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| 1 | Dual-specificity phosphatase 6(DUSP6): a review of its molecular characteristics and clinical relevance in cancer显示文摘Mitogen-activated protein kinases(MAPKs) are the main regulators of cellular proliferation, growth, and survival in physiological or pathological conditions. Aberrant MAPK signaling plays a pivotal role in carcinogenesis, which leads to development and progression of human cancer. Dual-specificity phosphatase 6(DUSP6), a member of the MAPK phosphatase family, interacts with specifically targeted extracellular signal-regulated kinase 1/2 via negative feedback regulation in the MAPK pathway of mammalian cells. This phosphatase functions in a dual manner, pro-oncogenic or tumor-suppressive, depending on the type of cancer. To date, the tumor-suppressive role of DUSP6 has been demonstrated in pancreatic cancer, non-small cell lung cancer, esophageal squamous cell and nasopharyngeal carcinoma, and ovarian cancer. Its pro-oncogenic role has been observed in human glioblastoma, thyroid carcinoma, breast cancer, and acute myeloid carcinoma. Both roles of DUSP6 have been documented in malignant melanoma depending on the histological subtype of the cancer. Loss-or gain-of-function effects of DUSP6 in these cancers highlights the significance of this phosphatase in carcinogenesis. Development of methods that use the DUSP6 gene as a therapeutic target for cancer treatment or as a prognostic factor for diagnosis and evaluation of cancer treatment outcome has great potential. This review focuses on molecular characteristics of the DUSP6 gene and its role in cancers in the purview of development, progression, and cancer treatment outcome. | Muhammad Khairi Ahmad Nur Ainina Abdollah Nurul Husna Shafie Narazah Mohd Yusof Siti Razila Abdul Razak | 2018 | Cancer Biology & Medicine2018，15，1： | 6 |
| 2 | Migrating fish bone piercing the common carotid artery,thyroid gland and causing deep neck abscess显示文摘Foreign body(FB) ingestion is very common in Malaysian population.The most commonly ingested FB is fish bone.Common presenting symptoms include FB sensation,odynophagia and or sharp pricking pain during swallowing.A careful history and physical examination is very important.Despite negative laryngoscopy and rigid esophagoscopy,persistent symptoms warrants further radiographic imaging studies.The FB can migrate extraluminally and involve other important adjacent structures of the neck and along the digestive tract.We report 3 cases of extraluminal migration of fish bone and their complications,which were successfully managed.One case with vascular complication which involve common carotid artery and the other two cases with neck abscess formation involving thyroid gland,retropharyngeal and parapharyngeal abscess. | Hafizah Husna Johari Bee-Lian Khaw Zulkifli Yusof Irfan Mohamad | 2016 | World Journal of Clinical Cases2016，4，11： | 2 |
| 3 | Effects of Purified Salvia Mihiorrhiza Extract on Cardiac Vascular Smooth Muscle Hypoxic Ceils 显示文摘 | Husna B On T Zhu Y Z | 2007 | J Pharmacol Sci2007，104，3： | 1 |
| 4 | Enhancement of ant colony optimiza- tion for grid load balancing 显示文摘 | Ku Ruhana Ku-Mahamud Aniza Mohamed Din Husna Jamal Abdul Nasir | 2011 | European Journal of Scientific Research2011，64，1： | 1 |
| 5 | Textile Effluent Discoloration by Immobilized Phanerochaete chrysosporium into PVA-algi- nate-sulfate beads显示文摘 | HUSNA N A NASIR A | 2013 | Journal Teknologi2013，62，2： | 1 |
| 6 | Textile efflu-ent discoloration by immobilized phanerochaete chrysos-porium into PVA-alginate-sulfate beads显示文摘 | Nor Atikah Husna Ahmad Nasir Nor Fadhilatul ShillaMohd Asri Nor Azimah Mohd Zain | 2013 | Journal Te-knologi(Sciences Engineering)2013，62，2： | 1 |
| 7 | A recent review on phytochemical constituents and medicinal properties of kesum(Polygonum minus Huds.)显示文摘Medicinal plants and herbal preparations are gaining renowned interest in scientific communities nowadays due to their reliable pharmacological actions and affordability to common people which makes them effective in control of various diseases.Polygonum minus(Polygonaceae)locally known as kesuni is an aromatic plant commonly used in Malay delicacies.The plant is having potential applications due to its high volatile oil constituents in perfumes and powerful antioxidant activity.It has been used traditionally to treat various ailments including dandruff.The research has been carried out by various researchers using different in vitro and in vivo models for biological evaluations to support these claims.This review paper may help upcoming research activities on Polygonum minus by giving up to date information on the phytochemical constituents and medicinal properties of kesum to a possible extent with relevant data. | Paritala Vikram Kishore Kumar chiruvella Ilfah Husna Abdullah Ripain Mohammed Arifullah | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，6： | 1 |
