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| 1 | 2型糖尿病消瘦患者预后差显示文摘由于常将体质指数(BMI)〈18 kg/m^2患者排除在外,以往研究中关于BMI与糖尿病死亡率之间的关系不一定能全面反映整个人群的情况。为此,来自日本东京大学公共卫生学院的Hirohito Sone教授及其团队进行了一项研究,调查2型糖尿病患者BMI与死亡率之间的关系。该研究结果在线发表于2014年9月9日的The Journal of Clinical Endocrinology&Metabolism杂志。 | Tanaka S Iimuro S | 2014 | 中国全科医学2014，17，32： | 13 |
| 2 | Prospective postsurgical capsule endoscopy in patients with Crohn's disease显示文摘AIM: To clarify the usefulness of postsurgical capsule endoscopy(CE) in the diagnosis of recurrent small bowel lesions of Crohn's disease(CD). METHODS: This prospective study included 19 patients who underwent ileocolectomy or partial ileal resection for CD. CE was performed 2-3 wk after surgery to check for the presence/absence and severity of lesions remaining in the small bowel, and for any recurrence at the anastomosed area. CE was repeated 6-8 mo after surgery and the findings were compared with those obtained shortly after surgery. The Lewis score (LS) was used to evaluate any inflammatory changes of the small bowel. RESULTS: One patient was excluded from analysis because of insufficient endoscopy data at the initial CE. The total LS shortly after surgery was 428.3 on average(median, 174; range, 8-4264), and was ≥ 135(active stage) in 78%(14 of 18) of the patients. When the remaining unresected small bowel was divided into 3 equal portions according to the transition time(proximal, middle, and distal tertiles), the mean LS was 286.6, 83.0, and 146.7, respectively, without any significant difference. Ulcerous lesions in the anastomosed area were observed in 83% of all patients. In 38% of the 13 patients who could undergo CE again after 6-8 mo, the total LS was higher by ≥ 100 than that recorded shortly after surgery, thus indicating a diagnosis of endoscopic progressive recurrence. CONCLUSION: Our pilot study suggests that CE can be used to objectively evaluate the postoperative recurrence of small bowel lesions after surgery for CD. | Tomoaki Kono Nobuyuki Hida Koji Nogami Masaki Iimuro Yoshio Ohda Yoko Yokoyama Koji Kamikozuru Katsuyuki Tozawa Mikio Kawai Tomohiro Ogawa Kazutoshi Hori Hiroki Ikeuchi Hiroto Miwa Shiro Nakamura Takayuki Matsumoto | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，3： | 7 |
| 3 | Scheduled infliximab monotherapy to prevent recurrence of Crohn’s disease following ileocolic or ileal resection: A 3‐year prospective randomized open trial显示文摘 | Koji Yoshida Ken Fukunaga Hiroki Ikeuchi Koji Kamikozuru Nobuyuki Hida Yoshio Ohda Yoko Yokoyama Masaki Iimuro Naohisa Takeda Kyoichi Kato Risa Kikuyama Kazuko Nagase Kazutoshi Hori Shiro Nakamura Hiroto Miwa Takayuki Matsumoto | 2011 | Inflamm Bowel Dis2011，，9： | 2 |
| 4 | c-Jun does not me diate hepatocyte apoptosis following NF-kappaB inhibi tion and partial hcpatectomy显示文摘 | Schrum I W Black D Iimuro Y | 2000 | J Surg Res2000，88，2： | 1 |
| 5 | A diet containing glycine improves survival in endotoxin shock in the rat显示文摘 | Iimuro Y Forman DT | 1996 | Am J Physiol1996，271，1： | 1 |
| 6 | Selective inactivation of NF-kappaB in the liver using NF-kappaB decoy suppresses CCL4-induced liver injury and fibrosis显示文摘 | Son G Iimuro Y Seki E | 2007 | Am J Physiol Gastrointest Liver Physiol2007，293，3： | 1 |
| 7 | Small hepatocellu- lar carcinoma: comparison of radio-frequency ablation and percutaneous microwave coagulation therapy 显示文摘 | Shibata T Iimuro Y Yamamoto Y | 2002 | Radiology2002，223，2： | 1 |
| 8 | Small hepatocellular carcinoma:comparison of radio-frequency ablation and percutaneous microwave coagulation therapy显示文摘 | Shibata T Iimuro Y Yamamoto Y | 2002 | Radoiology2002，223，2： | 1 |
| 9 | Waist circumference as a cardiovascular and metabolic risk in Japanese patients with type 2 diabetes显示文摘 | Sone H Tanaka S Iimuro S | 2009 | Obesity (Silver Spring)2009，17，3： | 1 |
| 10 | Primary hepatic car- cinoid tumor with metachronous lymph node metastasis after long-term follow up 显示文摘 | Iimuro Y Deguchi Y Ueda Y | 2002 | Gastroenterol Hepatol2002，17，11： | 1 |
| 11 | Small hepa- tocellular carcinoma: comparison of radio -frequency ablation and percutaneous microwave coagulation therapy显示文摘 | SHIBATA T IIMURO Y YAMAMOTO Y | 2002 | Radi- ology2002，223，2： | 1 |
| 12 | Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats 显示文摘 | Kinoshita K Iimuro Y Otogawa K | 2007 | Gut2007，56，5： | 1 |
| 13 | Lower physical activity is a strong predictor of cardiovascular events in elderly patients with type2 diabetes mellitus beyond traditional risk factors:The Japanese elderly diabetes intervention trial显示文摘 | Iijima K Iimuro S Shinozaki T | 2012 | Geriatrics&Gerontology International2012，12，1： | 1 |
| 14 | Small hepatocellular carcinoma: comparison of radio-frequency ablation and percutaneous microwave coagulation therapy显示文摘 | SHIBATA T IIMURO Y YAMAMOTO Y | 2002 | Radiology2002，223，2： | 1 |
| 15 | Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an Ikap-paB super-repressor显示文摘 | Hellerbrand C Jobin C Iimuro Y etal | 1998 | Hepatology1998，27，5： | 1 |
| 16 | Small hepatocellular carcinoma : comparison of radio-frequency ablation and pereutaneous microwave coagulation therapy 显示文摘 | Shibata T Iimuro Y Yamamoto Y | 2002 | Radiology2002，223，2： | 1 |
| 17 | Adenovirus-me- diated expression of BMP-7 suppresses the development of liver fibrosis in rats显示文摘 | Kinoshita K Iimuro Y Otogawa K | 2007 | Gut2007，56，： | 1 |
| 18 | Angiogenic effects of adrenomedullin in ischemia and tumor growth 显示文摘 | Iimuro S Shindo T Moriyama N | 2004 | Circ Res2004，95，4： | 1 |
| 19 | Preoperative esti mation of asialoglycoprotein receptor expression in the remnant liver from CT/99mTc-GSA SPECT fusion images correlates well with postoperative liver function parameters显示文摘 | Iimuro Y Kashiwagi T Yamanaka J | 2010 | J Hepa tobiliary Pancreat Sci2010，17，： | 1 |
| 20 | Adenovirus-mediated expression of BMP -7suppresses the development of liver fibrosis in rats 显示文摘 | Kinoshita K Iimuro Y Otogawak K | 2007 | Gut2007，56，： | 1 |
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