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| 1 | Clinical features and treatment status of hemifacial spasm in China显示文摘 | Wang Lin Hu Xingyue Dong Hongjuan Wang Wenzhao Huang Yue Jin Lingjing Luo Yumin Zhang Weixi Lian Yajun Liang Zhanhua Shang Huifang Feng Yabo wu Yiwen Chen Jun Luo Weifeng Wan Xinhua | 2014 | Chinese Medical Journal2014，，5： | 20 |
| 2 | Precambrian Geochronology, Chronotectonic Framework and Model of Chronocrustal Structure of the Zhongtiao Mountains显示文摘The Zhongtiao Mountains, a typical exposure area of Precambrian rocks, are a concentration area of vari-ous types of copper deposit. The rocks were dated using several dating methods. Based on the age data ob-tained by means of three methods, several aspects are dealt with: (1) the dating results obtained by differentmethods and their geological implications have been compared; (2) a chronotectonic framework has been con-structed by means of these reliable ages, which indicates that the ages of the rocks of the Proterozoic mobilebelt fall in a time span of 2400 to 2000 Ma during which global magmatic records are lacking and reflects theages of important events in the mobile belt; (3) according to the ages of inherited zircons, neodymium modelage of the depleted mantle sources (TDM) and geochemical and geological data, a model of Precambrianchronocrustal structure has been constructed, representing a typical for the North China craton. | Sun Dazhong Li Huimin Lin Yuanxian Zhou Huifang Zhao Fengqing Tang Min Tianjin Institute of Geology and Mineral Resources, Chinese Academy of Geological Sciences, Tianjin Fei Zhenbi | 1992 | Acta Geologica Sinica(English Edition)1992，66，1： | 10 |
| 3 | Salvianolic acid A alleviates renal injury in systemic lupus erythematosus induced by pristane in BALB/c mice显示文摘The purpose of this study was to investigate the effects of salvianolic acid A(SAA) in systemic lupus erythematosus(SLE) induced by pristane in BALB/c mice.Lupus mice were established by confirming elevated levels of autoantibodies and IL-6 after intraperitoneal injection of pristane.Mice were then treated with daily oral doses of SAA for 5 months in parallel with mice treated with prednisone and aspirin as positive controls.The levels of autoantibodies were monitored at monthly intervals and nephritic symptoms observed by hematoxylin and eosin(H&E) and periodic acid-Schiff(PAS) staining.Western blot analysis of renal tissue was also employed.SAA treatment caused a significant reduction in the levels of anti-Sm autoantibodies and reduced renal histopathological changes and pathological effects.SAA treatment also significantly inhibited the phosphorylation of IKK,IκB and NFκB in renal tissues of lupus mice.In conclusion,the results suggest that SAA alleviates renal injury in pristane-induced SLE in BALB/c mice through inhibition of phosphorylation of IKK,IκB and NFκB. | Yihuang Lin Yu Yan Huifang Zhang Yucai Chen Yangyang He Shoubao Wang Lianhua Fang Yang Lv Guanhua Du | 2017 | Acta Pharmaceutica Sinica B2017，7，2： | 8 |
| 4 | Detection and suppression of narrow band RFI for synthetic aperture radar imaging显示文摘Radio frequency interference(RFI) is becoming more and more frequently, which makes it an important issue in SAR imaging.RFI presented in synthetic aperture radar either on purpose or inadvertent will distort the useful SAR echoes, thus degrade the SAR image quality.To resolve this issue, a long time study was carried out to study the characteristic of the RFI through the RFIaffected spaceborne and airborne SAR data.Based on the narrow band nature of RFI, this paper proposes a new process which contains both RFI detection and RFI suppression.A useful subband spectral kurtosis detector is first used to detect RFI, and then its results are used for RFI suppression.The proposed process has two advantages: one is the economization on the compute time for unnecessary interference suppression when no RFI existed; the other is improving the performance of the suppression method with knowing the exact position where RFI is.Moreover, the previous RFI suppression method––subband spectral cancelation(SSC) is supplemented and perfected.The subband division step is also elaborated detail in this paper.The experiment results show that the subband spectral kurtosis detector exhibits good performance in recognizing both weak and narrow-band RFI.In addition, the validity of the SSC method with subband spectral kurtosis detector is also validated on the real SAR echoes. | Yang Lin Zheng Huifang Feng Jin Li Ning Chen Jiaqi | 2015 | Chinese Journal of Aeronautics2015，28，4： | 8 |
