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| 1 | Food groups, diet quality and colorectal cancer risk in the Basque Country显示文摘BACKGROUND The results obtained to date concerning food groups,diet quality and colorectal cancer(CRC)risk vary according to criteria used and the study populations.AIM To study the relationships between food groups,diet quality and CRC risk,in an adult population of the Basque Country(North of Spain).METHODS This observational study included 308 patients diagnosed with CRC and 308 ageand sex-matched subjects as controls.During recruitment,dietary,anthropometric,lifestyle,socioeconomic,demographic and health status information was collected.Adherence to the dietary recommendations was evaluated utilizing the Healthy Eating Index for the Spanish Diet and the MedDietScore.Conditional logistic regressions were used to evaluate the associations of food group intakes,diet quality scores,categorized in tertiles,with CRC risk.RESULTS The adjusted models for potential confounding factors showed a direct association between milk and dairy products consumption,in particular high-fat cheeses[odds ratio(OR)third tertile vs first tertile=1.87,95%confidence intervals(CI):1.11-3.16],and CRC risk.While the consumption of fiber-containing foods,especially whole grains(OR third tertile vs first tertile=0.62,95%CI:0.39-0.98),and fatty fish(OR third tertile vs first tertile=0.53,95%CI:0.27-0.99)was associated with a lower risk for CRC.Moreover,higher MD adherence was associated with a reduced CRC risk in adjusted models(OR third tertile vs first tertile=0.40,95%CI:0.20-0.80).CONCLUSION Direct associations were found for high-fat cheese,whereas an inverse relation was reported for fiber-containing foods and fatty fish,as well as adherence to a Mediterranean dietary pattern. | Iker Alegria-Lertxundi Carmelo Aguirre Luis Bujanda Francisco J Fernandez Francisco Polo JoseMªOrdovas MªCarmen Etxezarraga Inaki Zabalza Mikel Larzabal Isabel Portillo Marian M de Pancorbo Koldo Garcia-Etxebarria Ana MªRocandio Marta Arroyo-Izaga | 2020 | World Journal of Gastroenterology2020，26，28： | 3 |
| 2 | A mutation in the drug transporter gene ABCC2 associated with impaired methotrexate elimination显示文摘 | Jean-Sébastien Hulot Eric Villard Ange Maguy Véronique Morel Lluis Mir Isabelle Tostivint Demiana William-Faltaos Christine Fernandez Stéphane Hatem Gilbert Deray Michel Komajda Véronique Leblond Philippe Lechat | 2005 | Pharmacogenetics and Genomics2005，，5： | 1 |
| 3 | Detection of QTL affecting fatty acid composition in the pig显示文摘 | Alex Clop Cristina Ovilo Miguel Perez-Enciso Albert Cercos Anna Tomas Ana Fernandez Agustina Coll Josep M. Folch Carmen Barragan Isabel Diaz Maria A. Oliver Luis Varona Luis Silio Armand Sanchez Jose L. Noguera | 2003 | Mammalian Genome2003，，9： | 1 |
| 4 | Alcohol Oxidation by Dioxygen and Aldehydes Catalysed by Square - Planar Cobalt(III) Complexes of Disubstituted Oxamides and Related Ligands 显示文摘 | Isabel Fernandez Jose R Pedro Antonio L Rosello | 2001 | Eur J Org Chem2001，，7： | 1 |
| 5 | Strategic procurement outsourcing: a paradox in current theory显示文摘 | Tauno Kekale Isabel Fernandez | 2007 | International Journal of Preurement Man- agement2007，，1： | 1 |
| 6 | Detection of QTL affecting fatty acid composition in the pig显示文摘 | Alex Clop Cristina Ovilo Miguel Perez-Enciso Albert Cercos Anna Tomas Ana Fernandez Agustina Coll Josep M. Folch Carmen Barragan Isabel Diaz Maria A. Oliver Luis Varona Luis Silio Armand Sanchez Jose L. Noguera | 2003 | Mammalian Genome2003，，9： | 1 |
| 7 | Vasoactive intestinal peptide (VIP) induces malignant transformation of the human prostate epithelial cell line RWPE-1显示文摘 | FERNANDEZ MARTINEZ A B BAJO A M ISABEL A M | 2010 | Cancer Lett2010，299，1： | 1 |
