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| 1 | Factors related to quality of life in patients with cirrhosis and ascites: Relevance of serum sodium concentration and leg edema显示文摘 | Elsa Solà Hugh Watson Isabel Graupera Fanny Turón Rogelio Barreto Ezequiel Rodríguez Marco Pavesi Vicente Arroyo Mónica Guevara Pere Ginès | 2012 | Journal of Hepatology2012，，6： | 3 |
| 2 | Assessing the estrogenic potency in a Portuguese wastewater treatment plant using an integrated approach显示文摘The estrogenic potency of a wastewater treatment plant(WWTP) was evaluated using chemical and biological analyses,which showed that after the station treatment processes some of the selected endocrine disruptor compounds(EDCs) were still present in the treated effuent(e.g.,bisphenol A,alkylphenols,estrone) .Thus,the most common endocrine EDCs were identified and quantified and the overall estrogenicity of the treated effuent assessed by integrating the results.Male goldfish(Carassius auratus) were used as biological indicators in a 28-day experiment.Vitellogenin(Vtg) ,gonadosomatic and hepatosomatic indices,steroids(17β-estradiol and 11-ketotestosterone) and histopathology were biomarkers used in fish to evaluate WWTP treated effuent estrogenicity,in combination with instrumental analyses.The results showed a significant increase(P<0.01) in plasma and liver Vtg,which were significantly correlated(r=0.66;P<0.01) .The gonadosmatic index was significantly(P<0.01) reduced in exposed fish.The steroid analyses revealed significant elevations in 17β-estradiol and depressed 11-ketotestosterone concentrations.The histological examinations show changes in exposed fish gonads,such as regressed testes and in some cases(43%to 75%) the development of ovo-testis in fish exposed to 50% and 100% treated effuent. | Mário S.Diniz Rita Maurício Mira Petrovic Maria J.López De Alda Leonor Amaral Isabel Peres Damiá Barceló Fernando Santana | 2010 | Journal of Environmental Sciences2010，22，10： | 2 |
| 3 | Severe acute kidney injury associated with non-steroidal anti-inflammatory drugs in cirrhosis: A case-control study显示文摘 | Chiara Elia Isabel Graupera Rogelio Barreto Elsa Solà Rebeca Moreira Patricia Huelin Xavier Ariza Cristina Solé Elisa Pose Anna Baiges Núria Fabrellas Esteban Poch Javier Fernández Vicente Arroyo Pere Ginès | 2015 | Journal of Hepatology2015，，3： | 1 |
| 4 | A modified acute kidney injury classification for diagnosis and risk stratification of impairment of kidney function in cirrhosis显示文摘 | Claudia Fagundes Rogelio Barreto Mónica Guevara Elisabet Garcia Elsa Solà Ezequiel Rodríguez Isabel Graupera Xavier Ariza Gustavo Pereira Ignacio Alfaro Andrés Cárdenas Javier Fernández Esteban Poch Pere Ginès | 2013 | Journal of Hepatology2013，，： | 1 |
| 5 | A modified acute kidney injury classification for diagnosis and risk stratification of impairment of kidney function in cirrhosis显示文摘 | Claudia Fagundes Rogelio Barreto Mónica Guevara Elisabet Garcia Elsa Solà Ezequiel Rodríguez Isabel Graupera Xavier Ariza Gustavo Pereira Ignacio Alfaro Andrés Cárdenas Javier Fernández Esteban Poch Pere Ginès | 2013 | Journal of Hepatology2013，，： | 1 |
| 6 | Massive mesh hole repair minimizing user intervention显示文摘 | Pere Brunet Antoni Chica Isabel Navazo àlvar Vinacua | 2009 | Computing2009，，2： | 1 |
| 7 | A multi-integrated approach on toxicity effects of engineered TiO2 nanoparticles显示文摘设计 nanoparticles 的新性质在有机体和生态系统上在安全,命运,行为和这些粒子的生物学的效果上为新知识驾驶需要。钛二氧化物 nanoparticles 为大量应用广泛地被使用了,例如,自我清洗的表面涂层,太阳能电池,水处理代理人,热门 sunscreens。在这种情形以内,增加的环境暴露能被期望,但是 nanoparticles 的 ecotoxicological 评估上的数据仍然是少见的。这个工作的主要目的是在几个有机体的 TiO 2 nanoparticles 的效果的评估,盖住不同营养的层次,用一组水的试金。也用组织学的脊椎动物模型有机体纸巾和 ultrastructural 观察和压力酶活动是的鱼学习了。TiO 2 nanoparticles (Aeroxide?P25 ) ,锐钛矿(65%) 的二篇阶段作文和有一个平均粒子的金红石(35%) 缩放 27.6 | Ana PICADO Susana M. PAIXAO Liliana MOITA Luis SILVA Mario S. DINIZ Joana LOURENCO Isabel PERES Luisa CASTRO Jose Brito CORREIA Joana PEREIRA Isabel FERREIRA Antonio Pedro Alves MATOS Pedro BARQUINHA Elsa MENDONCA | 2015 | Frontiers of Environmental Science & Engineering2015，9，5： | 1 |
| 8 | Chromatin condensation but not DNA integrity of pig sperm is greater in the sperm-rich fraction显示文摘Background Protamination and condensation of sperm chromatin as well as DNA integrity play an essential role during fertilization and embryo development.In some mammals,like pigs,ejaculates are emitted in three separate fractions:pre-sperm,sperm-rich(SRF)and post sperm-rich(PSRF).These fractions are known to vary in volume,sperm concentration and quality,as well as in the origin and composition of seminal plasma(SP),with differences being also observed within the SRF one.Yet,whether disparities in the DNA integrity and chromatin condensation and pro-tamination of their sperm exist has not been interrogated.Results This study determined chromatin protamination(Chromomycin A3 test,CMA_(3)),condensation(Dibromobi-mane test,DBB),and DNA integrity(Comet assay)in the pig sperm contained in the first 10 m L of the SRF(SRF-P1),the remaining portion of the sperm-rich fraction(SRF-P2),and the post sperm-rich fraction(PSRF).While chromatin protamination was found to be similar between the different ejaculate fractions(P>0.05),chromatin condensation was seen to be greater in SRF-P1 and SRF-P2 than in the PSRF(P=0.018 and P=0.004,respectively).Regarding DNA integrity,no differences between fractions were observed(P>0.05).As the SRF-P1 has the highest sperm concentra-tion and ejaculate fractions are known to differ in antioxidant composition,the oxidative stress index(OSi)in SP,calcu-lated as total oxidant activity divided by total antioxidant capacity,was tested and confirmed to be higher in the SRF-P1 than in SRF-P2 and PSRF(0.42±0.06 vs.0.23±0.09 and 0.08±0.00,respectively;P<0.01);this index,in addition,was observed to be correlated to the sperm concentration of each fraction(Rs=0.973;P<0.001).Conclusion While sperm DNA integrity was not found to differ between ejaculate fractions,SRF-P1 and SRF-P2 were observed to exhibit greater chromatin condensation than the PSRF.This could be related to the OSi of each fraction. | Estel Viñolas-Vergés Jordi Ribas-Maynou Isabel Barranco Camila Peres Rubio Sergi Bonet Jordi Roca Marc Yeste | 2024 | Journal of Animal Science and Biotechnology2024，15，1： | 0 |
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