| 5 | Efficacy and advantages of modified Traditional Chinese Medicine treatments based on'kidney reinforcing'for chronic aplastic ane-mia:a randomized controlled clinical trial显示文摘OBJECTIVE:To compare the efficacy of modified treatments based on 'kidney reinforcing' in the management of chronic aplastic anemia(CAA),and explore their advantages and specialties.METHODS:One hundred and eleven patients with CAA were randomly divided into three groups:kidney reinforcing alone(KA),'kidney reinforcing and Qi tonifying'(KQ),and 'kidney reinforcing and blood circulation invigorating'(KC).Normal and positive control groups were also formed.All patients were treated for 6 months(two courses).Hemograms,Traditional Chinese Medicine(TCM) syndrome scores,and therapeutic effects were assessed,and changes in T-lymphocyte subsets,regulatory T cells and cytokines were detected.RESULTS:The KQ and KC groups had lower TCM syndrome scores than the positive control group after 6 months(P < 0.05).The KQ group had a higher overall efficacy than the positive control group after 3 months(P < 0.05),while platelet counts increased in the KC group after 6 months(P < 0.05).CD3+ T-lymphocyte ratios decreased only in the KQ group,while CD3 + CD4 + CD8-Tlymphocytes increased only in the KC group after 6 months(P <0.05).Levels of interferon-γ,tumor necrosis fac-tor-α,interleukin(IL)-2 and IL-6 decreased and levels of IL-4 and IL-10 increased in all treated groups after 6 months.Levels of IL-6 in the KQ and KC groups were lower than those in the positive control group(P < 0.05).CONCLUSION:Treatments based on kidney reinforcing have a rebalancing effect on cytotoxic and T helper cells,and regulate expression of interferon-γ,IL-2,IL-6 and IL-4.KQ may be more effective in treating CAA,and KC may have an advantage in platelet recovery. | Wu Dijiong Shen Yiping Ye Baodong Fang Bingmu Lin Shengyun Chen Zhilu Jiang Huifang Feng Changwei He Lüyuan Gao Yanting Liu Yonglin Liu Yonghua Zhu Jiajia Wu Liqiang Shao Keding Zhou Yuhong | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 6 |
| 6 | Anti-hyperglycemic effects of dihydromyricetin in streptozotocin-induced diabetic rats显示文摘Dihydromyricetin(DHM),as a bioactive flavanonol compound,is mainly found in“Tengcha”(Ampelopsis grossedentata)cultivated in south of China.This study aimed to investigate the anti-hyperglycemic and antidyslipidemic activities of DHM using type 2 diabetes mellitus(T2D)rats,which was induced by feeding with high fat and fructose diet for 42 days and intraperitoneal administration of streptozocin.Forty-eight freshlyweaned rats were randomly assigned into the negative control(Blank),low dose(100 mg/kg),medium dose(200 mg/kg),high dose(400 mg/kg),and positive(40 mg/kg,met)groups.Fasting blood glucose and body weight were measured at weekly interval.Oral glucose tolerance tests were performed on days 42.The results revealed that DHM possessed significant antihyperglycaemic and antihyperinsulinemic effects.Moreover,after the DHM treatment,p-Akt and p-AMPK expression was upregulated,and glycogen synthase kinase-3β(GSK-3β)expression was downregulated,indicating that the potential anti-diabetic mechanism of DHM might be due to the regulation of the AMPK/Akt/GSK-3βsignaling pathway. | Maojun Yao Hui Teng Qiyan Lv Huifang Gao Tengming Guo Yiwen Lin Sihai Gao Meihu Ma Lei Chen | 2021 | Food Science and Human Wellness2021，10，2： | 6 |