| 8 | Population assessment and habitat associations of the Visayan Hornbill(Penelopides panini)in Northwest Panay,Philippines显示文摘Background:Seven out of ten hornbill species in the Philippines are threatened with extinction.Among these is the endangered Visayan Hornbill(Penelopides panini),found on the islands of Panay and Negros.Threatened by habitat loss and hunting,its population size is thought to have declined from 1800 individuals 20 years ago to less than 1000.However,a recent study on Negros estimated 3564 individuals across three core forest blocks.This study aims to quantify the Visayan Hornbill population size in and around the Northwest Panay Peninsula Natural Park(NWPPNP)on Panay,the largest contiguous low-elevation forest landscape remaining across its range,and its broad habitat associations across a gradient of environmental degradation.Methods:Hornbills were surveyed using 10-min distance sampling point counts(n=367)along transects(average length 1.1 km).Environmental variables were recorded along transects,while habitat was classified into primary forest,secondary forest,plantation,or open habitat.Distance software was used to estimate population densities stratified by habitat,with the overall population estimate taken as a mean of habitat density estimates weighted by habitat area.Using generalized linear mixed models,hornbill occurrence was modelled using combinations of nine environmental variables as main and two-way fixed effects.Results:Surveys covered 204.4 km^(2) of the 374.8 km^(2) Northwest Panay Peninsula.Hornbills were not recorded in plantations or open habitats.Hornbill density was significantly higher in primary forest(17.8 individuals/km~2±26.9%CV)than in secondary forest(3.7 individuals/km^(2)±33.2%CV;z=15.212,P<0.001).The overall population estimate for the NWPPNP and environs is 2109 individuals,and 2673 individuals for the entire Northwest Panay Peninsula.Hornbill presence was best explained by a model including distance from the Park boundary alongside five interaction effects and transect as a random effect.Distance,and the interaction between distance and medium-sized trees were significant predictors of hornbill presence.Conclusions:Our study evidences the habitat preference of the Visayan Hornbill,highlights the importance of the NWPPNP for the species'conservation,and provides strong evidence for re-assessing the global population size. | Holly Isabelle Mynott David Charles Lee Rhea Aranas Santillan Christian Jürgen Schwarz Benjamin Tacud Arcel Dryden Fernandez Daphne Kerhoas | 2021 | Avian Research2021，12，4： | 0 |
| 9 | Assessment of Soil Water Content and Remote Sensing Techniques--Case Study of Kiwi Orchard (Portugal)显示文摘 | Celestina Maria Gago Pedras | 2014 | Journal of Agricultural Science and Technology(A)2014，4，1： | 0 |
| 10 | Effectiveness and safety of first-generation protease inhibitors in clinical practice:Hepatitis C virus patients with advanced fibrosis显示文摘AIM:To evaluates the effectiveness and safety of the first generation,NS3/4A protease inhibitors(PIs) in clinical practice against chronic C virus,especially in patients with advanced fibrosis. METHODS:Prospective study and non-experimental analysis of a multicentre cohort of 38 Spanish hospitals that includes patients with chronic hepatitis C genotype 1,treatment-na?ve(TN) or treatment-experienced(TE),who underwent triple therapy with the first generation NS3/4A protease inhibitors,boceprevir(BOC) and telaprevir(TVR),in combination with pegylated interferon and ribavirin. The patients were treatment in routine practice settings. Data on the study population and on adverse clinical and virologic effects were compiled during the treatment period and during follow up.RESULTS:One thousand and fifty seven patients were included,405(38%) were treated with BOC and 652(62%) with TVR. Of this total,30%(n = 319) were TN and the remaining were TE:28%(n = 298) relapsers,12%(n = 123) partial responders(PR),25%(n = 260) null-responders(NR) and for 5%(n = 57) with prior response unknown. The rate of sustained virologic response(SVR) by intention-to-treatment(ITT) was greater in those treated with TVR(65%) than in those treated with BOC(52%)(P < 0.0001),whereas by modified intention-to-treatment(m ITT) no were found significant differences. By degree of fibrosis,56% of patients were F4 and the highest SVR rates were recorded in the non-F4 patients,both TN and TE. In the analysis by groups,the TN patients treated with TVR by ITT showed a higher SVR(P = 0.005). However,by m ITT there were no significant differences between BOC and TVR. In the multivariate analysis by m ITT,the significant SVR factors were relapsers,IL28 B CC and non-F4; the type of treatment(BOC or TVR) was not significant. The lowest SVR values were presented by the F4-NR patients,treated with BOC(46%) or with TVR(45%). 