| 8 | Advanced VOCs decomposition method by gliding arc plasma 显示文摘 | Antonius lndarto Dae Ryook Yang Che Husna Azhari | 2007 | Chemical Engineer- ing Journal2007，131，13： | 1 |
| 9 | Effects of purified Salvia miltiorrhizae extract on cardiac vascular smooth muscle hypoxic ceils显示文摘 | Husna B On T Zhu YZ | 2007 | J Pharmacol Sci2007，104，3： | 1 |
| 10 | Do knowledge and clinical experi- ence have specific roles in perceived clinical skills for tsunami care a- mong nurses in Banda Aceh, Indonesia 显示文摘 | Husna C Hatthakit U Chaowalit A | 2011 | Aust Emerg Nurs J2011，14，2： | 1 |
| 11 | Enhancement of ant colony optimization for gridload balancing 显示文摘 | Ku Ruhana Ku-Mahamud? Aniza Mohamed Din Husna JamalAbdul Nasir | 2011 | European Journal of Scientific Research2011，64，1： | 1 |
| 12 | Influence of annealing temperature on the properties of ZnO thin films grown by sputtering显示文摘 | Husna J Aliyu M M Islam M A | 2012 | Energy Proeedia2012，25，： | 1 |
| 13 | Signalling mechanisms in the regulation of vascular cell migration显示文摘 | Husna Abedi Ian Zachary | 1995 | Cardiovase Res1995，30，4： | 1 |
| 14 | Improved 4H-SiC MOS Interfaces Produced via Two Independent Processes: Metal Enhanced Oxidation and 1300oC NO Anneal显示文摘 | Das Mrinal K. Hull Brett A. Krishnaswami Sumi Husna Fatima Haney Sarah K. Lelis Aivars J. Scozzie Charles J. Scofield James D | 2006 | 2006 (527)2006，，527： | 1 |
| 15 | Characteristics,causality,and suicidal behavior:a qualitative study of family members with suicide history in Wonogiri,Indonesia显示文摘Objective:This study explored the characteristics,causality,and suicidal behavior among family members with suicide history in Wonogiri,Central Java,Indonesia.Methods:Qualitative semistructured interviews were conducted with 15 family members who had made suicide attempts.The interviews directly explored the relationships among characteristics,causality,and suicidal behavior.The research data were analyzed using the Miles and Huberman approach.Results:The results indicate that there are relationships among characteristics,causality,and suicidal behaviors.The characteristics contributing to suicide attempts were male gender,age(adolescence and old age),lack of religious activities,introvert nature,low economic status,chronic diseases,unemployment,and a history of family members with suicide attempts.The causality of suicide was joblessness,economic crisis,unemployment,family conditions,personality disorder,depression,sickness,and suicide ideation.Conclusions:The findings highlight the relationships among characteristics,causality,and suicidal behaviors.Suicide occurs when individuals have some problems that they cannot solve because of the lack of family support.The causal factors were related to one another,which caused the suicidal behavior.One of the most effective suicide prevention strategies is educating the community on how to identify suicidal signs and increase social supports. | Susana Nurtanti Sri Handayani Nita Yunianti Ratnasari Putri Halimu Husna Tantut Susanto | 2020 | Frontiers of Nursing2020，7，2： | 0 |
| 16 | The potential of arbuscular mycorrhizal fungi to conserve Kalappia celebica,an endangered endemic legume on gold mine tailings in Sulawesi,Indonesia显示文摘Kalapi(Kalappia celebica)is an endemic legume of Sulawesi and has been included in the endangered category since the early 1980s.Conservation of the species is possible through ex situ culture techniques.Arbuscular mycorrhizal fungi(AMF)can accelerate plant growth which in turn supports the conservation of endangered species.This study aimed to assess the efficacy of local AMF to accelerate the growth of kalapi and increase nutrient uptake in kalapi grown in gold mine tailing media.There were three AMF treatments,Glomus claroideum,Glomus coronatum,and a mixture of both,plus the control.Each treatment was replicated three times,each consisting of five plants.The results show that the highest AMF colony was obtained by kalapi seedlings inoculated with Glomus coronatum and the mixture of AMF.The range of mycorrhizae inoculation effect values was 59.7–71.3%.AMF inoculation increased growth and dry weight of 4-month-old seedlings compared to controls.Dry and total weights of kalapi inoculated with G.coronatum were significantly different from those inoculated with the AMF mixture.However,they are not significantly different from kalapi inoculated with G.claroideum.The results also show that AMF increased nitrogen and phosphorous uptake by the roots,as well as nitrogen,phosphorous,potassium,manganese and iron by the shoots.All AMF treatments decreased potassium uptake in the roots,except in kalapi inoculated with G.coronatum.The AMF mixture decreased iron contents the roots by 15%.AMF can be developed into biofertilizer to support the conservation of kalapi in tropical Indonesia. | Husna Faisal Danu Tuheteru Asrianti Arif | 2021 | Journal of Forestry Research2021，32，2： | 0 |
