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| 1 | NAT2 polymorphism in Omani gastric cancer patients-risk predisposition and clinicopathological associations显示文摘AIM: To study whether N-acetyltransferase 2 (NAT2) genotypes and phenotypes are associated with increased risk factor for gastric cancer in Omani patients and to study the clinico-pathological correlations and the prognostic signifi cance of NAT2.METHODS: Genomic DNA was extracted from peripheral blood of 100 gastric cancer patients and 100 control subjects. NAT2 genotyping was performed using DNA sequencing. The prognostic significance of NAT2 and other clinicopathological features was assessed by univariate and multivariate analyses.RESULTS: We observed no significant association between NAT2 genotypes and phenotypes and gastric cancer risk. The NAT2 phenotype polymorphisms and gastric cancer risk predisposition were not modified by concomitant H pylori infection and smoking. There was no significant association between NAT2 and clinicopathological features, and NAT2 had no independent prognostic signifi cance.CONCLUSION: In the current study, NAT2 genotypes and phenotypes are not associated with gastric cancer risk predisposition. Moreover NAT2 phenotypes had no clinicopathological associations or prognostic signif icance. | Mansour S Al-Moundhri Mohamed Al-Kindi Maryam Al-Nabhani Bassim Al-Bahrani Ikram A Burney Ali Al-Madhani Shyam S Ganguly Misbah Tanira | 2007 | World Journal of Gastroenterology2007，13，19： | 5 |
| 2 | Association of E-cadherin (CDH1) gene polymorphisms and gastric cancer risk显示文摘AIM:To investigate the associations between CDH1 gene polymorphisms and gastric cancer(GC) risk predisposition.METHODS:We analyzed four CDH1 polymorphisms(+54 T>C,-160 C>A,-616 G>C,-3159 T>C) in an Omani population,by extraction of genomic DNA from the peripheral blood of 192 patients with GC and 170 control participants and performed CDH1 genotyping using DNA sequencing.RESULTS:CDH1-160-AA genotype was associated with an increased risk of GC(OR = 3.6,95% CI:1.1-11.8)(P = 0.03).There was no significant association between the other polymorphisms and GC risk.The haplotype analysis of +54 T>C,-160 C>A,-616 G>C,-3159 T>C genotypes revealed that the OR of CCGC and CAGC haplotypes was 1.5(95% CI:0.7-3.5) and 1.5(95% CI:0.2-3.0),but did not reach statistical significance.CONCLUSION:The current study suggests that the-160 AA genotype was associated with an increased risk of GC in Oman. | Mansour S Al-Moundhri Manal Al-Khanbashi Mohammed Al-Kindi Maryam Al-Nabhani Ikram A Burney Abdulaziz Al-Farsi Bassim Al-Bahrani | 2010 | World Journal of Gastroenterology2010，16，27： | 4 |
| 3 | Evaluation of BACTEC MGIT960 system for recovery of Mycobacterium tuberculosis complex in Pakistan显示文摘 | Satti L Ikram A Abbasi S | 2010 | Malaysian J Microbool2010，6，2： | 1 |
| 4 | Incidence of cerebral microbleeds in the general population:the Rotterdam scan study显示文摘 | Poels M M Ikram M A van der Lugt A | 2011 | Stroke2011，42，： | 1 |
| 5 | Cerebral microbleeds are associated with worse cognitive function:the Rotterdam Scan Study显示文摘 | Poels MM Ikram MA Vander-Lugt A | 2012 | Neurology2012，78，5： | 1 |
| 6 | Predisposingfactors to industrial hand injuries in Saudi Arabia显示文摘 | AL ZAHRANI S IKRAM M A AL-QATTAN M M | 1997 | J Hand SurgBr1997，22，1： | 1 |
| 7 | Prev-alence and risk factors of cerebral microbleeds: the Rot- terdam Scan Study 显示文摘 | Vernooij M W van der Lugt A Ikram M A | 2008 | Neurology2008，70，14： | 1 |
| 8 | An outbreak of multi-drug resistant Escherichia coli urinary tract infection in an elderly population:a case-control study of risk factors显示文摘 | Ikram R Psutka R Carter A | 2015 | BMC Infect Dis2015，9，15： | 1 |
| 9 | Prevalence and risk factors of cerebral microbleeds: the Rotterdam scan study 显示文摘 | Vernooij MW van der Lugt A Ikram MA | 2008 | Neurology2008，70，： | 1 |
| 10 | Cerebral microbleeds are associated with worse cognitive function:the Rotterdam scan study显示文摘 | Poels MM Ikram MA van der Lugt A | | 0，，： | 1 |
| 11 | Prevalence and risk factors of cerebral microbleeds:The Rotterdam scan study显示文摘 | Vernooij MW van der Lugt A Ikram MA | | 0，，： | 1 |
| 12 | Resource efficient implementation of T-boxes in AES on Virlex- 5 FPGA 显示文摘 | KUNDI D S AZIZ A IKRAM N | 2010 | Information Processing LeRers2010，110，10： | 1 |
| 13 | Prevalence and risk factors of cerebral microbleeds:an update of the Rotterdam scan study显示文摘 | POELS M M VERNOOIJ M W IKRAM M A | 2010 | Stroke a Journal of Cerebral Circulation2010，41，10： | 1 |
| 14 | First-principles calculations of structural,electronic and optical properties of Cdx Zn1-xS alloys显示文摘 | Noor N A Ikram N Ali S | 2010 | Journal of Alloys and Compounds2010，507，2： | 1 |
| 15 | Evaluation of insulin sensitivity and glucose effectiveness during a standardized break-fast test:comparison with the minimal model analysis of an intravenous glucose tolerance test显示文摘 | IKRAM A JEAN-FREDERIC B JACQUES M | 2006 | Metabolism2006，55，5： | 1 |
| 16 | Incidence of cere-bral microbleeds in the general populatiomthe Rotterdam ScanStudy显示文摘 | Poels MMF Ikram MA van der Lugt A | 2011 | Stroke2011，42，： | 1 |
| 17 | Effect of permanent and temporary immersion on banana micro-propagation 显示文摘 | IKRAM U A MUHAMMAD U D | 2007 | Pak J Bot2007，39，5： | 1 |
| 18 | Prevalence and risk factors of cerebral microbleeds: an update of the Rotter dam scan study显示文摘 | POELS M M VERNOOIJ M W IKRAM M A | 2010 | Stroke2010，41，10： | 1 |
| 19 | Prevalence andrisk factors of cerebral microbleeds 显示文摘 | Vernooij MW van der Lugt A Ikram MA | 2008 | Neurology2008，70，： | 1 |
| 20 | Differential inhibition of human oolon cancer cells by structurally similar flavonoids of citrus显示文摘 | Murthy K N C Kim J V ikram A | | 0，，： | 1 |
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