28% of the patients interrupted the treatment,mainly by non-viral response(51%):this outcome was more frequent in the TE than in the TN patients(57% vs 40%,P = 0.01). With respect to severe haematological disorders,neutropaenia was more likely to affect the patients treated with BOC(33% vs 20%,P ≤ 0.0001),and thrombocytopaenia and anaemia,the F4 patients(P = 0.000,P = 0.025,respectively). CONCLUSION:In a real clinical practice setting with a high proportion of patients with advanced fibrosis,effectiveness of first-generation PIs was high except for NR patients,with similar SVR rates being achieved by BOC and TVR. | Javier Salmeron Carmen Vinaixa Ruben Berenguer Juan Manuel Pascasio Juan Jose Sanchez Ruano Miguel angel Serra Ana Gila Moises Diago Manuel Romero-Gomez Jose Maria Navarro Milagros Testillano Conrado Fernandez Dolores Espinosa Isabel Carmona Jose Antonio Pons Francisco Jorquera Francisco Javier Rodriguez Ramon Perez Jose Luis Montero Rafael Granados Miguel Fernandez Ana Belen Martin Paloma Munoz de Rueda Rosa Quiles | 2015 | World Journal of Gastroenterology2015，21，30： | 0 |
| 11 | Betas Used by Professors: A Survey With 2,500 Answers显示文摘 | Pablo Fernandez Isabel Femandez Acin | 2016 | China-USA Business Review2016，15，7： | 0 |
| 12 | Performance of the Multiprofessional Team in Cytoreductive Surgeries with Intraperitoneal Hyperthermic Chemotherapy:Experience Reporting显示文摘Purpose:This study aims at reporting the experience of a cancer hospital’s multiprofessional team with surgery patients in performing cytoreductive surgeries associated with hyperthermic intraperitoneal chemotherapy.Methods:It is a reporting about the experience of the multiprofessional team at AC Camargo Cancer Center’s surgery center,which operates in cytoreductive surgeries with hyperthermic intraperitoneal chemotherapy,thus guaranteeing the surgery patient’s safety.Results:No safety report for the surgery patient subjected to intraperitoneal hypothermic chemotherapy was found in the literature.Therefore,the surgery center’s multiprofessional team’s practice was based on standards for manipulating chemotherapeutic agents and for safely administering medication.A checklist was elaborated for cytoreductive surgeries with hyperthermic intraperitoneal chemotherapy based on the surgery patient safety protocol and the institution’s multiprofessional team’s experience.Conclusions:From the multiprofessional team’s experiences in cytoreductive surgeries with hyperthermic intraperitoneal chemotherapy,the importance of elaborating a checklist to promote the quality of assistance and guarantee patient safety during the entire intraoperative phase became evident. | Cecília da Silva Angelo(RN) Ademar Lopes(PhD) Catharina Ferreira de Meira Pachioni(MSc) Eduardo Henrique Giroud Joaquim(MSc) Samuel Aguiar Junior(PhD) Gustavo Cardoso Guimaraes(PhD) Glauco Baiocchi Neto(PhD) Felipe JoséFernandez Coimbra(PhD) Isabel Miranda Bonfim(MSc) Rita de Cassia Burgos de Oliveira(PhD) Tailine Ligia Tadini(RN) | 2018 | Journal of Pharmacy and Pharmacology2018，6，11： | 0 |
| 13 | 奥米纽姆摩天大楼显示文摘法兰克福是一座集欧洲古典街区与当代大都市高楼于一体的城市,在城市中心形成了一个充满生机的建筑群落。这种建筑上的结合提供了紧密与动态变化的天际线,与连接法兰克福北部的陶纳斯山脉遥相呼应。奥米纽姆大厦位于城市中建筑高低混合区域的中心,通过周围的环境和建筑来提供一个合理的、具有雕塑感的剪影。BIG建议设计一座塔楼. | Dominic James Black David Verbeek Gunther Weber Helen Chen Joanna Gajda Joseph James Haberl Lukas Kerner Maria Teresa Fernandez Rojo Natalie Isabel Stachnik Nicolas Millot Sabine Kokina Thomas Sebastian Krall Viktoria Millentrup Yan Ma Emily King Enea Michelesio Gabriel■ Ubarevi■iūt■ Giedrius Mamavicius Jesper Boye Andersen Jakob Lange Joanna Jakubowska Katarzyna Joanna Piekarczyk Julieta Muzillo Lorenzo Boddi Lucas Carriere Lucian Tofan Max Aldunate Reitour Raphael Cirani Sabine Kokina Tore Banke Frank Dinger Nils Koenning 陈思瑾(译) | 2019 | 城市环境设计2019，0，2： | 0 |
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