Isabelle Virlogeux-Payant Christian Roy Elisabeth Bottreau Pierre-Yves Sizaret Lily Mijouin Pierre Germon Emmanuelle Caron Philippe Velge Agnes Wiedemann | 2010 | Cell Research2010，20，6： | 4 |
| 2 | Genetic identification and reiterated captures suggest that the Astyanax mexicanus El Pachón cavefish population is closed and declining显示文摘The sizes of Astyanax mexicanus blind cavefish populations of North-East Mexico are demographic parameters of great importance for investigating a variety of ecological,evolutionary,and conservation issues.However,few estimates have been obtained.For these mobile animals living in an environment difficult to explore as a whole,methods based on capture-mark-recapture are appropriate,but their feasibility and interpretation of results depend on several assumptions that must be carefully examined.Here,we provide evidence that minimally invasive genetic identification from captures at different time intervals(three days and three years)can give insights into cavefish population size dynamics as well as other important demographic parameters of interest.We also provide tools to calibrate sampling and genotyping efforts necessary to reach a given level of precision.Our results suggest that the El Pachón cave population is currently very small,of an order of magnitude of a few hundreds of individuals,and is distributed in a relatively isolated area.The probable decline in population size in the El Pachón cave since the last census in 1971 raises serious conservation issues. | Laurent Legendre Julie Rode Isabelle Germon Marie Pavie Carla Quiviger Maxime Policarpo Julien Leclercq Stéphane Père Julien Fumey Carole Hyacinthe Patricia Ornelas-García Luis Espinasa Sylvie Rétaux Didier Casane | 2023 | Zoological Research2023，44，4： | 0 |
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