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| 1 | Survival of geriatric patients after percutaneous endoscopic gastrostomy in Japan显示文摘AIM: To examine the long term survival of geriatric patients treated with percutaneous endoscopic gastrostomy (PEG) in Japan. METHODS: We retrospectively included 46 Japanese community and tertiary hospitals to investigate 931 consecutive geriatric patients (≥ 65 years old) with swallowing difficulty and newly performed PEG between Jan 1st 2005 and Dec 31st 2008. We set death as an outcome and explored the associations among patient’s characteristics at PEG using log-rank tests and Cox proportional hazard models. RESULTS: Nine hundred and thirty one patients were followed up for a median of 468 d. A total of 502 deaths were observed (mortality 53%). However, 99%, 95%, 88%, 75% and 66% of 931 patients survived more than 7, 30, 60 d, a half year and one year, respectively. In addition, 50% and 25% of the patients survived 753 and 1647 d, respectively. Eight deaths were considered as PEG-related, and were associated with lower serum albumin levels (P = 0.002). On the other hand, among 28 surviving patients (6.5%), PEG was removed. In a multivariate hazard model, older age [hazard ratio (HR), 1.02; 95% confidence interval (CI), 1.00-1.03; P = 0.009], higher C-reactive protein (HR, 1.04; 95% CI: 1.01-1.07; P = 0.005), and higher blood urea nitrogen (HR, 1.01; 95% CI: 1.00-1.02; P = 0.003) were significant poor prognostic factors, whereas higher albumin (HR, 0.67; 95% CI: 0.52-0.85; P = 0.001), female gender (HR, 0.60; 95% CI: 0.48-0.75; P < 0.001) and no previous history of ischemic heart disease (HR, 0.69; 95% CI: 0.54-0.88, P = 0.003) were markedly better prognostic factors. CONCLUSION: These results suggest that more than half of geriatric patients with PEG may survive longer than 2 years. The analysis elucidated prognostic factors. | Yutaka Suzuki Seryna Tamez Akihiko Murakami Akihiko Taira Akihiro Mizuhara Akira Horiuchi Chie Mihara Eiji Ako Hirohito Muramatsu Hitoshi Okano Hitoshi Suenaga Kazuaki Jomoto Junya Kobayashi Katsunari Takifuji Kazuhiro Akiyama Koh Tahara Koji Onishi Makoto Shimazaki Masami Matsumoto Masashi Ijima Masato Murakami Masato Nakahori Michiaki Kudo Michio Maruyama Mikako Takahashi Naohiro Washizawa Shigeru Onozawa Satoshi Goshi Satoyoshi Yamashita Shigeki Ono Shin Imazato Shinji Nishiwaki Shuichirou Kitahara Takao Endo Takao Iiri Takeshi Nagahama Takuto Hikichi Tatsuya Mikami Tetsuo Yamamoto Tetsushi Ogawa Tomoko Ogawa Tomoyuki Ohta Toshifumi Matsumoto Toshiroh Kura Tsutomu Kikuchi Tsuyoshi Iwase Tsuyotoshi Tsuji Yukio Nishiguchi Mitsuyoshi Urashima | 2010 | World Journal of Gastroenterology2010，16，40： | 4 |
| 2 | Influence of resin monomers on growth of oral streptococci显示文摘 | Takahashi Y Imazato S Russell RR | 2004 | J Dent Res2004，83，4： | 1 |
| 3 | In vivo antibacterial effect of dentin primer incorporating MDPB显示文摘 | Kaneko T Imazato S Ebi N | 2001 | J Dent Res2001，80，： | 1 |
| 4 | Inhibition of root caries progression by an antibacterial adhesive显示文摘 | Kuramoto A Imazato S Wal s AW | | 0，，： | 1 |
| 5 | Partial Mastoid Oblitera- tion Combined With Soft-wall Reconstruction for Middle Ear Chol- esteatoma显示文摘 | Suzuki H Ikezaki S Imazato K | 2014 | Ann Otol Rhinol Laryngol2014，123，8： | 1 |
| 6 | Degree of conversion of composites measured by DTA and FTIR 显示文摘 | Imazato S Mccabe J F Tarumi H | 2001 | Dent Mater2001，17，2： | 1 |
| 7 | Incorporation of bacterial inhibitor into resin composite显示文摘 | Imazato S Torii M Tsuchitani Y | 1994 | J Dent Res1994，73，8： | 1 |
| 8 | Fracture Resistance of Pulpless Teeth Restored with Post cores and Crowns显示文摘 | Mikako Hayashi Yutaka Takahashi Satoshi Imazato | 2006 | Dental Materials2006，22，5： | 1 |
| 9 | Internally balanced magnet unit 显示文摘 | Hirose S Imazato M KuDo Y | 1986 | Advanced Robotics1986，1，3： | 1 |
| 10 | Fluoride released from glass ionomer cement is responsible to inhibit the acid production of carie-related oral streptococci显示文摘 | Nakajo K Imazato S Takahashi Y | 2009 | Dent Mater2009，25，6： | 1 |
| 11 | Bio-active restorative materials with antibacteri- al effects: new dimension of innovation in restorative dentist- ry显示文摘 | Imazato S | 2009 | Dent Mater J2009，28，1： | 1 |
| 12 | 显示文摘 | Imazato Satoshi Kinomoto Yoshifumi Tarumi Hisashi | 2003 | Dental Materials2003，19，4： | 1 |
| 13 | Inhibitory effects of resin composite conaining bactericide-immobilized fil er on plaque accumulation显示文摘 | Ebi N Imazato S Noiri Y | | 0，，06： | 1 |
| 14 | 显示文摘 | Imazato Satoshi | 2003 | Dental Materials2003，19，44： | 1 |
| 15 | Degree of Conversion of Composites Measured by DTA and FTIR显示文摘 | Imazato S Mccabe J F Tarumi H | 2001 | Dent Mater2001，17，2： | 1 |
| 16 | Incorporation of bacterial inhibitor into resin composite显示文摘 | Imazato S Torii M Tsuchitani Y | 1994 | J Dent Res1994，73，8： | 1 |
| 17 | Antibacterial activity of bactericide-immobilized filler for resin-based restoratives显示文摘 | Imazato S Ebi N Takahashi Y | 2003 | Biomaterials2003，24，20： | 1 |
| 18 | Bactericidal activity and cytotoxicity of antibacterial monomer MDPB显示文摘 | Imazato S Ebi N Tarumi H | 1999 | Biomaterials1999，20，9： | 1 |
| 19 | In vitro analysis of inhibitory effects of the antibacterial monomer MDPB-containing restorations on the progression of secondary root caries显示文摘 | Thome T Mayer MP Imazato S | 2009 | J Dent2009，37，9： | 1 |
| 20 | Effects of dual antibacterial a- gents MDPB and nano - silver in primer on microcosm biofilm, cytotox-icity and dentine bond properties 显示文摘 | Zhang K Cheng L Imazato S | 2013 | Journal of Dentistry2013，41，5： | 1 |
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