| 7 | An Experimental Study on Optimization of Large-volume Airgun Source Excitation Conditions in a Reservoir显示文摘Through manual pickup of seismic phases,the number of recording stations,the farthest observation distance of station and received energy are determined,then optimal operating condition processing software is developed to evaluate the excitation effect of operating conditions. The optimal operating conditions in the Mianhuatan Reservoir are determined using this software. They are: optimal water depth 25 m,airgun array sink depth 9m and airgun array size 7m × 7m. At the same time,accumulative stacking results for every 10 times are analyzed for 300 fixed-point excitations. It is concluded that the excitation effect shows a rapidly rising trend at 10 to 90 times stacking,a slowly rising trend at 100 to 150 times stacking,a rapidly rising trend at 160 to 240 times stacking,and a slowly rising trend at 250 to 300 times stacking. As the number of stacking increases,the propagation distance and the number of recording stations also increase gradually. | Chen Huifang Lin Binhua Jin Xing Wu Lihua Cai Huiteng | 2016 | Earthquake Research in China2016，30，3： | 4 |
| 8 | Comparison of in vitro digestion methods for determining bioaccessibility of Hg in rice of China显示文摘Rice consumption can be a major pathway for mercury(Hg) exposure, which can cause health hazards to Chinese residents. To accurately assess the potential health risks, the bioaccessibility of Hg in rice samples collected at background and Hg-contamination sites was examined using four in vitro methods. The results showed that < 50% of the total mercury(THg) was bioaccessible in the studied rice samples. The THg bioaccessibility in the rice samples collected at the Hg-contaminated site was higher than that observed at the background area. The bioaccessibility of arsenic(As) and cadmium(Cd) was also evaluated for comparison of the four in vitro methods used in this study. The Physiologically Based Extraction Test was found to be the most accurate method based on the consistency of the results compared to those reported in previous studies. The estimated daily intakes of THg via rice consumption using the bioaccessibility data were found to meet the recommendation value set by the JECFA and the WHO in both sites. However, the potential health risk was not negligible at the Hg-contaminated sites, due to the high THg concentration and bioaccessibility in the rice samples. | Ze Wu Xinbin Feng Ping Li Che-Jen Lin Guangle Qiu Xun Wang Huifang Zhao Hui Dong | 2018 | Journal of Environmental Sciences2018，30，6： | 3 |
| 9 | The promoting effect of low-level sulfidation in PdCuS nanoparticles catalyzed alkyne semihydrogenation显示文摘硫来源的支持的效果是吸引人却糟糕听说的现象。此处,我们与硫粉末的不同数量学习了 PdCu 二金属的 nanoparticles (NP ) 的处理。低级 sulfidation 导致了由表面组成的 Pd30Cu10S9 NP 催化剂的产生充实的 Pd NP,电子缺乏的 Pd 和 Cu,以及零原子价硫。Pd30Cu10S9 NP 催化剂在炔属羟的 semihydrogenation 显示出显着地提高的活动和选择。我们的学习第一次在原子水平为硫的支持的效果揭示了一个可能的原因,建议在催化剂设计的新策略。 | Cai Wu Yifeng Chen Rongan Shen Wei Zhu Yue Gong Lin Gu Qing Peng Huifang Guo Wei He | 2018 | Nano Research2018，11，9： | 2 |
| 10 | Deep Analysis of Power Equipment Defects Based on Semantic Framework Text Mining Technology显示文摘Defect factors and their relevant rules can be analyzed in depth by processing defect records which are often expressed in the form of text data.However,considering that defect text consists of both structured and unstructured data,it is necessary to excavate structured information from unstructured data.In this paper,a text mining method based on semantic framework technology is introduced to transform unstructured defect description into structured information such as components and defect attributes.Then,a deep analyzing model of a power equipment defect is established,which provides a scheme of defect mining based on historical defect texts.Case studies prove that the proposed deep analysis method has a guiding significance for equipment upgrading,selection and maintenance. | Huifang Wang Jing Cao Dongyang Lin | 2022 | CSEE Journal of Power and Energy Systems2022，8，4： | 2 |
| 11 | Some critical structure factors of titanium oxide nano?tube array in its photocatalytic activity显示文摘 | Zhuang Huifang Lin Changjian Lai Yuekun | 2007 | Environ?mental Science and Technology2007，41，13： | 1 |
| 12 | A review: recent advances and future prospects of taxol-producing endophytic fungi显示文摘 | Xuanwei Zhou Huifang Zhu Lu Liu Juan Lin Kexuan Tang | 2010 | Applied Microbiology and Biotechnology2010，，6： | 1 |