| 17 | Comparative studies of elemental composition in leaves and flowers of Catharanthus roseus growing in Bangladesh显示文摘Objective:To investigate the elemental composition of the leaves and flowers of Catharanthus roseus(C.roseus) due to the plant's wide application in the indigenous medicinal system and its chemical constituents' importance.Methods:The atomic absorption spectrophotometer was used for quantitative analysis of various elements.Results:Total 13 important elements were analyzed in leaves and flowers of C.roseus.Results indicated the presence of Na,K,Ca,Mg,Cr,Fe,Zn,Al,Cu,Ni,Pb,Cd and Mn in both leaves and flowers.The most important finding of the work was that,leaves of C.roseus showed high concentration of all elements except K and Zn while flowers of C.roseus showed higher concentration of K and Zn.Conclusions:The elemental composition in both leaves and flowers of C.roseus were found to be different.Therefore,different parts of this medicinal plant are enriched in some micro and macro nutrients like Fe,Ca,Na,K,Zn,which are very important for biological metabolic system as well as human health. | Shahin Aziz Koushik Saha Nasim Sultana Husna Parvin Nur Md.Aminul Ahsan Shamim Ahmed Md.Kamal Hossain | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，1： | 0 |
| 18 | MELex: The Construction of Malay-English Sentiment Lexicon显示文摘Currently,the sentiment analysis research in the Malaysian context lacks in terms of the availability of the sentiment lexicon.Thus,this issue is addressed in this paper in order to enhance the accuracy of sentiment analysis.In this study,a new lexicon for sentiment analysis is constructed.A detailed review of existing approaches has been conducted,and a new bilingual sentiment lexicon known as MELex(Malay-English Lexicon)has been generated.Constructing MELex involves three activities:seed words selection,polarity assignment,and synonym expansions.Our approach differs from previous works in that MELex can analyze text for the two most widely used languages in Malaysia,Malay,and English,with the accuracy achieved,is 90%.It is evaluated based on the experimentation and case study approaches where the affordable housing projects in Malaysia are selected as case projects.This finding has given an implication on the ability of MELex to analyze public sentiments in the Malaysian context.The novel aspects of this paper are two-fold.Firstly,it introduces the new technique in assigning the polarity score,and second,it improves the performance over the classification of mixed language content. | Nurul Husna Mahadzir Mohd Faizal Omar Mohd Nasrun Mohd Nawi Anas ASalameh Kasmaruddin Che Hussin Abid Sohail | 2022 | Computers, Materials & Continua2022，，4： | 0 |
| 19 | Microbial Quality of Irrigation Water of Public Parks in Dubai, United Arab Emirates显示文摘 | Munawwar Ali Khan Hessa Saeed Ali Obaid Alkitibi Alia Ali Ahmad Aljanahi Husna Rasool Baksh Rania Dghaim | 2014 | Journal of Environmental Science and Engineering(B)2014，3，4： | 0 |
| 20 | Adherence to medication behavior among tuberculosis patients and their affecting factors:a cross-sectional study at Public Health Center of Wonogiri District, Indonesia显示文摘Objective:This study aimed to identify the influence of predisposing,enabling,and reinforcing factors and the adherence to medication behavior among tuberculosis patients in Selogiri Wonogiri Public Health Center.Methods:This study employed a descriptive cross-sectional research design.A questionnaire was used to collect primary data.Secondary data were obtained from patient treatment cards(Form TB 01).This research was carried out at Selogiri Health Center from November to December 2017.The participants were patients,both new and old patients,who had completed their treatment in the last 2 months or more,recorded from January 2016 to December 2017.A total sampling technique was used in this study.Logistic regression analysis was used to analyze the influence of predisposing,enabling,and reinforcing factors and the adherence to medication among tuberculosis patients.Results:The results of logistic regression analysis indicated that there were four independent variables that have a significant relationship with treatment variables,namely education(odds ratio(OR)=0.025;95%confidence interval(CI)=0.001-0.039);knowledge(OR=3.37;95%CI=0.19-57.71);type of drug(OR=0.448;95%CI=0.012-16.07),and means of transportation(OR=25.77;95%CI=1.33-500.47).Conclusions:Education,knowledge,type of drug,and means of transportation influence medication compliance among tuberculosis patients.Therefore,supporting patients during medication program of tuberculosis is needed to improve their adherence medication during multidrug therapy. | Nita Yunianti Ratnasari Putri Halimu Husna Marni Marni Susana Nurtanti Tantut Susanto | 2020 | Frontiers of Nursing2020，7，3： | 0 |
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