| 1 | The role of cholesterol metabolism in leukemia显示文摘Leukemia is a common hematological malignancy with overall poor prognosis.Novel therapies are needed to improve the outcome of leukemia patients.Cholesterol metabolism reprogramming is a featured alteration in leukemia.Many metabolic-related genes and metabolites are essential to the progress and drug resistance of leukemia.Exploring potential therapeutical targets related to cholesterol homeostasis is a promising area.This review summarized the functions of cholesterol and its derived intermediate metabolites,and also discussed potential agents targeting this metabolic vulnerability in leukemia. | Liang Zhao Huien Zhan Xinya Jiang Yangqiu Li Hui Zen | 2019 | Blood Science2019，1，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员