| 13 | Basic-leucine zipper 17 and Hmg-CoA reductase degradation 3A are involved in salt acclimation memory in Arabidopsis显示文摘Salt acclimation, which is induced by previous salt exposure, increases the resistance of plants to future exposure to salt stress. However, little is known about the underlying mechanism, particularly how plants store the'memory' of salt exposure. In this study, we established a system to study salt acclimation in Arabidopsis thaliana. Following treatment with a low concentration of salt, seedlings were allowed to recover to allow transitory salt responses to subside while maintaining the sustainable effects of salt acclimation. We performed transcriptome profiling analysis of these seedlings to identify genes related to salt acclimation memory. Notably, the expres-sion of Basic-leucine zipper 17 (bZIP17) and Hmg-CoA reductase degradation 3A (HRD3A), which are important in the unfolded protein response (UPR) and endoplasmic reticulum-associated degradation (ERAD), respectively, increased following treatment with a low concentration of salt and remained at stably high levels after the stimulus was removed, a treatment which improved plant tolerance to future high-salinity challenge. Our findings suggest that the upregulated expression of important genes involved in the UPR and ERAD represents a 'memory' of the history of salt exposure and enables more potent responses to future exposure to salt stress, providing new insights into the mechanisms underlying salt acclimation in plants. | Lin Tian Yan Zhang Erfang Kang Huifang Ma Huan Zhao Ming Yuan Lei Zhu Ying Fu | 2019 | Journal of Integrative Plant Biology2019，61，10： | 1 |
| 14 | Prevalence of Antibiotic Resistance Genes and Bacterial Pathogens in Long-Term Manured Greenhouse Soils As Revealed by Metagenomic Survey显示文摘 | FANG Hua WANG Huifang CAI Lin | 2015 | Environ Sci Technol2015，49，2： | 1 |
| 15 | Chlorophyll Fluorescence Extraction from Water-Leaving Radiance of Algae-Containing Water Through Polarization显示文摘When measuring reflectance spectra, it is very important to accurately extract chlorophyll fluorescence from elastic-scattering light in water-leaving radiance. The elastic scattering of light by water particles produces partially polarized light. In contrast, chlorophyll fluorescence in planktonic algae yields completely unpolarized light. These properties can be used to separate fluorescent signals from the water-leaving radiance and thus to determine chlorophyll concentration. The algal species Aureococcus anophagefferens was used to conduct a laboratory polarization experiment. For the tests, we used a field spectroradiometer and a polarizer; measurements were collected using two different observation modes. The chlorophyll fluorescence curve extracted through polarization shows an excellent match with the results obtained using the fluorospectro photometer for both measurement modes, suggesting that polarization-based chlorophyll fluorescence extraction may be feasible. The extracted fluorescence is more reliable at incident zenith angles ranging from 30? to 60?. For algae-containing water, the results improve with increasing chlorophyll concentration. This method could help improve chlorophyll concentration measurement and the remote-sensing detection of resulting harmful algae blooms. | WANG Lin QIU Zhongfeng PANG Huifang LIU Yongjian CHEN Yanlong JIANG Lingling | 2017 | Journal of Ocean University of China2017，16，6： | 1 |
| 16 | A bioinformatic evaluation of potential allergenicity of 85 candidate genes in transgenic organisms显示文摘The potential of genetically modified organisms(GMOs) to increase allergenicity or predispositions to allergies has attracted much attention.An approach that will properly and holistically evaluate the allergenicity of GMOs is yet to be found.Here,85 transgenes that have been reported in both international and domestic studies during recent years are summarized case by case;49 of the transformed genes were from plant sources and 36 were from animal sources.EVALLERTM,a web server for the in silico assessment of potential protein allergenicity,was used