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| 1 | A new design procedure for profile extrusion dles显示文摘 | Hurez P Tanguy P A | 1996 | Polymer Engineering and Science1996，36，5： | 1 |
| 2 | Optimal Design in Profile Extrusion Calibration显示文摘 | L. Fradette P.A. Tanguy F. Thibault P. Sheehy D. Blouin P. Hurez | 1995 | Journal of Polymer Engineering1995，，4： | 1 |
| 3 | A new design procedure for profile extrusion dies显示文摘 | Hurez P Tanguy P A Blouin D | 1996 | Polym Eng Sci1996，36，5： | 1 |
| 4 | Pooled normal human polyspecific IgM contains neutralizing anti-idiotypes to IgG autoantibodies of autoimmune patients and protects from experimental autoimmune disease显示文摘 | Hurez V Kazatchkine MD Vassilev T | 1997 | Blood1997，90，10： | 1 |
| 5 | Numerical simulation of profile extrusion dies without flow separation显示文摘 | Hurez P Tanguy P A | 1993 | Polym Eng Sci1993，33，15： | 1 |
| 6 | On the determination of delamination toughness by using multidirectional DCB specimens显示文摘 | Gong X J Hurez A Verchery G | 2010 | Polymer Testing2010，29，6： | 1 |
| 7 | A new design procedure for profile extrusion dies显示文摘 | HUREZ P TANGUY P A BLOUIN D | 1996 | Polymer Engineering and Science1996，36，5： | 1 |
| 8 | Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells显示文摘 | Witt CM Hurez V Swindle CS | 2003 | Mol Cell Biol2003，23，23： | 1 |
| 9 | A new design procedure for profile extrusion dies 显示文摘 | HUREZ P TANGUY P A | 1996 | Polym Eng and Sci1996，36，5： | 1 |
| 10 | A new design procedure for profile extrusion dies显示文摘 | HUREZ P TANGUY P A BLOUIN D | 1996 | Polym Eng Sci1996，36，5： | 1 |
| 11 | Activated Notch2potentiates CD8 lineage maturation and promotes the selectivedevelopment of B1 B cells 显示文摘 | Witt C M Hurez V Swindle C S | 2003 | Mol Cell Biol2003，23，： | 1 |
| 12 | Design and Analysis of Composite Structures with Interlaced Fibers 显示文摘 | Hurez A Akkus N Verchery G | 2001 | Composites2001，32，10： | 1 |
| 13 | Aging-associated B7-DC^+ B ceils enhance anti-tumor immunity via Th1 and Th17 induction 显示文摘 | Tomihara K Shin T Hurez VJ | 2012 | Aging Cell2012，11，1： | 1 |
| 14 | Design and analysis of composite structures with interlaced fibers 显示文摘 | Hurez A Akkus N Verchery G Kawahara M | 2001 | Composites2001，32，10： | 1 |
| 15 | Human immunoglobulin preparations for intravenous use prevents experimental autoimmune uveoretlnltis显示文摘 | SaoudiA Hurez V de Kazak Y | 1993 | Int Immunol1993，5，： | 1 |
| 16 | Activated Notch2 potentiates CD8 lineage maturation and promotes the selective de- velopment of B1 B cells 显示文摘 | WITT C M HUREZ V SWINDLE C S | 2003 | Mol Cell Biol2003，23，23： | 1 |
| 17 | Notch2 haploinsuffi- ciency results in diminished B1 B cells and a severe reduction in marginal zone B cells 显示文摘 | WITT C M WON W J HUREZ V | 2003 | J Immunol2003，171，6： | 1 |
| 18 | Tumor cell-intrinsic PD-L1 promotes tumor-initiating cellgeneration and functions in melanoma and ovarian cancer显示文摘As tumor PD-L1 provides signals to anti-tumor PD-1^(+)T cells that blunt their functions,αPD-1 andαPD-L1 antibodies have been developed as anti-cancer immunotherapies based on interrupting this signaling axis.However,tumor cell-intrinsic PD-L1 signals also regulate immune-independent tumor cell proliferation and mTOR signals,among other important effects.Tumor-initiating cells(TICs)generate carcinomas,resist treatments and promote relapse.We show here that in murine B16 melanoma and ID8agg ovarian carcinoma cells,TICs express more PD-L1 versus non-TICs.Silencing PD-L1 in B16 and ID8agg cells by shRNA(‘PD-L1lo’)reduced TIC numbers,the canonical TIC genes nanog and pou5f1(oct4),and functions as assessed by tumorosphere development,immune-dependent and immune-independent tumorigenesis,and serial transplantability in vivo.Strikingly,tumor PD-L1 sensitized TIC to interferon-γand rapamycin in vitro.Cell-intrinsic PD-L1 similarly drove functional TIC generation,canonical TIC gene expression and sensitivity to interferon-γand rapamycin in human ES2 ovarian cancer cells.Thus,tumor-intrinsic PD-L1 signals promote TIC generation and virulence,possibly by promoting canonical TIC gene expression,suggesting that PD-L1 has novel signaling effects on cancer pathogenesis and treatment responses. | Harshita B Gupta Curtis A Clark Bin Yuan Gangadhara Sareddy Srilakshmi Pandeswara Alvaro S Padron Vincent Hurez Jose Conejo-Garcia Ratna Vadlamudi Rong Li Tyler J Curiel | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 1 |
| 19 | Aging-associated B7-DC + B ceils enhance anti-tumor immunity via Thl and Thl7 induction 显示文摘 | Tomihara K Shin T Hurez VJ | 2012 | Aging Cell2012，11，1： | 1 |
| 20 | Numerical Simulation of Profile Extrusion Dies Without Flow Separation显示文摘 | Hurez P Tanguy P A Blouin D | 1993 | Polymer Engineering and Science1993，33，15： | 1 |
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