to evaluate the potential of the transgenic proteins as allergens.The biomedical journals listed in Highwire(http://gffzzd58bc32f34884012hkuf5qfpqkqq56kuf.ffgz.tsg.suse.edu.cn/) were searched and reviewed to decipher whether any of the transformed genes were linked to allergenicity or human health.The EVALLER analysis identified 5 allergenic genes,whilst our literature review found 11 genes that were either related to allergic cases or to clinical adverse events;all 16 of these genes have been used in GMOs.The analysis pathway that we have developed can help guide the selection of genes to be used in genetic modification.The pathway also provides a paradigm for allergenicity analysis of transgene candidates. | ZOU ZeHong HE Ying RUAN Lin SUN BaoQing CHEN HuiFang CHEN De LIU ShiMing YANG XiaoGuang TAO AiLin | 2012 | Chinese Science Bulletin2012，57，15： | 1 |
| 17 | Polystyrene microsphere-immobilized palladium(Ⅱ)porphyrin as mild,reusable,and highly efficient catalyst for Heck reaction显示文摘A novel Heck reaction catalyst consisting of a palladium(Ⅱ) complex of meso-tetra(phydroxyphenyl)porphyrin(MTP) and cross-linked chloromethylated polystyrene microspheres(PMs) was successfully prepared via covalent ether bonds between the chloride groups in the PMs and the hydroxyl groups in MTP.The catalyst was characterized using scanning electron microscopy,Fourier-transform infrared spectroscopy,and inductively coupled plasma atomic emission spectroscopy(ICP-AES).This polystyrene-supported palladium-complex was an efficient heterogeneous catalyst for cross-coupling of aryl iodides with ethyl acrylate.The reaction of iodobenzene and ethyl acrylate under N_2 at 100 ℃ and a catalyst concentration of 0.1%gave a gas chromatography product yield of 99.8%,which is much higher than that achieved using a free palladium(Ⅱ) complex of MTP as the catalyst(41.3%).The catalyst was recycled up to six times without significant loss of catalytic activity.These results suggest that the immobilized palladium(Ⅱ)-MTP catalyst has potential applications in synthetic and industrial chemistry. | Yinbin Huang Liangrong Yang Minghui Huang Jian Wang Lin Xu Wensong Li Huacong Zhou Xitong Sun Huifang Xing Huizhou Liu | 2015 | Particuology2015，13，5： | 1 |
| 18 | Research on Real-time Monitoring of Abnormal Seismic Noise显示文摘The noise data in vertical component records of 85 seismic stations in Fujian Province during 2012 is used as the research object in this paper. The noise data is divided into fiveminute segments to calculate the power spectra. The high reference line and low reference line of station are then identified by drawing a probability density function graph( PDF)using the power spectral probability density function. Moreover, according to the anomalies of PDF graphs in 85 seismic stations,the abnormal noise is divided into four categories: dropped packet, low noise, high noise, and median noise anomalies.Afterwards,four selection methods are found by the high or low noise reference line of the stations,and the system of real-time monitoring of seismic noise is formed by combining the four selection methods. Noise records of 85 seismic stations in Fujian Province in July2013 are selected for verification,and the results show that the anomalous noise-recognition system could reach a 90% success rate at most stations and the effect of selection are very good. Therefore,it could be applied to the seismic noise real-time monitoring in stations. | Lin Binhua Jin Xing Liao Shirong Li Jun Huang Linzhu Chen Huifang | 2016 | Earthquake Research in China2016，30，2： | 1 |
| 19 | Effects of Pulsed Electromagnetic Fields on Bone Mass and Wnt/β-Catenin Signaling Pathway in Ovariectomized Rats显示文摘 | Jun Zhou Hongchen He Lin Yang Shiju Chen Hua Guo Lu Xia Huifang Liu Yuxi Qin Chuan Liu Xiaofei Wei Yujing Zhou Chengqi He | 2012 | Archives of Medical Research2012，，4： | 1 |
| 20 | Facile anion-exchange synthesis of BiOI/BiOBr composite with enhanced photoelectrochemical and photocatalytic properties显示文摘 | Haili Lin Huifang Ye Xin Li Jing Cao Shifu Chen | 2014 | Ceramics International2014，，： | 1 |
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